公开(公告)号：US20050198023A1

公开(公告)日：2005-09-08

申请号：US11056733

申请日：2005-02-11

Applicant: Christina James ,  Mark Brighton ,  Lisa Nathan ,  Ethan Bradford ,  David Kay

Inventor： Christina James ,  Mark Brighton ,  Lisa Nathan ,  Ethan Bradford ,  David Kay

IPC: G06F17/22 ,  G06F17/27 ,  G06F7/00

CPC classification number: G06F3/0236 ,  G06F17/276 ,  Y10S707/99931 ,  Y10S707/99932 ,  Y10S707/99933 ,  Y10S707/99934 ,  Y10S707/99935 ,  Y10S707/99936

Abstract: The invention provides a process for selecting and ordering one or more sets of linguistic objects. The invention orders a current list of items for selection that comprises a first list of one or more items of a first language and a second list of one or more items of a second language, the current list of items being displayed in an order based on the first language having a priority over the second language. In response to a user selection of one item from the second list, the invention changes a priority for ordering a subsequent list of items to order the subsequent list of items based on the second language having a priority over the first language.

Abstract translation: 本发明提供了一种用于选择和排序一组或多组语言对象的过程。 本发明命令包括第一语言的一个或多个项目的第一列表和第二语言的一个或多个项目的第二列表的当前列表，该当前项目列表以基于 第一语言优先于第二语言。 响应于用户从第二列表中选择一个项目，本发明改变了排序随后的项目列表的优先级，以便基于具有优先于第一语言的优先级的第二语言来订购随后的项目列表。

公开(公告)号：US20050017954A1

公开(公告)日：2005-01-27

申请号：US10866634

申请日：2004-06-10

Applicant: David Kay ,  Ethan Bradford ,  Pim van Meurs ,  Peter Peddie

Inventor： David Kay ,  Ethan Bradford ,  Pim van Meurs ,  Peter Peddie

IPC: G06F3/023 ,  G06F17/27 ,  G09G5/00

CPC classification number: G06F3/0233 ,  G06F3/0235 ,  G06F3/0237 ,  G06F17/276

Abstract: The invention concerns user entry of information into a system with an input device. A scheme is provided in which an entire word that a user wants to enter is predicted after the user enters a specific symbol, such as a space character. If the user presses an ambiguous key thereafter, rather than accept the prediction, the selection list is reordered. For example, a user enters the phrase “Lets run to school. Better yet, lets drive to “.””” After the user presses the space, after first entering the second occurrence of the word “to,” the system predicts that the user is going to enter the word “school” based on the context in which the user has entered that word in the past. Should the user enter an ambiguous key after the space, then a word list which contains the word “school” is reordered and other options are made available to the user. The invention can also make predictions on context, such as the person to whom the message is sent, the person writing the message, the day of the week, the time of the week, etc. Other embodiments of the invention contemplate anticipation of user actions, as well as words, such as a user action in connection with menu items, or a user action in connection with form filling.

Abstract translation: 本发明涉及用户通过输入设备将信息输入系统。 提供一种方案，其中在用户输入诸如空格字符的特定符号之后预测用户想要输入的整个单词。 如果用户之后按下模糊键，而不是接受预测，则选择列表被重新排序。 例如，用户输入短语“让我们跑到学校，更好，让我们开车去”。“”“用户按住空格后，首先进入第二次出现的单词”to“后，系统预测 用户将根据用户在过去输入该单词的上下文输入单词“school”，如果用户在空格之后输入模糊键，则重新排序包含单词“school”的单词列表 本发明还可以对上下文进行预测，诸如发送消息的人，撰写消息的人，星期几，星期几等。 本发明的其他实施例考虑了对用户动作的预期，以及诸如与菜单项相关的用户动作或与表单填充有关的用户动作的单词。

公开(公告)号：US06846928B2

公开(公告)日：2005-01-25

申请号：US10389707

申请日：2003-03-14

Applicant: David Bebbington ,  Hayley Binch ,  Jean-Damien Charrier ,  Simon Everitt ,  Julian M. C. Golec ,  David Kay ,  Ronald Knegtel ,  Andrew Miller ,  Francoise Pierard ,  Albert C. Pierce

Inventor： David Bebbington ,  Hayley Binch ,  Jean-Damien Charrier ,  Simon Everitt ,  Julian M. C. Golec ,  David Kay ,  Ronald Knegtel ,  Andrew Miller ,  Francoise Pierard ,  Albert C. Pierce

IPC: A61P35/00 ,  C07D403/12 ,  C07D413/12 ,  C07D417/12 ,  C07D471/04 ,  C07D487/04 ,  C07D239/28

CPC classification number: C07D403/12 ,  C07D413/12 ,  C07D417/12 ,  C07D471/04 ,  C07D487/04

Abstract: The present invention relates to compounds useful as inhibitors of protein kinases. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders.

Abstract translation: 本发明涉及可用作蛋白激酶抑制剂的化合物。 本发明还提供包含所述化合物的药学上可接受的组合物和使用该组合物治疗各种疾病，病症或病症的方法。

公开(公告)号：US20050004110A1

公开(公告)日：2005-01-06

申请号：US09952878

申请日：2001-09-14

Applicant: David Bebbington ,  Hayley Binch ,  Ronald Knegtel ,  Julian Golec ,  Sanjay Patel ,  Jean- Damien Charrier ,  David Kay ,  Robert Davies

Inventor： David Bebbington ,  Hayley Binch ,  Ronald Knegtel ,  Julian Golec ,  Sanjay Patel ,  Jean- Damien Charrier ,  David Kay ,  Robert Davies

IPC: C07D403/12 ,  A61K31/415 ,  A61K31/437 ,  A61K31/4709 ,  A61K31/4725 ,  A61K31/501 ,  A61K31/5025 ,  A61K31/506 ,  A61K31/517 ,  A61K31/519 ,  A61K31/52 ,  A61K31/53 ,  A61K31/5377 ,  A61K31/541 ,  A61K31/55 ,  A61K45/00 ,  A61P1/16 ,  A61P3/08 ,  A61P3/10 ,  A61P3/14 ,  A61P5/00 ,  A61P9/00 ,  A61P9/10 ,  A61P11/06 ,  A61P17/06 ,  A61P19/00 ,  A61P19/02 ,  A61P19/10 ,  A61P25/18 ,  A61P25/28 ,  A61P29/00 ,  A61P31/12 ,  A61P35/00 ,  A61P35/02 ,  A61P37/02 ,  A61P37/06 ,  A61P37/08 ,  A61P43/00 ,  C07D239/26 ,  C07D239/36 ,  C07D239/70 ,  C07D239/88 ,  C07D401/12 ,  C07D401/14 ,  C07D403/14 ,  C07D405/14 ,  C07D407/14 ,  C07D409/14 ,  C07D413/14 ,  C07D417/14 ,  C07D471/04 ,  C07D473/16 ,  C07D475/10 ,  C07D487/04 ,  C07D491/04 ,  C07D491/044 ,  C07D491/048 ,  C07D491/052 ,  C07D491/107 ,  C07D491/113 ,  C07D491/20 ,  C07D493/04 ,  C07D495/04 ,  C07D498/04 ,  C07D513/04 ,  C07D521/00 ,  C07

CPC classification number: C07D401/14 ,  C07D231/12 ,  C07D233/56 ,  C07D249/08 ,  C07D401/12 ,  C07D403/12 ,  C07D403/14 ,  C07D405/14 ,  C07D407/14 ,  C07D409/14 ,  C07D417/14 ,  C07D471/04 ,  C07D473/16 ,  C07D487/04 ,  C07D491/04 ,  C07D493/04 ,  C07D495/04 ,  C07D513/04

Abstract: This invention describes novel pyrazole compounds of formula III: wherein Ring D is a 5-7 membered monocyclic ring or 8-10 membered bicyclic ring selected from aryl, heteroaryl, heterocyclyl or carbocyclyl; Rx and Ry are taken together with their intervening atoms to form a fused, unsaturated or partially unsaturated, 5-8 membered carbocyclo ring; and R2 and R2′ are as described in the specification. The compounds are useful as protein kinase inhibitors, especially as inhibitors of aurora-2 and GSK-3, for treating diseases such as cancer, diabetes and Alzheimer's disease.

Abstract translation: 本发明描述了式III的新型吡唑化合物：其中环D是选自芳基，杂芳基，杂环基或碳环基的5-7元单环或8-10元双环; R x和R y与它们的插入原子一起形成稠合的，不饱和的或部分不饱和的5-8元碳环; 和R 2和R 2'如说明书中所述。 这些化合物可用作蛋白激酶抑制剂，特别是作为用于治疗诸如癌症，糖尿病和阿尔茨海默病的疾病的极光-2和GSK-3的抑制剂。

公开(公告)号：US06653301B2

公开(公告)日：2003-11-25

申请号：US10027001

申请日：2001-12-19

Applicant: David Bebbington ,  Jean-Damien Charrier ,  Robert Davies ,  Julian M. C. Golec ,  David Kay ,  Ronald Knegtel ,  Sanjay Patel

Inventor： David Bebbington ,  Jean-Damien Charrier ,  Robert Davies ,  Julian M. C. Golec ,  David Kay ,  Ronald Knegtel ,  Sanjay Patel

IPC: A61K3133

CPC classification number: C07D403/14 ,  C07D231/12 ,  C07D233/56 ,  C07D249/08 ,  C07D401/12 ,  C07D401/14 ,  C07D403/12 ,  C07D405/14 ,  C07D407/14 ,  C07D409/14 ,  C07D417/14 ,  C07D471/04 ,  C07D473/16 ,  C07D487/04 ,  C07D491/04 ,  C07D493/04 ,  C07D495/04 ,  C07D513/04

Abstract: This invention describes novel pyrazole compounds of formula IIa: wherein R1 is T-Ring D, wherein Ring D is a 5-7 membered monocyclic ring or 8-10 membered bicyclic ring selected from aryl, heteroaryl, heterocyclyl or carbocyclyl; Rx and Ry are taken together with their intervening atoms to form a fused, unsaturated or partially unsaturated, 5-7 membered ring having 0-3 heteroatoms; and R2 and R2 are as described in the specification. The compounds are useful as protein kinase inhibitors, especially as inhibitors of Aurora-2 and GSK-3, for treating diseases such as cancer, diabetes and Alzheimer's disease.

Abstract translation: 本发明描述了式IIa的新型吡唑化合物：其中R 1是T环D，其中环D是5-7元单环或选自芳基，杂芳基，杂环基或碳环基的8-10元双环; R x和R y与它们的插入原子一起形成具有0-3个杂原子的稠合的，不饱和的或部分不饱和的5-7元环; R 2和R 2如说明书中所述。 这些化合物可用作蛋白激酶抑制剂，特别是作为Aurora-2和GSK-3的抑制剂用于治疗诸如癌症，糖尿病和阿尔茨海默病的疾病。

公开(公告)号：US06564624B2

公开(公告)日：2003-05-20

申请号：US09924873

申请日：2001-08-08

Applicant: Yingjie Lin ,  Han-Sheng Lee ,  Su-Chee Simon Wang ,  David Kay Lambert

Inventor： Yingjie Lin ,  Han-Sheng Lee ,  Su-Chee Simon Wang ,  David Kay Lambert

IPC: G01M1500

CPC classification number: G01N33/2829 ,  G01N27/226

Abstract: A sensor and method for measuring the volatility of liquid gasoline by estimating its driveability index includes a sensing element having an interdigitated array of electrically conducting capacitor plates arranged to retain a predetermined volume of gasoline, the volatility of which is to be measured. The sensing element is mounted in a vehicle to be in contact with the flow of gasoline while the engine is running so that a volume certain of gasoline is drawn between and remains within the electrically conducting plates when the engine is turned off. The sensing element is connected to circuitry used to measure the change in capacitance of the sensing element as a function of time while simultaneously measuring the temperature change of the sensing element as the volume of gasoline retained by the sensing element is evaporated over time. The measurements obtained by the circuitry are used in estimating the drivability index of the gasoline.

Abstract translation: 用于通过估计其可驾驶性指数来测量液体汽油的挥发性的传感器和方法包括传感元件，其具有布置成保持预定体积的汽油的交叉排列的导电电容器板，其挥发性将被测量。 当发动机运转时，感测元件安装在车辆中以与汽油流接触，使得当发动机关闭时，一定量的汽油被吸入导电板内并保持在导电板内。 感测元件连接到用于测量感测元件的电容变化的电路作为时间的函数，同时随着时间的推移，感测元件保持的汽油体积蒸发，同时测量感测元件的温度变化。 通过电路获得的测量值用于估计汽油的驾驶性能指数。

公开(公告)号：US5709082A

公开(公告)日：1998-01-20

申请号：US654049

申请日：1996-05-28

Applicant: Stephen Joel Harris ,  David Kay Lambert

Inventor： Stephen Joel Harris ,  David Kay Lambert

IPC: G01N21/05 ,  G01N21/35 ,  F01N3/28

CPC classification number: G01N21/3504 ,  G01N21/05

Abstract: The invention includes an on-board diagnostic system for monitoring exhaust gas from an automotive combustion engine and includes a sample port connected to the exhaust piping, preferably downstream from the catalytic converter. The exhaust port leads to a sample cell to which an infrared spectrometry system is operably connected to measure the concentration of hydrocarbons in the sample cell. An air pump is connected to the exhaust port and communicates with the sample cell. The air pump is operated to continuously purge the sample cell by pushing small amounts of clean air through the sample cell into the exhaust.

Abstract translation: 本发明包括用于监测来自汽车内燃机的废气的车载诊断系统，并且包括连接到排气管道的抽样端口，优选地在催化转化器的下游。 排气口通向可操作地连接红外光谱系统的样品池，以测量样品池中的烃浓度。 空气泵连接到排气口并与样品池连通。 操作空气泵，通过将少量清洁空气通过样品池排入排气口来连续吹扫样品池。

公开(公告)号：US5661006A

公开(公告)日：1997-08-26

申请号：US308872

申请日：1994-09-19

Applicant: Thomas David Kay Brown ,  Brian Colin Horsburgh

Inventor： Thomas David Kay Brown ,  Brian Colin Horsburgh

IPC: A61K39/00 ,  A61K39/215 ,  A61P31/12 ,  C07K14/165 ,  C12N5/10 ,  C12N7/00 ,  C12N15/09 ,  C12N15/50 ,  C12N15/86 ,  C12N15/863 ,  C12P21/02 ,  C12R1/91 ,  C12R1/92 ,  C07H21/00 ,  C12N15/06 ,  C12N15/63

CPC classification number: C07K14/005 ,  C12N15/86 ,  A61K39/00 ,  C12N2710/24143 ,  C12N2770/20022

Abstract: The invention is related to a nucleic acid sequence &coding a Canine coronavirus (CCV) spike protein. Such a protein can be used for the immunization of dogs against CCV infection. The nucleic acid sequence encoding the CCV spike protein can be applied for the preparation of the spike protein by means of genetic engineering techniques or can be applied for the preparation of vector vaccines.

Abstract translation: 本发明涉及编码犬冠状病毒（CCV）刺突蛋白的核酸序列。 这样的蛋白质可以用于狗免疫CCV感染。 编码CCV尖峰蛋白的核酸序列可以通过基因工程技术应用于尖峰蛋白的制备，或者可以用于制备载体疫苗。

公开(公告)号：USD258536S

公开(公告)日：1981-03-10

申请号：US907260

申请日：1978-05-18

Applicant: David Kay

Designer： David Kay

公开(公告)号：US4084442A

公开(公告)日：1978-04-18

申请号：US744895

申请日：1976-11-24

Applicant: David Kay

Inventor： David Kay

IPC: B01F15/00 ,  G01N11/00 ,  G01N33/00 ,  G01N15/00

CPC classification number: B01F15/00207 ,  G01N11/00 ,  G01N2033/0091

Abstract: The end-point of an operation in which the flow properties of particulate material are altered during agitation is determined using a probe inserted into the vessel in which agitation occurs and which deflects when hit by material being agitated and detecting when the amplitude and/or frequency of the deflections of the probe changes to a given level.

Abstract translation: 搅拌期间颗粒材料的流动性质改变的操作的终点是使用插入到容器中的探针来确定的，其中发生搅动，当被搅拌的材料撞击时偏转，并且检测何时振幅和/或频率 探头的偏转变化到给定的水平。