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41.发明申请公开(公告)号：US20050277115A1
公开(公告)日：2005-12-15
申请号：US10454437
申请日：2003-06-04
摘要： Isolated nucleic acid molecules, designated HA nucleic acid molecules, which encode novel HA proteins from Corynebacterium glutamicum are described. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing HA nucleic acid molecules, and host cells into which the expression vectors have been introduced. The invention still further provides isolated HA proteins, mutated HA proteins, fusion proteins, antigenic peptides and methods for the improvement of production of a desired compound from C. glutamicum based on genetic engineering of HA genes in this organism.
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公开(公告)号：US06962989B1
公开(公告)日：2005-11-08
申请号：US09605703
申请日：2000-06-27
CPC分类号： C07K14/34 , C07H21/02 , C07H21/04 , C12P13/04 , C12P13/06 , C12P13/08 , C12P13/10 , C12P13/12 , C12P13/14 , C12P13/20 , C12P13/222 , C12P13/225 , C12P13/227 , C12P13/24
摘要： Isolated nucleic acid molecules, designated MCP nucleic acid molecules, which encode novel MCP proteins from Corynebacterium glutamicum are described. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing MCP nucleic acid molecules, and host cells into which the expression vectors have been introduced. The invention still further provides isolated MCP proteins, mutated MCP proteins, fusion proteins, antigenic peptides and methods for the improvement of production of a desired compound from C. glutamicum based on genetic engineering of MCP genes in this organism.
摘要翻译： 描述了编码来自谷氨酸棒杆菌的新型MCP蛋白质的分离的核酸分子，命名为MCP核酸分子。 本发明还提供反义核酸分子，含有MCP核酸分子的重组表达载体，以及引入了表达载体的宿主细胞。 本发明还进一步提供了分离的MCP蛋白，突变的MCP蛋白，融合蛋白，抗原肽和用于根据该生物体中MCP基因的遗传工程改进从谷氨酸棒球菌生产所需化合物的方法。
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公开(公告)号：US20050153402A1
公开(公告)日：2005-07-14
申请号：US11006098
申请日：2004-12-06
IPC分类号： C07K14/34 , C12N9/00 , C12N9/18 , C12N9/90 , C12P13/04 , C07H21/04 , C12N1/21 , C12N15/74 , C12Q1/68
CPC分类号： C12P7/6472 , C07K14/34 , C07K2319/00 , C12N9/00 , C12N9/18 , C12N9/90 , C12P7/6409 , C12P7/6427 , C12P7/6463 , C12P13/04 , C12P17/10
摘要： Isolated nucleic acid molecules, designated MR nucleic acid molecules, which encode novel MR proteins from Corynebacterium glutamicum are described. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing MR nucleic acid molecules, and host cells into which the expression vectors have been introduced. The invention still further provides isolated MR proteins, mutated MR proteins, fusion proteins, antigenic peptides and methods for the improvement of production of a desired compound from C. glutamicum based on genetic engineering of MR genes in this organism.
摘要翻译： 描述了编码来自谷氨酸棒杆菌的新型MR蛋白质的分离的核酸分子，命名为MR核酸分子。 本发明还提供反义核酸分子，含有MR核酸分子的重组表达载体和已经引入表达载体的宿主细胞。 本发明还进一步提供了分离的MR蛋白，突变的MR蛋白，融合蛋白，抗原肽以及用于基于该生物体中MR基因的遗传工程改进谷氨酸棒球菌的所需化合物生产的方法。
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44.发明授权Corynebacterium glutamicum genes encoding phosphoenolpyruvate: sugar phosphotransferase system proteins 有权谷氨酸棒杆菌基因编码磷酸烯醇丙酮酸：糖磷酸转移酶系统蛋白公开(公告)号：US06884614B1
公开(公告)日：2005-04-26
申请号：US09604231
申请日：2000-06-27
IPC分类号： C07H21/04 , C12N1/12 , C12N1/20 , C12N1/21 , C12N9/00 , C12N9/10 , C12N9/12 , C12N15/00 , C12N15/74 , C12P1/04 , C12P13/04 , C12P21/06
CPC分类号： C12N9/1205 , C07K14/34 , C12N9/00 , C12N9/1223 , C12P1/04 , C12P13/04 , C12R1/15 , C12Y207/01069
摘要： Isolated nucleic acid molecules, designated PTS nucleic acid molecules, which encode novel PTS proteins from Corynebacterium glutamicum are described. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing PTS nucleic acid molecules, and host cells into which the expression vectors have been introduced. The invention still further provides isolated PTS proteins, mutated PTS proteins, fusion proteins, antigenic peptides and methods for the improvement of production of a desired compound from C. glutamicum based on genetic engineering of PTS genes in this organism.
摘要翻译： 描述了编码来自谷氨酸棒杆菌的新型PTS蛋白的分离的核酸分子，命名为PTS核酸分子。 本发明还提供反义核酸分子，含有PTS核酸分子的重组表达载体，以及引入了表达载体的宿主细胞。 本发明还进一步提供了基于该生物体中PTS基因的遗传工程的分离的PTS蛋白，突变的PTS蛋白，融合蛋白，抗原肽和用于从谷氨酸棒状病毒从谷氨酸棒球菌生产所需化合物的方法。
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公开(公告)号：US06878536B2
公开(公告)日：2005-04-12
申请号：US10076157
申请日：2002-02-15
申请人： Markus Pompejus , Harald Seulberger , Hans Wolfgang Höffken , Jose Luis Revuelta Doval , Alberto Jimenez , Maria Angeles Santos Garcia
发明人： Markus Pompejus , Harald Seulberger , Hans Wolfgang Höffken , Jose Luis Revuelta Doval , Alberto Jimenez , Maria Angeles Santos Garcia
IPC分类号： C12N15/09 , C07K14/39 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N9/00 , C12N9/02 , C12N9/04 , C12N9/10 , C12N9/12 , C12N15/00 , C12N15/52 , C12N15/53 , C12N15/80 , C12P19/28 , C12P25/00 , C12R1/645
CPC分类号： C12N9/93 , C12N9/0006 , C12N9/1077 , C12N9/1235 , C12P25/00
摘要： Genes of purine biosynthesis from Ashbya gossypii are used in microbial riboflavin synthesis.
摘要翻译： 用于生物合成核黄素的嘌呤生物合成基因。
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公开(公告)号：US20050014235A1
公开(公告)日：2005-01-20
申请号：US10495291
申请日：2002-11-11
申请人： Oskar Zelder , Markus Pompejus , Hartwig Schroder , Burkhard Kroger , Corrina Klopprogge , Gregor Haberhauer
发明人： Oskar Zelder , Markus Pompejus , Hartwig Schroder , Burkhard Kroger , Corrina Klopprogge , Gregor Haberhauer
CPC分类号： C12N9/0006 , C07K14/415
摘要： Isolated nucleic acid molecule, coding for a polypeptide having the amino acid sequence referred to in each case in Table 1/column 2, wherein the nucleic acid molecule in the amino acid position indicated in Table 1/column 4 encodes a proteinogenic amino acid different from the particular amino acid indicated in Table 1/column 5 in the same row.
摘要翻译： 分离的核酸分子，编码具有表1 /栏2中各种情况的氨基酸序列的多肽，其中表1 /第4列所示氨基酸位置的核酸分子编码不同于 在同一行的表1 /列5中所示的特定氨基酸。
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公开(公告)号：US20050014233A1
公开(公告)日：2005-01-20
申请号：US10494836
申请日：2002-10-31
申请人： Oskar Zelder , Markus Pompejus , Hartwig Schroder , Burkhard Kroger , Corinna Klopprogge , Gregor Haberhauer
发明人： Oskar Zelder , Markus Pompejus , Hartwig Schroder , Burkhard Kroger , Corinna Klopprogge , Gregor Haberhauer
CPC分类号： C07K14/34 , C12N9/00 , C12N9/0006 , C12P13/08
摘要： The invention relates to novel nucleic acid molecules, to the use thereof for constructing genetically improved microorganisms and to methods for preparing fine chemicals, in particular amino acids, with the aid of said genetically improved microorganisms.
摘要翻译： 本发明涉及新颖的核酸分子，其用于构建遗传改良微生物的用途以及借助所述遗传改良的微生物制备精细化学品，特别是氨基酸的方法。
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48.发明授权Genes of purine biosynthesis from Ashbya gossypii and the use thereof in microbial riboflavin synthesis 失效来自棉铃癣菌的嘌呤生物合成基因及其在微生物核黄素合成中的应用公开(公告)号：US06391603B1
公开(公告)日：2002-05-21
申请号：US09212247
申请日：1998-12-16
申请人： Markus Pompejus , Harald Seulberger , Hans Wolfgang Höffken , Jose Luis Revuelta Doval , Alberto Jimenez , Maria Angeles Santos Garcia
发明人： Markus Pompejus , Harald Seulberger , Hans Wolfgang Höffken , Jose Luis Revuelta Doval , Alberto Jimenez , Maria Angeles Santos Garcia
IPC分类号： C12N910
CPC分类号： C12N9/93 , C12N9/0006 , C12N9/1077 , C12N9/1235 , C12P25/00
摘要： Genes of purine biosynthesis from Ashbya gossypii are used in microbial riboflavin synthesis.
摘要翻译： 用于生物合成核黄素的嘌呤生物合成基因。
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公开(公告)号：US07355031B2
公开(公告)日：2008-04-08
申请号：US11601141
申请日：2006-11-17
申请人： Oskar Zelder , Markus Pompejus , Hartwig Schröder , Burkhard Kröger , Corinna Klopprogge , Gregor Haberhauer
发明人： Oskar Zelder , Markus Pompejus , Hartwig Schröder , Burkhard Kröger , Corinna Klopprogge , Gregor Haberhauer
CPC分类号： C07K14/34 , C12N9/00 , C12N9/0006 , C12P13/08
摘要： The invention relates to novel nucleic acid molecules, to the use thereof for constructing genetically improved microorganisms and to methods for preparing fine chemicals, in particular amino acids, with the aid of said genetically improved microorganisms.
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公开(公告)号：US07355030B2
公开(公告)日：2008-04-08
申请号：US11594622
申请日：2006-11-08
申请人： Oskar Zelder , Markus Pompejus , Hartwig Schröder , Burkhard Kröger , Corinna Klopprogge , Gregor Haberhauer
发明人： Oskar Zelder , Markus Pompejus , Hartwig Schröder , Burkhard Kröger , Corinna Klopprogge , Gregor Haberhauer
CPC分类号： C07K14/34 , C12N9/00 , C12N9/0006 , C12P13/08
摘要： The invention relates to novel nucleic acid molecules, to the use thereof for constructing genetically improved microorganisms and to methods for preparing fine chemicals, in particular amino acids, with the aid of said genetically improved microorganisms.
摘要翻译： 本发明涉及新颖的核酸分子，其用于构建遗传改良的微生物的用途，以及借助所述遗传改良的微生物制备精细化学品，特别是氨基酸的方法。
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