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38 条记录 (耗时 0.045 秒)

    Method and apparatus for predicting deterioration of a member constituting a part of equipment
    33.
    发明授权
    Method and apparatus for predicting deterioration of a member constituting a part of equipment 失效
    用于预测构成设备的一部分的部件的劣化的方法和装置

    公开(公告)号：US4987367A

    公开(公告)日：1991-01-22

    申请号：US406366

    申请日：1989-09-12

    申请人： Yuichi Ishikawa ,  Toshihiko Yoshimura ,  Tasuku Shimizu ,  Masahiro Otaka ,  Kazuo Takaku

    发明人： Yuichi Ishikawa ,  Toshihiko Yoshimura ,  Tasuku Shimizu ,  Masahiro Otaka ,  Kazuo Takaku

    IPC分类号： B24B27/033 ,  G01N1/04 ,  G01N1/28 ,  G01N27/00 ,  G01N27/72 ,  G01Q20/00 ,  G07C3/00 ,  G21C13/087 ,  G21C17/00

    CPC分类号： G21C13/087 ,  G01N27/72 ,  G07C3/00 ,  G21C17/00 ,  Y02E30/40

    摘要： Measurement of a physical property such as coercive force of a member to be inspected is performed at a plurality of locations in one region of the member. Similar measurement is performed in a plurality of different regions of the member and a maximum or minimum value (extreme value) is determined for each of the regions. On the basis of the extreme values thus determined, a recurrence period is determined in accordance with an extreme value statistic theory with the aid of a computer, whereon an estimated maximum value of the physical property of the member as a whole is determined from the recurrence period. On the basis of the estimated maximum value, the degree of deterioration of the member is predicted by the computer by consulting the data indicating the previously determined relation between the physical property and the degree of deterioration.

    摘要翻译： 在被检查部件的一个区域中的多个位置处进行诸如被检查部件的矫顽力的物理性能的测量。 在成员的多个不同区域中执行类似的测量，并且为每个区域确定最大值或最小值（极值）。 根据这样确定的极值，根据极值统计理论借助于计算机确定复发周期，从计算机估计整体成员的物理财产的最大值，从复发确定 期。 基于估计的最大值，通过咨询表示先前确定的物理性质和劣化程度的关系的数据，由计算机预测成员的劣化程度。

    Acylamide compounds having secretagogue or inducer activity of adiponectin
    34.
    发明授权
    Acylamide compounds having secretagogue or inducer activity of adiponectin 失效
    具有促分泌素或脂联素诱导活性的酰胺化合物

    公开(公告)号：US07732637B2

    公开(公告)日：2010-06-08

    申请号：US11835029

    申请日：2007-08-07

    申请人： Katsumi Maezono ,  Toshihiko Yoshimura ,  Nozomu Ishida ,  Naoyuki Fukuchi ,  Toshihiro Hatanaka ,  Osamu Ikehara ,  Yayoi Kawato ,  Hideyuki Tanaka

    发明人： Katsumi Maezono ,  Toshihiko Yoshimura ,  Nozomu Ishida ,  Naoyuki Fukuchi ,  Toshihiro Hatanaka ,  Osamu Ikehara ,  Yayoi Kawato ,  Hideyuki Tanaka

    IPC分类号： C07C229/06 ,  A61K31/20

    CPC分类号： C07C233/47 ,  A23L33/10 ,  C07C323/59

    摘要： The present invention provides an acylamide compound of the following formula (1), prodrugs thereof, or pharmaceutically acceptable salts thereof; and an adiponectin inducer or secretagogue, therapeutic agent of metabolic syndromes, therapeutic agent of hypoadiponectinemia, therapeutic agent of hyperlipemia, preventive/therapeutic agent of diabetes, improving agent of impaired glucose tolerance, improving agent of insulin resistance, enhancing agent of insulin sensitivity, therapeutic agent of hypertension, preventive/therapeutic agent of vascular disorders, an anti-inflammatory agent, therapeutic agent of hepatic inflammation, therapeutic agent of fatty liver, therapeutic agent of hepatic fibrosis, therapeutic agent of liver cirrhosis, preventive/therapeutic agent of non-alcoholic/nonviral steatohepatitis (NASH) or non-alcoholic/nonviral fatty liver disease (NAFLD), or therapeutic agent of obesity, each of which has the above compounds as an active ingredient.

    摘要翻译： 本发明提供下式（1）的酰胺化合物，其前体药物或其药学上可接受的盐; 和脂联素诱导剂或促分泌素，代谢综合征的治疗剂，低脂联素血症的治疗剂，高脂血症的治疗剂，糖尿病的预防/治疗剂，葡萄糖耐量降低的改善剂，胰岛素抵抗的改善剂，胰岛素敏感性的增强剂，治疗 高血压药物，血管疾病的预防/治疗剂，抗炎剂，肝脏炎症治疗剂，脂肪肝治疗剂，肝纤维化治疗剂，肝硬化治疗剂，非酒精性预防/治疗剂 /非病毒性脂肪性肝炎（NASH）或非酒精性/非病毒性脂肪性肝病（NAFLD）或肥胖症治疗剂，其各自具有上述化合物作为活性成分。

    Vehicular remote control system and tire pressure monitoring system
    35.
    发明授权
    Vehicular remote control system and tire pressure monitoring system 失效
    车载遥控系统和轮胎压力监测系统

    公开(公告)号：US07181189B2

    公开(公告)日：2007-02-20

    申请号：US11021727

    申请日：2004-12-23

    申请人： Shinji Hotta ,  Toshihiko Yoshimura

    发明人： Shinji Hotta ,  Toshihiko Yoshimura

    IPC分类号： H04B1/16 ,  B60C23/00 ,  B60C23/02 ,  B60C1/00

    CPC分类号： G07C9/00309 ,  B60C23/0416 ,  B60C23/0433 ,  B60C23/0462 ,  B60R25/246 ,  G07C2009/00793 ,  G07C2209/63

    摘要： A vehicular remote control system has a mobile unit, a vehicle unit for establishing bidirectional wireless communication with the mobile unit, wherein the vehicle unit is able to transmit a wireless signal to the mobile unit through transmission antennas provided at a plurality of positions of a vehicle, and operational intention detector, provided at the plurality of positions of the vehicle corresponding to the transmission antennas, for detecting operational intention of a user approaching the positions. When a user's operational intention is detected, a predetermined request signal is transmitted from the vehicle unit to the mobile unit through a first transmission antenna, and the vehicle unit transmits an interrupt signal for preventing reception of the request signal, through a second transmission antenna.

    摘要翻译： 车辆遥控系统具有移动单元，用于与移动单元建立双向无线通信的车辆单元，其中车辆单元能够通过设置在车辆的多个位置处的发送天线向移动单元发送无线信号 以及设置在与发送天线对应的车辆的多个位置的操作意图检测器，用于检测接近位置的用户的操作意图。 当检测到用户的操作意图时，通过第一发送天线将预定请求信号从车辆单元发送到移动单元，并且车辆单元通过第二发送天线发送用于防止接收请求信号的中断信号。

    PPAR ACTIVITY REGULATORS
    36.
    发明申请
    PPAR ACTIVITY REGULATORS 失效
    PPAR活性调节剂

    公开(公告)号：US20070276041A1

    公开(公告)日：2007-11-29

    申请号：US11753967

    申请日：2007-05-25

    申请人： Akiko Oonuki ,  Toshihiko Yoshimura ,  Katsumi Maezono ,  Yayoi Kawato ,  Hideyuki Tanaka ,  Naoyuki Fukuchi ,  Nozomu Ishida

    发明人： Akiko Oonuki ,  Toshihiko Yoshimura ,  Katsumi Maezono ,  Yayoi Kawato ,  Hideyuki Tanaka ,  Naoyuki Fukuchi ,  Nozomu Ishida

    IPC分类号： A61K31/198 ,  C07C235/04

    CPC分类号： C07C233/47 ,  C07C233/49 ,  C07C233/52 ,  C07C2601/14

    摘要： The object of the present invention is to provide PPAR (peroxisome proliferator-activated receptor) activity regulators, which can be widely used for improving insulin resistance and preventing/treating various diseases such as diabetes, metabolic syndromes, hyperlipemia, high-blood pressure, vascular disorders, inflammation, hepatitis, fatty liver, liver fibrosis, NASH (non-alcoholic steatohepatitis) and obesity.The present invention provides PPAR activity regulators which comprise an acylamide compound having the specific structure, prodrugs thereof, or pharmaceutically acceptable salts thereof.

    摘要翻译： 本发明的目的是提供PPAR（过氧化物酶体增殖物激活受体）活性调节剂，其可广泛用于改善胰岛素抵抗和预防/治疗各种疾病如糖尿病，代谢综合征，高脂血症，高血压，血管 疾病，炎症，肝炎，脂肪肝，肝纤维化，NASH（非酒精性脂肪性肝炎）和肥胖症。 本发明提供了包含具有特定结构的酰基酰胺化合物，其前药或其药学上可接受的盐的PPAR活性调节剂。