公开(公告)号：US09725400B2

公开(公告)日：2017-08-08

申请号：US15219655

申请日：2016-07-26

申请人： Shin-Etsu Chemical Co., Ltd.

发明人： Takeshi Kinsho ,  Naoki Ishibashi ,  Shinnosuke Wakamori ,  Miyoshi Yamashita

IPC分类号： C07C69/587 ,  C07C29/14 ,  C07C29/147 ,  C07C69/08 ,  C07C67/327 ,  C07C67/40 ,  C07C67/08

CPC分类号： C07C69/587 ,  C07C29/14 ,  C07C29/147 ,  C07C67/08 ,  C07C67/327 ,  C07C67/40 ,  C07C69/145 ,  C07C33/02

摘要： Provided is a geometrically selective method for producing (±)-(E)-2-isopropyl-5-methyl-3,5-hexadienyl acetate, which is a sex pheromone of grape pineapple mealybug (GPMB). Specifically provided is a method for producing a an (E)-2-isopropyl-5-methyl-3,5-hexadienyl carboxylate compound (4), the method comprising the steps of: dehydrating a 3-hydroxy-2-isopropyl-5-methyl-4-hexenoate compound (1) to obtain an (E)-2-isopropyl-5-methyl-3,5-hexadienoate compound (2); reducing the alkoxycarbonyl group of the compound (2) to obtain (E)-2-isopropyl-5-methyl-3,5-hexadienol (3); and esterifying the compound (3) to obtain the compound (4).

公开(公告)号：US20160221924A1

公开(公告)日：2016-08-04

申请号：US15021168

申请日：2014-09-11

申请人： SHIN-ETSU CHEMICAL CO., LTD.

发明人： Takeshi Kinsho ,  Naoki Ishibashi

IPC分类号： C07C67/40 ,  C07C41/01 ,  C07C29/14 ,  C07C45/42

CPC分类号： C07C67/40 ,  C07C29/14 ,  C07C41/01 ,  C07C45/42 ,  C07C67/14 ,  C07C2601/16 ,  C07C69/24 ,  C07C33/14 ,  C07C47/42

摘要： Target compounds are synthesized simply, efficiently and selectively. More specifically, provided are a method for producing (2,4,4-trimethyl-1-cyclohexene)carbaldehyde, comprising the steps of: reacting the carbonyl group of 2,4,4-trimethyl-2-cyclohexenone (1) to obtain a 2,4,4-trimethyl-2-cyclohexenylidenemethyl ether compound (2) and hydrolyzing Compound (2) to obtain the (2,4,4-trimethyl-1-cyclohexene)carbaldehyde (3); a method for producing (2,4,4-trimethyl-1-cyclohexene)methanol, comprising a step of reducing Compound (3) to obtain the (2,4,4-trimethyl-1-cyclohexene)methanol (4); and a method for producing a (2,4,4-trimethyl-1-cyclohexenyl)methyl ester compound, comprising a step of esterifying Compound (4) to obtain the (2,4,4-trimethyl-1-cyclohexenyOmethyl ester compound (5).

摘要翻译： 目标化合物被简单，有效和有选择地合成。 更具体地说，提供了制备（2,4,4-三甲基-1-环己烯）甲醛的方法，包括以下步骤：使2,4,4-三甲基-2-环己烯酮（1）的羰基反应得到 2,4,4-三甲基-2-环己烯甲醚化合物（2）和水解化合物（2），得到（2,4,4-三甲基-1-环己烯）甲醛（3）; 制备（2,4,4-三甲基-1-环己烯）甲醇的方法，包括还原化合物（3）以获得（2,4,4-三甲基-1-环己烯）甲醇（4）的步骤; 和（2,4,4-三甲基-1-环己烯基）甲酯化合物的制备方法，其包括使化合物（4）酯化以得到（2,4,4-三甲基-1-环己烯基甲基酯化合物（ 5）。

公开(公告)号：US20160221923A1

公开(公告)日：2016-08-04

申请号：US15021155

申请日：2014-09-11

申请人： SHIN-ETSU CHEMICAL CO., LTD.

发明人： Takeshi Kinsho ,  Naoki Ishibashi

IPC分类号： C07C67/40 ,  C07C1/207 ,  C07C29/03

CPC分类号： C07C67/40 ,  C07C1/207 ,  C07C1/2076 ,  C07C29/03 ,  C07C67/14 ,  C07C2601/16 ,  C07C33/14 ,  C07C69/24 ,  C07C13/20

摘要： A targeted compound is produced simply, efficiently and selectively. Specifically provided are a method for producing (2,4,4-trimethyl-2-cyclohexene)methanol, comprising the steps of: reacting the carbonyl group of 2,4,4-trimethyl-2-cyclohexenone (1) to obtain 1-methylene-2,4,4-trimethyl-2-cyclohexene (2) and reacting the exocyclic double bond of Compound (2) to obtain the (2,4,4-trimethyl-2-cyclohexene)methanol (3); and a method for producing a (2,4,4-trimethyl-2-cyclohexenyl)methyl ester compound, comprising a step of esterifying Compound (3) to obtain the (2,4,4-trimethyl-2-cyclohexenyl)methyl ester compound (4).

摘要翻译： 目标化合物简单，有效和有选择地生产。 具体提供的是制备（2,4,4-三甲基-2-环己烯）甲醇的方法，包括以下步骤：使2,4,4-三甲基-2-环己烯酮（1）的羰基反应，得到1- 亚甲基-2,4,4-三甲基-2-环己烯（2），并使化合物（2）的环外双键反应得到（2,4,4-三甲基-2-环己烯）甲醇（3）; 和（2,4,4-三甲基-2-环己烯基）甲酯化合物的制造方法，包括使化合物（3）酯化以得到（2,4,4-三甲基-2-环己烯基）甲酯的步骤 化合物（4）。

公开(公告)号：US20160185708A1

公开(公告)日：2016-06-30

申请号：US14974052

申请日：2015-12-18

申请人： Shin-Etsu Chemical Co., Ltd.

发明人： Takeshi Kinsho ,  Naoki Ishibashi ,  Yusuke Nagae

IPC分类号： C07C69/65 ,  C07C317/14 ,  C07C317/04 ,  C07C315/04 ,  C07C67/297

CPC分类号： C07C309/66 ,  C07C67/287 ,  C07C67/293 ,  C07C67/297 ,  C07C69/63 ,  C07C69/65 ,  C07C309/73 ,  C07C315/04 ,  C07C317/04 ,  C07C317/14 ,  C07C2601/02 ,  C07C69/24 ,  C07C69/145

摘要： Provided is a simple, selective and efficient method for producing 4-alkyl-3-methylenebutyl carboxylates such as 7-methyl-3-methylene-7-octenyl propionate. More specifically, provided is, for example, a method for producing a 4-alkyl-3-methylenebutyl carboxylate compound, comprising an acyloxylation step of subjecting a 1-(2-haloethyl)cyclopropyl sulfonate compound (1) to acyloxylation to obtain a 1-(2-acyloxyethyl)cyclopropyl sulfonate compound (2), a halogenation step of subjecting the compound (2) to halogenation involving cyclopropyl-allyl rearrangement to obtain a 3-halomethyl-3-butenyl carboxylate compound (3), and a coupling step of subjecting the compound (3) to a coupling reaction with an organometallic reagent (4) to obtain the 4-alkyl-3-methylenebutyl carboxylate compound (5).

摘要翻译： 提供了一种用于制备4-烷基-3-亚甲基丁基羧酸酯如7-甲基-3-亚甲基-7-辛烯基丙酸酯的简单，选择性和有效的方法。 更具体地，例如，提供了一种4-烷基-3-亚甲基丁基羧酸酯化合物的制造方法，其包括使1-（2-卤代乙基）环丙基磺酸酯化合物（1）进行酰氧基化获得1的酰氧基化步骤 - （2-酰氧基乙基）环丙基磺酸酯化合物（2），使化合物（2）进行涉及环丙基 - 烯丙基重排的卤化反应得到3-卤代甲基-3-丁烯基羧酸酯化合物（3）的卤化步骤，以及偶联步骤 使化合物（3）与有机金属试剂（4）进行偶联反应，得到4-烷基-3-亚甲基丁基羧酸酯化合物（5）。

公开(公告)号：US20160185690A1

公开(公告)日：2016-06-30

申请号：US14974027

申请日：2015-12-18

申请人： Shin-Etsu Chemical Co., Ltd.

发明人： Takeshi Kinsho ,  Naoki Ishibashi ,  Yoshiyuki Yumoto

IPC分类号： C07C17/263 ,  C07C21/19 ,  C07C67/10

CPC分类号： C07C17/2632 ,  C07C17/208 ,  C07C21/19 ,  C07C67/10 ,  C07C67/11 ,  C07C69/24

摘要： Provided is a simple, selective and efficient method for producing 7-methyl-3-methylene-7-octenyl propionate and the like. More specifically, provided is, for example, a method for producing 7-methyl-3-methylene-7-octenyl propionate, comprising the steps of: subjecting a nucleophile represented by Formula (1) and an electrophile represented by Formula (2) to a coupling reaction to obtain a 7-methyl-3-methylene-7-octenyl halide represented by Formula (3), and subjecting the 7-methyl-3-methylene-7-octenyl halide (3) to propionyloxylation to obtain the 7-methyl-3-methylene-7-octenyl propionate represented by Formula (4).

摘要翻译： 提供了一种用于制备丙酸7-甲基-3-亚甲基-7-辛烯酯等的简单，选择和有效的方法。 更具体地，例如提供了7-甲基-3-亚甲基-7-辛烯基丙酸酯的制备方法，包括以下步骤：将式（1）表示的亲核试剂和由式（2）表示的亲电子试剂 得到由式（3）表示的7-甲基-3-亚甲基-7-辛烯基卤化物的偶联反应，并将7-甲基-3-亚甲基-7-辛烯基卤化物（3）进行丙酰氧基化，得到7- 由式（4）表示的3-甲基-3-亚甲基-7-辛烯基丙酸酯。

公开(公告)号：US09278899B2

公开(公告)日：2016-03-08

申请号：US14713582

申请日：2015-05-15

申请人： Shin-Etsu Chemical Co., Ltd.

发明人： Akihiro Baba ,  Takeshi Kinsho ,  Naoki Ishibashi

IPC分类号： C07C51/36 ,  C07C51/373 ,  C07C51/09 ,  C07C51/38 ,  C07C57/13

CPC分类号： C07C51/36 ,  C07C51/09 ,  C07C51/373 ,  C07C51/38 ,  C07C57/13 ,  C07C57/03 ,  C07C53/126

摘要： Provided is a process for producing 3,5-dimethyldodecanoic acid, which is an active ingredient of the pheromone of California prionus, and 4-carboxy-3,5-dimethyl-3,5-dodecadienoic acid which is an intermediate useful for producing 3,5-dimethyldodecanoic acid. More specifically, provided is a method for producing 3,5-dimethyldodecanoic acid, comprising the steps of subjecting 3-methyl-2-pentene-1,5-diacid diester (1) and 2-nonanone (2) to a condensation reaction and subsequent hydrolysis into 4-carboxy-3,5-dimethyl-3,5-dodecadienoic acid (3); decarboxylating or decarboxylating and hydrolyzing the 4-carboxy-3,5-dimethyl-3,5-dodecadienoic acid (3) into 3,5-dimethyl-2,4-dodecadienoic acid (4); and hydrogenating the 3,5-dimethyl-2,4-dodecadienoic acid (4) into 3,5-dimethyldodecanoic acid (5), as shown in the following scheme:

摘要翻译： 提供了作为加利福尼亚朊病毒的信息素的活性成分的3,5-二甲基十二烷酸的制造方法和作为生产3的中间体的4-羧基-3,5-二甲基-3,5-癸二烯酸 ，5-二甲基十二烷酸。 更具体地说，提供了一种3,5-二甲基十二烷酸的制造方法，其特征在于，包括使3-甲基-2-戊烯-1,5-二酸二酯（1）和2-壬酮（2）进行缩合反应的工序， 随后水解成4-羧基-3,5-二甲基-3,5-二十二碳烯酸（3）; 脱羧或脱羧并将4-羧基-3,5-二甲基-3,5-二十二碳烯酸（3）水解成3,5-二甲基-2,4-十二碳二烯酸（4）; 并将3,5-二甲基-2,4-十二碳二烯酸（4）氢化成3,5-二甲基十二烷酸（5），如下列方案所示：

公开(公告)号：US12013639B2

公开(公告)日：2024-06-18

申请号：US17376394

申请日：2021-07-15

申请人： SHIN-ETSU CHEMICAL CO., LTD.

发明人： Jun Hatakeyama ,  Naoki Ishibashi ,  Masayoshi Sagehashi

IPC分类号： G03F7/039 ,  G03F7/004 ,  G03F7/20

CPC分类号： G03F7/0397 ,  G03F7/0045 ,  G03F7/2006

摘要： A positive resist material contains a base polymer containing: a repeating unit having two carboxyl groups whose hydrogen atoms are substituted with two tertiary carbon atoms each bonded to a double bond or triple bond; and a repeating unit having an acid generator shown by any of the following formulae (b1) to (b3). Thus, the present invention provides: a positive resist material having higher sensitivity than conventional positive resist materials, and smaller dimensional variation; and a patterning process using this inventive positive resist material.

公开(公告)号：US11097999B2

公开(公告)日：2021-08-24

申请号：US17010236

申请日：2020-09-02

申请人： Shin-Etsu Chemical Co., Ltd.

发明人： Yuki Miyake ,  Naoki Ishibashi ,  Takeshi Kinsho

IPC分类号： C07C45/42 ,  C07C47/20

摘要： A process for preparing 4-penten-2-ynal of the following formula (2): CH2═CHC≡CCHO  (2) the process comprising a step of hydrolyzing a 5,5-dialkoxy-1-penten-3-yne compound of the following general formula (1): CH2═CHC≡CCH(OR1)(OR2)  (1) wherein R1 and R2 represent, independently of each other, a monovalent hydrocarbon group having 1 to 15 carbon atoms, preferably 1 to 8, more preferably 1 to 4, or R1 and R2 may be bonded to each other to form a divalent hydrocarbon group, R1-R2, having from 2 to 10 carbon atoms, to obtain 4-penten-2-ynal (2).

公开(公告)号：US20210017112A1

公开(公告)日：2021-01-21

申请号：US16930570

申请日：2020-07-16

申请人： Shin-Etsu Chemical Co., Ltd.

发明人： Naoki Ishibashi ,  Yusuke Nagae ,  Takeshi Kinsho

IPC分类号： C07C45/62

摘要： The present invention provides a process for preparing a dimethylcyclobutane compound of the following general formula (1A), the process comprising reacting a dimethylcyclobutanone compound of the following general formula (2) with a phosphonic ester compound of the following general formula (3) to produce an unsaturated ester compound of the following general formula (4), having a dimethylcyclobutane ring, and subjecting the unsaturated ester compound (4), having a dimethylcyclobutane ring, to a reduction reaction to produce the dimethylcyclobutane compound (1A).

公开(公告)号：US10244750B2

公开(公告)日：2019-04-02

申请号：US14362242

申请日：2012-12-06

申请人： SHIN-ETSU CHEMICAL CO., LTD.

发明人： Naoki Ishibashi ,  Ryuichi Saguchi ,  Tatsuya Hojo ,  Takehiko Fukumoto

IPC分类号： A01N25/04 ,  A01N25/34 ,  A01N31/02 ,  A01N35/02 ,  A01N37/06 ,  A01N43/90 ,  A01N25/18

摘要： Provided are an insect pest-targeting gel composition causing neither leakage nor reaction of a volatile substance and capable of releasing the volatile substance at a constant rate; and a sustained release preparation including the insect pest-targeting gel composition. More specifically, provided is an insect pest-targeting gel composition including one or more volatile substances and an oil gelling agent, wherein the volatile substance is included in an amount of from 70.0 to 99.0% by weight by the insect pest-targeting gel composition.