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38 条记录 (耗时 0.032 秒)

    Peripheral seal for a ventricular partitioning device
    32.
    发明申请
    Peripheral seal for a ventricular partitioning device 有权
    心室分隔装置的外围密封

    公开(公告)号：US20060281965A1

    公开(公告)日：2006-12-14

    申请号：US11151164

    申请日：2005-06-10

    申请人： Alexander Khairkhahan ,  Hugh Sharkey ,  Serjan Nikolic ,  Branislav Radovancevic

    发明人： Alexander Khairkhahan ,  Hugh Sharkey ,  Serjan Nikolic ,  Branislav Radovancevic

    IPC分类号： A61F2/00

    CPC分类号： A61B17/12022 ,  A61B17/12122 ,  A61B17/12172 ,  A61B17/1219 ,  A61B2017/00243 ,  A61B2017/12095 ,  A61B2017/22061

    摘要： This invention is directed to a partitioning device for separating a patient's heart chamber into a productive portion and a non-productive portion which is suitable for treating patients with heart disease, particularly congestive heart failure. The partitioning device has a reinforced membrane with outwardly biased members to help seal the periphery of the membrane against the wall of the patient's heart chamber. In one embodiment, the outwardly biased member is an expansive strand that extends between adjacent ribs of an expandable frame which reinforces the membrane. In another embodiment, the outwardly biased member is a hydrophilic body such as foam which swells upon contact with body fluid such as blood in the heart chamber. The reinforced membrane has a central hub with a distally extending support stem with a plurality of feet which extend radially from a centerline axis and preferably have ends that are aligned in a common plane. The ends of the pods which extend radially away from the centerline axis may be interconnected by flexible struts and/or webs.

    摘要翻译： 本发明涉及一种用于将患者心室分离成生产部分和非生产性部分的分隔装置，其适用于治疗患有心脏病，特别是充血性心力衰竭的患者。 分隔装置具有增强的膜，其具有向外偏置的构件，以帮助将膜的周边密封抵靠患者心室的壁。 在一个实施例中，向外偏置的构件是在可扩展框架的相邻肋之间延伸的膨胀股线，其可加强膜。 在另一个实施方案中，向外偏压的构件是亲水体，例如泡沫，当与心液室中的体液如血液接触时膨胀。 加强膜具有中心毂，其具有远端延伸的支撑杆，多个脚从中心线径向延伸，并且优选地具有在公共平面中对准的端部。 从径向远离中心线轴线延伸的荚的端部可通过柔性支柱和/或腹板相互连接。

    Ventricular partitioning device
    34.
    发明申请
    Ventricular partitioning device 审中-公开
    心室分配装置

    公开(公告)号：US20060030881A1

    公开(公告)日：2006-02-09

    申请号：US10913608

    申请日：2004-08-05

    申请人： Hugh Sharkey ,  Alexander Khairkhkahan ,  Serjan Nikolic ,  Branislav Radovancevic

    发明人： Hugh Sharkey ,  Alexander Khairkhkahan ,  Serjan Nikolic ,  Branislav Radovancevic

    IPC分类号： A61B17/08

    CPC分类号： A61B17/12172 ,  A61B17/12122 ,  A61B2017/00526 ,  A61B2017/12095

    摘要： This invention is directed to a partitioning device for separating a patient's heart chamber into a productive portion and a non-productive portion. The device is particularly suitable for treating patients with congestive heart failure. The partitioning device has a frame-reinforced, expandable membrane which separates the productive and non-productive portions of the heart chamber. The proximal ends of the ribs of the frame have tissue penetrating elements about the periphery thereof which are configured to penetrate tissue lining the heart wall at an angle approximately perpendicular to a longitudinal axis of the partitioning device. The partitioning device has a hub with a non-traumatic distal end to engage the ventricular wall.

    摘要翻译： 本发明涉及一种用于将患者的心室分离成生产部分和非生产性部分的分隔装置。 该装置特别适用于治疗充血性心力衰竭患者。 分隔装置具有框架增强的可扩张膜，其分离心室的生产性和非生产性部分。 框架的肋的近端具有围绕其周边的组织穿透元件，其被构造成以大致垂直于分隔装置的纵向轴线的角度穿过围绕心脏壁的组织。 分隔装置具有带有非创伤性远端的毂以接合心室壁。

    Inflatable ventricular partitioning device
    35.
    发明申请
    Inflatable ventricular partitioning device 有权
    充气式心室分配装置

    公开(公告)号：US20050197716A1

    公开(公告)日：2005-09-08

    申请号：US10791916

    申请日：2004-03-03

    申请人： Hugh Sharkey ,  Alexander Khairkhahan

    发明人： Hugh Sharkey ,  Alexander Khairkhahan

    IPC分类号： A61F2/04

    CPC分类号： A61F2/2487

    摘要： This invention is directed to a device and method of using the device for partitioning a patient's heart chamber into a productive portion and a non-productive portion. The device is particularly suitable for treating patients with congestive heart failure. The device has an inflatable partitioning element which separates the productive and non-productive portions of the heart chamber and in some embodiments also has a supporting element, which may also be inflatable, extending between the inflatable partitioning element and the wall of the non-productive portion of the patient's heart chamber. The supporting element may have a non-traumatic distal end to engage the ventricular wall or a tissue penetrating anchoring element to secure the device to the patient's heart wall.

    摘要翻译： 本发明涉及一种使用该装置将患者的心室分成生产部分和非生产性部分的装置和方法。 该装置特别适用于治疗充血性心力衰竭患者。 该装置具有可分离心室的生产性和非生产性部分的可充气的分隔元件，并且在一些实施例中还具有支撑元件，该支撑元件也可以是可充气的，该可支撑元件在可膨胀的分隔元件和非生产性的壁之间延伸 患者心室的一部分。 支撑元件可以具有非创伤性远端以接合心室壁或组织穿透锚固元件以将装置固定到患者的心脏壁。

    Method and apparatus for stimulating nerve regeneration
    37.
    发明授权
    Method and apparatus for stimulating nerve regeneration 失效
    刺激神经再生的方法和装置

    公开(公告)号：US06436129B1

    公开(公告)日：2002-08-20

    申请号：US09488161

    申请日：2000-01-20

    申请人： Hugh Sharkey ,  Bruno Strul

    发明人： Hugh Sharkey ,  Bruno Strul

    IPC分类号： A61F700

    CPC分类号： A61B18/04 ,  A61B18/08 ,  A61B18/1477 ,  A61B2017/00026 ,  A61B2018/1425 ,  A61N7/00

    摘要： A method is provided for stimulating nerve growth, especially for nerve regeneration after damage to the nerve. The method comprises: applying thermal energy to one or more nerve segments adjacent a damaged region of the nerve, such that nerve fibers from the treated adjacent segment are stimulated to grow and extend toward the damaged region. The method may be used to enhance mechanical stimulative effect at a terminus of a severed nerve or a region of nerve injured by crush or other physical forces. The method may also be used to treat nerve segments retrograde up the nerve fiber and to increase the response of the injured nerve to regrowth and extension rapidly. An apparatus for delivery of thermal energy to the distal terminus of the severed nerve or region is disclosed. Thermal conductive or electromagnetic energy is delivered through a probe having a handle and a shaft. An energy delivery portion of the probe is configured to apply thermal energy to the distal segments of the severed nerve to promote rapid and more extensive growth of the nerve cells.

    摘要翻译： 提供一种刺激神经生长的方法，特别是对神经损伤后的神经再生。 该方法包括：将热能施加到邻近神经损伤区域的一个或多个神经节段，使得来自治疗的相邻区段的神经纤维被刺激生长并延伸到受损区域。 该方法可以用于增强在被切断的神经的末端或由挤压或其他物理力损伤的神经区域的机械刺激作用。 该方法还可用于治疗神经节段向上逆行神经纤维，并增加受损神经的再生长和迅速延伸的反应。 公开了一种用于将热能递送到切断的神经或区域的远端的装置。 导热或电磁能量通过具有手柄和轴的探针输送。 探针的能量输送部分构造成将热能施加到切断的神经的远端段，以促进神经细胞的快速和更广泛的生长。