公开(公告)号：US5126437A

公开(公告)日：1992-06-30

申请号：US362902

申请日：1989-06-07

申请人： Lutz-F. Tietze ,  Manfred Neumann ,  Roland Fischer

发明人： Lutz-F. Tietze ,  Manfred Neumann ,  Roland Fischer

IPC分类号： A61K31/70 ,  A61K31/7028 ,  A61P35/00 ,  C07H15/04

CPC分类号： C07H15/04

摘要： Compounds of the formula ##STR1## in which R.sup.1 represents saturated, unsaturated or anhydro desoxypentosyl, desoxyhexosyl or didesoxyhexosyl, where the OH functions of the sugar are optionally protected, andR.sup.2 represents straight-chain or branched or heterosubstituted alkyl having up to ten carbon atoms andR.sup.3 represents straight-chain or branched or heterosubstituted alkyl having up to ten carbon atoms andX represents halogens andR.sup.4 represents straight-chain or branched or heterosubstituted alkyl having up to ten carbon atoms.Such compounds are useful as highly selective cytostatics in cancer therapy.

摘要翻译： 其中R1表示饱和，不饱和或脱水脱氧素，脱氧己糖基或二氧代己糖基，其中糖的OH官能团任选被保护，并且R 2表示直链的化合物 具有至多10个碳原子的链或支链或杂取代的烷基，R 3表示具有至多10个碳原子的直链或支链或杂取代的烷基，X表示卤素，R4表示直链或支链或含有至多10个碳原子的支链或杂取代的烷基 原子 这些化合物可用作癌症治疗中的高选择性细胞抑制剂。

公开(公告)号：US4302333A

公开(公告)日：1981-11-24

申请号：US904885

申请日：1978-05-11

申请人： Klaus Cosack ,  Wolfgang Hein ,  Manfred Neumann

发明人： Klaus Cosack ,  Wolfgang Hein ,  Manfred Neumann

IPC分类号： B01D29/00 ,  B01D29/05 ,  B01D29/13 ,  B01D39/10 ,  B01D65/00 ,  B01D35/00

CPC分类号： B01D39/10 ,  B01D35/28 ,  B01D61/10 ,  B01D63/08 ,  B01D2313/90

摘要： A backpressure grid plate is provided for a pressure filtration system of the type comprising a housing with an inlet and outlet for conducting fluid to be treated, a filter disposed in the housing between said inlet and outlet, and a backpressure grid means arranged between the filter and the inlet. The backpressure grid means comprises a plate containing minute openings which are equal in size and distributed unevenly over the surface area of the plate in such manner that the surface distribution density of the openings is lowest within an inner impact area of the plate which receives inflowing fluid to be filtered and is highest within a proximity area of the plate located immediately adjacent to and surrounding the impact area. The surface distribution density of the openings within an outer area surrounding the proximity area is lower than that of the proximity area and higher than that of the impact area.

摘要翻译： 提供了一种用于压力过滤系统的背压格栅板，该压力过滤系统包括具有用于导入待处理流体的入口和出口的壳体，设置在所述入口和出口之间的壳体中的过滤器和布置在过滤器之间的背压格栅装置 和入口。 背压格栅装置包括一个包含微小开口的板，其尺寸相等并且分布在板的表面积不均匀上，使得开口的表面分布密度在接收流入流体的板的内部冲击区域内最低 被过滤并且在紧邻和围绕冲击区域的板的邻近区域内是最高的。 在靠近区域周围的外部区域内的开口的表面分布密度低于接近区域的开口表面分布密度，并且高于冲击区域的表面分布密度。

公开(公告)号：US09617245B2

公开(公告)日：2017-04-11

申请号：US15003978

申请日：2016-01-22

申请人： Jochen Niemeyer ,  Benjamin Willy ,  Felix Nissen ,  Manfred Neumann ,  Guenter Kreilkamp ,  Sabine Schering

发明人： Jochen Niemeyer ,  Benjamin Willy ,  Felix Nissen ,  Manfred Neumann ,  Guenter Kreilkamp ,  Sabine Schering

IPC分类号： C07D401/14 ,  C07D211/74 ,  C07D211/58 ,  C07D211/46

CPC分类号： C07D401/14 ,  C07D211/46 ,  C07D211/58 ,  C07D211/74

摘要： An N-methyl-substituted triacetonamine compound is prepared by reacting at least one triacetonamine compound (I) with formaldehyde under reductive conditions, in the presence of hydrogen and in the presence of a supported catalyst, wherein the supported catalyst contains at least one metal M, wherein the metal M is selected from the group consisting of V, Cr, Mo, Mn, Ni, Pd, Pt, Fe, Ru, Os, Co, Rh, Ir, and Cu.

公开(公告)号：US08483855B2

公开(公告)日：2013-07-09

申请号：US12725639

申请日：2010-03-17

申请人： Jorg Schrepfer ,  Alexander Mainz ,  Manfred Neumann

发明人： Jorg Schrepfer ,  Alexander Mainz ,  Manfred Neumann

IPC分类号： G06F17/00

CPC分类号： G11B20/10527 ,  G11B2020/10546 ,  G11B2020/10703 ,  G11B2020/10759 ,  G11B2020/10805 ,  H04L69/28 ,  H04R3/00 ,  H04R2499/13

摘要： A method and a device for the playback of digitalized audio signals that are transmitted packet-oriented from a signal source to at least one signal sink, especially a loudspeaker unit, in a motor vehicle by means of an asynchronous bus system. Connected upstream of the signal sink is an audio-signal processing unit demonstrating a data rate converter, which is fed the digitalized audio signals destined for the signal sink from a control unit over a data line by means of a first data interface of the control unit. The control unit has a second data interface for the connection to the asynchronous bus system and for receiving the digitalized audio signals. A data buffer and a controller are arranged within the control unit. A first and second clocking signal provide the clock rates for the first interface and the data rate converter. These clock rates can be changed by a logic unit.

摘要翻译： 一种用于通过异步总线系统在机动车辆中从信号源向数据包定向发送到数字音频信号的方法和装置，其中至少一个信号宿特别是扬声器单元。 在信号接收器的上游连接的是音频信号处理单元，其演示数据速率转换器，其通过控制单元的第一数据接口通过数据线从控制单元馈送去往信号宿的数字化音频信号 。 控制单元具有用于连接到异步总线系统并用于接收数字化音频信号的第二数据接口。 数据缓冲器和控制器布置在控制单元内。 第一和第二时钟信号为第一接口和数据速率转换器提供时钟速率。 这些时钟速率可以由逻辑单元改变。

公开(公告)号：US20120038294A1

公开(公告)日：2012-02-16

申请号：US13266036

申请日：2010-04-23

申请人： Alexander Schulz ,  Michael Wehse ,  Johann Wassermann ,  Manfred Neumann

发明人： Alexander Schulz ,  Michael Wehse ,  Johann Wassermann ,  Manfred Neumann

IPC分类号： H02P5/00 ,  G05B13/00 ,  G05B11/00 ,  H01F7/08 ,  H02K7/09

CPC分类号： G05B13/021 ,  F16C32/0457 ,  F16C32/0474 ,  G05B11/00 ,  H02K7/09

摘要： What is described is an actuator system (2) comprising at least one actuator (29, 29′) and an associated control system (8) which is designed for at least two operating modes, at least one of which may be deactivated, whereby one of the operating modes is a high efficiency operating mode.

摘要翻译： 所描述的是致动器系统（2），其包括至少一个致动器（29,29'）和相关联的控制系统（8），其被设计用于至少两个操作模式，其中至少一个可以被去激活，由此一个 的操作模式是高效率的操作模式。

公开(公告)号：US08011372B2

公开(公告)日：2011-09-06

申请号：US12081552

申请日：2008-04-17

申请人： Manfred Neumann ,  Volker Schmidt

发明人： Manfred Neumann ,  Volker Schmidt

IPC分类号： A24C5/001

CPC分类号： A24C5/42

摘要： A device for filling cigarette tubes with tobacco, wherein the device comprises at least one separating means adapted to detach a tobacco portion from a tobacco block and at least one portioning means adapted to portion the tobacco block, at least one transport means adapted to transport the tobacco block towards the separating means, wherein the portioning means and the transport means are coupled such that the transport means transports the tobacco block in a number of transport steps, and at least one filling means adapted to fill a cigarette tube with the detached tobacco portion. The device further comprises at least one blocking means adapted to block the transport means after each transport step until the at least one filling means has been operated.

摘要翻译： 一种用于用烟草填充香烟管的装置，其中所述装置包括适于将烟草部分从烟草块分离的至少一个分离装置和适于分配烟草块的至少一个分配装置，至少一个运送装置， 烟草块朝向分离装置，其中分配装置和运输装置联接，使得运输装置在多个运输步骤中运输烟草块，并且至少一个填充装置适于用分离的烟草部分填充香烟管 。 所述装置还包括至少一个阻挡装置，其适于在每个输送步骤之后阻挡所述输送装置，直到所述至少一个填充装置已被操作。

公开(公告)号：US20110044762A1

公开(公告)日：2011-02-24

申请号：US12850181

申请日：2010-08-04

申请人： Dietmar Jenne ,  Manfred Neumann

发明人： Dietmar Jenne ,  Manfred Neumann

IPC分类号： F16L1/028 ,  E21B7/20 ,  F16L1/036

CPC分类号： F16L55/1658

摘要： In a method and a device for moving a working means in the ground, a coupling means rotatable about an axis of rotation for establishing a drive connection between a push-pull unit and a rod assembly having at least one projection and/or at least one recess is engaged with the projection and/or the recess of the rod assembly such that via a first contact area of the coupling means a first feed force is transmitted from the push-pull unit to the rod assembly. By the counter force opposite to the first feed force a torque acting on the coupling means is generated, which torque presses a second contact area of the coupling means against the rod assembly with a contact force. By the contact force, a non-positive connection is established between the push-pull unit and the rod assembly. Via this non-positive connection, a second feed force is transmitted to the rod assembly. By at least a part of the first and second feed force acting on the rod assembly a linear movement of the rod assembly is caused.

摘要翻译： 在用于将工作装置移动到地面中的方法和装置中，耦合装置可围绕旋转轴线旋转，以便在推挽单元和具有至少一个突出部的杆组件之间建立驱动连接，和/或至少一个 凹部与杆组件的突起和/或凹部接合，使得经由联接装置的第一接触区域，第一进给力从推拉单元传递到杆组件。 通过与第一进给力相反的反作用力，产生作用在联接装置上的扭矩，哪个扭矩以接触力将联接装置的第二接触区域压靠在杆组件上。 通过接触力，在推挽单元和杆组件之间建立非正连接。 通过该非正向连接，第二进给力传递到杆组件。 通过作用在杆组件上的第一和第二进给力的至少一部分引起杆组件的线性运动。

公开(公告)号：US07803255B2

公开(公告)日：2010-09-28

申请号：US10480791

申请日：2002-06-13

申请人： Manfred Neumann ,  Steffen Straach ,  Mario Krug ,  Nicolas Schiller

发明人： Manfred Neumann ,  Steffen Straach ,  Mario Krug ,  Nicolas Schiller

IPC分类号： C23C14/34 ,  C23C16/00

CPC分类号： H01J37/32422 ,  C23C14/32 ,  C23C14/56

摘要： The invention relates to a device for the plasma activated vapor coating of large-surface moved substrates, comprising at least one vacuum recipient, one pump system, one evaporator, one device for holding and transporting the substrates to be coated and at least one arc discharge plasma source, whereby at least one device for generating a magnetic field is included, which device can generate a magnetic field between the evaporator and the substrate, the field lines of which magnetic field are aligned approximately perpendicular to the movement direction and parallel to the transport plane of the substrate, and at least one arc discharge plasma source is arranged such that the axis of the arc discharge plasma source is aligned approximately perpendicular to the field lines of the magnetic field.

摘要翻译： 本发明涉及一种用于大面积移动的基板的等离子体活化蒸气涂层的装置，包括至少一个真空接收器，一个泵系统，一个蒸发器，一个用于保持和输送待涂覆的基板的装置和至少一个电弧放电 等离子体源，由此包括用于产生磁场的至少一个装置，该装置可以在蒸发器和基板之间产生磁场，其中磁场线大致垂直于运动方向排列并平行于运送 平面，并且布置至少一个电弧放电等离子体源，使得电弧放电等离子体源的轴线大致垂直于磁场的场线排列。

公开(公告)号：US07700805B2

公开(公告)日：2010-04-20

申请号：US12118884

申请日：2008-05-12

申请人： Günther Köhler ,  Manfred Neumann ,  Marianne Omeis

发明人： Günther Köhler ,  Manfred Neumann ,  Marianne Omeis

IPC分类号： C07C209/62

CPC分类号： C07C209/62 ,  C07C211/12

摘要： An amine is prepared by cleaving a carbamate of the formula I wherein R1=hydrogen, alkyl, aryl or phenyl group, R2=alkyl, aryl or phenyl group, wherein R1 and R2 are independently substituted or unsubstituted, wherein the cleaving of the carbamate is performed in the presence of an acid of the formula II wherein R3, R4 and R5 are independently alkyl or phenyl group, wherein R1, R2, R3, R4 and R5 are the same or different.

摘要翻译： 通过切割式I的氨基甲酸酯制备胺，其中R1 =氢，烷基，芳基或苯基，R2 =烷基，芳基或苯基，其中R1和R2独立地被取代或未取代，其中氨基甲酸酯的裂解是 在式II的酸存在下进行，其中R 3，R 4和R 5独立地为烷基或苯基，其中R 1，R 2，R 3，R 4和R 5相同或不同。

公开(公告)号：US20100076186A1

公开(公告)日：2010-03-25

申请号：US12564509

申请日：2009-09-22

申请人： Thomas KUEBELBAECK ,  Manfred Neumann ,  Marianne Omeis

发明人： Thomas KUEBELBAECK ,  Manfred Neumann ,  Marianne Omeis

IPC分类号： C07D413/02

CPC分类号： C07D263/10 ,  Y02P20/582

摘要： Provided is a process for preparing a heterocycle by catalytic reaction of an aromatic dinitrile with an amino alcohol, wherein the process includes: initially charging into a reaction vessel the amino alcohol and a catalyst to produce a reaction mixture; adding the aromatic dinitrile into the reaction mixture, which is maintained at a reaction temperature, wherein no solvent other than the amino alcohol of formula (III) is added to the reaction mixture prior to and/or during the catalytic reaction; and after completion of the catalytic reaction, completely replacing, or substantially completely replacing, unreacted amino alcohol with a nonpolar solvent to obtain the heterocycle, wherein the unreacted amino alcohol is present in an amount of not more than 20 wt. %, preferably 3-10 wt. % or less, based on a total weight of the heterocycle.

摘要翻译： 提供了通过芳族二腈与氨基醇的催化反应制备杂环的方法，其中该方法包括：首先将氨基醇和催化剂装入反应容器中以产生反应混合物; 将芳族二腈加入反应混合物中，其保持在反应温度下，其中在催化反应之前和/或催化反应期间，将不超过式（III）的氨基醇的溶剂加入到反应混合物中; 并且在催化反应完成后，用非极性溶剂完全替代或基本上完全替代未反应的氨基醇，得到杂环，其中未反应的氨基醇的存在量不超过20wt。 ％，优选3-10wt。 ％以下，基于杂环的总重量。