公开(公告)号：US20060262313A1

公开(公告)日：2006-11-23

申请号：US11460932

申请日：2006-07-28

Applicant: Dar Bahatt ,  Jerry Cahill ,  Koichi Nishikida ,  Enrico Picozza ,  Paul Saviano ,  David Tracy ,  Yongdong Wang

Inventor： Dar Bahatt ,  Jerry Cahill ,  Koichi Nishikida ,  Enrico Picozza ,  Paul Saviano ,  David Tracy ,  Yongdong Wang

IPC: G01N21/55

CPC classification number: G01N21/7703 ,  G01N21/553

Abstract: An optical resonance analysis system comprising a sensor means (60) and an illumination means (400) for generating non-monochromatic illumination. The illumination means (400) further comprises a means for generating illumination at a plurality of angles, a lens system for projecting said illumination at said plurality of angles (390) and a dispersive device (380) for dispersing said illumination at each of said plurality of angles so that there is a correlation between said plurality of angles and the wavelengths of said illumination such that a resonance condition is generated on said sensor mean (60) for all wavelengths generated by said non-monochromatic source simultaneously. The analysis system also comprises a detection means (90) for detecting the reflected or transmitted illumination. Another embodiment comprises an anamorphic imaging means (120).

Abstract translation: 一种光学共振分析系统，包括传感器装置（60）和用于产生非单色照明的照明装置（400）。 照明装置（400）还包括用于以多个角度产生照明的装置，用于以所述多个角度（390）投射所述照明的透镜系统和用于将所述照明分散在所述多个角度的分散装置（380） 的角度，使得在所述多个角度和所述照明的波长之间存在相关性，使得对于由所述非单色源同时产生的所有波长的所述传感器平均值（60）产生共振条件。 分析系统还包括用于检测反射或透射照明的检测装置（90）。 另一实施例包括变形成像装置（120）。

公开(公告)号：US20060169883A1

公开(公告)日：2006-08-03

申请号：US11261440

申请日：2005-10-28

Applicant: Yongdong Wang ,  Ming Gu

Inventor： Yongdong Wang ,  Ming Gu

IPC: B01D59/44

CPC classification number: H01J49/0036 ,  B01D59/44 ,  H01J49/0009

Abstract: A method for calibrating and analyzing data from a mass spectrometer, comprising the steps of acquiring raw profile mode data containing mass spectral responses of ions with or without isotopes; calculating theoretical isotope distributions for each of at least one calibration ion based on elemental composition; convoluting the theoretical isotope distributions with an initial peak shape function to obtain theoretical isotope profiles for each ion; constructing a peak component matrix including the theoretical isotope profiles for calibration ions as peak components; performing a regression analysis between the raw profile mode mass spectral data and the peak component matrix; and reporting the regression coefficients as the relative concentrations for each of the components. A mass spectrometry system operated in accordance with the method and a computer readable medium having program code thereon for performing the method.

Abstract translation: 一种用于校准和分析来自质谱仪的数据的方法，包括以下步骤：获取包含具有或不具有同位素的离子的质谱响应的原始轮廓模式数据; 基于元素组成计算每个至少一个校准离子的理论同位素分布; 将理论同位素分布与初始峰形函数进行卷积，以获得每个离子的理论同位素分布; 构建包括校准离子的理论同位素分布的峰分量矩阵作为峰分量; 在原始轮廓模式质谱数据和峰分量矩阵之间执行回归分析; 并将回归系数报告为每个组分的相对浓度。 根据该方法操作的质谱系统和其上具有用于执行该方法的程序代码的计算机可读介质。

公开(公告)号：US20060088444A1

公开(公告)日：2006-04-27

申请号：US11251873

申请日：2005-10-18

Applicant: Michael Gambini ,  John Voyta ,  John Atwood ,  Susan Atwood Stone ,  Bruce DeSimas ,  Edward Lakatos ,  Jeff Levi ,  Israel Metal ,  George Sabak ,  Yongdong Wang

Inventor： Michael Gambini ,  John Voyta ,  John Atwood ,  Susan Atwood Stone ,  Bruce DeSimas ,  Edward Lakatos ,  Jeff Levi ,  Israel Metal ,  George Sabak ,  Yongdong Wang

IPC: G01N21/64

CPC classification number: G01N21/763 ,  G01N21/15 ,  G01N21/274 ,  G01N21/276 ,  G01N21/31 ,  G01N21/6452 ,  G01N21/6456 ,  G01N21/6486 ,  G01N21/76 ,  G01N33/581 ,  G01N2021/6471 ,  G01N2333/90241 ,  Y10T436/115831

Abstract: In a luminescence detecting apparatus and method for analyzing luminescent samples, luminescent samples are placed in a plurality of sample wells in a tray, and the tray is placed in a visible-light impervious chamber containing a charge coupled device camera. In the chamber, light from the luminescent samples pass through a collimator, a Fresnel field lens, an infrared filter, and a camera lens, whereupon a focused image is created by the optics on the camera. The use of an infrared filter suppresses stray IR radiation resulting from plate phosphorescence (which can result in abnormally high backgrounds and/or alteration of the image received by the camera).

Abstract translation: 在用于分析发光样品的发光检测装置和方法中，将发光样品放置在托盘中的多个样品孔中，并将该托盘放置在包含电荷耦合器件相机的可见光不透过室中。 在室中，来自发光样品的光通过准直仪，菲涅尔场透镜，红外滤光镜和照相机镜头，由相机上的光学器件产生聚焦图像。 使用红外滤光器可抑制板状磷光产生的杂散红外辐射（可能导致摄像机接收的图像异常高的背景和/或变化）。

公开(公告)号：US20050086017A1

公开(公告)日：2005-04-21

申请号：US10689313

申请日：2003-10-20

Applicant: Yongdong Wang

Inventor： Yongdong Wang

IPC: C12Q1/00 ,  G01D18/00 ,  G01N3/00 ,  G01N21/00 ,  G01N21/01 ,  G01N23/00 ,  G01P21/00 ,  G01R35/00 ,  G06F20060101 ,  G06F15/00 ,  G06K9/00 ,  H01J49/00

CPC classification number: G06K9/00496 ,  H01J49/0009 ,  H01J49/0027

Abstract: There is provided a method for obtaining at least one calibration filter for a Mass Spectrometry (MS) instrument system. Measured isotope peak cluster data in a mass spectral range is obtained for a given calibration standard. Relative isotope abundances and actual mass locations of isotopes corresponding thereto are calculated for the given calibration standard. Mass spectral target peak shape functions centered within respective mass spectral ranges are specified. Convolution operations are performed between the calculated relative isotope abundances and the mass spectral target peak shape functions to form calculated isotope peak cluster data. A deconvolution operation is peformed between the measured isotope peak cluster data and the calculated isotope peak cluster data after the convolution operations to obtain the at least one calibration filter.

Abstract translation: 提供了一种用于获得用于质谱（MS）仪器系统的至少一个校准滤波器的方法。 对于给定的校准标准，获得质谱范围内的测量同位素峰聚类数据。 对于给定的校准标准，计算与之对应的同位素的相对同位素丰度和实际质量位置。 规定了在各个质谱范围内的质谱目标峰形函数。 在所计算的相对同位素丰度和质谱目标峰形状函数之间进行卷积运算，以形成计算的同位素峰集群数据。 在卷积操作之后，测量的同位素峰簇数据和计算出的同位素峰簇数据之间进行去卷积操作，以获得至少一个校准滤波器。

公开(公告)号：US06873417B2

公开(公告)日：2005-03-29

申请号：US10425799

申请日：2003-04-28

Applicant: Dar Bahatt ,  Jerry E. Cahill ,  Koichi Nishikida ,  Enrico G. Picozza ,  Paul G. Saviano ,  David H. Tracy ,  Yongdong Wang

Inventor： Dar Bahatt ,  Jerry E. Cahill ,  Koichi Nishikida ,  Enrico G. Picozza ,  Paul G. Saviano ,  David H. Tracy ,  Yongdong Wang

IPC: G01N21/27 ,  G01N21/55 ,  G01N21/47

CPC classification number: G01N21/7703 ,  G01N21/553

Abstract: An optical resonance analysis system comprising a sensor means (60) and an illumination means (400) for generating non-monochromatic illumination. The illumination means (400) further comprises a means for generating illumination at a plurality of angles, a lens system for projecting said illumination at said plurality of angles (390) and a dispersive device (380) for dispersing said illumination at each of said plurality of angles so that there is a correlation between said plurality of angles and the wavelengths of said illumination such that a resonance condition is generated on said sensor mean (60) for all wavelengths generated by said non-monochromatic source simultaneously. The analysis system also comprises a detection means (90) for detecting the reflected or transmitted illumination. Another embodiment comprises an anamorphic imaging means (120).

Abstract translation: 一种光学共振分析系统，包括传感器装置（60）和用于产生非单色照明的照明装置（400）。 照明装置（400）还包括用于以多个角度产生照明的装置，用于以所述多个角度（390）投射所述照明的透镜系统和用于将所述照明分散在所述多个角度的分散装置（380） 的角度，使得在所述多个角度和所述照明的波长之间存在相关性，使得对于由所述非单色源同时产生的所有波长的所述传感器平均值（60）产生共振条件。 分析系统还包括用于检测反射或透射照明的检测装置（90）。 另一实施例包括变形成像装置（120）。

公开(公告)号：US06865493B2

公开(公告)日：2005-03-08

申请号：US10618822

申请日：2003-07-14

Applicant: Yongdong Wang

Inventor： Yongdong Wang

IPC: G01N21/27 ,  G01N30/74 ,  G01N30/86 ,  G01N31/00 ,  G06F19/00

CPC classification number: G01N30/8689 ,  G01N30/74 ,  G01N30/8644

Abstract: A method and apparatus is provided for detecting an impurity in a sample where an index can be calculated to assess purity in the presence of n major components with signal averaging or noise-filtering automatically built-in. The method and apparatus can be applied to liquid chromatography impurity detection using UV-VIS spectrophotometry based on robust matrix algebra representing the entire spectral space generated by the sample.

Abstract translation: 提供了一种方法和装置，用于检测样品中的杂质，其中可以计算指数以在存在n个主要成分的情况下评估纯度，其中自动内置信号平均或噪声滤波。 该方法和装置可应用于基于表示由样品产生的整个光谱空间的鲁棒矩阵代数的使用UV-VIS分光光度法的液相色谱杂质检测。

公开(公告)号：US06629039B1

公开(公告)日：2003-09-30

申请号：US09561600

申请日：2000-04-27

Applicant: Yongdong Wang

Inventor： Yongdong Wang

IPC: G01N3100

CPC classification number: G01N30/8689 ,  G01N30/74 ,  G01N30/8644

Abstract: A method and apparatus is provided for detecting an impurity in a sample where an index can be calculated to assess purity in the presence of n major components with signal averaging or noise-filtering automatically built-in. The method and apparatus can be applied to liquid chromatography impurity detection using UV-VIS spectrophotometry based on robust matrix algebra representing the entire spectral space generated by the sample.

Abstract translation: 提供了一种方法和装置，用于检测样品中的杂质，其中可以计算指数以在存在n个主要成分的情况下评估纯度，其中自动内置信号平均或噪声滤波。 该方法和装置可应用于基于表示由样品产生的整个光谱空间的鲁棒矩阵代数的使用UV-VIS分光光度法的液相色谱杂质检测。

公开(公告)号：US06600563B1

公开(公告)日：2003-07-29

申请号：US09486424

申请日：2000-07-17

Applicant: Dar Bahatt ,  Jerry E. Cahill ,  Koichi Nishikida ,  Enrico G. Picozza ,  Paul G. Saviano ,  David H. Tracy ,  Yongdong Wang

Inventor： Dar Bahatt ,  Jerry E. Cahill ,  Koichi Nishikida ,  Enrico G. Picozza ,  Paul G. Saviano ,  David H. Tracy ,  Yongdong Wang

IPC: G01N2155

CPC classification number: G01N21/7703 ,  G01N21/553

Abstract: An optical resonance analysis system comprising a sensor means (60) and an illumination means (400) for generating non-monochromatic illumination. The illumination means (400) further comprises a means for generating illumination at a plurality of angles, a lens system for projecting said illumination at said plurality of angles (390) and a dispersive device (380) for dispersing said illumination at each of said plurality of angles so that there is a correlation between said plurality of angles and the wavelengths of said illumination such that a resonance condition is generated on said sensor mean (60) for all wavelengths generated by said non-monochromatic source simultaneously. The analysis system also comprises a detection means (90) for detecting the reflected or transmitted illumination. Another embodiment comprises an anamorphic imaging means (120).

Abstract translation: 一种光学共振分析系统，包括传感器装置（60）和用于产生非单色照明的照明装置（400）。 照明装置（400）还包括用于以多个角度产生照明的装置，用于以所述多个角度（390）投射所述照明的透镜系统和用于将所述照明分散在所述多个角度的分散装置（380） 的角度，使得在所述多个角度和所述照明的波长之间存在相关性，使得对于由所述非单色源同时产生的所有波长的所述传感器平均值（60）产生共振条件。 分析系统还包括用于检测反射或透射照明的检测装置（90）。 另一实施例包括变形成像装置（120）。

公开(公告)号：US5428558A

公开(公告)日：1995-06-27

申请号：US168800

申请日：1993-12-17

Applicant: Jerry E. Cahill ,  Alan M. Ganz ,  Paul Saviano ,  David Tracy ,  Yongdong Wang

Inventor： Jerry E. Cahill ,  Alan M. Ganz ,  Paul Saviano ,  David Tracy ,  Yongdong Wang

IPC: G01J3/02 ,  G01J3/28 ,  G01N21/27 ,  G01D18/00

CPC classification number: G01J3/28 ,  G01J2003/2866

Abstract: A method and apparatus are provided for correction of spectra for stray radiation in a spectrometric instrument, involving a sequence of steps as follows. Spectral patterns are obtained with the instrument initially for monochromatic radiation at a plurality of selected calibration wavelengths. By computer program, the peak profile at the calibration wavelength in each pattern is replaced with a substitute based on the remaining pattern. The resulting data are interpolated to effect values denoted "stray proportions" for the ordered wavelengths of the instrument. Spectral data at each ordered wavelength are obtained with the instrument for a sample, and multiplied in the computer program by stray proportions for corresponding wavelengths to effect further sets of values denoted "stray portions" that are identified to the ordered wavelengths. Each set is identified to one of the wavelength increments of the instrument across the spectral range. In each set, the stray portions for the ordered wavelengths are summed. The total for each wavelength increment is subtracted from the original sample data for the increment to effect spectral data corrected for stray.

Abstract translation: 提供了一种用于校正光谱仪器中杂散辐射的光谱的方法和装置，涉及如下的一系列步骤。 在多个选定的校准波长下，仪器最初用于单色辐射获得光谱图案。 通过计算机程序，每个模式中校准波长处的峰值曲线被替换为基于剩余模式的替代。 内插所得数据以对仪器的有序波长表示为“杂散比”的值。 用样品的仪器获得每个有序波长的光谱数据，并在计算机程序中乘以相应波长的杂散比例，以实现被标识为有序波长的标记为“杂散部分”的另外一组值。 每个组被识别为跨越光谱范围的仪器的波长增量之一。 在每组中，将有序波长的杂散部分相加。 从原始采样数据中减去每个波长增量的总和，以增加修正为杂散的光谱数据。

公开(公告)号：US20130112725A1

公开(公告)日：2013-05-09

申请号：US13490005

申请日：2012-06-06

Applicant: Tao Luo ,  Jinghong Yang ,  Yongdong Wang ,  Cuihong Wu ,  Zhenxiong Huang ,  Qingqiang Lu ,  Ying Chen ,  Xiaohong Luo ,  Guoxun Chen ,  Yun Luo ,  Furong Bai ,  Songlin Wang ,  Yanhong Wang ,  Xiaojin Peng

Inventor： Tao Luo ,  Jinghong Yang ,  Yongdong Wang ,  Cuihong Wu ,  Zhenxiong Huang ,  Qingqiang Lu ,  Ying Chen ,  Xiaohong Luo ,  Guoxun Chen ,  Yun Luo ,  Furong Bai ,  Songlin Wang ,  Yanhong Wang ,  Xiaojin Peng

IPC: B60R7/00

CPC classification number: G07G1/0045 ,  G07F17/0042 ,  G07G1/009

Abstract: The present disclosure discloses a vehicle-mounted library workstation, comprising a shell, on which a books and disks identifying module and a reader card identifying module are arranged; wherein the books and disks identifying module comprises a book reading antenna and a book reader for driving the book reading antenna, decoding and transferring data scanned by the book reading antenna; the book reader and reader card reading device are RFID tags readers; the vehicle-mounted library workstation being connected to a computer while working, wherein the computer controls the reader card identifying module to collect information of the reader card, controls the books and disks identifying module to collect information of the books and disks, and processes the information of the reader card and information of the books or disks to finish operations of borrowing and returning books.

Abstract translation: 本公开公开了一种车载图书馆工作站，包括壳体，其上布置有书籍和盘识别模块和读卡器识别模块; 其中书籍和磁盘识别模块包括书阅读天线和用于驱动书阅读天线的书阅读器，解码和传送由书阅读天线扫描的数据; 读卡器和读卡器读卡器是RFID标签阅读器; 车载图书馆工作站在工作时连接到计算机，其中计算机控制读卡器识别模块以收集读卡器的信息，控制书籍和磁盘识别模块以收集书籍和磁盘的信息，并处理 读卡器的信息和书籍或磁盘的信息，以完成借书和借书的操作。