公开(公告)号：US20240277473A1

公开(公告)日：2024-08-22

申请号：US18645284

申请日：2024-04-24

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： Michael Bukin ,  Nikolai Gurovich ,  Anatoly Dvorsky ,  Eran Grosu ,  Noam Nir ,  Joseph Mordechai Leichner

IPC: A61F2/24

CPC classification number: A61F2/243 ,  A61F2/2418 ,  A61F2250/001

Abstract: A prosthetic device, such as a prosthetic heart valve, can include a radially compressible and expandable frame and a screw actuator that is coupled to the frame and configured to be rotated to radially expand the frame from a radially compressed state to a first radially expanded state. The frame includes an over-expansion structure that is configured to allow relative sliding movement between the screw actuator and the frame in a longitudinal direction to permit the frame to radially expand from the first radially expanded state to a second radially expanded state when an external expansion force applied to the prosthetic heart valve exceeds a predetermined force.

公开(公告)号：US20230355387A1

公开(公告)日：2023-11-09

申请号：US18355367

申请日：2023-07-19

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： Anatoly Dvorsky

IPC: A61F2/24

CPC classification number: A61F2/243 ,  A61F2250/0048

Abstract: A docking device can include a radially expandable and compressible frame and an actuator. The frame can include a first sub-frame having a first plurality of struts pivotably coupled to one another, a second sub-frame having a second plurality of struts pivotably coupled to one another, and one or more linking struts extending from a first end of the frame to a second end of the frame and coupling the first sub-frame and the second sub-frame to one another. The actuator can include a first member coupled to the frame at a first location and a second member coupled to the frame at a second location axially spaced from the first location. The actuator can be used to mechanically expand the docking device.

公开(公告)号：US20230285144A1

公开(公告)日：2023-09-14

申请号：US18015707

申请日：2021-07-08

Applicant: Edwards Lifesciences Corporation

Inventor： Haim Yushtein ,  Anatoly Dvorsky ,  David Maimon ,  Noam Nir ,  Alon Ben-Yosef

IPC: A61F2/24

CPC classification number: A61F2/2418 ,  A61F2/243 ,  A61F2/2439 ,  A61F2220/0091 ,  A61F2250/001 ,  A61F2250/0029

Abstract: A prosthetic device, such as a prosthetic heart valve, can include a frame that is radially expandable and compressible between a radially compressed state and a radially expanded state. In some examples, the prosthetic device can include locking mechanisms that are configured to hold the prosthetic device in a radially expanded state. In some examples, the locking mechanisms can be integrated into the frame of the prosthetic device.

公开(公告)号：US20230255752A1

公开(公告)日：2023-08-17

申请号：US18136944

申请日：2023-04-20

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： Joseph Mordechai Leichner ,  Anatoly Dvorsky ,  Michal Aliza Ruchelsman

IPC: A61F2/24 ,  A61F2/95

CPC classification number: A61F2/24 ,  A61F2/9517 ,  A61F2220/0025

Abstract: The present invention relates to systems, assemblies and methods for estimating prosthetic valve expansion diameter, and in particular, for system and assemblies equipped with at least one sound or vibration sensor configured to provide real-time estimate of prosthetic valve expansion diameter.

公开(公告)号：US20220257367A1

公开(公告)日：2022-08-18

申请号：US17732985

申请日：2022-04-29

Applicant: Edwards Lifesciences Corporation

Inventor： Yair A. Neumann ,  Oren Cohen ,  Khen Perlmutter ,  Eitan Atias ,  Noam Miller ,  Eran Goldberg ,  Anatoly Dvorsky ,  Tamir S. Levi ,  Haim Yushtein ,  Danny M. Garmahi ,  Ziv Yohanan ,  Michael Bukin ,  Noam Nir ,  Elena Sherman ,  Gideon Sagi

IPC: A61F2/24

Abstract: An implantable prosthetic valve can include a frame movable between a radially compressed and a radially expanded configuration. The frame can include a first strut having a first locking feature disposed on a radially facing inner surface of the strut and a second strut having a second locking feature disposed on a radially facing outer surface of the strut. The first and second locking features can engage each other so as to allow pivoting of the first and second struts relative to one another in a first direction upon radial expansion of the frame and resist pivoting of the first and second struts relative to one another in a second direction to resist radial compression of the frame.

公开(公告)号：US20250064584A1

公开(公告)日：2025-02-27

申请号：US18942285

申请日：2024-11-08

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： Michael Bukin ,  Nikolai Gurovich ,  Elena Sherman ,  Anatoly Dvorsky ,  Giolnara Pinhas

IPC: A61F2/24

Abstract: A prosthetic heart valve can include a radially expandable and compressible annular frame, a valvular structure, and a commissure cover. The frame can include a plurality of struts defining the annular frame, and a plurality of commissure support structures each defining a commissure opening positioned along a circumference of the annular frame. The valvular structure can be mounted within the frame, the valvular structure including a plurality of commissures each extending radially through a respective commissure opening to attach the valvular structure to the frame, each commissure having an outflow edge that extends from a radial outer surface of the frame. The commissure cover can be disposed at least partially over the outflow edge of the commissure and can define a ramped surface that extends from the radial outer surface of the frame to a radial outer surface of the commissure.

公开(公告)号：US20240374384A1

公开(公告)日：2024-11-14

申请号：US18780203

申请日：2024-07-22

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： Anatoly Dvorsky ,  Nikolai Gurovich ,  Michael Bukin ,  Eran Grosu

IPC: A61F2/24

Abstract: A prosthetic heart valve can include a radially expandable and compressible frame and a valvular structure. The frame can include a plurality of circumferentially spaced axial struts, a plurality of pairs of axial posts, and a plurality of rows of angled struts. Each pair of axial posts can be positioned circumferentially between two axial struts. The plurality of rows can include at least a first row, a second row downstream of the first row, a third row downstream of the second row, and a fourth row downstream of the third row. Each of the angled struts can be connected at one end to one of the axial struts and at another end to one of the axial posts. The angled struts of the first and fourth rows can be shorter than the struts of the second and third rows.

公开(公告)号：US20240366367A1

公开(公告)日：2024-11-07

申请号：US18772519

申请日：2024-07-15

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： Anatoly Dvorsky ,  Alon Ben-Yosef ,  Eran Grosu ,  Nikolai Gurovich ,  Michael Bukin ,  Ilan Leshecz ,  Joseph Mordechai Leichner

IPC: A61F2/24

Abstract: This disclosure is directed to prosthetic heart valves and frames for prosthetic heart valves having actuation assemblies with at least two bolts coupled to each other. The actuation assembly with at least two bolts allow different portions of the actuation assembly to be designed to meet different needs. In one example, the actuation mechanism can include a first bolt coupled end-to-end with a second bolt. The second bolt can have a greater diameter and correspondingly greater mechanical strength than the first bolt. The first bolt can have a lesser diameter suitable for minimizing the thickness of surrounding and adjacent valve frame components. The actuation assembly can also include one or more of a nut, a washer, and a portion designed to attach to components of a delivery system. Also disclosed herein are actuation assemblies including a washer secured by a pin extending through the bolt of the actuation assembly.

公开(公告)号：US12083012B2

公开(公告)日：2024-09-10

申请号：US17824411

申请日：2022-05-25

Applicant: Edwards Lifesciences Corporation

Inventor： David Maimon ,  Boaz Manash ,  Eyal Leiba ,  Ziv Yohanan ,  Yair A. Neumann ,  Anatoly Dvorsky ,  Jonathan Bar-Or ,  Oren Cohen ,  Ofir Witzman ,  Liron Tayeb ,  Elazar Levi Schwarcz ,  Noam Miller ,  Tomer Saar

IPC: A61F2/24

CPC classification number: A61F2/2418 ,  A61F2/243 ,  A61F2220/0041 ,  A61F2250/001 ,  A61F2250/0069

Abstract: An assembly can comprise a prosthetic valve comprising a radially expandable and compressible frame and a rotatable screw connected to the frame, where the screw comprises a screw head having an annular bore with internal threads, and where the screw is rotatable to radially expand the frame. The assembly further comprises a delivery apparatus releasably coupled to the screw, the delivery apparatus comprising a first shaft and a first head disposed at an end of the first shaft, the first head comprising external threads configured to engage with the internal threads of the screw head, and a second shaft that is coaxial with and surrounds the first shaft, the second shaft comprising a second head disposed at an end of the second shaft. The second head is configured to releasably engage with an exterior surface of the screw head and rotate the screw.

公开(公告)号：US20240189100A1

公开(公告)日：2024-06-13

申请号：US18582897

申请日：2024-02-21

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： David Maimon ,  Boaz Manash ,  Eyal Leiba ,  Ziv Yohanan ,  Yair A. Neumann ,  Anatoly Dvorsky ,  Jonathan Bar-Or ,  Oren Cohen ,  Ofir Witzman ,  Liron Tayeb ,  Elazar Levi Schwarcz ,  Noam Miller ,  Tomer Saar

IPC: A61F2/24

CPC classification number: A61F2/2418 ,  A61F2/243 ,  A61F2220/0041 ,  A61F2250/001 ,  A61F2250/0069

Abstract: A method can comprise deploying a prosthetic valve with a delivery apparatus, where the prosthetic valve comprises a frame and a rotatable screw connected to the frame, and where the screw comprises a screw head having an annular bore with internal threads. The delivery apparatus is releasably coupled to the screw and can comprise a first shaft and a first head disposed at an end of the first shaft, the first head comprising external threads releasably engaged with the internal threads of the screw head, and a second shaft that is coaxial with and surrounds the first shaft, the second shaft comprising a second head disposed at an end of the second shaft, the second head releasably engaged with an exterior surface of the screw head. Deploying the valve includes radially expanding the prosthetic valve by rotating the screw with the delivery apparatus.