公开(公告)号：US07960594B2

公开(公告)日：2011-06-14

申请号：US12734601

申请日：2008-10-31

Applicant: Tao Zhang ,  Mingyuan Zheng ,  Na Ji ,  Aigin Wang ,  Yuying Shu ,  Hui Wang ,  Xiaodong Wang ,  Jingguang Chen

Inventor： Tao Zhang ,  Mingyuan Zheng ,  Na Ji ,  Aigin Wang ,  Yuying Shu ,  Hui Wang ,  Xiaodong Wang ,  Jingguang Chen

IPC: C07C29/00

CPC classification number: C07C29/00 ,  B01J21/063 ,  B01J21/18 ,  B01J23/652 ,  B01J23/6527 ,  B01J23/85 ,  B01J23/888 ,  B01J27/19 ,  B01J27/22 ,  B01J27/25 ,  Y02P20/52 ,  C07C31/202

Abstract: A method for preparing ethylene glycol from cellulose uses the cellulose as the feed for the reaction. The cellulose conversion is performed over catalysts which are composed of the metallic state, carbides, nitrides, or phosiphides of molybdenum or tungsten, and metallic cobalt, nickel, ruthenium, rhodium, palladium, iridium, and platinum of the group 8, 9, or 10 transition metals. The catalytic conversion of cellulose is conducted at 120 to 300° C. and hydrogen pressure 1 to 12 MPa under the hydrothermal conditions to achieve the high efficiency, high selectivity, and high yield of ethylene glycol. Compared to the existing method of preparing ethylene glycol from ethylene, the method, using the renewable raw material for the reaction, is friendly to the environment, and has high atom economy.

Abstract translation: 从纤维素制备乙二醇的方法使用纤维素作为反应的进料。 纤维素转化在由金属状态，碳化物，氮化物或钼或钨的高温以及金属钴，镍，钌，铑，钯，铱和铂组成的催化剂上进行，第8,9或9族 10个过渡金属。 在水热条件下，纤维素的催化转化率为120〜300℃，氢压为1〜12MPa，达到乙二醇的高效率，高选择性和高产率。 与从乙烯制备乙二醇的现有方法相比，使用可再生原料进行反应的方法对环境友好，原子经济性好。

公开(公告)号：US20110129485A1

公开(公告)日：2011-06-02

申请号：US12992662

申请日：2009-05-18

Applicant: Hui Wang ,  Anton P.J. Middelberg ,  Lizhong He

Inventor： Hui Wang ,  Anton P.J. Middelberg ,  Lizhong He

IPC: A61K39/00 ,  C07K14/00 ,  C07H21/00 ,  C07H21/04 ,  C12N15/63 ,  C07K16/18 ,  A61K31/7088 ,  A61K38/16 ,  A61P37/02 ,  A61K31/711

CPC classification number: C07K14/4726 ,  A61K38/00 ,  C12N2500/50

Abstract: An isolated modified galectin-2 protein comprising a mutation and/or modification which improves one or more properties of said isolated modified galectin-2 are provided. More particularly, the mutation of galectin-2 is substitution of cysteine 57, preferably with a methionine residue. Modification of an isolated galectin-2 includes a modification of cysteine 75. Modification includes chemical modification by PEGylation or alkylation. Also provided are isolated nucleic acid, genetic constructs comprising said isolated nucleic acids, antibodies, compositions and methods of modulating an immune response that may be useful in therapeutic and/or prophylactic treatment of disease, disorders or considers which involve an immune response is mediated by one or more cytokines or other soluble immunomodulators and/or the immune response is mediated by one or more cells of the immune system.

Abstract translation: 提供了包含改善所述分离的修饰半乳凝素-2的一种或多种性质的突变和/或修饰的分离的修饰的半乳凝素-2蛋白。 更具体地，半乳凝素-2的突变是半胱氨酸57的取代，优选与甲硫氨酸残基取代。 分离的半乳凝素-2的修饰包括半胱氨酸75的修饰。修饰包括通过PEG化或烷基化的化学修饰。 还提供了分离的核酸，包含所述分离的核酸，抗体，组合物和调节可能用于治疗和/或预防性治疗涉及免疫应答的治疗和/或预防性治疗的免疫应答的基因构建体的遗传构建， 一种或多种细胞因子或其他可溶性免疫调节剂和/或免疫应答由免疫系统的一个或多个细胞介导。

公开(公告)号：US20100139710A1

公开(公告)日：2010-06-10

申请号：US12452367

申请日：2007-07-05

Applicant: Hui Wang ,  Jian Wang ,  Yue Ma ,  Chuan He

Inventor： Hui Wang ,  Jian Wang ,  Yue Ma ,  Chuan He

IPC: B08B3/12 ,  B08B13/00 ,  B08B3/08

CPC classification number: H01L21/02041 ,  B08B3/12 ,  H01L21/02052 ,  H01L21/02063 ,  H01L21/6704 ,  H01L21/67051

Abstract: An apparatus for cleaning a surface of wafer or substrate includes a plate being positioned with a gap to surface of the wafer or substrate, and the plate being rotated around an axis vertical to surface of wafer or substrate. The rotating plate surface facing surface of the wafer or substrate has grooves, regular patterns, and irregular patterns to enhance the cleaning efficiency. Another embodiment further includes an ultra sonic or mega sonic transducer vibrating the rotating plate during cleaning process.

Abstract translation: 用于清洁晶片或基板的表面的设备包括板，其定位成与晶片或基板的表面间隔开，并且板围绕垂直于晶片或基板表面的轴线旋转。 晶片或基板的旋转板表面相对表面具有凹槽，规则图案和不规则图案以提高清洁效率。 另一个实施例还包括在清洁过程中振动旋转板的超声波或超声波传感器。

公开(公告)号：US20100087329A1

公开(公告)日：2010-04-08

申请号：US12512852

申请日：2009-07-30

Applicant: Hui Wang

Inventor： Hui Wang

IPC: C40B30/04 ,  C12P19/34

CPC classification number: C12P19/34 ,  C12Q1/6806 ,  C12Q1/6809 ,  C12Q2525/197 ,  C12Q2521/501 ,  C12Q2521/119

Abstract: Methods are described in which a sample containing RNA is contacted with an enzyme having an RNA ligation activity in the presence of a labeled substrate to provide labeled RNA. Methods of performing an array analysis of a labeled RNA sample are also described.

Abstract translation: 描述了在标记的底物存在下将含有RNA的样品与具有RNA连接活性的酶接触以提供标记的RNA的方法。 还描述了对标记的RNA样品进行阵列分析的方法。

公开(公告)号：US20100008460A1

公开(公告)日：2010-01-14

申请号：US12218375

申请日：2008-07-11

Applicant: Liang- Zhang ,  Hui Wang ,  Yong Wang

Inventor： Liang- Zhang ,  Hui Wang ,  Yong Wang

IPC: H04L7/00

CPC classification number: H04L25/14

Abstract: A method and system for performing clock calibration and de-skew on a multi-lane high speed serial interface is presented. Each of a plurality of serial lane transceivers associated with an individual bit lane receives a first data frame, comprising a training sequence header pattern. Based on each of the first data frames, the plurality of serial lane transceivers de-skew a plurality of data frames and generate a plurality of event signals. Using the plurality of event signals, a core clock, having a first phase, is adjusted to be phase aligned with the slowest bit lane.

Abstract translation: 提出了一种用于在多通道高速串行接口上​​执行时钟校准和去偏移的方法和系统。 与单个位通道相关联的多个串行通道收发器中的每一个接收包括训练序列头部模式的第一数据帧。 基于第一数据帧中的每一个，多个串行通道收发器对多个数据帧进行偏移，并产生多个事件信号。 使用多个事件信号，具有第一相位的核心时钟被调整为与最慢位通道相位对准。

公开(公告)号：US07645578B2

公开(公告)日：2010-01-12

申请号：US11591260

申请日：2006-10-31

Applicant: Hui Wang

Inventor： Hui Wang

IPC: C12Q1/68 ,  C07K14/00

CPC classification number: C12Q1/6806 ,  C12Q2525/207 ,  C12Q2521/301

Abstract: The invention relates to methods for treating samples of RNA. In an embodiment the method includes contacting the sample of RNA with a set of oligodeoxynucleotides to provide a DNA/RNA duplex. The method includes contacting the DNA/RNA duplex with an enzyme having a DNA:RNA nuclease activity to provide a digested RNA sample. Kits in accordance with the invention are also described.

Abstract translation: 本发明涉及用于处理RNA样品的方法。 在一个实施方案中，该方法包括将RNA样品与一组寡脱氧核苷酸接触以提供DNA / RNA双链体。 该方法包括使DNA / RNA双链体与具有DNA：RNA核酸酶活性的酶接触以提供消化的RNA样品。 还描述了根据本发明的试剂盒。

公开(公告)号：US20090325813A1

公开(公告)日：2009-12-31

申请号：US12215302

申请日：2008-06-26

Applicant: Hui Wang ,  Bo U. Curry

Inventor： Hui Wang ,  Bo U. Curry

IPC: C40B30/04 ,  C40B40/06

CPC classification number: C12Q1/6837 ,  C12Q2545/113 ,  C12Q2525/207

Abstract: Aspects of the disclosure are generally directed to methods, probes, probe compositions and kits for detecting or quantifying target oligonucleotides. In some embodiments, there are provided methods for determining the level of target oligonucleotides, such as a small RNA (e.g., miRNA), in a sample. In some embodiments, the methods comprise analyzing hybridization of target oligonucleotides to a test microarray; analyzing hybridization of a known amount of reference oligonucleotides (having the same sequences as the target oligonucleotides) to a calibration microarray; and determining the level of the target oligonucleotides in the sample by comparing the hybridization of the target oligonucleotides with the hybridization of the reference oligonucleotides.

Abstract translation: 本公开的方面通常涉及用于检测或定量靶寡核苷酸的方法，探针，探针组合物和试剂盒。 在一些实施方案中，提供了用于确定样品中靶寡核苷酸水平的方法，例如小RNA（例如miRNA）。 在一些实施方案中，所述方法包括分析靶寡核苷酸与测试微阵列的杂交; 分析已知量的参考寡核苷酸（具有与靶寡核苷酸相同的序列）与校准微阵列的杂交; 并通过比较靶寡核苷酸的杂交与参考寡核苷酸的杂交来确定样品中靶寡核苷酸的水平。

公开(公告)号：US07572585B2

公开(公告)日：2009-08-11

申请号：US11496831

申请日：2006-07-31

Applicant: Hui Wang

Inventor： Hui Wang

IPC: C12Q1/68 ,  C12P19/34

CPC classification number: C12P19/34 ,  C12Q1/6806 ,  C12Q1/6809 ,  C12Q2525/197 ,  C12Q2521/501 ,  C12Q2521/119

Abstract: Methods are described in which a sample containing RNA is contacted with an enzyme having an RNA ligation activity in the presence of a labeled substrate to provide labeled RNA. Methods of performing an array analysis of a labeled RNA sample are also described.

Abstract translation: 描述了在标记的底物存在下将含有RNA的样品与具有RNA连接活性的酶接触以提供标记的RNA的方法。 还描述了对标记的RNA样品进行阵列分析的方法。

公开(公告)号：USD592136S1

公开(公告)日：2009-05-12

申请号：US29321879

申请日：2008-07-25

Applicant: Ping-Chuan Chu ,  Hui Wang

Designer： Ping-Chuan Chu ,  Hui Wang

公开(公告)号：US20090108342A1

公开(公告)日：2009-04-30

申请号：US11931606

申请日：2007-10-31

Applicant: Hui Wang ,  Gennadiy Nemtsev ,  Yingping Zheng ,  Gordon M. Grivna

Inventor： Hui Wang ,  Gennadiy Nemtsev ,  Yingping Zheng ,  Gordon M. Grivna

IPC: H01L29/78 ,  H01L21/336

CPC classification number: H01L29/407 ,  H01L29/4236 ,  H01L29/42376 ,  H01L29/456 ,  H01L29/4925 ,  H01L29/4933 ,  H01L29/513 ,  H01L29/66719 ,  H01L29/66727 ,  H01L29/66734 ,  H01L29/7811

Abstract: A semiconductor component that includes a field plate and a semiconductor device and a method of manufacturing the semiconductor component. A semiconductor material includes an epitaxial layer disposed on a semiconductor substrate. A trench having an upper portion and a lower portion is formed in the epitaxial layer. A portion of a field plate is formed in the lower portion of the trench, wherein the field plate is electrically isolated from trench sidewalls. A gate structure is formed in the upper portion of the trench, wherein a gate oxide is formed from opposing sidewalls of the trench. Gate electrodes are formed adjacent to the gate oxide formed from the opposing sidewalls and a dielectric material is formed adjacent to the gate electrode. Another portion of the field plate is formed in the upper portion of the trench and cooperates with the portion of the field plate formed in the lower portion of the trench to form the field plate.

Abstract translation: 包括场板和半导体器件的半导体部件以及半导体部件的制造方法。 半导体材料包括设置在半导体衬底上的外延层。 在外延层中形成具有上部和下部的沟槽。 场板的一部分形成在沟槽的下部，其中场板与沟槽侧壁电隔离。 栅极结构形成在沟槽的上部，其中栅极氧化物由沟槽的相对的侧壁形成。 栅电极与由相对的侧壁形成的栅极氧化物相邻形成，并且与栅电极相邻形成电介质材料。 场板的另一部分形成在沟槽的上部，并且与形成在沟槽的下部中的场板的部分配合以形成场板。