Porous synthetic vascular grafts with oriented ingrowth channels
    10.
    发明授权
    Porous synthetic vascular grafts with oriented ingrowth channels 失效
    具有定向向内生长通道的多孔合成血管移植物

    公开(公告)号:US08187319B2

    公开(公告)日:2012-05-29

    申请号:US12780098

    申请日:2010-05-14

    IPC分类号: A61F2/06

    摘要: A vascular prosthesis is constructed from a structure having interconnected, helically oriented channel-porosity to allow oriented ingrowth of connective tissue into a wall of the prosthesis. The prosthesis can have a small internal diameter of 6 mm or less. Several different methods can be used to produce the prosthesis, including a fiber winding and extraction technique, a melt extrusion technique, and a particle and fiber extraction technique using either a layered method or a continuous method. Furthermore, mechanical properties of prosthesis are matched with mechanical properties of the host vessel, thereby overcoming problems of compliance mismatch.

    摘要翻译: 血管假体由具有相互连接的螺旋形取向的通道孔隙的结构构成,以允许结缔组织的定向向内生长进入假体的壁。 假体可以具有6mm或更小的小内径。 可以使用几种不同的方法来生产假体,包括纤维缠绕和提取技术,熔体挤出技术以及使用分层方法或连续方法的颗粒和纤维提取技术。 此外,假体的机械性能与主体容器的机械性能相匹配,从而克服了柔顺性失配的问题。