Abstract:
A series of devices that allow for embedding of an image as a background while also affording the user the ability to write and print on the surface, with erasable capabilities, thus providing a multifunctional product for use in numerous industries. The devices are manufactured from predominately corrugated plastic. In one embodiment a one piece, removably attachable, cabinet system and graphic display system. In an additional embodiment, a writable board, or peg board comprising a front panel and a rear panel wherein the panels are interconnected by parallel rows, or corrugations, these panels include a writable and erasable surface. The present invention relates to assemblies of corrugated systems to better serve personal, business, and educational needs.
Abstract:
The present invention pertains to implantable or insertable medical devices which comprise a substrate and one or more therapeutic-agent-containing regions contain one or more therapeutic agents. In various aspects of the invention, one or more characteristics of such therapeutic-agent-containing regions are controlled. Further aspects of the invention relate to methods of forming such devices and to methods of using such devices.
Abstract:
An implantable or insertable medical device is provided which includes as components: (a) a substrate component comprising a depression that is at least partially filled with a therapeutic agent-containing material that comprises a first therapeutic agent, and (b) a pre-formed filter insert disposed in the depression such that it regulates transport of chemical species between the depression and the exterior of the device upon implantation or insertion of the device in vivo.
Abstract:
In one aspect, a medical device has a first configuration and a second configuration, a reservoir containing a therapeutic agent, and a barrier layer disposed over the reservoir, wherein the barrier layer comprises an inorganic material. In another aspect, a medical device has a reservoir containing a therapeutic agent, a barrier layer disposed over the reservoir, wherein the barrier layer comprises an inorganic material, and a swellable material disposed between the barrier layer and a surface of the medical device, wherein the swellable material is a material that swells upon exposure to an aqueous environment. In yet another aspect, a medical device has a multi-layered coating having alternating reservoir layers and barrier layers, and a plurality of excavated regions penetrating through at least a partial thickness of the multi-layered coating. In yet another aspect, a medical device has a polymer layer comprising a block co-polymer, wherein the polymer layer contains a therapeutic agent, and a barrier layer disposed over the polymer layer, wherein the barrier layer comprises an inorganic material, and wherein the barrier layer has a plurality of discontinuities. Methods of forming coatings on medical devices and methods of delivering therapeutic agents to body sites are also disclosed.
Abstract:
A method for holistic project management may include presenting a graphical user interface for a user to enter project information for a project. The method may also include determining a priority for the project based on an impact of the project to each of a plurality of predetermined drivers.
Abstract:
A series of devices that allow for embedding of an image as a background while also affording the user the ability to write and print on the surface, with erasable capabilities, thus providing a multifunctional product for use in numerous industries. The devices are manufactured from predominately corrugated plastic. In one embodiment, a writable board, or peg board comprising a front panel and a rear panel wherein the panels are interconnected by parallel rows, or corrugations, these panels include a writable and erasable surface. The present invention relates to novel assemblies of conventional corrugated plastic sheets to better serve personal, business, and educational needs.
Abstract:
Systems for nerve modulation and methods for making and using the same are disclosed. An example system for nerve modulation may include a first elongate element having a distal end and a proximal end and having a helical guide having a proximal end and a distal end. The system may also include a second elongate element having a distal end and a proximal end and having a nerve modulation element proximate the distal end. A sheath may be disposed about both the first and second elongate elements. Pulling proximally on the proximal end of the first elongate element may cause simultaneous radial and longitudinal displacement of the nerve modulation element.
Abstract:
Provided is a coated medical device (e.g., a stent) comprising one or more surfaces having dispersed thereon a plurality of microparticles comprising an active pharmaceutical ingredient (API) and a polymer. Specifically, the microparticles are disposed on a device surface in a microparticulate phase coating, i.e., as discrete microparticles in the absence of a continuous phase coating. The medical device effectively adheres one or more APIs to its surface, and allows controlled release of the APIs from the device surface to a desired treatment area by using a minimal amount of polymer. The medical device is suitable for insertion or implantation into a subject, preferably a human. Also provided are methods for preparing and using the coated medical device.