公开(公告)号：US08338686B2

公开(公告)日：2012-12-25

申请号：US12791798

申请日：2010-06-01

申请人： David Mann ,  Francesco Gerald Capodieci ,  Reza Rassool

发明人： David Mann ,  Francesco Gerald Capodieci ,  Reza Rassool

IPC分类号： A63H5/00 ,  G04B13/00

CPC分类号： G10H7/00 ,  G06F3/0481 ,  G06F3/167 ,  G09B15/00 ,  G10H1/0025 ,  G10H1/38 ,  G10H2210/125 ,  G10H2220/101 ,  G10H2220/111 ,  G10H2230/015 ,  G10H2240/075

摘要： An apparatus for enhancing audio comprising a first interface and a harmonizing module is disclosed. The first interface receive a first audio segment from a first source. The harmonizing module is coupled to the first interface. The harmonizing module is configured to identify at least one musical property of the first audio segment; calculate a subset of notes that are harmonious with the first audio segment based on the at least one musical property; and select from the subset of notes to generate an audio track to be played substantially synchronously with the first audio segment. A second interface may also be provided to receive a second audio segment from a second source. In this case, the harmonizing module may be configured to generate the audio track by transforming one or more notes of the second audio segment. A method is also provided.

摘要翻译： 公开了一种用于增强音频的装置，包括第一接口和协调模块。 第一个接口从第一个源接收第一个音频段。 协调模块耦合到第一接口。 协调模块被配置为识别第一音频段的至少一个音乐属性; 基于所述至少一个音乐属性计算与所述第一音频段和谐的音符的子集; 并且从音符子集中选择以产生要与第一音频段基本同步地播放的音轨。 还可以提供第二接口以从第二源接收第二音频段。 在这种情况下，协调模块可以被配置为通过变换第二音频段的一个或多个音符来生成音轨。 还提供了一种方法。

公开(公告)号：US20100098904A1

公开(公告)日：2010-04-22

申请号：US11588873

申请日：2006-10-26

申请人： Hongjie Dai ,  David Mann ,  Guangyu Zhang

发明人： Hongjie Dai ,  David Mann ,  Guangyu Zhang

IPC分类号： B32B7/00 ,  C23C16/44 ,  B32B38/10 ,  B32B9/00

CPC分类号： B82Y40/00 ,  B82Y30/00 ,  C01B32/162 ,  C01B2202/02 ,  Y10T428/24 ,  Y10T428/24174 ,  Y10T428/30

摘要： The present invention provides single-walled carbon nanotubes and systems and methods for their preparation.

摘要翻译： 本发明提供单壁碳纳米管及其制备方法和制备方法。

公开(公告)号：US20090068387A1

公开(公告)日：2009-03-12

申请号：US11881746

申请日：2007-07-26

申请人： Matthew Panzer ,  Kenneth E. Goodson ,  Xuejiao Hu ,  David Mann

发明人： Matthew Panzer ,  Kenneth E. Goodson ,  Xuejiao Hu ,  David Mann

IPC分类号： B32B7/00 ,  B32B37/00

CPC分类号： B32B37/02 ,  B32B2038/0092 ,  B32B2309/02 ,  B32B2309/105 ,  B32B2311/00 ,  B32B2313/04 ,  B82Y10/00 ,  B82Y30/00 ,  H01L23/373 ,  H01L2924/0002 ,  Y10T428/14 ,  Y10T428/24124 ,  Y10T428/24132 ,  Y10T428/24174 ,  Y10T428/249927 ,  Y10T428/30 ,  H01L2924/00

摘要： A thermal interface material includes a mechanically compliant vertically aligned nanofiber film and a binder material for joining the nanofibers of the film to the surfaces of two substrates. Preferably, the binder material comprises a non-hydrocarbon-based material such as a metallic eutectic with a melting temperature below a nanofiber thermal damage threshold temperature of the film. The film is grown on a substrate which is then bonded to another substrate by the binder material in an adhesion process that may include pressure and heat. Alternatively, the film may be released from the substrate to produce a stand-alone thermal tape which may later be placed between two substrates and bonded.

摘要翻译： 热界面材料包括机械顺应的垂直排列的纳米纤维膜和用于将膜的纳米纤维连接到两个基底的表面的粘合剂材料。 优选地，粘合剂材料包括非烃基材料，例如熔融温度低于膜的纳米纤维热损伤阈值温度的金属共晶。 该膜在基材上生长，然后通过粘合剂材料在可能包括压力和热量的粘附过程中将其粘合到另一个基材上。 或者，膜可以从基底释放以产生可以稍后放置在两个基底之间并结合的独立的热带。

公开(公告)号：US20060025460A1

公开(公告)日：2006-02-02

申请号：US11156364

申请日：2005-06-17

申请人： Alfredo Castro ,  Wei Deng ,  Kristopher Depew ,  Michael Foley ,  Christian Fritz ,  Asimina Georges Evangelinos ,  Michael Grogan ,  Nafeeza Hafeez ,  Edward Holson ,  Brian Hopkins ,  Nii Koney ,  Tao Liu ,  David Mann ,  Lisa Marcaurelle ,  Daniel Snyder ,  Dennis Underwood ,  Andrew Wylie ,  Lin-Chen Yu ,  Linping Zhang

发明人： Alfredo Castro ,  Wei Deng ,  Kristopher Depew ,  Michael Foley ,  Christian Fritz ,  Asimina Georges Evangelinos ,  Michael Grogan ,  Nafeeza Hafeez ,  Edward Holson ,  Brian Hopkins ,  Nii Koney ,  Tao Liu ,  David Mann ,  Lisa Marcaurelle ,  Daniel Snyder ,  Dennis Underwood ,  Andrew Wylie ,  Lin-Chen Yu ,  Linping Zhang

IPC分类号： C07D261/02 ,  A61K31/42

CPC分类号： C07D261/02 ,  C07D261/18 ,  C07D413/10 ,  C07D413/12 ,  C07D417/12 ,  C07D498/04

摘要： One aspect of the present invention relates to heterocyclic compounds that bind to bcl proteins and inhibit Bcl function. Another aspect of the present invention relates to compositions comprising a heterocyclic compound of the invention. The present invention provides methods for treating and modulating disorders associated with hyperproliferation, such as cancer.

公开(公告)号：US20050271463A1

公开(公告)日：2005-12-08

申请号：US10861436

申请日：2004-06-03

申请人： David Mann

发明人： David Mann

IPC分类号： B25G1/04 ,  B25G1/08 ,  F16B7/10 ,  F16B37/08

CPC分类号： B25G1/08 ,  F16B37/0842 ,  Y10T16/444 ,  Y10T16/4719 ,  Y10T403/32467 ,  Y10T403/7077

摘要： A grip for an extension pole has an opening at one end sized to receive the inboard end of the extension pole, and another opening at the other end communicating with a storage compartment inside the grip for storing at least a portion of an adaptor. A gripper inside the grip engages the adaptor when inserted into the storage compartment to prevent the adaptor from inadvertently falling out of the storage compartment.

摘要翻译： 用于延伸杆的把手的一端具有开口，其尺寸设置成接收延伸杆的内侧端部，另一端的另一端与位于把手内的储存室连通，用于存储适配器的至少一部分。 当插入存储隔间时，把手内的把手与适配器接合，以防止适配器无意中从存储隔间掉出。

公开(公告)号：USD366765S

公开(公告)日：1996-02-06

申请号：US032423

申请日：1994-12-19

申请人： David Mann

设计人： David Mann

公开(公告)号：US5406959A

公开(公告)日：1995-04-18

申请号：US173571

申请日：1993-12-22

申请人： David Mann

发明人： David Mann

IPC分类号： A61B10/02 ,  A61B10/00 ,  A61B10/04 ,  A61M25/00

CPC分类号： A61B10/04 ,  A61M25/0041

摘要： A method and apparatus for obtaining a biopsy from an artery includes the steps of: inserting a catheter into an artery, positioning the catheter at a desired location within the artery, cutting a biopsy sample from the inner surface of the artery, and withdrawing the catheter and biopsy sample from the artery with the biopsy sample protected and its orientation with respect to its parent tissue preserved. The catheter includes an inner tube coupled to a vacuum source and having a beveled opening for contacting the artery. An outer tube is slidably mounted to the inner tube and has a cutting edge which slides over and severs arterial tissue retained in the beveled opening.

摘要翻译： 用于从动脉获得活组织检查的方法和装置包括以下步骤：将导管插入动脉，将导管定位在动脉内的期望位置，从动脉内表面切割活组织检查样品，并取出导管 来自动脉的活组织检查样品保护活检样品，并保护其相对于其母体组织的取向。 导管包括联接到真空源并具有用于接触动脉的斜切开口的内管。 外管可滑动地安装到内管上，并具有切割边缘，该切割边缘在保持在斜切开口中的动脉组织上滑动并切断。

公开(公告)号：US5287857A

公开(公告)日：1994-02-22

申请号：US901830

申请日：1992-06-22

申请人： David Mann

发明人： David Mann

IPC分类号： A61B10/02 ,  A61B10/00 ,  A61B10/04 ,  A61M25/00

CPC分类号： A61B10/04 ,  A61M25/0041

摘要： An arterial biopsy catheter for obtaining a biopsy sample from the inner layers of an artery includes an outer tube and an inner tube slidingly mounted within the outer tube. The inner tube is formed with a closed distal end having a beveled opening. The outer tube is formed with an open distal end having a sharpened circumferential edge adapted to cut arterial material in contact with the beveled opening by sliding the outer tube over the inner tube. The inner tube and outer tube are attached to handles for manipulation by an operator. In use, a vacuum is applied through the inside diameter of the inner tube to the beveled opening, to draw arterial material into contact with the beveled opening. The outer tube is then manipulated to sever the arterial material to form the biopsy sample. The inner and outer tubes are then withdrawn from the artery with the biopsy material held in the beveled opening.

摘要翻译： 用于从动脉内层获得活检样本的动脉活检导管包括外管和滑动地安装在外管内的内管。 内管形成有具有斜切开口的封闭远端。 外管形成具有开口的远端，其具有锋利的圆周边缘，其适于通过将外管滑过内管而切割与斜切开口接触的动脉材料。 内管和外管连接到手柄以由操作者操纵。 在使用中，将真空通过内管的内径施加到斜切开口，以使动脉材料与斜切开口接触。 然后操作外管以切断动脉材料以形成活组织检查样品。 然后将内管和外管从动脉中取出，活检材料保持在斜切开口中。