Process for the production of citric acid by submerged fermentation
    31.
    发明授权
    Process for the production of citric acid by submerged fermentation 失效
    通过发酵发酵生产柠檬酸的方法

    公开(公告)号:US3741869A

    公开(公告)日:1973-06-26

    申请号:US3741869D

    申请日:1971-05-24

    发明人: KABIL A

    IPC分类号: C12P7/48 C12D1/04

    CPC分类号: C12P7/48 Y10S435/917

    摘要: THE INVENTION RELATES TO A PROCESS FOR THE PRODUCTION OF CITRIC ACID WITH COMPRISES SUBJECTING A PARTIALLY DECATIONIZED CARBOHYDRATE-CONTAINING SOLUTION TO A SUBMERGED FERMENTATION WITH A CITRIC ACID PRODUCTION STRAIN OF ASPERGILLUS NIGER IN THE PRESENCE OF K4(FE(CN)6).3H2O AS AN INHIBITOR IN AN AMOUNT OF LESS THAN 500 P.P.M.

    Method for the production of glucose oxidase
    32.
    发明授权
    Method for the production of glucose oxidase 失效
    葡萄糖氧化酶的生产方法

    公开(公告)号:US3701715A

    公开(公告)日:1972-10-31

    申请号:US3701715D

    申请日:1971-02-04

    申请人: DAWE S LAB INC

    IPC分类号: C12N9/04 C12D13/10

    摘要: THIS INVENTION IS ADDRESSED TO AN IMPROVED METHOD FOR THE PREPARATION OF GLUCOSE OXIDASE IN WHICH GLUCOSE OXIDASE-PRODUCING STRAINS OF THE GENERA ASPERGILLUS AND PENICILLIUM ARE CULTIVATED IN MEDIUM HAVING A LOW CARBOHYDRATE CONTENT IN WHICH THE CARBOHYDRATE HAS A DEXTROSE EQUIVALENT OF 60-85, IN THE PRESENCE OF HYDRATED MAGNESIUM SULFATE, MONOPOTASSIUM PHOSPHATE, AND A SOURCE OF ASSIMILABLE NITROGEN IN THE FORM OF A NITRATE SALT OR AN AMMONIUM SALT.

    Microbiological hydroxylation of 6-substituted-2-isopropyl naphthalenes
    33.
    发明授权
    Microbiological hydroxylation of 6-substituted-2-isopropyl naphthalenes 失效
    6-取代-2-异丙基萘磺酸的微生物羟化

    公开(公告)号:US3687813A

    公开(公告)日:1972-08-29

    申请号:US3687813D

    申请日:1970-05-14

    申请人: SYNTEX CORP

    发明人: WANG KUANG-CHAO

    IPC分类号: C12P7/22 C12P11/00 C12D1/00

    摘要: MICROBIOLOGIC AL PROCESSES FOR HYDROXYLATING 6-SUBSTITUTED -2- ISOPROPYL-NAPHTHALENE COMPOUNDS TO THE CORRESPONDING 6-SUBSTITUTED-NAPHTHALENE PROPANOLS (E.G. 2-(6''METHOXY -2''-NAPHTYL)-1-PROPANOL; AND 2-(6''-THIOMETHYL2''-NAPHTHYL)-1-PROPANOL). THE PROCESSES ARE CHARACTERIZED BY TREATING THE 6-SUBSTITUTED-2-ISOPROPYL-NAPHTAHALENE COMPOUND WITH THE SPECIES OF THE GENUS OF FUNGI ASPERGILLUS, IDENTIFIED AS ASPERGILLUS NIGER, IN THE PRESENCE OF A NUTRIENT MEDIUM UNDER CONDITIONS CONDUCIVE TO THE MICROBIOLOGICAL AGENT. THE RESULTING PROPANOL COMPOUNDS EXHIBIT ANALGESIC, ANTI-INFLAMMATORY, AND ANTI-PYRETIC ACTIVITIES IN MAMMALS AND ACCORDINGLY HAVE UTILITY WHERE SUCH AGENTS ARE INDICATED. THE PROPANOL COMPOUNDS CAN ALSO BE CONVERTED INTO THE CORRESPONDING PROPIONIC ACID COMPOUNDS WHICH ALSO HAVE UTILITY AS ANTI-UNFLAMMATORY, ANALGESIC AND ANTI-PYRETIC AGENTS IN TREATMENT OF MAMMALS.