公开(公告)号：US20080298846A1

公开(公告)日：2008-12-04

申请号：US12130734

申请日：2008-05-30

申请人： Toshihide Ohgoshi ,  Koichi Mihara ,  Hideaki Kurimoto ,  Hiroshi Kubota

发明人： Toshihide Ohgoshi ,  Koichi Mihara ,  Hideaki Kurimoto ,  Hiroshi Kubota

IPC分类号： G03G15/08

CPC分类号： G03G15/0872 ,  G03G2215/0668

摘要： A toner bottle for containing toner has a cylindrical body and a scraper. The bottle body can be rotated on its axis by a driving source. The scraper is supported movably in the bottle body. The bottle body has an opening and ribs. The toner in the toner bottle is supplied through the opening to a developing unit. When the bottle body rotates, the ribs convey the toner toward the opening. The scraper includes a shaft and a scraping part. The shaft extends over the whole length of the bottle body and supports the scraping part. A portion of the scraping part is in contact with the inner cylindrical surface of the bottle body. When the bottle body rotates, the scraper moves perpendicularly to the axis of the body.

摘要翻译： 用于容纳调色剂的调色剂瓶具有圆筒体和刮刀。 瓶体可以通过驱动源在其轴上旋转。 刮刀可在瓶体中可移动地支撑。 瓶身有开口和肋骨。 调色剂瓶中的调色剂通过开口供应到显影单元。 当瓶体旋转时，肋向着开口传送调色剂。 刮刀包括轴和刮削部。 轴在瓶体的整个长度上延伸并支撑刮削部分。 刮擦部分的一部分与瓶体的内圆柱表面接触。 当瓶体旋转时，刮刀垂直于身体的轴线移动。

公开(公告)号：US07456017B2

公开(公告)日：2008-11-25

申请号：US10135700

申请日：2002-05-01

申请人： Hiroshi Kubota ,  Lola M. Reid

发明人： Hiroshi Kubota ,  Lola M. Reid

IPC分类号： C12N5/06 ,  C12N5/08

CPC分类号： C12N5/0672 ,  C12N2500/20 ,  C12N2500/25 ,  C12N2500/36 ,  C12N2500/90 ,  C12N2501/11 ,  C12N2501/39 ,  C12N2502/13

摘要： A method of propagating mammalian endodermally derived progenitors such as hepatic progenitors, their progeny, or mixtures thereof is developed which includes culturing mammalian progenitors, their progeny, or mixtures thereof on a layer of embryonic mammalian feeder cells in a culture medium. The culture medium can be supplemented with one or more hormones and other growth agents. These hormones and other growth agents can include insulin, dexamethasone, transferrin, nicotinamide, serum albumin, β-mercaptoethanol, free fatty acid, glutamine, CuSO4, and H2SeO3. The culture medium can also include antibiotics. Importantly, the culture medium does not include serum.The invention includes means of inducing the differentiation of the progenitors to their adult fates such as the differentiation of hepatic progenitor cells to hepatocytes or biliary cells by adding, or excluding epidermal growth factor, respectively.The method of producing mammalian progenitors is useful in that the progenitors can be used subsequently in one or more of the following processes: identification of growth and differentiation factors, toxicological studies, drug development, antimicrobial studies, or the preparation of an extracorporeal organ such as a bioartificial liver.

摘要翻译： 开发了传播哺乳动物内皮祖细胞如肝祖细胞，其后代或其混合物的方法，其包括在培养基中的胚胎哺乳动物饲养细胞层上培养哺乳动物祖细胞，其后代或其混合物。 培养基可以补充一种或多种激素和其它生长剂。 这些激素和其它生长剂可包括胰岛素，地塞米松，转铁蛋白，烟酰胺，血清白蛋白，β-巯基乙醇，游离脂肪酸，谷氨酰胺，CuSO 4和H 2 SeO 3 。 培养基也可以包括抗生素。 重要的是，培养基不包括血清。 本发明包括诱导祖细胞分化成其成体的方法，例如通过分别添加或排除表皮生长因子将肝祖细胞分化为肝细胞或胆汁细胞。 生产哺乳动物祖细胞的方法是有用的，因为可以随后在以下一个或多个方法中使用祖细胞：识别生长和分化因子，毒理学研究，药物开发，抗微生物研究或体外器官的制备，例如 生物人造肝。

公开(公告)号：US20080101172A1

公开(公告)日：2008-05-01

申请号：US11976815

申请日：2007-10-29

申请人： Hiroshi Kubota

发明人： Hiroshi Kubota

IPC分类号： G11B7/00

CPC分类号： G11B7/094 ,  G11B7/00375

摘要： According to one embodiment, an optical disc apparatus provides a stable tracking error signal for aligning the center of a track or record mark string with the center of a laser beam irradiated to a recording surface by an object lens, when an object lens is moved along the radial direction of an optical disc, by adding an output corrected to be able to reduce the influence of an offset deviation component obtained by a second processing of an adder, to an offset obtained by a first processing of an adder, when a defect or adhesion of material affecting optical characteristics is detected on a recording medium.

摘要翻译： 根据一个实施例，光盘装置提供稳定的跟踪误差信号，用于当轨道或记录标记串的中心与通过物镜照射到记录表面的激光束的中心对准时，当物镜沿着 通过将校正后的输出相加，将通过加法器的第二处理获得的偏移偏差成分的影响加到由加法器的第一处理获得的偏移量上，当缺陷或 在记录介质上检测到影响光学特性的材料的附着。

公开(公告)号：US20080009057A1

公开(公告)日：2008-01-10

申请号：US11753326

申请日：2007-05-24

申请人： Hiroshi Kubota ,  Lola Reid

发明人： Hiroshi Kubota ,  Lola Reid

IPC分类号： C12N5/00

CPC分类号： C12N5/0018 ,  C12N5/067 ,  C12N5/0672 ,  C12N2500/00 ,  C12N2500/05 ,  C12N2500/20 ,  C12N2500/25 ,  C12N2500/32 ,  C12N2500/36 ,  C12N2500/38 ,  C12N2500/90 ,  C12N2501/00 ,  C12N2501/11 ,  C12N2501/235 ,  C12N2501/33 ,  G01N33/56966

摘要： The present invention relates to precursor cells to hepatic stellate cells, compositions comprising same and methods of isolating same. The surface antigenic profile of the precursors is MHC class Ia negative, ICAM-1+, VCAM-1+, β3-integrin+. In addition to expression of these surface markers, the cells also express the intracellular markers desmin, vimentin, smooth muscle α-actin, nestin, hepatocyte growth factor, stromal derived factor-1α and H1x homeobox transcriptional factor.

摘要翻译： 本发明涉及肝星状细胞的前体细胞，包含其的组合物及其分离方法。 前体的表面抗原谱是MHC Ia类阴性，ICAM-1 +，VCAM-1 +，β3-整联蛋白+。 除了这些表面标志物的表达外，细胞还表达细胞内标志物结蛋白，波形蛋白，平滑肌α-肌动蛋白，巢蛋白，肝细胞生长因子，基质衍生因子-1α和H1x同源异体转录因子。

公开(公告)号：US07313426B2

公开(公告)日：2007-12-25

申请号：US11090239

申请日：2005-03-28

申请人： Sunao Takeda ,  Naoki Kobayashi ,  Hiroshi Kubota

发明人： Sunao Takeda ,  Naoki Kobayashi ,  Hiroshi Kubota

IPC分类号： A61B5/00

CPC分类号： A61B5/14551 ,  A61B5/14532 ,  A61B2560/0209

摘要： In an apparatus for determining a concentration of a light absorbing substance in blood, a plurality of photo emitters are adapted to emit light beams having different wavelengths toward a living tissue including a blood vessel. A photo receiver is adapted to receive the light beams which have been transmitted through or reflected from the living tissue. A driver inputs driving currents for causing the respective photo emitters to emit the light beams. An optimizer obtains values of AC components of the light beams received by the photo receiver, and adjusts values of the driving currents such that the values of the AC components fall within a predetermined range.

摘要翻译： 在用于测定血液中的光吸收物质的浓度的装置中，多个光发射器适于向包括血管的生物体组织发射具有不同波长的光束。 光接收器适于接收已经通过活体组织传播或反射的光束。 A驱动器输入用于使各个光发射器发射光束的驱动电流。 优化器获得由光接收器接收的光束的AC分量的值，并且调整驱动电流的值，使得AC分量的值落在预定范围内。

公开(公告)号：US20070119708A1

公开(公告)日：2007-05-31

申请号：US11602983

申请日：2006-11-22

申请人： Seiji Oya ,  Tomohiro Wakazono ,  Koji Shiotani ,  Tomonori Kondo ,  Mineji Nasu ,  Hiroshi Kubota ,  Kazuo Yanada ,  Koichi Awano

发明人： Seiji Oya ,  Tomohiro Wakazono ,  Koji Shiotani ,  Tomonori Kondo ,  Mineji Nasu ,  Hiroshi Kubota ,  Kazuo Yanada ,  Koichi Awano

IPC分类号： G01N27/26 ,  G01F1/64

CPC分类号： G01N33/0037 ,  G01N27/4175 ,  Y02A50/245

摘要： In a sensor diagnosis process, a controller for controlling an NOx gas sensor performs processing of changing the oxygen partial pressure in a second measurement chamber by changing the oxygen partial pressure in a first measurement chamber (S190), processing of detecting a current flowing through a second pump cell before the change of the oxygen partial pressure (S180), and processing of detecting a current flowing through the second pump cell after the change of the oxygen partial pressure (S230). Furthermore, the controller performs processing of judging whether or not the ratio between the current values detected by the respective current detecting unit falls within an allowable range, judging that the second pump cell 113 is in a normal state if the ratio between the current values falls within the allowable range, and judging that the second pump cell 113 is in a deteriorated state if the ratio between the current values is out of the allowable range (S240 and S250).

摘要翻译： 在传感器诊断过程中，用于控制NOx气体传感器的控制器通过改变第一测量室中的氧分压来执行改变第二测量室中的氧分压的处理（S 190），检测流过的电流的处理 在氧分压变化之前的第二泵电池（S1080），以及在氧分压变化之后检测流过第二泵电池的电流的处理（S 230）。 此外，控制器执行判断由各个电流检测单元检测的电流值之间的比率是否落在容许范围内的判断处理，如果当前值之间的比率下降，则判定第二泵浦单元113处于正常状态 在容许范围内，如果电流值之间的比例在允许范围之外，则判定第二泵电池113处于劣化状态（S 240和S 250）。

公开(公告)号：US20060087258A1

公开(公告)日：2006-04-27

申请号：US10550447

申请日：2004-03-11

申请人： Hiroshi Kubota ,  Toshiyuki Hiraoka ,  Shinya Hakuta ,  Tsutomu Araki ,  Shinichiro Matsumoto ,  Mari Nakamura

发明人： Hiroshi Kubota ,  Toshiyuki Hiraoka ,  Shinya Hakuta ,  Tsutomu Araki ,  Shinichiro Matsumoto ,  Mari Nakamura

IPC分类号： H05B37/02 ,  H05B41/36

CPC分类号： H05B41/295 ,  H01J5/54 ,  H01J61/54 ,  Y02B20/19

摘要： An electrolytic capacitor and a ballast choke of a lighting circuit, are disposed on a first face of a circuit board facing a base, and a one-package switch of the lighting circuit is disposed on a second face, facing a fluorescent lamp. The one-package switch comprises field effect transistors contained in a single package and serve as two inverter switches for driving the fluorescent lamp. The one-package switch is a generally rectangular SMD with dimensions of not more than 6 mm respectively in length and width and mounted on the second face of the circuit board by means of terminals of the one-package switch. The one-package switch enhances heat dissipation properties of the circuit, enables the reduction of its dimensions, and increases the mounting efficiency.

摘要翻译： 在面向基座的电路板的第一面上设置电解电容器和照明电路的镇流器，并且照明电路的单包开关设置在面对荧光灯的第二面上。 单包开关包括单个封装中包含的场效应晶体管，并且用作驱动荧光灯的两个反相器开关。 单组件开关是长度和宽度分别尺寸不超过6mm的大致矩形的SMD，通过单组件开关的端子安装在电路板的第二面上。 单组件开关增强了电路的散热性能，可以减小其尺寸，并提高了安装效率。

公开(公告)号：USD516543S1

公开(公告)日：2006-03-07

申请号：US29213836

申请日：2004-09-23

申请人： Hiroshi Kubota

设计人： Hiroshi Kubota

公开(公告)号：US06658128B1

公开(公告)日：2003-12-02

申请号：US09300499

申请日：1999-04-28

申请人： Tsutomu Yoshioka ,  Yasuhiro Fukunaka ,  Hiroshi Kubota ,  Ken Iwayama

发明人： Tsutomu Yoshioka ,  Yasuhiro Fukunaka ,  Hiroshi Kubota ,  Ken Iwayama

IPC分类号： H04R102

CPC分类号： H04R1/30

摘要： An electroacoustic transducer of a horn loudspeaker emits sound, which is supplied through a sound conduit pipe to a horn and propagated out of the horn through a mouth of the horn. The sound conduit pipe is coupled to the horn via a rectangular opening in the upper one of the upper and lower walls forming the horn, to thereby provide a linear sound source for the loudspeaker. The location where the sound conduit pipe is coupled to the horn and/or the tilt angle of the sound conduit pipe with respect to the horn may be varied to control the sound radiation characteristic of the loudspeaker.

摘要翻译： 喇叭扬声器的电声换能器发出声音，其通过声音导管提供给喇叭，并通过喇叭口传播出喇叭。 声导管通过形成喇叭的上壁和下壁中的上侧的矩形开口连接到喇叭，从而为扬声器提供线性声源。 可以改变声管道耦合到喇叭的位置和/或声导管相对于喇叭的倾斜角度，以控制扬声器的声辐射特性。

公开(公告)号：US06562903B2

公开(公告)日：2003-05-13

申请号：US09870776

申请日：2001-06-01

申请人： Teruzo Toui ,  Hisaki Tanabe ,  Nobuhisa Sudo ,  Hiroshi Kubota ,  Takakazu Yamane

发明人： Teruzo Toui ,  Hisaki Tanabe ,  Nobuhisa Sudo ,  Hiroshi Kubota ,  Takakazu Yamane

IPC分类号： C08F800

CPC分类号： C09D133/064 ,  B05D7/576 ,  B05D7/577 ,  C08L33/064 ,  C08L43/04 ,  C09D143/04 ,  C08L2666/04

摘要： A clear coating for top coating of automobiles which comprises a half-esterified acid group-containing acrylic copolymer (I) and a silicate-grafted acrylic copolymer (II) as resin constituents, said half-esterified acid group-containing acrylic copolymer (I) being obtainable by: preparing a copolymer from an acid anhydride group-containing, radical-polymerizable monomer (I-a) and another radical-polymerizable monomer (I-b) and then half-esterifying said acid anhydride group with a low-molecular alcohol compound, said silicate-grafted copolymer (II) being obtainable by grafting a silicate compound (II-B) onto a hydrolyzable silyl-containing copolymer (II-A), the amount of said silicate compound (II-B) grafted being 5 to 50% by mass (on solids basis) relative to the total amount of said resin constituents.

摘要翻译： 含有半酯化酸基的丙烯酸共聚物（I）和作为树脂成分的硅酸酯接枝丙烯酸共聚物（II）的汽车顶涂层用透明涂层，所述含半酯化酸基的丙烯酸共聚物（I）为 可通过以下方法获得：由含酸酐基团的可自由基聚合的单体（Ia）和另一种可自由基聚合的单体（Ib）制备共聚物，然后用低分子量醇化合物半酯化所述酸酐基团， 接枝共聚物（II）可通过将硅酸盐化合物（II-B）接枝到可水解甲硅烷基的共聚物（II-A）上获得，所述接枝的硅酸盐化合物（II-B）的量为5〜50质量％ 基于固体）相对于所述树脂成分的总量。