公开(公告)号：US11596332B2

公开(公告)日：2023-03-07

申请号：US17390460

申请日：2021-07-30

Applicant: DexCom, Inc.

Inventor： Mark C. Shults ,  Rathbun K. Rhodes ,  Stuart J. Updike ,  James H. Brauker

IPC: A61B5/145 ,  A61B5/1486 ,  A61B5/00 ,  A61B5/1495 ,  A61B5/15

Abstract: The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous and subcutaneous measurement of glucose in a host.

公开(公告)号：US11191458B2

公开(公告)日：2021-12-07

申请号：US16284768

申请日：2019-02-25

Applicant: DexCom, Inc.

Inventor： Mark C. Shults ,  Rathbun K. Rhodes ,  Stuart J. Updike ,  James H. Brauker

IPC: A61B5/145 ,  A61B5/1486 ,  A61B5/00 ,  A61B5/1495 ,  A61B5/15

Abstract: The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous and subcutaneous measurement of glucose in a host.

公开(公告)号：US09439589B2

公开(公告)日：2016-09-13

申请号：US14553382

申请日：2014-11-25

Applicant: DexCom, Inc.

Inventor： Mark C. Shults ,  Stuart J. Updike ,  Rathbun K. Rhodes ,  Barbara J. Gilligan ,  Mark A. Tapsak

IPC: A61B5/00 ,  A61B5/1486 ,  A61B5/145 ,  A61B5/1455 ,  C12Q1/00

CPC classification number: A61B5/14532 ,  A61B5/0031 ,  A61B5/1455 ,  A61B5/14558 ,  A61B5/1459 ,  A61B5/1486 ,  A61B5/14865 ,  A61B2562/17 ,  C12Q1/006

Abstract: Devices and methods for determining analyte levels are described. The devices and methods allow for the implantation of analyte-monitoring devices, such as glucose monitoring devices that result in the delivery of a dependable flow of blood to deliver sample to the implanted device. The devices include unique architectural arrangement in the sensor region that allows accurate data to be obtained over long periods of time.

公开(公告)号：US20140378798A1

公开(公告)日：2014-12-25

申请号：US14482458

申请日：2014-09-10

Applicant: DexCom, Inc.

Inventor： Mark A. Tapsak ,  Rathbun K. Rhodes ,  Mark C. Shults ,  Jason D. McClure

IPC: A61B5/1473 ,  B05D5/00 ,  B05D3/00 ,  A61B5/145

CPC classification number: A61B5/14865 ,  A61B5/14532 ,  A61B5/1473 ,  A61B5/1486 ,  A61B2562/028 ,  A61B2562/125 ,  A61L31/12 ,  B01D69/141 ,  B01D71/54 ,  B01D71/80 ,  B05D3/007 ,  B05D5/00 ,  C12Q1/002 ,  C12Q1/006 ,  Y10T428/31551

Abstract: The invention provides an implantable membrane for regulating the transport of analytes therethrough that includes a matrix including a first polymer; and a second polymer dispersed throughout the matrix, wherein the second polymer forms a network of microdomains which when hydrated are not observable using photomicroscopy at 400× magnification or less. In one aspect, the homogeneous membrane of the present invention has hydrophilic domains dispersed substantially throughout a hydrophobic matrix to provide an optimum balance between oxygen and glucose transport to an electrochemical glucose sensor.

Abstract translation: 本发明提供了一种用于调节分析物通过其的运输的可植入膜，其包括包含第一聚合物的基质; 和分散在整个基质中的第二种聚合物，其中第二种聚合物形成微区网络，当400×放大倍率或更小时，使用光学显微镜不能观察到水合。 在一个方面，本发明的均质膜具有基本上分散在疏水性基质上的亲水性畴，以提供氧和葡萄糖转运到电化学葡萄糖传感器之间的最佳平衡。

公开(公告)号：US20190183396A1

公开(公告)日：2019-06-20

申请号：US16284768

申请日：2019-02-25

Applicant: DexCom, Inc.

Inventor： Mark C. Shults ,  Rathbun K. Rhodes ,  Stuart J. Updike ,  James H. Brauker

IPC: A61B5/145 ,  A61B5/00 ,  A61B5/15 ,  A61B5/1486 ,  A61B5/1495

CPC classification number: A61B5/14532 ,  A61B5/0002 ,  A61B5/0031 ,  A61B5/145 ,  A61B5/14503 ,  A61B5/14865 ,  A61B5/1495 ,  A61B5/150022 ,  A61B5/6846

Abstract: The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous and subcutaneous measurement of glucose in a host.

公开(公告)号：US20190083018A1

公开(公告)日：2019-03-21

申请号：US16185957

申请日：2018-11-09

Applicant: DexCom, Inc.

Inventor： Mark A. Tapsak ,  Rathbun K. Rhodes ,  Mark C. Shults ,  Jason D. McClure

IPC: A61B5/1486 ,  B05D5/00 ,  B05D3/00 ,  A61B5/1473 ,  A61B5/145 ,  C12Q1/00 ,  B01D71/80 ,  B01D71/54 ,  B01D69/14 ,  A61L31/12

Abstract: The invention provides an implantable membrane for regulating the transport of analytes therethrough that includes a matrix including a first polymer; and a second polymer dispersed throughout the matrix, wherein the second polymer forms a network of microdomains which when hydrated are not observable using photomicroscopy at 400× magnification or less. In one aspect, the homogeneous membrane of the present invention has hydrophilic domains dispersed substantially throughout a hydrophobic matrix to provide an optimum balance between oxygen and glucose transport to an electrochemical glucose sensor.

公开(公告)号：US20180192926A1

公开(公告)日：2018-07-12

申请号：US15913785

申请日：2018-03-06

Applicant: DexCom, Inc.

Inventor： Mark C. Shults ,  Stuart J. Updike ,  Rathbun K. Rhodes ,  Barbara J. Gilligan ,  Mark A. Tapsak

IPC: A61B5/145 ,  A61B5/1486 ,  A61B5/00 ,  A61B5/1455 ,  C12Q1/00

CPC classification number: A61B5/0031 ,  A61B5/14532 ,  A61B5/1455 ,  A61B5/14558 ,  A61B5/1459 ,  A61B5/1486 ,  A61B5/14865 ,  A61B2562/17 ,  C12Q1/006

Abstract: Devices and methods for determining analyte levels are described. The devices and methods allow for the implantation of analyte-monitoring devices, such as glucose monitoring devices that result in the delivery of a dependable flow of blood to deliver sample to the implanted device. The devices include unique architectural arrangement in the sensor region that allows accurate data to be obtained over long periods of time.

公开(公告)号：US09931067B2

公开(公告)日：2018-04-03

申请号：US15264577

申请日：2016-09-13

Applicant: DexCom, Inc.

Inventor： Mark C. Shults ,  Stuart J. Updike ,  Rathbun K. Rhodes ,  Barbara J. Gilligan ,  Mark A. Tapsak

IPC: A61B5/00 ,  A61B5/145 ,  A61B5/1455 ,  A61B5/1486 ,  C12Q1/00 ,  A61B5/1459

CPC classification number: A61B5/14532 ,  A61B5/0031 ,  A61B5/1455 ,  A61B5/14558 ,  A61B5/1459 ,  A61B5/1486 ,  A61B5/14865 ,  A61B2562/17 ,  C12Q1/006

Abstract: Devices and methods for determining analyte levels are described. The devices and methods allow for the implantation of analyte-monitoring devices, such as glucose monitoring devices that result in the delivery of a dependable flow of blood to deliver sample to the implanted device. The devices include unique architectural arrangement in the sensor region that allows accurate data to be obtained over long periods of time.

公开(公告)号：US20180055361A1

公开(公告)日：2018-03-01

申请号：US15798097

申请日：2017-10-30

Applicant: DexCom, Inc.

Inventor： Mark C. Brister ,  Paul V. Neale ,  Peter C. Simpson ,  James H. Brauker ,  James Patrick Thrower ,  Mark Shults ,  Rathbun K. Rhodes ,  Paul V. Goode, JR. ,  Arnold L. Holmquist

IPC: A61B5/00 ,  A61B5/1473 ,  A61B5/145 ,  A61B5/07

CPC classification number: A61B5/0015 ,  A61B5/0031 ,  A61B5/076 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/1473 ,  A61B2560/04 ,  A61B2560/0462 ,  A61B2562/247 ,  H04B1/03

Abstract: The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous measurement of glucose in a host.

公开(公告)号：US20170325726A1

公开(公告)日：2017-11-16

申请号：US15668541

申请日：2017-08-03

Applicant: DexCom, Inc.

Inventor： Mark C. Shults ,  Rathbun K. Rhodes ,  Stuart J. Updike ,  James H. Brauker

IPC: A61B5/145 ,  A61B5/15 ,  A61B5/1495 ,  A61B5/1486 ,  A61B5/00

CPC classification number: A61B5/14532 ,  A61B5/0002 ,  A61B5/0031 ,  A61B5/145 ,  A61B5/14503 ,  A61B5/14865 ,  A61B5/1495 ,  A61B5/150022 ,  A61B5/6846

Abstract: The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous and subcutaneous measurement of glucose in a host.