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公开(公告)号:US5455231A
公开(公告)日:1995-10-03
申请号:US980370
申请日:1992-11-23
IPC分类号: A61F2/00 , A61L27/24 , A61L27/36 , A61L27/42 , A61L27/46 , C07K14/78 , C08L89/06 , A61F2/28 , A61K38/39
CPC分类号: C08L89/06 , A61L27/46 , C07K14/78 , A61F2310/00365 , Y10S128/08 , Y10S514/801
摘要: Mineralized collagen is prepared by forming calcium phosphate mineral under mild agitation in situ in the presence of dispersed collagen fibrils. A stable composition is obtained with desirable physical characteristics mimicking the characteristics of bone.
摘要翻译: 在分散的胶原纤维存在下,通过在温和搅拌下原位形成磷酸钙矿物来制备矿化胶原蛋白。 获得具有模拟骨特征的理想物理特性的稳定组合物。
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公开(公告)号:US5129905A
公开(公告)日:1992-07-14
申请号:US393579
申请日:1989-08-14
申请人: Brent R. Constantz
发明人: Brent R. Constantz
IPC分类号: A61L27/00 , A61F2/00 , A61K6/033 , A61L24/02 , A61L27/12 , A61L27/46 , C01B25/32 , C01B25/455 , C04B35/447
CPC分类号: A61K6/033 , A61K6/0023 , A61K6/0038 , A61L24/02 , A61L27/12 , A61L27/46 , C01B25/32 , C01B25/322 , C01B25/327 , C01B25/455 , A61F2310/00293
摘要: Calcium phosphate minerals are formed by using phosphoric acid source substantially free of uncombined water in conjunction with a calcium source, normally as any combination of carbonate, phosphate and hydroxide, and, as required, any additional base to neutralize the phosphoric acid. Protein may be optionally added. The resulting product is readily formed and then sets to a hard, stable, workable shaped object.
摘要翻译: 磷酸钙矿物是通过使用基本上不含未结合水的磷酸源与钙源形成的,钙源通常以碳酸盐,磷酸盐和氢氧化物的任何组合以及根据需要的任何额外的碱来中和磷酸。 蛋白质可以任选加入。 所得到的产品容易地形成,然后设置成硬的,稳定的可加工的成形物体。
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公开(公告)号:US4880610A
公开(公告)日:1989-11-14
申请号:US183770
申请日:1988-04-20
申请人: Brent R. Constantz
发明人: Brent R. Constantz
IPC分类号: A61K47/02 , A61F2/00 , A61F2/02 , A61F2/28 , A61K6/033 , A61L24/02 , A61L27/00 , A61L27/12 , A61L27/46 , A61L27/50 , A61L27/58 , C01B25/16 , C01B25/32 , C01B25/455
CPC分类号: A61K6/033 , A61K6/0023 , A61K6/0038 , A61K6/0085 , A61K6/0643 , A61K6/0668 , A61K6/0675 , A61L24/02 , A61L27/12 , A61L27/46 , A61L27/50 , A61L27/58 , C01B25/16 , C01B25/32 , C01B25/322 , C01B25/327 , C01B25/455 , A61F2002/2817 , A61F2002/30062 , A61F2210/0004 , A61F2310/00293 , Y10S623/901
摘要: Calcium phosphate minerals are formed by using highly concentrated phosphoric acid in conjunction with a calcium source, normaly as carbonate or a combination of carbonate and hydroxide, optimally in conjunction with calcium phosphate crystals and additional base to neutralize the phosphoric acid. Protein may be optionally added. The resulting product is readily formed and then sets to a hard, stable, workable shaped object.
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公开(公告)号:US09707024B2
公开(公告)日:2017-07-18
申请号:US13347524
申请日:2012-01-10
CPC分类号: A61B17/8822 , A61F2002/4683 , A61K33/42
摘要: Methods of employing bone defect filling, e.g., orthopedic cements, in conjunction with hard tissue securing devices, e.g., screws, plates or rods, are provided. A feature of the subject methods is that the cement is introduced to a target bone site through a passageway of the securing device while a vibratory force is applied to the securing device. Also provided are systems and kits that find use in practicing the subject methods. The subject methods, devices and systems find use in a variety of different applications.
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公开(公告)号:US20120253351A1
公开(公告)日:2012-10-04
申请号:US13434669
申请日:2012-03-29
IPC分类号: A61B17/56
CPC分类号: A61B17/8822 , A61F2002/4602 , A61F2002/4683 , A61K33/42
摘要: Methods of employing bone defect filling, e.g., orthopedic cements, such as calcium phosphate cements and the like, are provided. A feature of the subject methods is that vibration is employed in conjunction with the use of the cement, e.g., in preparation of the cement, in preparation of the target site, in delivery of the cement to the target site, and/or following delivery of the cement to the target site. Also provided are devices, systems and kits that find use in practicing the subject methods. The subject methods, devices and systems find use in a variety of different applications.
摘要翻译: 提供使用骨缺损填充的方法,例如矫形水泥,例如磷酸钙水泥等。 主题方法的一个特征是,与水泥的使用结合使用振动,例如在准备水泥时,在制备目标地点时,将水泥输送到目标地点和/或在运送之后 的水泥到目标地点。 还提供了用于实践主题方法的设备,系统和工具包。 主题方法,设备和系统可用于各种不同的应用。
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公开(公告)号:US08167889B2
公开(公告)日:2012-05-01
申请号:US11771603
申请日:2007-06-29
CPC分类号: A61B17/8822 , A61F2002/4602 , A61F2002/4683 , A61K33/42
摘要: Methods of employing bone defect filling, e.g., orthopedic cements, such as calcium phosphate cements and the like, are provided. A feature of the subject methods is that vibration is employed in conjunction with the use of the cement, e.g., in preparation of the cement, in preparation of the target site, in delivery of the cement to the target site, and/or following delivery of the cement to the target site. Also provided are devices, systems and kits that find use in practicing the subject methods. The subject methods, devices and systems find use in a variety of different applications.
摘要翻译: 提供使用骨缺损填充的方法,例如矫形水泥,例如磷酸钙水泥等。 主题方法的一个特征是,与水泥的使用结合使用振动,例如在准备水泥时,在制备目标地点时,将水泥输送到目标地点和/或在运送之后 的水泥到目标地点。 还提供了用于实践主题方法的设备,系统和工具包。 主题方法,设备和系统可用于各种不同的应用。
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公开(公告)号:US20110290156A1
公开(公告)日:2011-12-01
申请号:US13191209
申请日:2011-07-26
CPC分类号: C04B28/04 , B01D2257/504 , C04B22/10 , C04B28/02 , C04B2103/0086 , C04B2111/00017 , C04B22/106
摘要: CO2-sequestering formed building materials are provided. The building materials of the invention include a composition comprising a carbonate/bicarbonate component. Additional aspects of the invention include methods of making and using the CO2-sequestering formed building material.
摘要翻译: 提供二氧化碳螯合形成的建筑材料。 本发明的建筑材料包括包含碳酸盐/碳酸氢盐组分的组合物。 本发明的另外的方面包括制备和使用形成二氧化碳螯合形成的建筑材料的方法。
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公开(公告)号:US07771684B2
公开(公告)日:2010-08-10
申请号:US12571398
申请日:2009-09-30
IPC分类号: C01B31/24
CPC分类号: C04B28/04 , B01D2257/504 , C04B22/10 , C04B28/02 , C04B2103/0086 , C04B2111/00017 , C04B22/106
摘要: CO2-sequestering formed building materials are provided. The building materials of the invention include a composition comprising a carbonate/bicarbonate component. Additional aspects of the invention include methods of making and using the CO2-sequestering formed building material.
摘要翻译: 提供二氧化碳螯合形成的建筑材料。 本发明的建筑材料包括包含碳酸盐/碳酸氢盐组分的组合物。 本发明的另外的方面包括制备和使用形成二氧化碳螯合形成的建筑材料的方法。
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公开(公告)号:US07735274B2
公开(公告)日:2010-06-15
申请号:US12126776
申请日:2008-05-23
申请人: Brent R. Constantz , Cecily Ryan , Laurence Clodic
发明人: Brent R. Constantz , Cecily Ryan , Laurence Clodic
CPC分类号: C04B28/04 , C04B14/26 , Y02W10/33 , Y02W10/37 , Y10T428/2982
摘要: Hydraulic cement compositions that include a carbonate compound composition, e.g., a salt-water derived carbonate compound composition containing crystalline and/or amorphous carbonate compounds, are provided. Also provided are methods of making and using the hydraulic cements, as well as settable compositions, such as concretes and mortars, prepared therefrom. The cements and compositions produced therefrom find use in a variety of applications, including use in a variety of building materials and building applications.
摘要翻译: 提供了包含碳酸盐化合物组合物的液压水泥组合物,例如含有结晶和/或无定形碳酸酯化合物的盐水衍生的碳酸盐化合物组合物。 还提供了制备和使用水硬性水泥的方法,以及由其制备的可固化组合物,例如混凝土和砂浆。 由此产生的水泥和组合物可用于各种应用,包括用于各种建筑材料和建筑应用中。
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公开(公告)号:US07658940B2
公开(公告)日:2010-02-09
申请号:US11694807
申请日:2007-03-30
申请人: Brent R. Constantz
发明人: Brent R. Constantz
CPC分类号: A61L27/365 , A61L27/12 , A61L27/3608 , A61L27/425
摘要: Aspects of the invention include methods for producing flowable compositions, e.g. pastes, that set into calcium phosphate containing products, where the products include autologous bone. Aspects of the invention further include compositions produced by the methods, as well as kits for preparing the same. The subject methods and compositions produced thereby find use in a variety of applications, including hard tissue repair applications.
摘要翻译: 本发明的方面包括用于生产可流动组合物的方法,例如。 糊剂,其中含有磷酸钙的产品,其中产品包括自体骨。 本发明的方面还包括通过该方法制备的组合物,以及制备该组合物的试剂盒。 由此产生的主题方法和组合物可用于各种应用,包括硬组织修复应用。
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