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公开(公告)号：US06171790B2
公开(公告)日：2001-01-09
申请号：US09071709
申请日：1998-05-01
申请人： Jennifer L. Hillman , Y. Tom Tang , Preeti Lal , Neil C. Corley , Karl J. Guegler , Chandra Patterson
发明人： Jennifer L. Hillman , Y. Tom Tang , Preeti Lal , Neil C. Corley , Karl J. Guegler , Chandra Patterson
IPC分类号： C12N1557
CPC分类号： C07K14/8114 , A61K38/00 , C12N9/48 , C12N9/6421
摘要： The invention provides human protease associated proteins (HPRAP) and polynucleotides which identify and encode HPRAP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating or preventing disorders associated with expression of HPRAP.
摘要翻译： 本发明提供了人类蛋白酶相关蛋白（HPRAP）和识别和编码HPRAP的多核苷酸。 本发明还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂。 本发明还提供用于诊断，治疗或预防与HPRAP表达相关的障碍的方法。
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公开(公告)号：US5817482A
公开(公告)日：1998-10-06
申请号：US879561
申请日：1997-06-20
CPC分类号： C12N9/1205 , A61K38/00
摘要： The invention provides human nucleotide kinases and polynucleotides which identify and encode DRNK. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention also provides methods for treating disorders associated with expression of DRNK.
摘要翻译： 本发明提供鉴定和编码DRNK的人核苷酸激酶和多核苷酸。 本发明还提供表达载体，宿主细胞，激动剂，抗体和拮抗剂。 本发明还提供了治疗与DRNK表达相关的疾病的方法。
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公开(公告)号：US6132964A
公开(公告)日：2000-10-17
申请号：US13881
申请日：1998-02-06
申请人： Olga Bandman , Preeti Lal , Jennifer L. Hillman , Neil C. Corley , Karl J. Guegler , Purvi Shah
发明人： Olga Bandman , Preeti Lal , Jennifer L. Hillman , Neil C. Corley , Karl J. Guegler , Purvi Shah
CPC分类号： C12N9/14 , C12Q1/6883 , C12Q2600/158
摘要： The invention provides human hydrolase-like molecules (HHLM) and polynucleotides which identify and encode HHLM. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for treating or preventing disorders associated with expression of HHLM.
摘要翻译： 本发明提供了人类水解酶样分子（HHLM）和识别和编码HHLM的多核苷酸。 本发明还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂。 本发明还提供治疗或预防与HHLM表达相关的病症的方法。
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公开(公告)号：US6117989A
公开(公告)日：2000-09-12
申请号：US48889
申请日：1998-03-26
申请人： Olga Bandman , Jennifer L. Hillman , Neil C. Corley , Karl J. Guegler , Preeti Lal , Chandra Patterson
发明人： Olga Bandman , Jennifer L. Hillman , Neil C. Corley , Karl J. Guegler , Preeti Lal , Chandra Patterson
IPC分类号： G01N33/68 , A61K38/00 , A61P15/08 , A61P25/00 , A61P35/00 , A61P37/02 , C07K14/47 , C07K16/18 , C12N1/21 , C12N15/09 , C12N15/12 , C12Q1/68 , C07H21/04 , C12N15/11 , C12N15/63
CPC分类号： C07K14/4728 , A61K38/00
摘要： The invention provides human calcium-binding proteins (CaBPs) and polynucleotides which identify and encode CaBP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for treating or preventing disorders associated with expression of CaBP.
摘要翻译： 本发明提供了人钙结合蛋白（CaBPs）和识别和编码CaBP的多核苷酸。 本发明还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂。 本发明还提供了治疗或预防与CaBP表达相关的障碍的方法。
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公开(公告)号：US5962232A
公开(公告)日：1999-10-05
申请号：US16000
申请日：1998-01-30
申请人： Olga Bandman , Jennifer L. Hillman , Preeti Lal , Ingrid E. Akerblom , Purvi Shah , Neil C. Corley , Karl J. Guegler
发明人： Olga Bandman , Jennifer L. Hillman , Preeti Lal , Ingrid E. Akerblom , Purvi Shah , Neil C. Corley , Karl J. Guegler
IPC分类号： G01N33/68 , A61K38/00 , A61K38/45 , A61K45/00 , C07K16/40 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N9/12 , C12N15/09 , C12N15/54 , C12Q1/68 , C12G1/68 , C07H21/02 , C12N1/20 , C12N15/00
CPC分类号： C12N9/1205 , A61K38/00
摘要： The invention provides human protein kinase molecules (HPKM) and polynucleotides which identify and encode HPKM. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for treating or preventing disorders associated with expression of HPKM.
摘要翻译： 本发明提供鉴定和编码HPKM的人蛋白激酶分子（HPKM）和多核苷酸。 本发明还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂。 本发明还提供了治疗或预防与HPKM表达相关的病症的方法。
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公开(公告)号：US5885803A
公开(公告)日：1999-03-23
申请号：US878989
申请日：1997-06-19
申请人： Olga Bandman , Jennifer L. Hillman , Neil C. Corley , Karl J. Guegler , Preeti Lal , Surya K. Goli , Purvi Shah
发明人： Olga Bandman , Jennifer L. Hillman , Neil C. Corley , Karl J. Guegler , Preeti Lal , Surya K. Goli , Purvi Shah
CPC分类号： C12N9/1205 , A61K38/00
摘要： The invention provides human disease associated protein kinases and polynucleotides (collectively designated DAPK) which identify and encode them. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention further provides methods for diagnosing and treating disorders associated with expression of human disease associated protein kinases.
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公开(公告)号：US06518029B1
公开(公告)日：2003-02-11
申请号：US09612473
申请日：2000-07-07
申请人： Olga Bandman , Preeti Lal , Jennifer L. Hillman , Neil C. Corley , Karl J. Guegler , Purvi Shah
发明人： Olga Bandman , Preeti Lal , Jennifer L. Hillman , Neil C. Corley , Karl J. Guegler , Purvi Shah
IPC分类号： C12N914
CPC分类号： C12N9/14 , C12Q1/6883 , C12Q2600/158
摘要： The invention provides human hydrolase-like molecules (HHLM) and polynucleotides which identify and encode HHLM. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for treating or preventing disorders associated with expression of HHLM.
摘要翻译： 本发明提供了人类水解酶样分子（HHLM）和识别和编码HHLM的多核苷酸。 本发明还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂。 本发明还提供治疗或预防与HHLM表达相关的病症的方法。
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公开(公告)号：US06207148B1
公开(公告)日：2001-03-27
申请号：US09272796
申请日：1999-03-19
申请人： Olga Bandman , Jennifer L. Hillman , Neil C. Corley , Karl J. Guegler , Preeti Lal , Surya K. Goli , Purvi Shah
发明人： Olga Bandman , Jennifer L. Hillman , Neil C. Corley , Karl J. Guegler , Preeti Lal , Surya K. Goli , Purvi Shah
IPC分类号： A61K3843
CPC分类号： C12N9/1205 , A61K38/00
摘要： The invention provides human disease associated protein kinases and polynucleotides (collectively designated DAPK) which identify and encode them. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention further provides methods for diagnosing and treating disorders associated with expression of human disease associated protein kinases.
摘要翻译： 本发明提供了识别和编码它们的人类疾病相关蛋白激酶和多核苷酸（统称为DAPK）。 本发明还提供表达载体，宿主细胞，激动剂，抗体和拮抗剂。 本发明还提供用于诊断和治疗与人类疾病相关蛋白激酶的表达相关的疾病的方法。
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公开(公告)号：US5989860A
公开(公告)日：1999-11-23
申请号：US989386
申请日：1997-12-12
CPC分类号： C12N9/90
摘要： The invention provides human isomerase homologs (HIH) and polynucleotides which identify and encode HIH. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for treating or preventing disorders associated with expression of HIH.
摘要翻译： 本发明提供了人异源酶同源物（HIH）和识别和编码HIH的多核苷酸。 本发明还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂。 本发明还提供了治疗或预防与HIH表达相关的病症的方法。
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公开(公告)号：US06558914B1
公开(公告)日：2003-05-06
申请号：US09388995
申请日：1999-09-02
IPC分类号： C12Q148
CPC分类号： C12N9/1029 , A61K38/00
摘要： The invention provides a human lysophosphatidic acid acyltranferase (HLPAAT) and polynucleotides which identify and encode HLPAAT. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for treating or preventing disorders associated with expression of HLPAAT.
摘要翻译： 本发明提供了人溶血磷脂酸酰基转移酶（HLPAAT）和鉴定和编码HLPAAT的多核苷酸。 本发明还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂。 本发明还提供治疗或预防与HLPAAT表达相关的病症的方法。
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