公开(公告)号：US20080078930A1

公开(公告)日：2008-04-03

申请号：US11979219

申请日：2007-10-31

Applicant: Takashi Baba ,  Hiroyuki Satake ,  Izumi Waki

Inventor： Takashi Baba ,  Hiroyuki Satake ,  Izumi Waki

IPC: H01J49/04

CPC classification number: H01J49/4225 ,  H01J49/005 ,  H01J49/0054

Abstract: An electron capture dissociation device to implement a combination of electron capture dissociation and collision dissociation and a mass spectrometer with the use thereof are provided. This device includes a linear ion trap provided with linear multipole electrodes applied with a radio frequency electric field and wall electrodes that are arranged on both ends in the axis direction of the linear multipole electrodes, have holes on the central axis thereof, and generate a wall electric field by being applied with a direct-current voltage, a cylindrical magnetic field-generating unit that generates a magnetic field parallel to the central axis of the linear multipole electrodes and surrounds the linear ion trap, and an electron source arranged opposite to the linear multipole electrodes with sandwiching one of the wall electrodes. The electron generation site of the electron source is placed in the inside of the magnetic field generated by the magnetic field-generating unit.

Abstract translation: 提供了一种实现电子俘获解离和碰撞解离的组合的电子俘获解离装置和使用该质谱仪的电子俘获解离装置。 该装置包括线性离子阱，其设置有施加有射频电场的线性多极电极和布置在线性多极电极的轴向两端的壁电极，在其中心轴上具有孔，并产生壁 通过施加直流电压的电场，产生平行于线性多极电极的中心轴并且包围线性离子阱的磁场的圆柱形磁场产生单元，以及与线性相反的电子源 夹着一个壁电极的多极电极。 电子源的电子产生位置位于由磁场产生单元产生的磁场的内部。

公开(公告)号：US07329862B2

公开(公告)日：2008-02-12

申请号：US11495534

申请日：2006-07-31

Applicant: Yuichiro Hashimoto ,  Takashi Baba ,  Hideki Hasegawa ,  Izumi Waki

Inventor： Yuichiro Hashimoto ,  Takashi Baba ,  Hideki Hasegawa ,  Izumi Waki

IPC: H01J49/00

CPC classification number: H01J49/4225 ,  H01J49/004 ,  H01J49/401

Abstract: A mass spectrometer capable of analyzing a wide mass range with high sensitivity and high mass accuracy. A mass spectrometer has an ionization source generating ions; an ion transfer optics transferring the ions; a first linear trap accumulating the ions and ejecting the ions in the specific mass range; a second linear trap having an end electrode disposed at the exit end ejecting the ions to change a DC potential gradient relative to a DC potential of the end electrode and trapping the ions ejected from the first linear trap to repeatedly eject them in pulse form; a time-of-flight mass spectrometer accelerating the ions ejected from the second linear trap in the orthogonal direction to detect them; and a controller changing the time duration of the ions in which the ions are ejected from the second linear trap or delay time from the completion of ejection to application of an accelerating voltage of the time-of-flight mass spectrometer according to the mass range of the ions ejected from the first linear trap to the second linear trap.

Abstract translation: 能够以高灵敏度和高质量精度分析宽质量范围的质谱仪。 质谱仪具有产生离子的电离源; 离子转移光学器件转移离子; 积聚离子并在特定质量范围内喷射离子的第一线性阱; 第二线性阱，其具有设置在出射端处的终端电极，其排出离子，以相对于端电极的DC电位改变DC电位梯度，并且捕获从第一线性阱捕获的离子重复地以脉冲形式喷射; 飞行时间质谱仪在正交方向加速从第二线性阱捕获的离子以检测它们; 以及控制器，其将离子从第二线性阱捕获的离子或从完成喷射的延迟时间的持续时间改变为根据飞行时间质谱仪的加速电压的质量范围 离子从第一线性捕集器喷射到第二线性阱。

公开(公告)号：US20070069124A1

公开(公告)日：2007-03-29

申请号：US11605437

申请日：2006-11-29

Applicant: Takashi Baba ,  Yuichiro Hashimoto

Inventor： Takashi Baba ,  Yuichiro Hashimoto

IPC: H01J49/00

CPC classification number: H01J49/4225 ,  H01J49/0054 ,  H01J49/422

Abstract: The present invention provides a mass spectrometry capable of high-efficiency and high-throughput ECD. An electron source and a two-dimensional combined ion trap in which a magnetic field along and generally parallel to a central axis is applied are used, thereby to achieve the foregoing object. First, precursor ions are trapped. By adopting the two-dimensional combined ion trap, it is possible to obtain a high ion trapping efficiency upon being injected and trapping. Subsequently, electrons are made incident thereon in such a manner as to be wound along the central axis to which no radio frequency is applied by using a magnetic field. For this reason, it is possible to allow energy-controlled electrons to reach the precursor ions. It is possible to implement a mass spectrometer capable of avoiding heating due to a radio frequency electric field, and effecting high-throughput/high-efficiency ECD.

公开(公告)号：US20060012262A1

公开(公告)日：2006-01-19

申请号：US11181282

申请日：2005-07-13

Applicant: Takashi Baba ,  Manabu Okamura ,  Sachio Nakayama

Inventor： Takashi Baba ,  Manabu Okamura ,  Sachio Nakayama

IPC: H02K1/04 ,  H02K15/12 ,  H02K1/06 ,  H02K15/00

CPC classification number: H02K1/185 ,  H02K5/08 ,  Y10T29/49009

Abstract: The electric power steering apparatus includes a brushless motor as an electric motor. The motor has a rotor and a stator 34. The stator 34 includes: a back core BY; a plurality of teeth TS disposed along the circumference of the back core protruding from the back core BY toward its radial center and forming slots SL therebetween; and an exciting coil 38 wound around each of the teeth TS. Each of the slots SL is filled with a resin material. The back core BY is partially press-fitted into a yoke 21 so that the outer surface of the back core BY comes partially into contact with the inner surface of the yoke 21 along their circumferences.

Abstract translation: 电动助力转向装置包括作为电动机的无刷电动机。 电动机具有转子和定子34.定子34包括：背芯BY; 沿着背芯的圆周设置的多个齿TS，其从后芯BY向其径向中心突出并在其间形成狭槽SL; 以及缠绕在每个齿TS上的励磁线圈38。 每个槽SL填充有树脂材料。 背芯BY被部分地压配合到轭21中，使得后芯BY的外表面沿其圆周部分地与轭21的内表面接触。

公开(公告)号：US06967323B2

公开(公告)日：2005-11-22

申请号：US10868933

申请日：2004-06-17

Applicant: Yuichiro Hashimoto ,  Takashi Baba ,  Hideki Hasegawa ,  Izumi Waki

Inventor： Yuichiro Hashimoto ,  Takashi Baba ,  Hideki Hasegawa ,  Izumi Waki

IPC: G01N27/62 ,  G01N27/64 ,  H01J49/00 ,  H01J49/40 ,  H01J49/42

CPC classification number: H01J49/063 ,  H01J49/004 ,  H01J49/0481

Abstract: An ion mass spectrometer comprising an ionization source for generating ions, a linear trap region for accumulation and dissociation of ions, and a time-of-flight mass spectrometer for mass spectroscopy of ions based on the flying time, and having a collision damping region introduced with a buffer gas for reducing the kinetic energy of ions ejected from the linear trap region and converting the ion packet into continuous beam and provided with plural electrodes for generating multipole electric fields in the inside between the linear trap region and the time-of-flight mass spectrometer, and having an ion transmission control mechanism for allowing or inhibiting incidence of ion from the linear trap region to the collision damping region between the linear trap region and the collision damping region.

Abstract translation: 一种离子质谱仪，包括用于产生离子的电离源，用于离子的聚集和离解的线性捕获区域，以及用于基于飞行时间的离子质谱的飞行时间质谱仪，并且具有引入的碰撞阻尼区域 使用缓冲气体，用于降低从线性捕获区域排出的离子的动能，并将离子包转换为连续光束，并设置有多个电极，用于在线性捕获区域和飞行时间之间的内部产生多极电场 并且具有用于允许或抑制从线性捕获区域到线性捕获区域和碰撞阻尼区域之间的碰撞阻尼区域的入射的离子传输控制机构。

公开(公告)号：US06566651B2

公开(公告)日：2003-05-20

申请号：US10215014

申请日：2002-08-12

Applicant: Takashi Baba ,  Izumi Waki ,  Dongbing Wang

Inventor： Takashi Baba ,  Izumi Waki ,  Dongbing Wang

IPC: H01J4942

CPC classification number: G01N21/6404 ,  H01J49/42

Abstract: A laser-cooled fluorescence mass spectrometry apparatus includes an ion trap for trapping sample ions, laser-cooled ions, and probe ions therein; a first irradiating device for irradiating the sample ions, the laser-cooled ions, and the probe ions in the ion trap with a first laser beam for cooling the ions; a second irradiating device for irradiating the sample ions, the laser-cooled ions, and the probe ions in the ion trap with a second laser beam for detecting temperature changes in the ions; a detecting device for detecting the temperature changes in the ions; a first ion source for the sample ions; a second ion source for the laser-cooled ions; and a third ion source for the probe ions. The probe ions may be different ions than the laser-cooled ions, or the probe ions may be the same ions as the laser-cooled ions.

Abstract translation: 激光冷却荧光质谱仪包括用于捕获样品离子，激光冷却离子和探针离子的离子阱; 第一照射装置，用于用用于冷却离子的第一激光束照射离子阱中的样品离子，激光冷却离子和探针离子; 第二照射装置，用于用用于检测离子温度变化的第二激光束照射离子阱中的样品离子，激光冷却离子和探针离子; 用于检测离子温度变化的检测装置; 用于样品离子的第一离子源; 用于激光冷却离子的第二离子源; 和用于探针离子的第三离子源。 探针离子可能是与激光冷却离子不同的离子，或探针离子可能与激光冷却离子相同的离子。

公开(公告)号：US06366866B1

公开(公告)日：2002-04-02

申请号：US09237235

申请日：1999-01-26

Applicant: Makoto Kanagawa ,  Shinsuke Moriai ,  Takashi Baba ,  Hiroshi Horii

Inventor： Makoto Kanagawa ,  Shinsuke Moriai ,  Takashi Baba ,  Hiroshi Horii

IPC: G01C1738

CPC classification number: G06F3/045 ,  G06F3/0418

Abstract: In a coordinates detecting apparatus including a tablet for detecting X and Y coordinates and a correcting circuit for correcting the X and Y coordinates detected from the tablet, a parameter used for correcting the X coordinate and a parameter used for correcting the Y coordinate are adjustable independent from each other. More specifically, time constant of a CR filter circuit for the X coordinate and time constant of the CR filter circuit for the Y coordinate can be adjusted independent from each other. Further, numbers of A/D conversion, threshold values, number of samples and so on for the X and Y coordinates can be set independent from each other. As a result, in the coordinates detecting apparatus, noises in X and Y coordinates can be optimally removed, allowing detection of X and Y coordinates with high accuracy.

Abstract translation: 在包括用于检测X和Y坐标的图形输入板的坐标检测装置和用于校正从图形输入板检测到的X和Y坐标的校正电路中，用于校正X坐标的参数和用于校正Y坐标的参数是独立的 从彼此。 更具体地，可以独立地调整用于X坐标的CR滤波器电路的时间常数和用于Y坐标的CR滤波器电路的时间常数。 此外，X和Y坐标的A / D转换，阈值，采样数等的数量可以彼此独立地设置。 结果，在坐标检测装置中，可以最佳地消除X和Y坐标中的噪声，从而能够高精度地检测X和Y坐标。

公开(公告)号：US6075244A

公开(公告)日：2000-06-13

申请号：US983212

申请日：1998-01-05

Applicant: Takashi Baba ,  Izumi Waki

Inventor： Takashi Baba ,  Izumi Waki

IPC: H01J49/42 ,  B01D59/44 ,  H01J49/00

CPC classification number: H01J49/423 ,  H01J49/4215

Abstract: A method of performing a high sensitivity mass analysis is described wherein a plurality of linear quadrupole radio frequency electrodes are aligned, and operated as a mass filter or an ion trap mass analyzer. A background ion removal filter having a linear quadrupole electrode structure may also be connected in cascade to this mass analyzer if necessary. The background ion removal filter powerfully removes background ions so as to improve analytical sensitivity. This mass spectrometer also makes it possible to prevent losses of minute amounts of sample ions in the ion trap, prevent destruction of minute amounts of ions and reduce contamination of the ion trap electrodes.

Abstract translation: PCT No.PCT / JP95 / 01322 Sec。 371日期：1998年1月5日 102（e）1998年1月5日PCT PCT 1995年7月3日PCT公布。 公开号WO97 / 02591 日期1997年1月23日描述了一种进行高灵敏度质量分析的方法，其中多个线性四极杆射频电极对准，并作为质量过滤器或离子阱质量分析仪进行操作。 如果需要，具有线性四极电极结构的背景离子去除过滤器也可以与该质量分析器级联连接。 背景离子去除过滤器有力地去除背景离子，以提高分析灵敏度。 该质谱仪还能够防止离子阱中的微量离子的损失，防止微量离子的破坏，减少离子阱电极的污染。

公开(公告)号：US5783824A

公开(公告)日：1998-07-21

申请号：US886359

申请日：1997-07-01

Applicant: Takashi Baba ,  Izumi Waki

Inventor： Takashi Baba ,  Izumi Waki

IPC: H01J49/42

CPC classification number: H01J49/4225 ,  H01J49/423

Abstract: A mass spectrometry apparatus having a constitution for attaining analysis with high sensitivity and high resolving power comprising a linear radio-frequency quadrupole ion trap and means for avoiding degradation of analysis performance due to field disturbance caused by an end electrode thereof, where said purpose is achieved by means for forming a harmonic potential in the central axis thereof in whose potential ions are resonantly oscillated to be ejected outside of the ion trap for detection along the axis, or by means to eliminate undesirably- degraded signals originating near the ion trap portions that are disturbed by the end electrodes.

Abstract translation: 一种质谱装置，具有用于实现具有高灵敏度和高分辨能力的分析的结构，其包括线性射频四极离子阱和用于避免由于其端电极引起的场干扰导致的分析性能劣化的装置，其中实现了目的 通过在其中心轴上形成谐波电位的装置，其中电位离子被共振振荡以被排出离子阱外部，以便沿轴线检测，或者通过消除源自离子阱部分附近的不期望的劣化信号， 被末端电极扰乱。

公开(公告)号：US5055665A

公开(公告)日：1991-10-08

申请号：US497075

申请日：1990-03-21

Applicant: Takashi Baba ,  Yukichi Niwa ,  Minoru Yoshii ,  Takako Watanabe

Inventor： Takashi Baba ,  Yukichi Niwa ,  Minoru Yoshii ,  Takako Watanabe

IPC: G02B7/36 ,  H04N5/232

CPC classification number: G02B7/36 ,  H04N5/23212

Abstract: In an automatic focusing apparatus, a focus detecting device having detecting means for detecting the width of the edge part of the image of an object to be photographed and discriminating means for discriminating a focused state on the basis of the size of the detected width is arranged to determine by the discriminating means the apparatus to be out of focus when the width of the edge part of the object image is wide and to be in focus when the width of the edge part is narrow, so that the focus detecting device can operate without being affected by difference in the kind and the contrast of the object to be photographed.

Abstract translation: 在自动对焦装置中，具有检测装置，用于检测被拍摄对象的图像的边缘部分的宽度的检测装置和用于基于检测到的宽度的大小来鉴别聚焦状态的鉴别装置 通过鉴别装置确定当物体图像的边缘部分的宽度较宽时设备不对焦并且当边缘部分的宽度窄时聚焦，使得焦点检测装置可以在没有 受到被拍摄物体的种类和对比度的差异的影响。