摘要:
An improved splittable medical device introducer designed to introduce a medical device such as a lead or catheter, into a patient's vasculature without loss of blood or introduction of air is described. The introducer assembly is designed with a notch provided at the proximal end of the introducer housing. The notch, which may comprise a multitude of cross-sectional geometries, is designed to reduce the force required to separate the housing and the introducer sheath, thereby minimizing the possibility of unintentional dislodgement during separation. The notch also increases the repeatability and consistency of the amount of force required to separate the introducer housing and sheath.
摘要:
Computer-implemented methods, systems, and computer program products for document authentication and identification using encoding and decoding are provided. A method includes receiving a digitized document and comparing the digitized document to a set of markers to determine whether the digitized document is an encoded document with one or more characters replaced. In response to determining that the digitized document is encoded, information is extracted from the set of markers using a decoder according to an encoding strategy. The extracted information and the set of markers are compared with data stored in encoding history to authenticate and identify the received digitized document. Markers in the encoded document may be hidden in plain sight, such that the encoding is not readily apparent to a casual observer.
摘要:
A deflectable sheath for use in medical procedures in the vasculature is described. The sheath includes a handle supporting the sheath. Two pull wires run along opposite sides of the sheath to anchors at the deflectable distal end. The handle includes a rotatable member that moves a threaded member including wire guide in a back and forth translation. As the movement occurs, force is applied to either one or the other of the pull wires to cause deflection of distal end of the sheath in either and upwardly or a downwardly direction with respect to the longitudinal axis of the sheath.
摘要:
The invention provides nucleic acids, and variants and fragments thereof, obtained from strains of Bacillus thuringiensis encoding polypeptides having pesticidal activity against insect pests, including Lepidoptera. Particular embodiments of the invention provide isolated nucleic acids encoding pesticidal proteins, pesticidal compositions, DNA constructs, and transformed microorganisms and plants comprising a nucleic acid of the embodiments. These compositions find use in methods for controlling pests, especially plant pests.
摘要:
Information in a diagram is logically structured using lists, containers, and callouts without requiring the diagram author to explicitly define a structure or map any diagram contents to a structure. Logical relationships are inferred based on actions associated with shapes, groupings, and attributes of shapes/groupings taken by the author. Feedback mechanisms are provided to communicate an underlying structure to the author. Intelligent behaviors are enabled to expose manipulation of diagrams based on their logical structure.
摘要:
Methods and compositions are provided which employ a silencing element that, when ingested by a pest, such as a pest from the Lepidoptera order, they are capable of decreasing the expression of a target sequence in the pest. In specific embodiments, the decrease in expression of the target sequence controls the pest and thereby the methods and compositions are capable of limiting damage to a plant. The present invention provides target polynucleotides encoding polypeptides from specific protein families and various target polynucleotides set forth in SEQ ID NOS: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, or 50 or active variants and fragments thereof, wherein a decrease in expression of one or more the sequences in the target pest controls the pest (i.e., has insecticidal activity). Further provided are silencing elements which when ingested by the pest decrease the level of the target polypeptide and thereby control the pest. In specific embodiment, the pest is Spodoptera frugiperda. Plants, plant part, bacteria and other host cells comprising the silencing elements or an active variant or fragment thereof of the invention are also provided.
摘要:
A system for selectively controlling electrical outlets using power profiling is disclosed. There is a plurality of electrical outlets that each comprises a power socket capable of receiving a plug, an outlet identification and a switch that when in a first position no power is available at the power socket, and when the switch is in a second position power is available at the power socket. A controller is in electronic communication with the plurality of electrical outlets. The controller includes a processor and memory in electronic communication with the processor. The controller also includes power profiles and operates to receive data from an electrical outlet of the plurality of electrical outlets. A device or class of device is identified based on the received data. A power profile is identified based on the received data. Action is taken based on the power profile.
摘要:
13-substituted methacycline compounds, methods of treating tetracycline responsive states, and pharmaceutical compositions containing the 13-substituted methacycline compounds are described.
摘要:
A system and a method for automatically, accurately diluting chemical solutions on an industrial scale based upon real time weight measurements of chemical and diluent weight is disclosed.
摘要:
The present invention pertains, at least in part, to novel substituted 4-dedimethylamino tetracycline compounds. These tetracycline compounds can be used to treat numerous tetracycline compound-responsive states, such as bacterial infections and neoplasms, as well as other known applications for minocycline and tetracycline compounds in general, such as blocking tetracycline efflux and modulation of gene expression.