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    METHOD FOR PRODUCING ALBICANOL AND/OR DRIMENOL
    42.
    发明申请
    METHOD FOR PRODUCING ALBICANOL AND/OR DRIMENOL 有权

    公开(公告)号：US20220186265A1

    公开(公告)日：2022-06-16

    申请号：US17673465

    申请日：2022-02-16

    Applicant: FIRMENICH SA

    Inventor： Michel Schalk ,  Pauline Anziani ,  Christian Goerner ,  Daniel Solis Escalante

    IPC: C12P7/02 ,  C12N9/88

    Abstract: Described herein is a method of producing a drimane sesquiterpene such as albicanol, drimenol and/or derivatives thereof by contacting at least one polypeptide with farnesyl diphosphate (FPP) with a polypeptide including a Haloacid dehalogenase (HAD)-like hydrolase domain and having bifunctional terpene synthase activity. The method may be performed in vitro or in vivo. Also described herein are amino acid sequences of polypeptides useful in the methods and nucleic acids encoding the polypeptides described. The described method further provides host cells or organisms genetically modified to express the polypeptides and useful to produce a drimane sesquiterpene such as albicanol, drimenol and/or derivatives thereof.

    Fruity odorant
    43.
    发明授权
    Fruity odorant 有权

    公开(公告)号：US11352314B2

    公开(公告)日：2022-06-07

    申请号：US16922799

    申请日：2020-07-07

    Applicant: FIRMENICH SA

    Inventor： Christian Vial ,  Roger Leslie Snowden

    IPC: C07C69/67 ,  C11B9/00

    Abstract: The present invention relates to compounds of formula (I) that are useful as perfuming ingredients of the fruity type. Formula (I) is in the form of any one of its stereoisomers or of a mixture thereof, wherein R1 represents a C1-3 alkyl or alkenyl group, R2 represents a methyl or ethyl group, R3 represents a C1-4 alkyl or alkenyl group, and the compound (I) has from 8 to 12 carbon atoms.

    Process for the preparation of cis-alpha,beta substituted cyclopentanones
    45.
    发明授权
    Process for the preparation of cis-alpha,beta substituted cyclopentanones 有权

    公开(公告)号：US11339113B2

    公开(公告)日：2022-05-24

    申请号：US17273357

    申请日：2019-12-16

    Applicant: FIRMENICH SA

    Inventor： Denis Jacoby ,  Lucia Bonomo

    IPC: C07C67/327 ,  C07C69/716

    Abstract: Described herein is a process for the preparation of a mixture of compounds of formula having a weight ratio of the cis-diastereomers to trans-diastereoisomers higher than 1:1, where R1 represents a C1-8 alkyl group, a C2-8 alkenyl group or a C2-8 alkynyl group, each optionally substituted with one or two of a C1-4 alkyl alkoxy ether group and/or a C1-4 alkyl carboxylester group and R2 represents a C1-6 alkyl, a C2-6 alkenyl or a C2-6 alkynyl group, each optionally substituted with a C1-4 alkyl alkoxy ether group, a carboxylic acid group or a C1-4 alkyl carboxylester group and compounds suitable in the process.

    Method for producing albicanol and/or drimenol
    47.
    发明授权
    Method for producing albicanol and/or drimenol 有权

    公开(公告)号：US11293037B2

    公开(公告)日：2022-04-05

    申请号：US16618737

    申请日：2018-05-31

    Applicant: FIRMENICH SA

    Inventor： Michel Schalk ,  Pauline Anziani ,  Christian Goerner ,  Daniel Solis Escalante

    IPC: C12P7/02 ,  C12N9/88

    Abstract: Described herein is a method of producing a drimane sesquiterpene such as albicanol, drimenol and/or derivatives thereof by contacting at least one polypeptide with farnesyl diphosphate (FPP) with a polypeptide comprising a Haloacid dehalogenase (HAD)-like hydrolase domain and having bifunctional terpene synthase activity. The method may be performed in vitro or in vivo. Also described herein are amino acid sequences of polypeptides useful in the methods and nucleic acids encoding the polypeptides described. The described method further provides host cells or organisms genetically modified to express the polypeptides and useful to produce a drimane sesquiterpene such as albicanol, drimenol and/or derivatives thereof.

    Sweetened Dairy Compositions
    48.
    发明申请
    Sweetened Dairy Compositions 有权

    公开(公告)号：US20220079178A1

    公开(公告)日：2022-03-17

    申请号：US17517848

    申请日：2021-11-03

    Applicant: Firmenich SA

    Inventor： Mazen Moustafa ,  Jean-Luc Gelin ,  April Wong

    IPC: A23C9/12 ,  A23C9/13

    Abstract: The disclosure relates generally to flavor-modified dairy compositions. In some embodiments, the flavor-modified dairy compositions comprise hydrolysis products of lactose (e.g., glucose and galactose), a flavor modifier (such as a terpene-based compound), or any combinations thereof. In some other aspects, the disclosure provides uses of a combination of lactase and a flavor modifier (such as a terpene-based compound) to modify the flavor of a dairy composition. In some related aspects, the disclosure provides methods of modifying the flavor of a dairy composition, wherein the methods include introducing a lactase and a flavor modifier (such as a terpene-based compound) to a dairy composition.

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