公开(公告)号：US08764638B2

公开(公告)日：2014-07-01

申请号：US12587905

申请日：2009-10-15

申请人： John Schwartz ,  Richard Schwartz ,  Harsha Setty

发明人： John Schwartz ,  Richard Schwartz ,  Harsha Setty

IPC分类号： A61B1/005 ,  A61B1/267

CPC分类号： A61M16/0488 ,  A61B1/00048 ,  A61B1/00052 ,  A61B1/00066 ,  A61B1/00124 ,  A61B1/00137 ,  A61B1/053 ,  A61B1/0684 ,  A61B1/267 ,  A61M25/0136 ,  A61M25/0147

摘要： A detachable stylet assembly for endotracheal intubation of a patient is disclosed. The stylet comprises an elongated tube defining: a longitudinal axis, a proximal end for detachably mounting the stylet to a hand grip, and a distal end for entering the trachea of the patient. The tube comprises an articulation section adjacent the distal end adapted to curve into the trachea upon actuation. An actuator housing is mounted on and adjacent to the proximal end of the tube. An actuating assembly is constructed inside the actuator housing having connection means for engaging the hand grip. A control wire is mounted within the actuator housing and connected to the actuating assembly. The control wire extends through the tube to the distal end of the tube and is adapted to curve the articulation section upon actuation. The hand grip comprises a base handle and a trigger for manual actuation of the actuator assembly. The trigger comprises finger grooves for convenient gripping. The base handle comprises a hand stop to prevent slippage.

摘要翻译： 公开了一种用于患者的气管插管的可拆卸探针组件。 探针包括细长管，其限定：纵向轴线，用于将探针可拆卸地安装到手柄的近端，以及用于进入患者气管的远端。 该管包括邻近远端的铰接部分，适于在致动时弯曲成气管。 致动器壳体安装在管的近端上并且靠近管的近端。 致动组件构造在致动器壳体内部，具有用于接合手柄的连接装置。 控制线安装在致动器壳体内并连接到致动组件。 控制线通过管延伸到管的远端，并且适于在致动时使关节部弯曲。 手柄包括基部手柄和用于手动致动致动器组件的触发器。 触发器包括用于方便抓握的指槽。 底座手柄包括防止滑动的手停。

公开(公告)号：US20120078050A1

公开(公告)日：2012-03-29

申请号：US12924358

申请日：2010-09-24

申请人： John Schwartz ,  Richard Schwartz ,  Harsha Setty

发明人： John Schwartz ,  Richard Schwartz ,  Harsha Setty

IPC分类号： A61B1/06 ,  A61B1/267 ,  A61M16/04

CPC分类号： A61B1/00052 ,  A61B1/00105 ,  A61B1/0051 ,  A61B1/0052 ,  A61B1/0057 ,  A61B1/05 ,  A61B1/267 ,  A61B1/2673 ,  A61B1/2676 ,  A61M16/0488 ,  A61M25/0136 ,  A61M25/04

摘要： A stylet assembly for performing a nasal endotracheal intubation of a patient is disclosed. The stylet assembly includes an elongated tube as a stylet for the intubation defining a longitudinal axis, a proximal end, and a distal end for entering the trachea of the patient. The elongated tube includes (i) a rigid section adjacent the proximal end, (ii) an articulation section adjacent the distal end and adapted to curve into the patient's trachea upon actuation, and (iii) a flexible section between the rigid section and the articulation section, the flexible section being adapted to curve to an internal shape of at least one of the patient's nose, nasal cavity, pharynx, and larynx during nasal intubation. The stylet assembly can further include an actuator housing, a control wire for actuating the articulating section, and a hand grip for maneuvering the stylet assembly.

摘要翻译： 公开了一种用于进行患者鼻气管插管的探针组件。 探针组件包括细长管作为插管的探针，其限定纵向轴线，近端和用于进入患者气管的远端。 细长管包括（i）邻近近端的刚性部分，（ii）邻近远端并且适于在致动时弯曲到患者气管中的关节部分，以及（iii）刚性部分和关节之间的柔性部分 在鼻插管期间，柔性部分适于弯曲至患者鼻部，鼻腔，咽和喉部中的至少一个的内部形状。 探针组件还可包括致动器壳体，用于致动铰接部分的控制线以及用于操纵探针组件的手柄。

公开(公告)号：US08119388B2

公开(公告)日：2012-02-21

申请号：US12686926

申请日：2010-01-13

申请人： Richard Schwartz ,  John Michael Berry ,  Ajit Subramanian ,  Xiao Shi

发明人： Richard Schwartz ,  John Michael Berry ,  Ajit Subramanian ,  Xiao Shi

IPC分类号： C12N7/04

CPC分类号： C12N7/00 ,  C12N5/0037 ,  C12N5/0043 ,  C12N2500/36 ,  C12N2500/76 ,  C12N2500/90 ,  C12N2501/11 ,  C12N2501/395 ,  C12N2510/02 ,  C12N2760/16151 ,  C12N2760/16161 ,  C12N2760/16251 ,  C12N2760/16261

摘要： The present invention provides novel MDCK-derived adherent non-tumorigenic cell lines that can be grown in the presence or absence of serum. The cell lines of the present invention are useful for the production of vaccine material (e.g., viruses). More specifically, the cell lines of the present invention are useful for the production of influenza viruses in general and ca/ts influenza viruses in particular. The invention further provides methods and media formulations for the adaptation and cultivation of MDCK cells such that they remain non-tumorigenic. Additionally, the present invention provides methods for the production of vaccine material (e.g., influenza virus) in the novel cell lines of the invention.

摘要翻译： 本发明提供可在血清存在或不存在的情况下生长的新型MDCK衍生的粘附性非致瘤细胞系。 本发明的细胞系可用于生产疫苗材料（例如病毒）。 更具体地说，本发明的细胞系通常用于生产流感病毒，尤其是流感病毒。 本发明还提供了用于适应和培养MDCK细胞的方法和培养基制剂，使得它们保持非致瘤性。 此外，本发明提供了在本发明的新型细胞系中生产疫苗材料（例如流感病毒）的方法。

公开(公告)号：US20120005360A1

公开(公告)日：2012-01-05

申请号：US12829145

申请日：2010-07-01

申请人： Gordon Yong Li ,  Xuemin Chen ,  John McQueen ,  Sam Anderson ,  Pierre Couilaud ,  Richard Schwartz

发明人： Gordon Yong Li ,  Xuemin Chen ,  John McQueen ,  Sam Anderson ,  Pierre Couilaud ,  Richard Schwartz

IPC分类号： G06F15/16

CPC分类号： H04L41/0813 ,  H04L12/281 ,  H04L12/2834 ,  H04L12/2898 ,  H04L41/0816 ,  H04L65/1026 ,  H04L65/605

摘要： A common IP layer client device interface within an IP multimedia gateway (IMG) is configured to connect client devices to broadband IP networks such as the Internet based on determined device capabilities. Broadband IP network interfaces within the IMG are configured to enable communication between the IMG and broadband IP networks based on the determined device capabilities. Content provided by various service managers are communicated with the client devices utilizing the common IP layer client device interface and the configured network interfaces. Network capabilities may be determined during the device and network discovery. Protocol translation, media transcoding and/or dynamic device configuration may be performed based on the determined device capabilities, and based on the determined network capabilities. The IMG may adjust system timing and manage power consumptions for service deployment over corresponding client devices. Information may be routed or distributed by the IMRG among the client devices when needed.

摘要翻译： IP多媒体网关（IMG）中的公共IP层客户端设备接口被配置为基于确定的设备能力将客户端设备连接到诸如因特网的宽带IP网络。 IMG中的宽带IP网络接口被配置为基于所确定的设备能力来实现IMG和宽带IP网络之间的通信。 使用公共IP层客户端设备接口和配置的网络接口，与客户端设备通信各种服务管理器提供的内容。 可以在设备和网络发现期间确定网络功能。 可以基于所确定的设备能力，并且基于所确定的网络能力来执行协议转换，媒体代码转换和/或动态设备配置。 IMG可以通过相应的客户端设备调整系统时间并管理服务部署的功耗。 当需要时，信息可以由客户端设备中的IMRG进行路由或分发。

公开(公告)号：US07715393B2

公开(公告)日：2010-05-11

申请号：US10448028

申请日：2003-05-30

申请人： David M Pullen ,  Richard Schwartz ,  Kevin E O'Neal ,  John McQueen

发明人： David M Pullen ,  Richard Schwartz ,  Kevin E O'Neal ,  John McQueen

IPC分类号： H04L12/28

CPC分类号： H04L47/2433 ,  H04L12/2801 ,  H04L47/10 ,  H04L47/15 ,  H04L47/32 ,  H04L47/50 ,  H04L47/625 ,  H04L49/90

摘要： A system and method for processing information transport elements, such as ethernet packets, at interfaces to a forwarder. Modules that implement processing logic are allocated per interface and per direction (i.e., inbound or outbound). At any given interface, a series of modules would be used to process inbound packets; likewise, a set of modules would be used to process outbound packets. For inbound packets, the modules allocated for inbound processing are executed when the packet is received from the interface, before sending the packet on to the forwarder. For packets that are outbound from the forwarder, the modules allocated for outbound processing are applied when the packet is sent by the forwarder, prior to any other processing, e.g., queuing to hardware. To assign modules to different interfaces at a forwarder, a registration process is performed during the system start-up process, or dynamically at runtime. For any given interface and direction, modules can be prioritized, so that a packet is processed sequentially in a specific order, one module after the other.

摘要翻译： 一种用于在与转发器的接口处理诸如以太网分组之类的信息传输元件的系统和方法。 根据接口和每个方向（即入站或出站）分配实现处理逻辑的模块。 在任何给定的接口，一系列模块将用于处理入站数据包; 同样，一组模块将用于处理出站数据包。 对于入站数据包，在将数据包发送到转发器之前，从接口接收到数据包时，执行分配用于入站处理的模块。 对于从转发器出站的数据包，在进行任何其他处理（例如排队到硬件）之前，当转发器发送数据包时，分配用于出站处理的模块被应用。 要在转发器处将模块分配给不同的接口，在系统启动过程中或在运行时动态执行注册过程。 对于任何给定的接口和方向，可以对模块进行优先级排序，以便以特定顺序顺序处理数据包，一个接一个地进行处理。

公开(公告)号：US20090285198A1

公开(公告)日：2009-11-19

申请号：US12119627

申请日：2008-05-13

申请人： Richard Schwartz ,  Ray Farhat

发明人： Richard Schwartz ,  Ray Farhat

IPC分类号： H04L12/66

CPC分类号： H04L12/66

摘要： A method for supporting communication between a source internet protocol phone and a destination internet protocol phone is provided. The source internet protocol phone communicates via a Network Address Translator (“NAT”) gateway. The method includes receiving a packet from the source phone at the NAT. The packet is for communication with the destination phone. The method further includes querying whether the destination phone is located in the subnetwork serviced by the NAT gateway. If the destination phone is not located in the subnetwork serviced by the NAT gateway, then the method includes sending the packet upstream to the destination phone via the Internet. If the destination phone is located in the subnetwork serviced by the NAT gateway, then the method includes directing the packet to the destination phone.

摘要翻译： 提供一种用于支持源互联网协议电话和目的地互联网协议电话之间的通信的方法。 源互联网协议电话通过网络地址转换器（“NAT”）网关进行通信。 该方法包括在NAT处从源电话接收分组。 该分组用于与目的地电话通信。 该方法还包括查询目的地电话是否位于由NAT网关服务的子网中。 如果目的地电话没有位于由NAT网关服务的子网中，则该方法包括经由因特网将分组向上游发送到目的地电话。 如果目的地电话位于由NAT网关服务的子网中，则该方法包括将分组指向目的地电话。

公开(公告)号：USD603959S1

公开(公告)日：2009-11-10

申请号：US29312315

申请日：2008-10-14

申请人： John Schwartz ,  Richard Schwartz ,  Harsha Setty

设计人： John Schwartz ,  Richard Schwartz ,  Harsha Setty

公开(公告)号：US20090208532A1

公开(公告)日：2009-08-20

申请号：US12370110

申请日：2009-02-12

申请人： Qi Dang ,  Richard Schwartz

发明人： Qi Dang ,  Richard Schwartz

IPC分类号： A61K39/145 ,  C12N7/02

CPC分类号： C12N7/00 ,  A61K39/12 ,  A61K39/145 ,  C12N2760/16211 ,  C12N2760/16234 ,  C12N2760/16261

摘要： Methods and compositions for the optimization and production of influenza viruses, e.g., ca influenza B strains, in eggs and host cells suitable as influenza vaccines are provided.

摘要翻译： 提供了用于优化和生产适合作为流感疫苗的鸡蛋和宿主细胞中的流感病毒例如流感乙型流感病毒株的方法和组合物。

公开(公告)号：US20090090357A1

公开(公告)日：2009-04-09

申请号：US11906870

申请日：2007-10-04

申请人： John Schwartz ,  Richard Schwartz

发明人： John Schwartz ,  Richard Schwartz

IPC分类号： A61M16/00

CPC分类号： A61M16/0488

摘要： The present disclosure provides for a guide adapted for facilitating insertion of a medical device into the trachea of a patient. The guide comprises an integral curved-shaped member having at least a first leg at one end of the guide. The curved-shaped member consists essentially of an outside curved side defining a concave groove. A first angle is defined on the first leg configured and dimensioned to allow for at least the first leg to pass through the mouth and into the trachea of the patient. Insertion of the guide into the trachea allows for elevation of the tongue and surrounding soft tissue of the patient thereby forming an air space that allows for passage of a medical device.

摘要翻译： 本公开提供了适于便于将医疗装置插入患者的气管中的引导件。 引导件包括整体的弯曲形状的构件，其在引导件的一端具有至少一个第一腿部。 曲形构件基本上由限定凹槽的外侧弯曲侧构成。 第一个角度被限定在第一腿上，其构造和尺寸被设计成允许至少第一腿部通过口并进入患者的气管。 引导件插入气管允许患者的舌头和周围的软组织升高，从而形成允许医疗装置通过的空气空间。

公开(公告)号：US07510719B2

公开(公告)日：2009-03-31

申请号：US11295437

申请日：2005-12-07

申请人： Qi Dang ,  Richard Schwartz

发明人： Qi Dang ,  Richard Schwartz

IPC分类号： A61K39/145 ,  A61K39/00 ,  A61K39/295 ,  A61K39/12 ,  C12P21/04 ,  A61K39/20

CPC分类号： C12N7/00 ,  A61K39/12 ,  A61K39/145 ,  C12N2760/16211 ,  C12N2760/16234 ,  C12N2760/16261

摘要： Methods and compositions for the optimization and production of influenza viruses, e.g., ca influenza B strains, in eggs and host cells suitable as influenza vaccines are provided.

摘要翻译： 提供了用于优化和生产适合作为流感疫苗的鸡蛋和宿主细胞中的流感病毒例如流感乙型流感病毒株的方法和组合物。