利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

81 条记录 (耗时 0.037 秒)

    Self-cleaning brush with a flexible matrix
    31.
    发明申请
    Self-cleaning brush with a flexible matrix 审中-公开

    公开(公告)号：US20080052844A1

    公开(公告)日：2008-03-06

    申请号：US11977263

    申请日：2007-10-24

    申请人： William McKay

    发明人： William McKay

    IPC分类号： A46B13/02 ,  A01K13/00 ,  A45D24/00 ,  A45D24/42

    CPC分类号： A01K13/002 ,  A46B13/023 ,  A46B15/0002 ,  A46B17/06 ,  A46B2200/104 ,  A46B2200/1093

    摘要： A brush assembly includes a handle and a brush head attached to the handle. The brush head includes a base with a plurality of integral bristles and a matrix. The matrix is made of sponge, foam or other compressible material. As the brush is used on a person or an animal skin or scalp, the hair or fur causes the matrix to compress and expose the bristles. When the brush is removed, the matrix springs back and removes any hair, fur, or other material entangled in the hair. Optionally a vibrating device is incorporated into the brush to provide massaging of the skin and/or scalp.

    Stain and odor detection and cleanup system
    33.
    发明申请
    Stain and odor detection and cleanup system 审中-公开
    污渍和气味检测和清理系统

    公开(公告)号：US20070189834A1

    公开(公告)日：2007-08-16

    申请号：US11387992

    申请日：2006-03-22

    申请人： William McKay

    发明人： William McKay

    IPC分类号： A46B11/00 ,  B43K29/00

    CPC分类号： A47L13/12 ,  A46B11/00 ,  A46B15/0002 ,  A46B15/0036 ,  A46B15/0091 ,  A47L13/26 ,  A47L13/51

    摘要： A method and apparatus for detecting stains, urine, odor and feces, and more particularly, the combination of a black light detector and a liquid reservoir and/or trigger pump dispensing vehicle for containing stain removing chemicals is provided. The black light is selectively and removably mounted or positioned in the body of the dispensing vehicle.

    摘要翻译： 提供了用于检测污渍，尿，气味和粪便的方法和装置，更具体地，提供了用于含有去污化学物质的黑光检测器和液体储存器和/或触发泵分配车辆的组合。 黑色光线被选择性地可拆卸地安装或定位在分配车辆的主体中。

    Methods of inducing or increasing the expression of proteoglycans such as aggrecan in cells
    34.
    发明申请
    Methods of inducing or increasing the expression of proteoglycans such as aggrecan in cells 审中-公开
    在细胞中诱导或增加蛋白聚糖如聚集蛋白聚糖的表达的方法

    公开(公告)号：US20070134218A1

    公开(公告)日：2007-06-14

    申请号：US11602805

    申请日：2006-11-21

    申请人： William McKay ,  Scott Boden ,  Sangwook Yoon

    发明人： William McKay ,  Scott Boden ,  Sangwook Yoon

    IPC分类号： A61K48/00

    CPC分类号： A61K38/1841 ,  A61K38/1875 ,  A61K48/005 ,  A61K48/0075 ,  C07K14/51

    摘要： Methods of inducing the expression of a proteoglycan such as aggrecan in a cell are described. A method is described which includes transfecting a cell with an isolated nucleic acid comprising a nucleotide sequence encoding a LIM mineralization protein operably linked to a promoter. The LIM mineralization protein can be rLMP, hLMP-1, hLMP-1s, or hLMP-3. Transfection maybe accomplished ex vivo or in vivo by direct injection of virus or naked DNA, or by a nonviral vector such as a plasmid. The method can be used to induce proteoglycan synthesis in osseous cells or to stimulate proteoglycan and/or collagen production in cells capable of producing proteoglycan and/or collagen (e.g., intervertebral disc cells including cells of the nucleus pulposus and annulus fibrosus).

    摘要翻译： 描述了在细胞中诱导蛋白聚糖如聚集蛋白聚糖表达的方法。 描述了一种方法，其包括用分离的核酸转染细胞，所述分离的核酸包含可操作地连接于启动子的编码LIM矿化蛋白的核苷酸序列。 LIM矿化蛋白可以是rLMP，hLMP-1，hLMP-1或hLMP-3。 转染可以通过直接注射病毒或裸DNA或通过非病毒载体如质粒在体内或体内完成。 该方法可用于在骨细胞中诱导蛋白聚糖合成或刺激能够产生蛋白聚糖和/或胶原的细胞（例如包括髓核细胞和纤维环的椎间盘细胞）中的蛋白聚糖和/或胶原产生。

    Multi-purpose medical implant devices
    36.
    发明申请
    Multi-purpose medical implant devices 有权

    公开(公告)号：US20060247791A1

    公开(公告)日：2006-11-02

    申请号：US11118081

    申请日：2005-04-29

    申请人： William McKay ,  Jeffrey Scifert

    发明人： William McKay ,  Jeffrey Scifert

    IPC分类号： A61F2/28 ,  A61F2/02

    CPC分类号： A61L27/50 ,  A61L27/46 ,  C08L89/06

    摘要： Described are medical devices for supporting or inducing bone growth including an implant body defining one or more separation-assist lines that facilitate separation of the body into two or more substantially pre-defined pieces. The implant body can be used and implanted as a whole or may be separated into multiple pieces, some or all of which can be used at one or multiple implant sites in a patient. Separation-assist lines in implant bodies can serve a dual role in imparting increased and controlled flexibility to the overall body when used as a whole at an implant site. Also described are methods of making and using, and kits including, such medical devices.

    Lint removal apparatus with pull tab for adhesive coated sheets
    37.
    发明申请
    Lint removal apparatus with pull tab for adhesive coated sheets 审中-公开

    公开(公告)号：US20060174435A1

    公开(公告)日：2006-08-10

    申请号：US11366645

    申请日：2006-03-02

    申请人： William McKay

    发明人： William McKay

    IPC分类号： A47L25/00

    CPC分类号： A47L25/005 ,  Y10T428/24777 ,  Y10T428/28

    摘要： A pull tab is formed at a separable edge of each of a plurality of individually separable sheets of outwardly faced adhesive tape wound into a roll by a non-adhesive portion carried on the adhesive layer of the tape to facilitate gripping and removal of an outermost sheet from the tape roll to expose an underlying sheet. The separable edges extend at least partially through the tape roll dividing the tape into a plurality of separable sheets and across substantially all of the lateral extent of the roll. The separable edge can be two spaced separable edges disposed in registry with each non-adhesive portion to define opposite leading edges.

    Process to treat avascular necrosis (AVN) with osteoinductive materials
    38.
    发明申请
    Process to treat avascular necrosis (AVN) with osteoinductive materials 审中-公开
    用骨诱导材料治疗无血管性坏死（AVN）的方法

    公开(公告)号：US20060057184A1

    公开(公告)日：2006-03-16

    申请号：US10942042

    申请日：2004-09-16

    申请人： Jeffrey Nycz ,  William McKay ,  Jon Serbousek

    发明人： Jeffrey Nycz ,  William McKay ,  Jon Serbousek

    IPC分类号： A61K38/18 ,  A61F2/00

    CPC分类号： A61K38/1875 ,  A61B17/58 ,  A61F2/2814

    摘要： A method of treating avascular necrosis (“AVN”) comprising administering one or more osteoinductive formulations to the site of AVN disease progression. The method involves the combination of a core decompression technique, followed by the introduction of one or more osteoinductive formulations into the decompression core, and concluding with capping of the lateral aspect of the decompression core with a femoral core cap. The osteoinductive formulations of the invention comprise one or more osteoinductive agents and suitable carrier molecules. The femoral core cap retains the osteoinductive formulation within the decompression core, thereby preventing leakage of the osteoinductive formulation from the decompression core. The method of the invention optionally comprises introduction of autograft or allograft with the osteoinductive formulations of the invention. The method of the invention further optionally comprises incorporation of sustained release compositions to provide extended periods of osteogenesis.

    摘要翻译： 一种治疗无血管性坏死（“AVN”）的方法，包括向AVN疾病进展的部位施用一种或多种骨诱导性制剂。 该方法涉及核心减压技术的组合，接着将一种或多种骨诱导性制剂引入减压核心，并且用股骨芯帽盖住减压芯的侧面方面。 本发明的骨诱导制剂包含一种或多种成骨诱导剂和合适的载体分子。 股骨芯帽将骨诱导制剂保留在减压芯内，从而防止骨诱导制剂从减压芯渗漏。 本发明的方法任选地包括用本发明的骨诱导制剂引入自体移植物或同种异体移植物。 本发明的方法还任选地包括并入缓释组合物以提供延长的成骨期。

    Syringe with split/adjustable thumb ring
    40.
    发明申请
    Syringe with split/adjustable thumb ring 审中-公开
    注射器带分流/可调拇指环

    公开(公告)号：US20050209571A1

    公开(公告)日：2005-09-22

    申请号：US11080762

    申请日：2005-03-15

    申请人： William McKay

    发明人： William McKay

    IPC分类号： A61M5/24 ,  A61M5/31 ,  A61M5/315

    CPC分类号： A61M5/3148 ,  A61M5/24 ,  A61M2005/3139

    摘要： A small dental syringe has a spring biased plunger and a split, adjustable thumb receiving member. The dimensions of the syringe result in a shorter, over-all, distance a user must spread his/her thumb from the fingers gripping the syringe for aspirating.

    摘要翻译： 小型牙科注射器具有弹簧偏压柱塞和分开的可调节的拇指接收构件。 注射器的尺寸导致更短的全部距离，使用者必须将其拇指从夹紧注射器的手指伸出。