公开(公告)号：US09404799B2

公开(公告)日：2016-08-02

申请号：US14213214

申请日：2014-03-14

Applicant: WESTCO SCIENTIFIC INSTRUMENTS, INC.

Inventor： Jerome J. Workman, Jr. ,  Tushar Saraf ,  Thomas Andrew Bennett

IPC: G01J3/18 ,  G01J3/02 ,  G01J3/06 ,  G01J3/10

CPC classification number: G01J3/027 ,  G01J3/0202 ,  G01J3/06 ,  G01J3/10 ,  G01J3/18 ,  G01J2003/1866

Abstract: Aspects of a tandem dispersive range monochromator are described herein. In one embodiment, the monochromator includes a light source that provides broadband light, a tandem diffraction grating including a first diffraction grating and a second diffraction grating, a grating drive motor that rotates the tandem diffraction grating to provide dispersed wavelengths of light, a detector that detects a portion of the dispersed wavelengths of light, and processing circuitry that controls a grating drive motor to regulate an angular velocity of the tandem grating based on an angular orientation of the tandem diffraction grating. By using a tandem diffraction grating having different dispersive surfaces, measurements of relatively high precision and quality may be taken throughout a wider spectral range. In another aspect, the processing circuitry controls a sample drive motor to vary an angle of incidence of the dispersed wavelengths of light onto a sample for evaluation.

Abstract translation: 这里描述了串联色散范围单色仪的方面。 在一个实施例中，单色器包括提供宽带光的光源，包括第一衍射光栅和第二衍射光栅的串联衍射光栅，旋转串联衍射光栅以提供分散的波长的光栅的光栅驱动马达，检测器 检测部分分散的光的波长，以及处理电路，其控制光栅驱动电机，以基于串联衍射光栅的角取向来调节串联光栅的角速度。 通过使用具有不同色散表面的串联衍射光栅，可以在更宽的光谱范围内进行相对高精度和质量的测量。 在另一方面，处理电路控制样品驱动电机以将分散的波长波长的入射角度改变到样品上用于评估。

公开(公告)号：US09366694B2

公开(公告)日：2016-06-14

申请号：US14761726

申请日：2014-01-13

Applicant: Ecole Polytechnique ,  Centre National de la Recherche Scientifique

Inventor： Marc Chaigneau ,  Akli Karar ,  Bernard Drevillon ,  Razvigor Ossikovski

IPC: G01J3/44 ,  G01Q10/00 ,  G01Q10/04 ,  G01Q20/04 ,  G01Q30/02 ,  G01Q60/04 ,  G01Q60/16 ,  G01Q60/26 ,  G01N21/65 ,  G01J3/06 ,  G01Q40/00

CPC classification number: G01Q10/00 ,  G01J3/06 ,  G01J3/44 ,  G01N21/658 ,  G01Q10/045 ,  G01Q20/04 ,  G01Q30/02 ,  G01Q40/00 ,  G01Q60/04 ,  G01Q60/16 ,  G01Q60/26

Abstract: A multimode local probe microscope having a resonator, a first electrode, and a second electrode, an excitation source adapted to generate mechanical resonance in the resonator, a metal tip fastened to the resonator, movement mechanism for imparting relative movement between the local probe and a sample and adapted to bring the end of the tip to within a distance Z lying in the range 0 to 100 nm, and detector for detecting at least one electrical signal representative of friction forces at the terminals of said electrodes. The metal tip is electrically connected to the output second electrode and the microscopy apparatus includes amplifier and filter for amplifying and filtering signals relating to the friction forces and to the tunnelling current in a single electronic circuit, and configured for regulating the distance Z between the end of the tip and the surface of the sample.

Abstract translation: 一种具有谐振器，第一电极和第二电极的多模式局部探针显微镜，适于在谐振器中产生机械共振的激发源，固定到谐振器的金属尖端，用于在局部探针和 采样并适于使尖端的端部处于位于0至100nm范围内的距离Z内;以及检测器，用于检测表示在所述电极的端子处的摩擦力的至少一个电信号。 金属尖端电连接到输出第二电极，显微镜装置包括放大器和滤波器，用于放大和滤除与单个电子电路中的摩擦力和隧道电流相关的信号，并且被配置用于调节端部之间的距离Z 的尖端和样品的表面。

公开(公告)号：US20160123812A1

公开(公告)日：2016-05-05

申请号：US14891475

申请日：2014-05-21

Applicant: CANON KABUSHIKI KAISHA

Inventor： Masafumi Kyogaku

IPC: G01J3/44 ,  G01J3/06 ,  G02B21/00

CPC classification number: G01J3/4412 ,  G01J3/06 ,  G01N21/3151 ,  G01N21/65 ,  G01N2021/653 ,  G02B21/002

Abstract: A spectral microscopy device includes a spectral detecting unit including a light source capable of controlling an output wavelength, a microscope section having an observation area illuminated with light output from the light source, and a signal detector that detects light from the observation area as spectral data; a moving unit configured to move the observation area; and a controller that performs a control operation to allow the spectral detecting unit and the moving unit to move in response to each other. The spectral microscopy device is controlled so that switching between different measurement conditions based on the number of measurement points is performed at an observation area movement time in which the observation area is moved by the moving unit and measurement is performed and at a an observation area movement stoppage time in which the observation area is fixed and measurement is performed, and spectral data is detected.

Abstract translation: 光谱显微镜装置包括：光谱检测单元，包括能够控制输出波长的光源;具有由光源输出的光照射的观察区域的显微镜部分;以及检测来自观察区域的光作为光谱数据的信号检测器 ; 移动单元，被配置为移动所述观察区域; 以及控制器，其执行控制操作以允许所述光谱检测单元和所述移动单元彼此响应地移动。 控制光谱显微镜装置，使得在观察区域移动时间中，通过移动单元移动观察区域并进行测量，并且在观察区域移动中执行基于测量点数的不同测量条件之间的切换 观察区域固定并进行测量的停止时间，并检测光谱数据。

公开(公告)号：US09295420B2

公开(公告)日：2016-03-29

申请号：US14327553

申请日：2014-07-09

Applicant: Hong Kong Applied Science and Technology Research Institute Co. Ltd.

Inventor： Chun Zhang ,  Ka Cheung Kwok ,  Lydia Lap Wai Leung

IPC: G01J3/44 ,  A61B5/1455 ,  G01N21/63 ,  A61B5/00 ,  G01N21/65 ,  G01J3/02

CPC classification number: A61B5/1455 ,  A61B5/0075 ,  G01J3/0202 ,  G01J3/0216 ,  G01J3/0227 ,  G01J3/0237 ,  G01J3/06 ,  G01J3/44 ,  G01N21/63 ,  G01N21/65 ,  G01N2201/06113

Abstract: A transmission-reflectance swappable Raman device and a method thereof are disclosed. The excitation light is selectively directed to the sample in one direction for generating the transmission Raman signal in transmission mode or in another direction for generating the reflectance Raman signal in reflectance mode. The content of an analyte in a sample can be determined by analyzing transmission and reflectance Raman signal.

Abstract translation: 公开了一种透射反射可交换拉曼装置及其方法。 激发光在一个方向上选择性地导向样品，以在透射模式或另一方向上产生透射拉曼信号，以在反射模式下产生反射拉曼信号。 可以通过分析透射和反射拉曼信号来确定样品中分析物的含量。

公开(公告)号：US20160018261A1

公开(公告)日：2016-01-21

申请号：US14732170

申请日：2015-06-05

Applicant: TECAN Trading AG

Inventor： Lutz NIGGL ,  Andreas STEINBACHER

IPC: G01J3/18 ,  G01N21/64 ,  G01N21/25 ,  G01J3/06

CPC classification number: G01J3/18 ,  G01J3/06 ,  G01J2003/062 ,  G01N21/255 ,  G01N21/64 ,  G01N2201/0635

Abstract: A monochromator has at least one optical grating which is rotatable in relation to incident light of a source of light, a drive unit to rotate the optical grating by a connected drive rod around a longitudinal axis, and a control unit to control the drive unit and thereby the rotation of the optical grating. The drive unit further has a first damping element with at least one electrical conductive surface, and a second damping element which provides at least one magnetic field having a magnetic axis which penetrates the electrical conductive surface. One of the first and second damping elements is fixed to the drive rod and is rotatable along with the drive rod around the longitudinal axis thereof in relation to the other one of the second or first damping element.

Abstract translation: 单色仪具有至少一个相对于光源的入射光可旋转的光栅;驱动单元，用于通过连接的驱动杆围绕纵轴旋转光栅;以及控制单元，用于控制驱动单元和 从而光栅的旋转。 驱动单元还具有带有至少一个导电表面的第一阻尼元件和提供至少一个具有穿过导电表面的磁轴的磁场的第二阻尼元件。 第一和第二阻尼元件中的一个被固定到驱动杆，并且可以与驱动杆一起围绕其纵向轴线相对于第二或第一阻尼元件中的另一个旋转。

公开(公告)号：US20160011048A1

公开(公告)日：2016-01-14

申请号：US14794316

申请日：2015-07-08

Applicant: TECAN Trading AG

Inventor： Lutz NIGGL ,  Andreas ERLBACHER ,  Frank MÜNCHOW

IPC: G01J3/18 ,  G01J3/42 ,  G01J3/06

CPC classification number: G01J3/18 ,  G01J3/06 ,  G01J3/42 ,  G01J2003/1204 ,  G01J2003/1213 ,  G01J2003/1217 ,  G01N21/253 ,  G01N21/31 ,  G01N35/028 ,  G01N2021/3174 ,  G01N2201/084

Abstract: A spectrometer (1) comprises a light source (2), a monochromator (3) with at least one diffraction grating (4), a monochromator housing (5), an order sorting filter (7), a microplate receptacle (12) and a controller (6). The order sorting filter (7) of the spectrometer (1) comprises a substrate (23), a first optical thin film (24) and a second optical thin film (25), wherein, in a spatially partly overlapping and interference-free manner, the first optical thin film (24) is arranged on a first surface (26) and the second optical thin film (25) is arranged on a second surface (27) of the substrate (23). A spectrometer (1) equipped with a respective order sorting filter is used in a scanning method for detecting the absorption spectrum of samples examined in wells (14) of microplates (13).

Abstract translation: 光谱仪（1）包括光源（2），具有至少一个衍射光栅（4）的单色仪（3），单色仪外壳（5），订单分类过滤器（7），微板容器（12）和 控制器（6）。 光谱仪（1）的顺序分选滤光器（7）包括基板（23），第一光学薄膜（24）和第二光学薄膜（25），其中在空间上部分重叠和无干扰的方式 第一光学薄膜（24）布置在第一表面（26）上，第二光学薄膜（25）被布置在基板（23）的第二表面（27）上。 在用于检测在微孔板（13）的孔（14）中检测的样品的吸收光谱的扫描方法中，使用装备有相应的顺序分选过滤器的光谱仪（1）。

公开(公告)号：US20160003866A1

公开(公告)日：2016-01-07

申请号：US14761726

申请日：2014-01-13

Applicant: Ecole Polytechnique ,  Centre National de la Recherche Scientifique

Inventor： Marc Chaigneau ,  Akli Karar ,  Bernard Drevillon ,  Razvigor Ossikovski

IPC: G01Q10/00 ,  G01J3/06 ,  G01J3/44 ,  G01Q40/00

CPC classification number: G01Q10/00 ,  G01J3/06 ,  G01J3/44 ,  G01N21/658 ,  G01Q10/045 ,  G01Q20/04 ,  G01Q30/02 ,  G01Q40/00 ,  G01Q60/04 ,  G01Q60/16 ,  G01Q60/26

Abstract: The present invention relates to a multimode local probe microscope having a resonator (1), a first electrode (9), and a second electrode (8), an excitation source adapted to generate mechanical resonance in the resonator, a metal tip (4) fastened to the resonator, movement means for imparting relative movement between the local probe and a sample and adapted to bring the end of the tip to within a distance Z lying in the range 0 to 100 nm, and detector means for detecting at least one electrical signal representative of friction forces at the terminals of said electrodes (8, 9). According to the invention, said metal tip (4) is electrically connected to said output second electrode (9) and the microscopy apparatus includes amplifier and filter means for amplifying and filtering signals relating to the friction forces and to the tunnelling current in a single electronic circuit, and means for regulating the distance Z between the end of the tip and the surface of the sample.

Abstract translation: 本发明涉及具有共振器（1），第一电极（9）和第二电极（8）的多模式局部探针显微镜，适于在谐振器中产生机械共振的激发源，金属尖端（4） 固定在谐振器上的移动装置，用于在局部探针和样品之间施加相对运动并适于使尖端的端部处于位于0至100nm范围内的距离Z内;以及检测器装置，用于检测至少一个电气 代表在所述电极（8,9）的端子处的摩擦力的信号。 根据本发明，所述金属端头（4）电连接到所述输出第二电极（9），并且所述显微镜装置包括放大器和滤波器装置，用于放大和滤波与单个电子装置中的摩擦力和隧道电流有关的信号 电路和用于调节尖端端部和样品表面之间的距离Z的装置。

公开(公告)号：US09207118B2

公开(公告)日：2015-12-08

申请号：US13429096

申请日：2012-03-23

Applicant: Robert J. Faus ,  Leonid G. Feldman ,  Alexander F. H. Goetz

Inventor： Robert J. Faus ,  Leonid G. Feldman ,  Alexander F. H. Goetz

IPC: G01N21/25 ,  G01J3/28 ,  G01J3/06

CPC classification number: G01J3/28 ,  G01J3/06

Abstract: A system and method for determining bias in a spectrometer is described. One embodiment includes a method for determining bias in a spectrometer system, the method comprising over-scanning a grating in a near-zero-response wavelength range; and determining a bias based on the over-scanning. This methodology allows for over-scanning a grating in a near-zero-response wavelength range as a substitute for using shutters or other mechanisms to block light from entering a detector in the system.

Abstract translation: 描述了用于确定光谱仪中偏压的系统和方法。 一个实施例包括用于确定光谱仪系统中的偏压的方法，所述方法包括对接近零响应波长范围的光栅进行过扫描; 以及基于过扫描来确定偏差。 该方法允许对接近零响应波长范围的光栅进行过扫描，以代替使用百叶窗或其他机构阻挡光进入系统中的检测器。

公开(公告)号：US20150316413A1

公开(公告)日：2015-11-05

申请号：US14795954

申请日：2015-07-10

Applicant: SciAps, Inc.

Inventor： David Day

IPC: G01J3/02 ,  G01J3/443

CPC classification number: G01J3/443 ,  G01J3/0208 ,  G01J3/0237 ,  G01J3/0272 ,  G01J3/06 ,  G01J3/44 ,  H01L22/26

Abstract: An analysis system (e.g., LIBS) includes a laser source generating a laser beam, a movable optic configured to move said laser beam to multiple locations on a sample, and a spectrometer responsive to photons emitted by the sample at those locations and having an output. A controller is responsive to a trigger signal and is configured in a moving spot cycle to adjust the moveable optic, activate the laser source sequentially generating photons at multiple locations on the sample, and process the spectrometer output at each location.

Abstract translation: 分析系统（例如，LIBS）包括产生激光束的激光源，配置成将所述激光束移动到样品上的多个位置的可移动光学器件，以及响应于在那些位置的样品发射的光子的光谱仪，并具有输出 。 控制器响应于触发信号并且被配置成移动点周期以调整可移动光学元件，激活激光源在样本上的多个位置顺序地生成光子，并且处理每个位置处的光谱仪输出。

公开(公告)号：US09176319B2

公开(公告)日：2015-11-03

申请号：US12052984

申请日：2008-03-21

Applicant: Brett Eugene Bouma ,  Reza Motaghiannezam ,  Guillermo J. Tearney

Inventor： Brett Eugene Bouma ,  Reza Motaghiannezam ,  Guillermo J. Tearney

IPC: G02B26/12 ,  G01J3/02 ,  G01J3/06 ,  G01J3/10 ,  G01J3/18 ,  G01J3/433 ,  G02B26/00 ,  G01J3/12 ,  G01N21/39 ,  H01S5/14

CPC classification number: G02B26/12 ,  G01J3/02 ,  G01J3/0208 ,  G01J3/021 ,  G01J3/0218 ,  G01J3/06 ,  G01J3/10 ,  G01J3/18 ,  G01J3/4338 ,  G01J2003/1286 ,  G01N21/39 ,  G02B26/002 ,  H01S5/141 ,  H01S5/143 ,  H01S5/146

Abstract: Exemplary systems and methods for filtering an electromagnetic radiation can be provided. For example, at least one first arrangement can be provided which is capable of receiving at least one first electro-magnetic radiation and forwarding at least one second electro-magnetic radiation at different angles with respect to a direction of incidence of the first electro-magnetic radiation. At least one second wavelength dispersion arrangement can be provided which is configured to receive the second electro-magnetic radiation, forward at least one third electro-magnetic radiation to the first arrangement and further receive at least one fourth electro-magnetic radiation. The third electro-magnetic radiation can be based on the second electro-magnetic radiation, and the fourth electro-magnetic radiation can be based on the third electro-magnetic radiation. For example, the second arrangement can be configured to forward the second electro-magnetic radiation at different angles with respect to a direction of incidence of the at least one particular electro-magnetic radiation. Exemplary embodiments of methods can be provided to implement such exemplary techniques.

Abstract translation: 可以提供用于过滤电磁辐射的示例性系统和方法。 例如，可以提供至少一个第一布置，其能够接收至少一个第一电磁辐射并且相对于第一电磁场的入射方向以不同的角度转发至少一个第二电磁辐射 辐射。 可以提供至少一个第二波长色散布置，其被配置为接收第二电磁辐射，将至少一个第三电磁辐射向前延伸到第一布置并进一步接收至少一个第四电磁辐射。 第三电磁辐射可以基于第二电磁辐射，第四电磁辐射可以基于第三电磁辐射。 例如，第二布置可以被配置为相对于至少一个特定电磁辐射的入射方向以不同的角度转发第二电磁辐射。 可以提供方法的示例性实施例来实现这种示例性技术。