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公开(公告)号：US20060151702A1
公开(公告)日：2006-07-13
申请号：US11366129
申请日：2006-03-02
申请人： Patrick Treado , Matthew Nelson , Scott Keitzer
发明人： Patrick Treado , Matthew Nelson , Scott Keitzer
IPC分类号： G01N21/35
CPC分类号： G01N21/359 , G01J3/2823 , G02B21/0016 , G02B21/06
摘要： A chemical imaging system is provided which uses a near infrared radiation microscope. The system includes an illumination source which illuminates an area of a sample using light in the near infrared radiation wavelength and light in the visible wavelength. A multitude of spatially resolved spectra of transmitted, reflected, emitted or scattered near infrared wavelength radiation light from the illuminated area of the sample is collected and a collimated beam is produced therefrom. A near infrared imaging spectrometer is provided for selecting a near infrared radiation image of the collimated beam. The filtered images are collected by a detector for further processing. The visible wavelength light from the illuminated area of the sample is simultaneously detected providing for the simultaneous visible and near infrared chemical imaging analysis of the sample. Two efficient means for performing three dimensional near infrared chemical imaging microscopy are provided.
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公开(公告)号：US20060050278A1
公开(公告)日：2006-03-09
申请号：US11229539
申请日：2005-09-20
申请人： Patrick Treado , Charles Gardner , Matthew Nelson
发明人： Patrick Treado , Charles Gardner , Matthew Nelson
IPC分类号： G01N21/25
CPC分类号： G01N21/255
摘要： The disclosure relates to method and apparatus for obtaining a multimodal hyperspectral image of a sample for widefield spectral analysis. An apparatus according to one embodiment may include a plurality of optical lenses configured to interchangeably receive photons and focus the photons; a plurality of tunable filters positioned in a filter housing, each tunable filter selectively receiving the focused dispersed photons from one of the plurality of optical lenses, each tunable filter providing wavelength-selective filtered photons; a first optical camera and a second optical cameras for selectively receiving the wavelength-selective filtered photons from each of the plurality of tunable filters and combining said filtered photons to form a hyperspectral spatially accurate, wavelength-resolved image of the sample.
摘要翻译： 本公开涉及用于获得用于宽带光谱分析的样品的多峰高光谱图像的方法和装置。 根据一个实施例的装置可以包括多个配置成互换地接收光子并聚焦光子的光学透镜; 多个可调滤光器，其位于过滤器壳体中，每个可调谐滤光器选择性地从多个光学透镜中的一个透镜接收聚焦的分散的光子，每个可调谐滤光器提供波长选择性滤光的光子; 第一光学摄像机和第二光学摄像机，用于从多个可调谐滤光器中的每一个选择性地接收波长选择性滤波的光子，并组合所述滤波的光子以形成样品的高光谱空间准确的波长分辨图像。
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公开(公告)号：US20060049354A1
公开(公告)日：2006-03-09
申请号：US11257139
申请日：2005-10-24
申请人： Patrick Treado , Matthew Nelson , Scott Keitzer
发明人： Patrick Treado , Matthew Nelson , Scott Keitzer
IPC分类号： G01J5/02
CPC分类号： G01N21/359 , G01J3/2823 , G02B21/0016 , G02B21/06
摘要： A chemical imaging system is provided which uses a near infrared radiation microscope. The system includes an illumination source which illuminates an area of a sample using light in the near infrared radiation wavelength and light in the visible wavelength. A multitude of spatially resolved spectra of transmitted, reflected, emitted or scattered near infrared wavelength radiation light from the illuminated area of the sample is collected and a collimated beam is produced therefrom. A near infrared imaging spectrometer is provided for selecting a near infrared radiation image of the collimated beam. The filtered images are collected by a detector for further processing. The visible wavelength light from the illuminated area of the sample is simultaneously detected providing for the simultaneous visible and near infrared chemical imaging analysis of the sample. Two efficient means for performing three dimensional near infrared chemical imaging microscopy are provided.
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公开(公告)号：US20060036181A1
公开(公告)日：2006-02-16
申请号：US11204196
申请日：2005-08-09
申请人： Patrick Treado , Matthew Nelson
发明人： Patrick Treado , Matthew Nelson
CPC分类号： A61B5/0091 , A61B5/4312 , G01N21/65
摘要： Apparatus and methods for spatially resolved Raman chemical imaging of breast tissue is disclosed. A region of breast tissue is illuminated with monochromatic light. A spatially organized area of endogenous molecules in the tissue is then detected in the region by detecting a Raman shifted light signal. The Raman shifted light signal is spatially resolved in at least one direction and is thus useful for examining breast tissue, especially to detect malignant tissue.
摘要翻译： 公开了用于乳腺组织的空间分辨拉曼化学成像的装置和方法。 乳腺组织区域用单色光照射。 然后通过检测拉曼移动的光信号在该区域中检测组织中的内分子的空间有组织的区域。 拉曼移动的光信号在至少一个方向上被空间分辨，因此可用于检查乳腺组织，特别是用于检测恶性组织。
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公开(公告)号：US08994934B1
公开(公告)日：2015-03-31
申请号：US13373333
申请日：2011-11-10
CPC分类号： G01N33/0057 , G01J3/02 , G01J3/027 , G01J3/44 , G01J5/0846 , G01J5/0859 , G01J2005/0077 , H04N5/23219
摘要： The present disclosure provides for a system and method for detecting and identifying unknown targets. At least one region of interest comprising an unknown target in a sample scene may be targeted using SWIR spectroscopic techniques. A region of interest may be surveyed to thereby determine whether or not a human is present. This surveying may be achieved my assessing LWIR data, data acquired from motion sensors, and combinations thereof. If no human is present in a region of interest, the region may be interrogated using Raman spectroscopic techniques to thereby obtain a Raman data set representative of the region of interest. This Raman data set may be assessed to thereby identify said unknown target. This assessment may be achieved by comparing the Raman data set to a reference data sets in a reference database, where each reference data set is associated with a known target.
摘要翻译： 本公开提供了用于检测和识别未知目标的系统和方法。 可以使用SWIR光谱技术来对包含样本场景中的未知目标的至少一个感兴趣区域进行定位。 可以调查感兴趣的区域，从而确定人是否存在。 本次测量可能会实现我对LWIR数据的评估，运动传感器获取的数据及其组合。 如果感兴趣区域中没有人存在，则可以使用拉曼光谱技术询问该区域，从而获得表示感兴趣区域的拉曼数据集。 可以评估该拉曼数据集，从而识别所述未知目标。 可以通过将拉曼数据集与参考数据库中的参考数据集进行比较来实现该评估，其中每个参考数据集与已知目标相关联。
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36.发明授权公开(公告)号：US08553210B2
公开(公告)日：2013-10-08
申请号：US13209688
申请日：2011-08-15
IPC分类号： G01N21/00
CPC分类号： G01J3/02 , G01J3/0208 , G01J3/0218 , G01J3/0272 , G01J3/28 , G01J3/44 , G01J3/443 , G01N21/35 , G01N21/6402 , G01N21/6456 , G01N21/65 , G01N21/658 , G01N21/718 , G01N2021/6423 , G01N2201/0221 , G01N2201/06113 , G01N2201/08 , G01N2201/101 , G01N2201/1087
摘要： A system and method for locating and identifying unknown samples. A targeting mode may be utilized to scan regions of interest for potential unknown materials. This targeting mode may interrogate regions of interest using SWIR and/or fluorescence spectroscopic and imaging techniques. Unknown samples detected in regions of interest may be further interrogated using a combination of Raman and LIBS techniques to identify the unknown samples. Structured illumination may be used to interrogate an unknown sample. Data sets generated during interrogation may be compared to a reference database comprising a plurality of reference data sets, each associated with a known material. The system and method may be used to identify a variety of materials including: biological, chemical, explosive, hazardous, concealment, and non-hazardous materials.
摘要翻译： 用于定位和识别未知样品的系统和方法。 可以利用定位模式来扫描潜在未知材料的感兴趣区域。 这种瞄准模式可以使用SWIR和/或荧光光谱和成像技术来询问感兴趣的区域。 可以使用拉曼和LIBS技术的组合进一步询问在感兴趣区域中检测到的未知样品，以识别未知样品。 结构化照明可用于询问未知样品。 在询问期间生成的数据集可以与包括多个参考数据集的参考数据库进行比较，每个参考数据集与已知的资料相关联。 该系统和方法可用于识别各种材料，包括：生物，化学，爆炸，危险，隐蔽和非危险材料。
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37.发明授权公开(公告)号：US08547540B2
公开(公告)日：2013-10-01
申请号：US13209670
申请日：2011-08-15
IPC分类号： G01N21/00
CPC分类号： G01J3/02 , G01J3/0218 , G01J3/0272 , G01J3/28 , G01J3/44 , G01J3/443 , G01N21/6456 , G01N21/65 , G01N21/718 , G01N2201/0221 , G01N2201/08
摘要： A system and method for locating and identifying unknown samples. A targeting mode may be utilized to scan regions of interest for potential unknown materials. This targeting mode may interrogate regions of interest using SWIR and/or fluorescence spectroscopic and imaging techniques. Unknown samples detected in regions of interest may be further interrogated using a combination of Raman and LIBS techniques to identify the unknown samples. Structured illumination may be used to interrogate an unknown sample. Data sets generated during interrogation may be compared to a reference database comprising a plurality of reference data sets, each associated with a known material. The system and method may be used to identify a variety of materials including: biological, chemical, explosive, hazardous, concealment, and non-hazardous materials.
摘要翻译： 用于定位和识别未知样品的系统和方法。 可以利用定位模式来扫描潜在未知材料的感兴趣区域。 这种瞄准模式可以使用SWIR和/或荧光光谱和成像技术来询问感兴趣的区域。 可以使用拉曼和LIBS技术的组合进一步询问在感兴趣区域中检测到的未知样品，以识别未知样品。 结构化照明可用于询问未知样品。 在询问期间生成的数据集可以与包括多个参考数据集的参考数据库进行比较，每个参考数据集与已知的资料相关联。 该系统和方法可用于识别各种材料，包括：生物，化学，爆炸，危险，隐蔽和非危险材料。
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38.发明申请公开(公告)号：US20120062874A1
公开(公告)日：2012-03-15
申请号：US13209670
申请日：2011-08-15
IPC分类号： G01N21/00
CPC分类号： G01J3/02 , G01J3/0218 , G01J3/0272 , G01J3/28 , G01J3/44 , G01J3/443 , G01N21/6456 , G01N21/65 , G01N21/718 , G01N2201/0221 , G01N2201/08
摘要： A system and method for locating and identifying unknown samples. A targeting mode may be utilized to scan regions of interest for potential unknown materials. This targeting mode may interrogate regions of interest using SWIR and/or fluorescence spectroscopic and imaging techniques. Unknown samples detected in regions of interest may be further interrogated using a combination of Raman and LIBS techniques to identify the unknown samples. Structured illumination may be used to interrogate an unknown sample. Data sets generated during interrogation may be compared to a reference database comprising a plurality of reference data sets, each associated with a known material. The system and method may be used to identify a variety of materials including: biological, chemical, explosive, hazardous, concealment, and non-hazardous materials.
摘要翻译： 用于定位和识别未知样品的系统和方法。 可以利用定位模式来扫描潜在未知材料的感兴趣区域。 这种瞄准模式可以使用SWIR和/或荧光光谱和成像技术来询问感兴趣的区域。 可以使用拉曼和LIBS技术的组合进一步询问在感兴趣区域中检测到的未知样品，以识别未知样品。 结构化照明可用于询问未知样品。 在询问期间生成的数据集可以与包括多个参考数据集的参考数据库进行比较，每个参考数据集与已知的资料相关联。 该系统和方法可用于识别各种材料，包括：生物，化学，爆炸，危险，隐蔽和非危险材料。
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公开(公告)号：US20110080577A1
公开(公告)日：2011-04-07
申请号：US12899119
申请日：2010-10-06
IPC分类号： G01N21/00
CPC分类号： G01J3/02 , G01J3/0221 , G01J3/0264 , G01J3/2823 , G01J3/36 , G01J3/44 , G01N21/359 , G01N21/65 , G01N21/718 , G01N33/227 , G01N2021/1738 , G01N2021/174 , G01N2021/1744
摘要： A system and method for the detection and identification of explosives and explosive residues using a combination of SWIR, Raman, and LIBS spectroscopy techniques, including imaging. A region of interest may be surveyed to identify a target area, wherein the target area comprises at least one unknown material. This surveying may be accomplished using visible imagery or SWIR imagery. The target area may be interrogated using Raman spectroscopy and LIBS spectroscopy to identify the unknown material. SWIR techniques may also be used to interrogate the target area. Fusion algorithms may also be applied to visible images, SWIR data sets, Raman data sets, and/or LIBS data sets.
摘要翻译： 一种使用SWIR，拉曼和LIBS光谱技术组合检测和识别爆炸物和爆炸物残留物的系统和方法，包括成像。 可以调查感兴趣的区域以识别目标区域，其中目标区域包括至少一种未知材料。 可以使用可见图像或SWIR图像来完成此测量。 可以使用拉曼光谱和LIBS光谱来询问目标区域以识别未知材料。 也可以使用SWIR技术来询问目标区域。 融合算法也可以应用于可见图像，SWIR数据集，拉曼数据集和/或LIBS数据集。
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公开(公告)号：US20060164640A1
公开(公告)日：2006-07-27
申请号：US11366762
申请日：2006-03-02
申请人： Patrick Treado , Matthew Nelson , Scott Keitzer
发明人： Patrick Treado , Matthew Nelson , Scott Keitzer
IPC分类号： G01J3/28
CPC分类号： G01N21/359 , G01J3/2823 , G02B21/0016 , G02B21/06
摘要： A chemical imaging system is provided which uses a near infrared radiation microscope. The system includes an illumination source which illuminates an area of a sample using light in the near infrared radiation wavelength and light in the visible wavelength. A multitude of spatially resolved spectra of transmitted, reflected, emitted or scattered near infrared wavelength radiation light from the illuminated area of the sample is collected and a collimated beam is produced therefrom. A near infrared imaging spectrometer is provided for selecting a near infrared radiation image of the collimated beam. The filtered images are collected by a detector for further processing. The visible wavelength light from the illuminated area of the sample is simultaneously detected providing for the simultaneous visible and near infrared chemical imaging analysis of the sample. Two efficient means for performing three dimensional near infrared chemical imaging microscopy are provided.
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