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    Apparatus and method of reacting polymers by exposure to UV radiation to produce injectable medical devices
    31.
    发明授权
    Apparatus and method of reacting polymers by exposure to UV radiation to produce injectable medical devices 有权
    通过暴露于UV辐射使聚合物反应以产生可注射的医疗装置的装置和方法

    公开(公告)号：US09375699B2

    公开(公告)日：2016-06-28

    申请号：US13202345

    申请日：2010-02-22

    Applicant: Sébastien Ladet

    Inventor： Sébastien Ladet

    IPC: A61B17/00 ,  B01J19/12

    CPC classification number: B01J19/123 ,  A61B17/00491 ,  A61B2017/00495 ,  B01J2219/0888

    Abstract: Cross-linked compositions include a first precursor functionalized with a first reactive member and a second precursor functionalized with a second reactive member, the first and second reactive members covalently bonding with each other when exposed to UV radiation. The compositions are useful in a variety of surgical and wound treatment applications.

    Abstract translation: 交联组合物包括用第一反应性成员官能化的第一前体和用第二反应性成员官能化的第二前体，当暴露于UV辐射时，第一和第二反应性成员彼此共价键合。 该组合物可用于各种手术和伤口治疗应用。

    APPARATUS AND METHOD OF REACTING POLYMERS PASSING THROUGH METAL ION CHELATED RESIN MATRIX TO PRODUCE INJECTABLE MEDICAL DEVICES
    37.
    发明申请
    APPARATUS AND METHOD OF REACTING POLYMERS PASSING THROUGH METAL ION CHELATED RESIN MATRIX TO PRODUCE INJECTABLE MEDICAL DEVICES 有权
    通过金属离子螯合树脂基质反应聚合物生产注射用医疗装置的装置和方法

    公开(公告)号：US20120035335A1

    公开(公告)日：2012-02-09

    申请号：US13202348

    申请日：2010-02-22

    Applicant: Sébastien Ladet ,  Philippe Gravagna

    Inventor： Sébastien Ladet ,  Philippe Gravagna

    IPC: A61L24/04 ,  C08G75/04 ,  B01J19/00 ,  C08G63/91 ,  A61L31/06 ,  C08G73/00 ,  C08G75/12 ,  C08G73/02

    CPC classification number: B01J19/18 ,  A61B17/00491 ,  A61B2017/00495 ,  B01F5/0615 ,  B01F5/0683 ,  B01F5/0688 ,  B01F13/002 ,  B01F13/0023 ,  B01J14/005 ,  B01J19/0053 ,  B01J19/0066 ,  B01J23/72 ,  B01J35/04 ,  B01J2219/00761 ,  C08G63/66

    Abstract: The present disclosure relates to an apparatus and process for forming medical devices from an injectable composition. The apparatus includes a supply assembly configured to maintain and selective dispense a first precursor and a second precursor, a mixing assembly configured to mix the first and second precursors, and at least one catalyzing element including a transition metal ion to aid in the polymerization of the first and second precursors. The process includes dispensing a volume of the first precursor and a volume of the second precursor into a mixing assembly and mixing the first and second precursors. The first and second precursors each possess a core and at least one functional group known to have click reactivity with each other. The mixed precursors are contacted with a transition metal catalyst to produce a flowable composition for use as a medical device.

    Abstract translation: 本公开涉及一种用于从可注射组合物形成医疗装置的装置和方法。 该设备包括供应组件，其被配置为维持和选择性地分配第一前体和第二前体，配置成混合第一和第二前体的混合组件和包含过渡金属离子的至少一个催化元素以有助于聚合 第一和第二前体。 该方法包括将体积的第一前体和体积的第二前体分配到混合组件中并混合第一和第二前体。 第一和第二前体各自具有核心和至少一个已知具有彼此具有点击反应性的官能团。 混合的前体与过渡金属催化剂接触以产生用作医疗装置的可流动组合物。

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