公开(公告)号：US20210353187A1

公开(公告)日：2021-11-18

申请号：US17390460

申请日：2021-07-30

Applicant: DexCom, Inc.

Inventor： Mark C. Shults ,  Rathbun K. Rhodes ,  Stuart J. Updike ,  James H. Brauker

IPC: A61B5/145 ,  A61B5/1486 ,  A61B5/00 ,  A61B5/1495 ,  A61B5/15

Abstract: The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous and subcutaneous measurement of glucose in a host.

公开(公告)号：US10265000B2

公开(公告)日：2019-04-23

申请号：US15668541

申请日：2017-08-03

Applicant: DexCom, Inc.

Inventor： Mark C. Shults ,  Rathbun K. Rhodes ,  Stuart J. Updike ,  James H. Brauker

IPC: A61B5/05 ,  A61B5/145 ,  A61B5/1486 ,  A61B5/00 ,  A61B5/1495 ,  A61B5/15

Abstract: The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous and subcutaneous measurement of glucose in a host.

公开(公告)号：US20190021596A1

公开(公告)日：2019-01-24

申请号：US16137411

申请日：2018-09-20

Applicant: DexCom, Inc.

Inventor： Mark Brister ,  Paul V. Neale ,  Peter C. Simpson ,  James H. Brauker ,  James Patrick Thrower ,  Mark Shults ,  Rathbun K. Rhodes ,  Paul V. Goode, JR. ,  Arnold L. Holmquist

IPC: A61B5/00 ,  A61B5/1473 ,  A61B5/145 ,  A61B5/07

Abstract: The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous measurement of glucose in a host.

公开(公告)号：US09833143B2

公开(公告)日：2017-12-05

申请号：US14296735

申请日：2014-06-05

Applicant: DexCom, Inc.

Inventor： Mark Brister ,  Paul V. Neale ,  Peter C. Simpson ,  James H. Brauker ,  James Patrick Thrower ,  Mark Shults ,  Rathbun K. Rhodes ,  Paul V. Goode, Jr. ,  Arnold L. Holmquist

IPC: A61B5/1473 ,  H04B1/03 ,  A61B5/00 ,  A61B5/07 ,  A61B5/145

CPC classification number: A61B5/0015 ,  A61B5/0031 ,  A61B5/076 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/1473 ,  A61B2560/04 ,  A61B2560/0462 ,  A61B2562/247 ,  H04B1/03

Abstract: The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous measurement of glucose in a host.

公开(公告)号：US20160022186A1

公开(公告)日：2016-01-28

申请号：US14875539

申请日：2015-10-05

Applicant: DexCom, Inc.

Inventor： Mark A. Tapsak ,  Rathbun K. Rhodes ,  Mark C. Shults ,  Jason D. McClure

IPC: A61B5/1486 ,  A61B5/145

CPC classification number: A61B5/14865 ,  A61B5/14532 ,  A61B5/1473 ,  A61B5/1486 ,  A61B2562/028 ,  A61B2562/125 ,  A61L31/12 ,  B01D69/141 ,  B01D71/54 ,  B01D71/80 ,  B05D3/007 ,  B05D5/00 ,  C12Q1/002 ,  C12Q1/006 ,  Y10T428/31551

Abstract: The invention provides an implantable membrane for regulating the transport of analytes therethrough that includes a matrix including a first polymer; and a second polymer dispersed throughout the matrix, wherein the second polymer forms a network of microdomains which when hydrated are not observable using photomicroscopy at 400× magnification or less. In one aspect, the homogeneous membrane of the present invention has hydrophilic domains dispersed substantially throughout a hydrophobic matrix to provide an optimum balance between oxygen and glucose transport to an electrochemical glucose sensor.

公开(公告)号：US20150374270A1

公开(公告)日：2015-12-31

申请号：US14842276

申请日：2015-09-01

Applicant: DexCom, Inc.

Inventor： Mark C. Shults ,  Rathbun K. Rhodes ,  Stuart J. Updike ,  James H. Brauker

IPC: A61B5/1486 ,  A61B5/145

CPC classification number: A61B5/14532 ,  A61B5/0002 ,  A61B5/0031 ,  A61B5/145 ,  A61B5/14503 ,  A61B5/14865 ,  A61B5/1495 ,  A61B5/150022 ,  A61B5/6846

Abstract: The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous and subcutaneous measurement of glucose in a host.

Abstract translation: 本发明一般涉及用于测量宿主中分析物的系统和方法。 更具体地，本发明涉及用于经皮和皮下测量宿主中葡萄糖的系统和方法。

公开(公告)号：US20140128700A1

公开(公告)日：2014-05-08

申请号：US14144497

申请日：2013-12-30

Applicant: DexCom, Inc.

Inventor： Mark C. Shults ,  Stuart J. Updike ,  Rathbun K. Rhodes

IPC: A61B5/1486 ,  A61B5/00 ,  A61B5/1495 ,  A61B5/145

CPC classification number: A61B5/14865 ,  A61B5/0004 ,  A61B5/14532 ,  A61B5/1495 ,  C12Q1/006

Abstract: Devices and methods for determining analyte levels are described. The devices and methods allow for the implantation of analyte-monitoring devices, such as glucose monitoring devices, that result in the delivery of a dependable flow of blood to deliver sample to the implanted device. The devices comprise a unique microarchitectural arrangement in the sensor region that allows accurate data to be obtained over long periods of time.

Abstract translation: 描述了用于确定分析物水平的装置和方法。 装置和方法允许植入分析物监测装置，例如葡萄糖监测装置，其导致输送可靠的血液流以将样品递送到植入的装置。 这些设备包括传感器区域中的独特的微架构布置，允许在长时间段内获得准确的数据。

公开(公告)号：US20130030273A1

公开(公告)日：2013-01-31

申请号：US13631780

申请日：2012-09-28

Applicant: DexCom, Inc.

Inventor： Mark A. Tapsak ,  Rathbun K. Rhodes ,  Mark C. Shults ,  Jason D. McClure

IPC: A61B5/145 ,  B05D5/00

CPC classification number: A61B5/14865 ,  A61B5/14532 ,  A61B5/1473 ,  A61B5/1486 ,  A61B2562/028 ,  A61B2562/125 ,  A61L31/12 ,  B01D69/141 ,  B01D71/54 ,  B01D71/80 ,  B05D3/007 ,  B05D5/00 ,  C12Q1/002 ,  C12Q1/006 ,  Y10T428/31551

Abstract: The invention provides an implantable membrane for regulating the transport of analytes therethrough that includes a matrix including a first polymer; and a second polymer dispersed throughout the matrix, wherein the second polymer forms a network of microdomains which when hydrated are not observable using photomicroscopy at 400× magnification or less. In one aspect, the homogeneous membrane of the present invention has hydrophilic domains dispersed substantially throughout a hydrophobic matrix to provide an optimum balance between oxygen and glucose transport to an electrochemical glucose sensor.

Abstract translation: 本发明提供了一种用于调节分析物通过其的运输的可植入膜，其包括包含第一聚合物的基质; 和分散在整个基质中的第二种聚合物，其中第二种聚合物形成微区网络，当400×放大倍率或更小时，使用光学显微镜不能观察到水合。 在一个方面，本发明的均质膜具有基本上分散在疏水性基质上的亲水性畴，以提供氧和葡萄糖转运到电化学葡萄糖传感器之间的最佳平衡。