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公开(公告)号:US20060195176A1
公开(公告)日:2006-08-31
申请号:US11410354
申请日:2006-04-25
申请人: Brian Bates , Anthony Ragheb , Neal Fearnot , Thomas Kozma , William Voorhees
发明人: Brian Bates , Anthony Ragheb , Neal Fearnot , Thomas Kozma , William Voorhees
IPC分类号: A61F2/82
CPC分类号: A61L33/022 , A61F2/0077 , A61F2/02 , A61F2/06 , A61F2/24 , A61F2/82 , A61F2/91 , A61F2210/0076 , A61F2250/0067 , A61F2250/0068 , A61K51/1282 , A61L27/306 , A61L27/54 , A61L29/085 , A61L29/106 , A61L29/16 , A61L31/088 , A61L31/10 , A61L31/16 , A61L2300/256 , A61L2300/416 , A61L2300/602 , A61L2300/606 , A61L2300/608 , A61L2420/08 , A61N5/1002 , C08L65/04
摘要: Bioactive-coated medical devices are provided, including coated vascular stents. The medical device coating can include a coating layer posited over at least a portion of the medical device surface, and can include a butyl methacrylate polymer or an ethylene-vinyl acetate copolymer in combination with a bioactive material that can function as both an immunosuppressive agent and an antiproliferative agent. Optionally, multilayer coatings can further include an adhesion promoting layer comprising parylene positioned between the coating layer and the medical device surface, a porous layer comprising butyl methacrylate positioned over at least a portion of the coating layer, or both. The coating layer preferably comprises between about 0.5 and 2.0 μg/mm2 of the bioactive material on the outer surface of the medical device. The bioactive material can be absorbed into the coating layer, which can have a thickness of between about 0.5 μm to about 5 μm.
摘要翻译: 提供生物活性涂层医疗器械,包括涂层血管支架。 医疗器械涂层可以包括位于医疗器械表面的至少一部分上的涂层,并且可以包括甲基丙烯酸丁酯聚合物或乙烯 - 乙酸乙烯酯共聚物与可以用作免疫抑制剂和生物活性物质的生物活性材料 抗增生剂。 任选地,多层涂层还可以包括粘合促进层,其包括定位在涂层和医疗器件表面之间的聚对二甲苯,包含位于涂层的至少一部分上的甲基丙烯酸丁酯的多孔层,或两者。 涂层优选包含在医疗装置的外表面上的生物活性材料的约0.5和2.0杯/平方毫米之间。 生物活性材料可以被吸收到涂层中,其可以具有在约0.5μm至约5μm之间的厚度。
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公开(公告)号:US20060020331A1
公开(公告)日:2006-01-26
申请号:US11234702
申请日:2005-09-23
申请人: Brian Bates , Scott Boatman , David Burton , Michael Hoffa , Darin Schaeffer , Jason Sturgeon , Anthony Ragheb
发明人: Brian Bates , Scott Boatman , David Burton , Michael Hoffa , Darin Schaeffer , Jason Sturgeon , Anthony Ragheb
IPC分类号: A61F2/06
CPC分类号: A61M25/10 , A61F2/82 , A61F2/844 , A61F2/86 , A61F2/958 , A61F2210/0014 , A61F2210/0076 , A61F2240/001 , A61F2250/0025 , A61F2250/0026 , A61F2250/0067 , A61F2250/0081 , A61F2250/0098 , A61F2310/00011 , A61L27/54 , A61L29/08 , A61L29/085 , A61L29/16 , A61L29/18 , A61L31/14 , A61L31/16 , A61L2300/416 , A61L2300/606 , A61L2400/18 , A61L2420/02 , A61L2420/06 , A61M25/1029 , A61M25/104 , A61M2025/1031 , A61M2025/105 , A61M2250/00
摘要: A coated medical device adapted for introduction into a passage or vessel of a patient is provided. The medical device is preferably an implantable balloon with a bioactive deposited or within the balloon. The balloon can further include a hydrophilic material positioned between the balloon and a bioactive material posited on the balloon.
摘要翻译: 提供适于引入患者的通道或容器中的涂覆医疗装置。 医疗装置优选地是具有生物活性沉积的或在球囊内的可植入气球。 球囊可以进一步包括位于球囊和放置在球囊上的生物活性物质之间的亲水材料。
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公开(公告)号:US20050267560A1
公开(公告)日:2005-12-01
申请号:US11136039
申请日:2005-05-23
申请人: Brian Bates
发明人: Brian Bates
CPC分类号: A61F2/2475 , A61F2/2418 , A61F2210/0004 , A61F2220/0016 , A61F2220/0075 , A61F2230/0023 , A61F2230/0026 , A61F2230/0054 , A61F2230/0078 , A61F2230/008 , A61F2230/0095
摘要: Medical devices for implantation within a body vessel comprising a frame formed at least in part from a metallic bioabsorbable material are provided. The devices can be pushed from a delivery catheter into the lumen of a duct or vessel and may include one or more barbs for anchoring purposes. A full or partial covering of fabric or other flexible material, or a bioabsorbable material, including a collagen-based material such as small intestinal submucosa (SIS), may be attached to the frame to form an occlusion device, a graft, or an implantable, intraluminal valve such as for correcting incompetent venous valves.
摘要翻译: 提供用于植入体内容器的医疗装置,其包括至少部分地由金属生物可吸收材料形成的框架。 装置可以从输送导管推入管道或容器的内腔中,并且可以包括用于锚定目的的一个或多个倒钩。 织物或其他柔性材料或包括基于胶原的材料如小肠粘膜下层(SIS)的生物可吸收材料的全部或部分覆盖物可以附接到框架上以形成闭塞装置,移植物或植入物 ,腔内瓣膜如纠正无力静脉瓣膜。
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公开(公告)号:US20050222677A1
公开(公告)日:2005-10-06
申请号:US11137275
申请日:2005-05-25
申请人: Brian Bates , Anthony Ragheb , Neil Fearnot , Thomas Kozma , William Voorhees
发明人: Brian Bates , Anthony Ragheb , Neil Fearnot , Thomas Kozma , William Voorhees
IPC分类号: A61F2/00 , A61F2/02 , A61F2/06 , A61F2/24 , A61F2/82 , A61K51/12 , A61L27/30 , A61L27/54 , A61L29/08 , A61L29/10 , A61L29/16 , A61L31/08 , A61L31/10 , A61L31/16 , A61L33/02 , A61N5/10
CPC分类号: A61L33/022 , A61F2/0077 , A61F2/02 , A61F2/06 , A61F2/24 , A61F2/82 , A61F2/91 , A61F2210/0076 , A61F2250/0067 , A61F2250/0068 , A61K51/1282 , A61L27/306 , A61L27/54 , A61L29/085 , A61L29/106 , A61L29/16 , A61L31/088 , A61L31/10 , A61L31/16 , A61L2300/256 , A61L2300/416 , A61L2300/602 , A61L2300/606 , A61L2300/608 , A61L2420/08 , A61N5/1002 , C08L65/04
摘要: A coated implantable medical device 10 includes a structure 12 adapted for introduction into the vascular system, esophagus, trachea, colon, biliary tract, or urinary tract; at least one coating layer 16 posited on one surface of the structure; and at least one layer 18 of a bioactive material posited on at least a portion of the coating layer 16, wherein the coating layer 16 provides for the controlled release of the bioactive material from the coating layer. In addition, at least one porous layer 20 can be posited over the bioactive material layer 18, wherein the porous layer includes a polymer and provides for the controlled release of the bioactive material therethrough. Preferably, the structure 12 is a coronary stent. The porous layer 20 includes a polymer applied preferably by vapor or plasma deposition and provides for a controlled release of the bioactive material. It is particularly preferred that the polymer is a polyamide, parylene or a parylene derivative, which is deposited without solvents, heat or catalysts, and merely by condensation of a monomer vapor.
摘要翻译: 涂覆的可植入医疗装置10包括适于引入到血管系统,食道,气管,结肠,胆道或尿道中的结构12; 至少一个涂层16位于该结构的一个表面上; 和至少一层生物活性物质的层18位于涂层16的至少一部分上,其中涂层16提供生物活性材料从涂层的受控释放。 此外,至少一个多孔层20可以放置在生物活性材料层18上方,其中多孔层包括聚合物并提供生物活性材料通过其控制释放。 优选地,结构12是冠状动脉支架。 多孔层20包括优选通过蒸气或等离子体沉积施加的聚合物,并提供生物活性材料的受控释放。 特别优选的是,聚合物是聚酰胺,聚对二甲苯或聚对二甲苯衍生物,它们不经溶剂,热或催化剂沉积,并且仅通过单体蒸气的冷凝而沉积。
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公开(公告)号:US20210019693A1
公开(公告)日:2021-01-21
申请号:US16510981
申请日:2019-07-15
申请人: Steve Gu , Stuart Kyle Neubarth , Ying Zheng , Brian Bates
发明人: Steve Gu , Stuart Kyle Neubarth , Ying Zheng , Brian Bates
IPC分类号: G06Q10/08 , A47F13/00 , A47F5/08 , G06T7/292 , H04N5/232 , H04N5/247 , G01P13/00 , G01G19/14 , G01G19/52
摘要: The present invention describes a system for monitoring items coupled with support utilities. The system is configured to detect motions caused by customer actions and optimize the camera system and computing resources of a remote server. The system also is configured to sense items that are removed, added or misplaced automatically.
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公开(公告)号:US20210017664A1
公开(公告)日:2021-01-21
申请号:US16933387
申请日:2020-07-20
申请人: Ying Zhang , Brian Bates , Jason Witman
发明人: Ying Zhang , Brian Bates , Jason Witman
摘要: An apparatus is disclosed for applying a coating to a desired object including a rotatable container having at least one container wall. An electrolyte can be retained within the container, the at least one container wall made of a material that does not allow the electrolyte to pass through the at least one container wall of the container. An anode can be positioned within the container. The apparatus can include a mount for securing the desired object such that a surface of the desired object is exposed to the electrolyte. A controller can be in electrical communication with the anode and the mount, wherein when power is supplied from the controller to the anode and the mount, particles in the electrolyte are deposited on the desired object forming a composite coating.
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公开(公告)号:US08871093B2
公开(公告)日:2014-10-28
申请号:US13349185
申请日:2012-01-12
申请人: Christopher J. Ball , Brian Bates
发明人: Christopher J. Ball , Brian Bates
CPC分类号: B01D24/22 , B01D24/24 , B01D24/4631 , G06Q50/22 , H04N7/18
摘要: A filter system for filtering a liquid containing particles including a single media retainer plate having a top and bottom surface, and defining at least one hopper-shaped compartment having a sloped wall defining a slot spanning the top and bottom surfaces is disclosed. The plate also includes at least one baffle extending from the bottom surface and filter media disposed on the top surface. During a filtering operation of the filter system, the filter media captures the particles, such as dirt, from the liquid as the liquid passes through the filter media to an underdrain system. During a backwash operation of the filter system, the baffle is adapted to direct a backwash fluid in a vertical direction through the slot so that the backwash fluid actuates the filter media to scour the top surface of the plate and prevent the build-up of biological scaling on the plate.
摘要翻译: 公开了一种过滤系统,用于过滤含有颗粒的液体,包括具有顶部和底部表面的单个介质保持板,并且限定了至少一个具有限定跨越顶部和底部表面的槽的倾斜壁的料斗形隔室。 板还包括从底表面延伸的至少一个挡板和设置在顶表面上的过滤介质。 在过滤系统的过滤操作期间,当液体通过过滤介质时,过滤介质从液体中捕获诸如污物的颗粒,从而将液体通过过滤介质。 在过滤系统的回洗操作期间,挡板适于将反洗流体沿垂直方向引导通过狭槽,使得反冲洗流体致动过滤介质以冲洗板的顶表面并防止生物体的积聚 在板上缩放。
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公开(公告)号:US20110071914A1
公开(公告)日:2011-03-24
申请号:US12564356
申请日:2009-09-22
申请人: Garland B. Beasley , Charles Jarrett , Alan Anderson , Jay Jacobson , Raymond Dalton , Brian Bates
发明人: Garland B. Beasley , Charles Jarrett , Alan Anderson , Jay Jacobson , Raymond Dalton , Brian Bates
CPC分类号: G06Q20/40 , G06Q20/105 , G06Q20/202 , G06Q20/32 , G06Q20/3223 , G06Q20/385 , G06Q40/02 , G06Q40/08
摘要: Methods and apparatuses for secure transaction management are provided. An example method may include verifying that a mobile terminal identifier is registered with an account, generating an authorization code, and verifying that the received authorization code matches the authorization code stored in association with the account, and the received customer verification number matches the customer verification number associated with the account. The example method may also include providing for transmission of a verification reply to authorize the transaction.
摘要翻译: 提供了用于安全事务管理的方法和装置。 示例性方法可以包括验证移动终端标识符是否被注册到帐户,生成授权码,以及验证所接收到的授权码是否与存储在帐户中的授权码相匹配,并且所接收的客户验证号与客户验证匹配 与帐户相关联的号码。 示例性方法还可以包括提供验证回复的传输以授权交易。
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公开(公告)号:US20070168012A1
公开(公告)日:2007-07-19
申请号:US11604539
申请日:2006-11-27
申请人: Anthony Ragheb , Brian Bates , Neal Fearnot , Thomas Kozma , William Voorhees
发明人: Anthony Ragheb , Brian Bates , Neal Fearnot , Thomas Kozma , William Voorhees
IPC分类号: A61F2/06
CPC分类号: A61K51/1282 , A61F2/24 , A61F2/82 , A61F2250/0068 , A61L27/306 , A61L27/54 , A61L29/085 , A61L29/106 , A61L29/16 , A61L31/088 , A61L31/10 , A61L31/16 , A61L33/022 , A61L2300/256 , A61L2300/416 , A61L2300/602 , A61L2300/606 , A61L2300/608 , A61L2420/08 , A61N5/1002 , C08L65/04
摘要: Methods of making coated implantable medical devices are provided. The methods include positioning a first layer comprising a bioactive on at least a portion of a structure, and positioning at least one porous layer over the first layer. The at least one porous layer has a thickness adequate to provide a controlled release of the bioactive.
摘要翻译: 提供涂覆的可植入医疗装置的方法。 所述方法包括将包含生物活性的第一层定位在结构的至少一部分上,并将至少一个多孔层定位在第一层之上。 至少一个多孔层具有足以提供生物活性的受控释放的厚度。
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公开(公告)号:US20070095345A1
公开(公告)日:2007-05-03
申请号:US11567613
申请日:2006-12-06
申请人: Richard Dalgetty , Brian Bates , Michael Nelson
发明人: Richard Dalgetty , Brian Bates , Michael Nelson
IPC分类号: A61M15/00
CPC分类号: A22B3/005 , A01K1/031 , A22B3/00 , A61D7/04 , A61M16/104 , A61M16/18 , A61M16/202 , A61M16/209 , A61M2016/0039
摘要: The present invention provides improved anesthesia delivery systems that consistently and reliably deliver anesthesia gas to multiple gas outlets. The systems are particularly useful for anesthetizing multiple mammals and living specimens to be imaged by a low-light level imaging system. The anesthesia delivery systems are suitable for use with conventional oxygen sources, and convert the high pressures associated with a conventional oxygen source to lower pressures suitable for use with small mammals and suitable for combination with an anesthesia gas at low flow rates. The systems include an anesthesia gas source that combines anesthesia gas with the oxygen. The combination of anesthesia gas and oxygen is supplied to one or more multiple outlets.
摘要翻译: 本发明提供了改进的麻醉输送系统,其一致地且可靠地将麻醉气体输送到多个气体出口。 该系统对于通过低光级成像系统麻醉多个哺乳动物和要被成像的活体样品特别有用。 麻醉输送系统适用于常规氧源,并将与常规氧源相关联的高压转化为适合与小型哺乳动物一起使用的较低压力,并且适合于与低流量下的麻醉气体组合。 该系统包括将麻醉气体与氧气组合的麻醉气体源。 麻醉气体和氧气的组合被提供给一个或多个多个出口。
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