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190 条记录 (耗时 0.038 秒)

    Enzyme inhibitor compounds
    32.
    发明授权
    Enzyme inhibitor compounds 有权

    公开(公告)号：US09150574B2

    公开(公告)日：2015-10-06

    申请号：US14344417

    申请日：2011-09-14

    申请人： David Evans ,  Allison Carley ,  Alison Stewart ,  Michael Higginbottom ,  Edward Savory ,  Iain Simpson ,  Marianne Nilsson ,  Martin Haraldsson ,  Erik Nordling ,  Tobias Koolmeister

    发明人： David Evans ,  Allison Carley ,  Alison Stewart ,  Michael Higginbottom ,  Edward Savory ,  Iain Simpson ,  Marianne Nilsson ,  Martin Haraldsson ,  Erik Nordling ,  Tobias Koolmeister

    IPC分类号： C07D471/02 ,  A61K31/55 ,  C07D471/04

    CPC分类号： C07D471/04

    摘要： 2-{4-[1-(4-chlorophenyl)-1H-pyrrolo[2,3-c]pyridin-3-yl]piperidin-1-yl}ethan-1-amine; 3-aminopropyl 4-[1-(4-chlorophenyl)-1H-pyrrolo[2,3-c]pyridin-3-yl]piperidine-1-carboxylate; 1-{4-[1-(4-chlorophenyl)-1H-pyrrolo[2,3-c]pyridin-3-yl]piperidin-1-yl}-4-(dimethylamino)butan-1-one; 5-amino-1-{4-[1-(4-chlorophenyl)-1H-pyrrolo[2,3-c]pyridin-3-yl]piperidin-1-yl}pentan-1-one; N-(2-aminoethyl)-4-[1-(4-chlorophenyl)-1H-pyrrolo[2,3-c]pyridin-3-yl]piperidine-1-carboxamide; N-(3-aminopropyl)-4-[1-(4-chlorophenyl)-1H-pyrrolo[2,3-c]pyridin-3-yl]piperidine-1-carboxamide; 4-[1-(4-chlorophenyl)-1H-pyrrolo[2,3-c]pyridin-3-yl]-N-[3-(dimethylamino)propyl]piperidine-1-carboxamide; 1-({4-[1-(4-chlorophenyl)-1H-pyrrolo[2,3-c]pyridin-3-yl]piperidin-1-yl}carbonyl)piperazine; 4-({4-[1-(4-chlorophenyl)-1H-pyrrolo[2,3-c]pyridin-3-yl]piperidin-1-yl}carbonyl)morpholine; 1-({4-[1-(4-chlorophenyl)-1H-pyrrolo[2,3-c]pyridin-3-yl]piperidin-1-yl}carbonyl)-1,4-diazepane; ethyl 1-[1-(4-chlorophenyl)-1H-pyrazolo[3,4-c]pyridin-3-yl]piperidine-4-carboxylate; ethyl 1-[1-(4-methylphenyl)-1H-pyrazolo[3,4-c]pyridin-3-yl]piperidine-4-carboxylate; 1-[1-(4-chlorophenyl)-1H-pyrazolo[3,4-c]pyridin-3-yl]piperidine-4-carboxylic acid; N-(2-aminoethyl)-1-[1-(4-chlorophenyl)-1H-pyrazolo[3,4-c]pyridin-3-yl]piperidine-4-carboxamide; 4-({1-[1-(4-chlorophenyl)-1H-pyrazolo[3,4-c]pyridin-3-yl]piperidin-4yl}carbonyl)morpholine; 1-({1-[1-(4-chlorophenyl)-1H-pyrazolo[3,4-c]pyridin-3-yl]piperidin-4-yl}carbonyl)piperazine; {4-[1-(4-methylphenyl)-1H-pyrazolo[3,4-c]pyridin-3-yl]morpholin-3-yl}methanol; {4-[1-(4-methyl-phenyl)-1H-pyrazolo[3,4-c]pyridin-3-yl]morpholin-2-yl}methanol; [(3R)-4-[1-(4-chlorophenyl)-1H-pyrazolo[3,4-c]pyridin-3-yl]morpholin-3-yl]methanol; methyl 4-[1-(4-chlorophenyl)-1H-pyrazolo[3,4-c]pyridin-3-yl]morpholine-3-carboxylate; N-(2-aminoethyl)-4-[1-(4-chlorophenyl)-1H-pyrazolo[3,4-c]pyridin-3-yl]morpholine-3-carboxamide; 2-{4-[1-(4-chlorophenyl)-1H-pyrazolo[3,4-c]pyridin-3-yl]morpholin-3-yl}ethan-1-ol; methyl 1-[1-(4-chlorophenyl)-1H-pyrazolo[3,4-c]pyridin-3-yl]piperidine-2-carboxylate; N-(2-aminoethyl)-1-[1-(4-chlorophenyl)-1H-pyrazolo[3,4-c]pyridin-3-yl]piperidine-2-carboxamide; 1-({1-[1-(4-chlorophenyl)-1H-pyrazolo[3,4-c]pyridin-3-yl]piperidin-2-yl}carbonyl)piperazine; 4-[1-(4-methylphenyl)-1H-pyrrolo[2,3-c]pyridin-3-yl]morpholine; 1-(4-chlorophenyl)-3-(piperidin-4-yl)-1H-pyrrolo[2,3-c]pyridin-4-ol; N-butyl-1-(4-chlorophenyl)-N-methyl-1H-pyrazolo[3,4-c]pyridin-3-amine; 1-[4-(fluoromethyl)phenyl]-3-(oxan-4-yl)-1H-pyrazolo[3,4-c]pyridine; and 3-({4-[1-(4-chlorophenyl)-1H-pyrazolo[3,4-c]pyridin-3-yl]piperidin-1-yl}methyl)pyridine are useful for the inhibition of SSAO activity.

    Pool Construction Method
    34.
    发明申请
    Pool Construction Method 审中-公开
    池施工方法

    公开(公告)号：US20140304906A1

    公开(公告)日：2014-10-16

    申请号：US13859818

    申请日：2013-04-10

    申请人： Walter Judson Bennett ,  David Evans

    发明人： Walter Judson Bennett ,  David Evans

    IPC分类号： E04H4/14 ,  E02D3/00

    CPC分类号： E02D3/00 ,  E04H4/0037 ,  E04H4/0056 ,  E04H2004/146 ,  Y10T29/49801

    摘要： The present invention relates to a new construction method for swimming pools, surfing pools, body boarding pools, wave pools, water park pools, kayaking and white water rafting courses and pools, wake boarding pools, water skiing pools and jet skiing pools, static surfing simulators, deep water river standing wave attractions. The present invention construction method can also be used in lagoons, ponds, lakes, and rivers. The invention will save construction costs, and save pool construction time.

    摘要翻译： 本发明涉及游泳池，冲浪池，身体游泳池，波浪池，水上公园游泳池，皮划艇和白水漂流课程和游泳池，唤醒游泳池，滑水游泳池和喷气式滑雪游泳池的新的施工方法，静态冲浪 模拟器，深水河站立波浪景点。 本发明的施工方法也可用于泻湖，池塘，湖泊和河流。 本发明可节省施工成本，节约施工时间。

    Method and system for assessing a musical performance
    36.
    发明授权
    Method and system for assessing a musical performance 失效
    用于评估音乐表演的方法和系统

    公开(公告)号：US08367921B2

    公开(公告)日：2013-02-05

    申请号：US11568265

    申请日：2005-01-31

    申请人： David Evans ,  Benjamin Ruciak ,  William Thorpe

    发明人： David Evans ,  Benjamin Ruciak ,  William Thorpe

    IPC分类号： G04B13/00

    CPC分类号： G09B15/00 ,  G09B5/04

    摘要： The invention relates to a method and system for assessing a performance of a musical composition in relation to a model performance of the same composition. In particular, as even a model performance does not follow a score of a composition precisely, the present invention initially correlates the model performance to a score of the performed composition. This allows for an accurate assessment of the timing of the assessable performance, relative to the timing of the model performance. The invention is of particular use where the assessable performance is performed along with the model performance, but the two performances are remote from each other.

    摘要翻译： 本发明涉及一种用于评估与相同构图的模型演奏相关的乐曲的演奏的方法和系统。 特别地，即使模型性能也不能精确地跟随组合得分，本发明最初将模型性能与所执行的组合的得分相关联。 这样可以准确地评估可评估绩效的时间，相对于模型绩效的时间。 本发明在评估性能与模型性能一起执行时具有特别的用途，但两种性能彼此远离。

    Multi-touch detection
    37.
    发明授权
    Multi-touch detection 有权
    多点触摸检测

    公开(公告)号：US08358268B2

    公开(公告)日：2013-01-22

    申请号：US12178415

    申请日：2008-07-23

    申请人： David Evans

    发明人： David Evans

    IPC分类号： G09G5/00

    CPC分类号： G06F3/041 ,  G01S7/003 ,  G01S7/497 ,  G01S15/876 ,  G01S17/87

    摘要： A multi-touch system is provided. The multi-touch system includes a multi-touch detection area generated by a mobile device and a first communication device, the mobile device and first or second communication device being movable relative to each other. The mobile device is operable to determine a first set of coordinates for a first detectable object within the multi-touch detection area as a function of: a distance between the mobile device and the first communication device, a distance between the mobile device and first detectable object, and a distance between the first communication device and first detectable object.

    摘要翻译： 提供多点触控系统。 多点触摸系统包括由移动设备和第一通信设备生成的多点触摸检测区域，移动设备和第一或第二通信设备可相对于彼此移动。 移动设备可操作以根据以下功能确定多点触摸检测区域内的第一可检测对象的第一组坐标：移动设备与第一通信设备之间的距离，移动设备与第一可检测对象之间的距离 物体和第一通信设备与第一可检测对象之间的距离。

    Medical device with elastomeric bulb
    40.
    发明授权
    Medical device with elastomeric bulb 有权
    带弹性球泡的医疗器械

    公开(公告)号：US07875003B2

    公开(公告)日：2011-01-25

    申请号：US11289124

    申请日：2005-11-29

    申请人： Roger Howard Meek ,  David Evans

    发明人： Roger Howard Meek ,  David Evans

    IPC分类号： A61M29/00

    CPC分类号： A61M25/10183 ,  A61M25/0017 ,  A61M25/002 ,  A61M25/10 ,  A61M2039/222 ,  Y10T29/494

    摘要： In a pre-filled Foley catheter for urine drainage, the conventional clip for releasing sterile water from a bulb (21) at the proximal end of the catheter, to fill the anchor bulb (20) at the distal end of the device, is replaced by a plug (25) which has an annular portion connected to a thin stem (27) by a circle of weakness. Snapping the stem (27) from the annulus provides a tactile signal through the opaque latex lumen that the catheter has been actuated. There is no separate clip to be disposed of. The interface between the latex and the plug remains undisturbed. Further improvement in the shelf-life and convenience of use of the catheter is delivered by the use of a sleeve, which can be of shrink-wrap material, around the bulb (21) and optionally also around the drain coupling (15) of the catheter. Apparatus for placing the plug and the sleeve is also described.

    摘要翻译： 在用于排尿的预填充的Foley导管中，用于从导管的近端处的灯泡（21）释放无菌水以填充设备远端处的锚定灯泡（20）的常规夹子被替换 通过具有环形部分的插头（25），所述环形部分通过一个弱点连接到细的杆（27）。 从环形空间中抓住杆（27）通过导管已被致动的不透明胶乳腔提供触觉信号。 没有单独的剪辑被丢弃。 胶乳和塞子之间的界面保持不受干扰。 导管的使用寿命和使用便利性的进一步改进是通过使用可以是包封材料的套筒（其可以是包封材料），并且可选地也围绕灯泡（21）的排水接头（15） 导管。 还描述了用于放置插头和套筒的装置。