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公开(公告)号：US11896978B2
公开(公告)日：2024-02-13
申请号：US17032524
申请日：2020-09-25
Applicant: Meso Scale Technologies, LLC.
Inventor： Eli N. Glezer , Stephen Higgins , Sandor Kovacs , Sudeep Kumar , Kenneth Page , Kristian Roth , George Sigal
CPC classification number: B01L7/525 , B01L3/5027 , B01L2200/027 , B01L2200/0605 , B01L2200/0621 , B01L2200/0631 , B01L2200/10 , B01L2200/146 , B01L2200/16 , B01L2300/0645 , B01L2300/087 , B01L2300/0816 , B01L2300/0864 , B01L2300/0867 , B01L2300/0883 , B01L2400/0487 , B01L2400/0688 , B01L2400/0694 , C12Q1/686
Abstract: Assay cartridges are described that have purification, reaction, and detection zones and other fluidic components which can include sample chambers, waste chambers, conduits, vents, reagent chambers, reconstitution chambers and the like. The assay cartridges are used to conduct multiplexed nucleic acid measurements. Also described are kits including such cartridges, methods of using the same, and a reader configured to analyze an assay conducted using an assay cartridge.
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公开(公告)号：US20240027456A1
公开(公告)日：2024-01-25
申请号：US18376575
申请日：2023-10-04
Applicant: Meso Scale Technologies, LLC.
Inventor： Anahit Aghvanyan , Eli N. Glezer , John Kenten , Sudeep Kumar , Galina Nikolenko , Martin Stengelin , Srikant Vaithilingam
IPC: G01N33/574
CPC classification number: G01N33/57423 , G01N2800/52
Abstract: The present invention relates to methods of diagnosing lung cancer in a patient, as well as methods of monitoring the progression of lung cancer and/or methods of monitoring a treatment protocol of a therapeutic agent or a therapeutic regimen. The invention also relates to assay methods used in connection with the diagnostic methods described herein.
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公开(公告)号：US11802877B2
公开(公告)日：2023-10-31
申请号：US16883468
申请日：2020-05-26
Applicant: Meso Scale Technologies, LLC.
Inventor： Anahit Aghvanyan , Eli N. Glezer , John Kenten , Sudeep Kumar , Galina Nikolenko , Martin Stengelin , Srikant Vaithilingam
IPC: G01N33/574
CPC classification number: G01N33/57423 , G01N2800/52
Abstract: The present invention relates to methods of diagnosing lung cancer in a patient, as well as methods of monitoring the progression of lung cancer and/or methods of monitoring a treatment protocol of a therapeutic agent or a therapeutic regimen. The invention also relates to assay methods used in connection with the diagnostic methods described herein.
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公开(公告)号：US11231417B2
公开(公告)日：2022-01-25
申请号：US16815598
申请日：2020-03-11
Applicant: Meso Scale Technologies, LLC.
Inventor： Sudeep Kumar , George Sigal , Michael Tsionsky
IPC: G01N33/543 , G01N33/53 , C12Q1/6823 , C12Q1/6832 , C12Q1/6834
Abstract: The invention relates to methods for conducting binding assays in an assay device that includes one or more storage and use zone. The storage zones of the assay device are configured to house one or more reagents used in an assay conducted in the use zone of the device.
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公开(公告)号：US11135594B2
公开(公告)日：2021-10-05
申请号：US16292521
申请日：2019-03-05
Applicant: Meso Scale Technologies, LLC.
Inventor： Eli N. Glezer , Bandele Jeffrey-Coker , Kenneth Page , Sandor Kovacs , Sudeep Kumar , Kristian Roth
IPC: B01L3/00 , F16K11/074
Abstract: Assay cartridges are described that have a plurality of chambers and a fluidic network that includes fluidic conduits and a multi-port valve designed to selectively connect the valve inlet and one valve outlet through a fluidic connector in the valve as the remaining valve outlets are sealed.
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Patent Agency Ranking
公开(公告)号：US20210116452A1
公开(公告)日：2021-04-22
申请号：US16883468
申请日：2020-05-26
Applicant: Meso Scale Technologies, LLC.
Inventor： Anahit Aghvanyan , Eli N. Glezer , John Kenten , Sudeep Kumar , Galina Nikolenko , Martin Stengelin , Srikant Vaithilingam
IPC: G01N33/574
Abstract: The present invention relates to methods of diagnosing lung cancer in a patient, as well as methods of monitoring the progression of lung cancer and/or methods of monitoring a treatment protocol of a therapeutic agent or a therapeutic regimen. The invention also relates to assay methods used in connection with the diagnostic methods described herein.
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公开(公告)号：US10189023B2
公开(公告)日：2019-01-29
申请号：US14203638
申请日：2014-03-11
Applicant: Meso Scale Technologies, LLC.
Inventor： Eli N. Glezer , Sudeep Kumar , Pankaj Oberoi , George Sigal , Michael Tsionsky
IPC: C07H21/04 , B01L3/00 , C12Q1/6876 , G01N33/543 , C12Q1/6804 , G01N33/68 , C12Q1/6816
Abstract: The invention relates to methods for conducting solid-phase binding assays. One example is an assay method having improved analyte specificity where specificity is limited by the presence of non-specific binding interactions.
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公开(公告)号：US20180156824A1
公开(公告)日：2018-06-07
申请号：US15847111
申请日：2017-12-19
Applicant: Meso Scale Technologies, LLC.
Inventor： Eli N. Glezer , John Kenten , Sudeep Kumar , Galina Nikolenko
IPC: G01N33/68
CPC classification number: G01N33/6893 , G01N2333/4706 , G01N2333/4727 , G01N2333/70578 , G01N2333/70596 , G01N2333/8146 , G01N2800/347 , G01N2800/52
Abstract: The present invention relates to methods of diagnosing a kidney disorder in a patient, as well as methods of monitoring the progression of a kidney disorder and/or methods of monitoring a treatment protocol of a therapeutic agent or a therapeutic regimen. The invention also relates to assay methods used in connection with the diagnostic methods described herein.
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公开(公告)号：US09797894B2
公开(公告)日：2017-10-24
申请号：US13956841
申请日：2013-08-01
Applicant: Meso Scale Technologies, LLC
Inventor： Sudeep Kumar , George Sigal , Michael Tsionsky
IPC: G01N33/53 , C12Q1/68 , C12M1/34 , C40B30/04 , G01N27/00 , G01N21/66 , G01N33/566 , G01N33/543
CPC classification number: G01N33/54386 , C12Q1/6823 , C12Q1/6832 , C12Q1/6834 , G01N33/5306 , G01N2446/00 , G01N2458/30
Abstract: The invention relates to methods for conducting binding assays in an assay device that includes one or more storage and use zone. The storage zones of the assay device are configured to house one or more reagents used in an assay conducted in the use zone of the device.
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公开(公告)号：US20150038365A1
公开(公告)日：2015-02-05
申请号：US14447691
申请日：2014-07-31
Applicant: Meso Scale Technologies, LLC
Inventor： Anahit Aghvanyan , Eli N. Glezer , John Kenten , Sudeep Kumar , Galina Nikolenko , Martin Stengelin , Srikant Vaithilingam
IPC: G01N33/574 , G01N33/50
CPC classification number: G01N33/57423 , G01N2800/52
Abstract: The present invention relates to methods of diagnosing lung cancer in a patient, as well as methods of monitoring the progression of lung cancer and/or methods of monitoring a treatment protocol of a therapeutic agent or a therapeutic regimen. The invention also relates to assay methods used in connection with the diagnostic methods described herein.
Abstract translation: 本发明涉及诊断患者肺癌的方法，以及监测肺癌进展的方法和/或监测治疗剂或治疗方案的治疗方案的方法。 本发明还涉及结合本文所述的诊断方法使用的测定方法。
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