利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

918 条记录 (耗时 0.028 秒)

    Stereospecific synthesis process for tretinoin compounds
    31.
    发明授权
    Stereospecific synthesis process for tretinoin compounds 有权
    维A酸化合物的立体定向合成方法

    公开(公告)号：US08835680B1

    公开(公告)日：2014-09-16

    申请号：US14117343

    申请日：2012-05-07

    申请人： Qingjun Deng ,  Shaohui Wang ,  Qiang Zhu ,  Taiping Gao ,  Yongsheng Li

    发明人： Qingjun Deng ,  Shaohui Wang ,  Qiang Zhu ,  Taiping Gao ,  Yongsheng Li

    IPC分类号： C07C61/16 ,  C07C53/134 ,  C07C51/00

    CPC分类号： C07C51/00 ,  C07C51/353 ,  C07C403/20 ,  C07C2601/16 ,  C07C59/64

    摘要： A stereospecific synthesis process for tretinoin compounds comprises the following steps: using substituted triphenyl phosphine salt and β-formyl crotonic acid as raw material to carry out WITTIG reaction under the action of alkali; then adjusting the pH of the reaction liquid to 5-10; adding palladium compound or rhodium compound to carry out isomerization directly and obtain tretinoin compounds with desired configuration. The product yield of the process is high and the intermediate product in the reaction dose not need to be separated. The process is easy to operate and can save the production cost and as well is suitable for industrial production.

    摘要翻译： 维A酸化合物的立体特异性合成方法包括以下步骤：使用取代的三苯基膦盐和巴豆酮基巴豆酸作为原料，在碱的作用下进行WITTIG反应; 然后将反应液的pH调节至5-10; 加入钯化合物或铑化合物直接进行异构化，得到具有所需结构的维甲酸化合物。 该方法的产物产率高，反应中的中间产物不需要分离。 该工艺易于操作，可节省生产成本，适用于工业生产。

    Processes for the production of acrylic acids and acrylates
    33.
    发明授权
    Processes for the production of acrylic acids and acrylates 有权
    用于生产丙烯酸和丙烯酸酯的方法

    公开(公告)号：US08729299B2

    公开(公告)日：2014-05-20

    申请号：US13428065

    申请日：2012-03-23

    申请人： Sean Mueller ,  Josefina Chapman ,  Craig Peterson ,  Dick Nagaki

    发明人： Sean Mueller ,  Josefina Chapman ,  Craig Peterson ,  Dick Nagaki

    IPC分类号： C07C57/02

    CPC分类号： C07C51/353 ,  Y02P20/582 ,  C07C57/04

    摘要： In one embodiment, the invention is to a process for producing an acrylate product. The process comprises the step of reacting a reaction mixture comprising an alkanoic acid, an alkylenating agent, and oxygen over a catalyst and under conditions effective to form a crude acrylate product. Preferably, the reaction mixture comprises from 0.5 wt % to 10 wt % oxygen. The crude acrylate product comprises acrylate product and alkylenating agent. The process further comprises the step of separating at least a portion of the crude product to form at least one alkylenating agent stream and at least one purified acrylate product stream. The purified acrylate product stream comprises acrylate product.

    摘要翻译： 在一个实施方案中，本发明涉及一种生产丙烯酸酯产物的方法。 该方法包括通过催化剂和有效形成粗制丙烯酸酯产物的条件使包含链烷酸，亚烷基化试剂和氧的反应混合物反应的步骤。 优选地，反应混合物包含0.5重量％至10重量％的氧气。 丙烯酸粗产物包含丙烯酸酯产物和亚烷基化剂。 该方法还包括分离至少一部分粗产物以形成至少一种亚烷基化剂流和至少一种纯化的丙烯酸酯产物流的步骤。 纯化的丙烯酸酯产物流包含丙烯酸酯产物。

    Process for Making Acrylic Acid by Integrating Acetic Acid Feed Stream from Carbonylation Process
    35.
    发明申请
    Process for Making Acrylic Acid by Integrating Acetic Acid Feed Stream from Carbonylation Process 审中-公开
    通过从乙酰化过程中整合乙酸进料流制备丙烯酸的方法

    公开(公告)号：US20140073812A1

    公开(公告)日：2014-03-13

    申请号：US14018571

    申请日：2013-09-05

    申请人： Celanese International Corporation

    发明人： Tianshu Pan ,  Mark O. Scates ,  Ronald D. Shaver ,  G. Paull Torrence ,  Josefina T. Chapman ,  Sean Mueller

    IPC分类号： C07C51/12

    CPC分类号： C07C51/12 ,  C07C51/353 ,  C07C53/08 ,  C07C57/04

    摘要： In one embodiment, the invention is to a process for producing acrylic acid, comprising the step of providing from a distillation column in a carbonylation process a purified acetic acid stream comprising at least 0.15 wt % water. The process further comprises the step of condensation acetic acid of the purified acetic acid stream and an alkylenating agent in the presence of a catalyst and under conditions effective to form a crude acrylate product comprising acrylic acid and water. Acrylic acid is recovered from the crude acrylate product.

    摘要翻译： 在一个实施方案中，本发明涉及一种制备丙烯酸的方法，其包括在羰基化方法中从蒸馏塔提供包含至少0.15重量％水的纯化乙酸流的步骤。 该方法还包括在催化剂存在下和有效形成包含丙烯酸和水的粗丙烯酸酯产物的条件下，将纯化的乙酸流冷凝乙酸和亚烷基化剂的步骤。 从粗丙烯酸酯产物回收丙烯酸。

    Method for Producing Unsaturated Compounds
    36.
    发明申请
    Method for Producing Unsaturated Compounds 有权
    生产不饱和化合物的方法

    公开(公告)号：US20140046081A1

    公开(公告)日：2014-02-13

    申请号：US14112454

    申请日：2012-02-25

    申请人： Lukas J. Goossen ,  Dominik Ohlmann ,  Markus Dierker

    发明人： Lukas J. Goossen ,  Dominik Ohlmann ,  Markus Dierker

    IPC分类号： C07C51/353 ,  C07C67/333

    CPC分类号： C07C51/353 ,  B01J31/2217 ,  B01J31/2273 ,  B01J31/2278 ,  B01J31/24 ,  B01J2231/52 ,  B01J2231/543 ,  B01J2531/0216 ,  B01J2531/821 ,  B01J2531/824 ,  C07C67/333 ,  C07C67/475 ,  C07C2531/24 ,  C10G2300/1011 ,  C10L1/026 ,  C11C3/00 ,  Y02P30/20 ,  C07C69/533 ,  C07C69/593 ,  C07C57/03 ,  C07C57/13

    摘要： The invention relates to a method for producing compositions containing unsaturated compounds, wherein (A) one or more unsaturated monocarboxylic acids having 10 to 24 C-atoms or esters of said monocarboxylic acids and optionally (B) one or more compounds having at least one C═C double bond (wherein the compounds (B) are different from the compounds (A)) are subjected to a tandem isomerization/metathesis reaction sequence in the presence of a palladium catalyst and a ruthenium catalyst, providing that the palladium catalysts used are compounds that contain at least one structural element Pd—P(R1R2R3), wherein the radicals R1 to R3, independently of one another, each comprise 2 to 10 C-atoms, which may be aliphatic, alicyclic, aromatic or heterocyclic respectively, providing that at least one of the radicals R1 to R3 contains a beta-hydrogen, wherein the palladium catalyst is used as such or is produced in situ, providing that the method is carried out in the absence of substances that have a pKa value of 3 or less.

    摘要翻译： 本发明涉及一种生产含有不饱和化合物的组合物的方法，其中（A）一种或多种具有10-24个C原子的不饱和一元羧酸或所述一元羧酸的酯和任选的（B）一种或多种具有至少一个C = C双键（其中化合物（B）不同于化合物（A））在钯催化剂和钌催化剂存在下进行串联异构化/复分解反应，条件是所用的钯催化剂是化合物 其包含至少一个结构单元Pd-P（R 1 R 2 R 3），其中基团R 1至R 3彼此独立地各自包含2至10个C原子，其可以分别为脂族，脂环族，芳族或杂环，条件是在 基团R1至R3中的至少一个含有β-氢，其中钯催化剂原样使用或原位生产，条件是该方法在不存在物质的情况下进行 pKa值为3以下。

    Process for Preparing Saturated Branched Chain Fatty Acids
    39.
    发明申请
    Process for Preparing Saturated Branched Chain Fatty Acids 有权
    制备饱和支链链脂肪酸的方法

    公开(公告)号：US20130310587A1

    公开(公告)日：2013-11-21

    申请号：US13950798

    申请日：2013-07-25

    申请人： The United States of America, as represented by the Secretary of Agriculture

    发明人： Helen Ngo ,  Thomas A. Foglia

    IPC分类号： C07C67/333

    CPC分类号： C07C67/333 ,  B01J29/90 ,  C07C51/353 ,  C07C51/36 ,  Y02P20/584 ,  C07C57/03 ,  C07C53/126

    摘要： A process for preparing saturated branched chain fatty acids or alkyl esters thereof involving subjecting unsaturated fatty acids having 10 to 25 carbon atoms, alkyl esters thereof or mixtures thereof to a skeletal isomerization reaction in the presence of water or a lower alcohol at a temperature of about 240° C. to about 280° C. using a combination of a sterically hindered Lewis base and zeolite as a Brönsted or Lewis acid catalyst, and isolating saturated branched chain fatty acids or alkyl esters thereof or mixtures thereof from the reaction mixture obtained by the skeletal isomerization reaction; wherein the process further comprises (a) recycling said catalyst by washing said catalyst with an acid solution at about 55° C. for about 24 hours, recovering the catalyst followed by heating the catalyst at about 115° C. for about 20 hours for the first four or five cycles of use and (b) in the next subsequent cycle recycling the catalyst by heating the catalyst at about 115° C. for about 20 hours followed by adding Lewis base to the catalyst; steps (a) and (b) can be repeated in subsequent cycles. The yield of said saturated branched chain fatty acids is ≧70 wt %. The sterically hindered Lewis base is a tertiary amine or phosphine with linear or branched C1 to C6 alkyl or phenyl groups attached thereto.

    摘要翻译： 一种制备饱和支链脂肪酸或其烷基酯的方法，其包括使具有10-25个碳原子的不饱和脂肪酸，其烷基酯或其混合物在水或低级醇的存在下在约 240℃至约280℃，使用空间位阻路易斯碱和沸石作为布朗斯特或路易斯酸催化剂的组合，并将饱和支链脂肪酸或其烷基酯或其混合物从由 骨架异构化反应; 其中所述方法还包括（a）通过在约55℃下用酸溶液洗涤所述催化剂约24小时来回收所述催化剂，回收催化剂，然后在约115℃下加热催化剂约20小时，以使 前四个或五个循环使用，（b）在下一个随后的循环中，通过在约115℃下加热催化剂约20小时，再循环催化剂，然后向催化剂中加入路易斯碱; 步骤（a）和（b）可以在随后的循环中重复。 所述饱和支链脂肪酸的产率> 70重量％。 空间位阻路易斯碱是具有直链或支链C1至C6烷基或苯基的叔胺或膦。