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    Light color and intensity modulation system
    41.
    发明授权
    Light color and intensity modulation system 失效
    浅色调强度调制系统

    公开(公告)号：US5070399A

    公开(公告)日：1991-12-03

    申请号：US631489

    申请日：1990-12-21

    申请人： Alain Martel

    发明人： Alain Martel

    IPC分类号： G09G1/28 ,  H04N9/31

    CPC分类号： H04N9/31 ,  G09G1/28

    摘要： A color and intensity modulation system has an output to be connected to a color light projector and an input to receive a hue control signal and an intensity control signal including at least one modulation frequency component F. The system comprises a color scaling device, receiving in use the hue signal, the color scaling device producing a plurality of color component signals, the plurality of color component signals being supplied as the output to the color light projector, and an intensity control device, receiving in use the intensity control signal, the intensity control device comprising a low frequency oscillator whose output is an intensity modulation signal for varying an intensity of the plurality of color component signals between a preset minimum and a preset maximum value, the oscillator having a frequency responsive to the at least one modulation frequency component F of the intensity control signal, the plurality of color component signals to control in use the projector. The projected light can have a relaxing visual effect.

    摘要翻译： 颜色和强度调制系统具有连接到彩色投影仪的输出端和用于接收色调控制信号的输入端和包括至少一个调制频率分量F的强度控制信号。该系统包括一个颜色缩放装置， 使用色调信号，所述颜色缩放装置产生多个颜色分量信号，所述多个颜色分量信号作为输出被提供给彩色投影仪;以及强度控制装置，在使用中接收强度控制信号，强度 控制装置包括低频振荡器，其输出是用于在预设最小值和预置最大值之间改变所述多个颜色分量信号的强度的强度调制信号，所述振荡器具有响应于所述至少一个调制频率分量F 的强度控制信号，多个颜色分量信号在使用中控制项目 呃 投影光可以具有轻松的视觉效果。

    Sulfated .beta.-glycolipid derivatives as cell adhesion inhibitors
    47.
    发明授权
    Sulfated .beta.-glycolipid derivatives as cell adhesion inhibitors 失效
    硫酸化β-糖脂衍生物作为细胞粘附抑制剂

    公开(公告)号：US5565433A

    公开(公告)日：1996-10-15

    申请号：US600558

    申请日：1996-02-12

    申请人： Jacques Banville ,  Alain Martel ,  Alejandro A. Aruffo

    发明人： Jacques Banville ,  Alain Martel ,  Alejandro A. Aruffo

    IPC分类号： C07H15/04 ,  A61K31/70 ,  A61K31/7028 ,  A61P29/00 ,  A61P43/00 ,  C07H15/10 ,  C07H11/00

    CPC分类号： C07H15/10

    摘要： There is provided novel sulfated p-glycolipid compounds of the formula ##STR1## wherein R is an acyl residue of a fatty acid;R.sup.1 is --(CH.dbd.CH).sub.m --(CH.sub.2).sub.n --CH.sub.3 ;R.sup.2, R.sup.3, R.sup.4 and R.sup.6 each are independently --SO.sub.3 H, hydrogen, unsubstituted or substituted alkanoyl, arylalkyl or arylcarbonyl wherein said substituent is selected from the group consisting of halogen, C.sub.1-4 alkyl, trifluoromethyl, hydroxy and C.sub.1-4 alkoxy; or R.sub.4 and R.sub.6, taken together are isopropylidene; provided at least two of R.sup.2, R.sup.3, R.sup.4 and R.sup.6 are --SO.sub.3 H;R.sup.5 is hydrogen, unsubstituted or substituted alkanoyl, arylalkyl or arylcarbonyl wherein said substituent is selected from the group consisting of halogen, C.sub.1-4 alkyl, trifluoromethyl, hydroxy and C.sub.1-4 alkoxy;m is an integer of 0 or 1;n is an integer of from 5 to 14, inclusive;or a non-toxic pharmaceutically acceptable salt, solvate or hydrate thereof which are inhibitors of selectin-mediated cellular adhesion and are useful in the treatment or prevention of inflammatory diseases and other pathological conditions in mammals.

    摘要翻译： 提供了式Ⅰ的新型硫酸化p-糖脂化合物，其中R是脂肪酸的酰基残基; R 1是 - （CH = CH）m - （CH 2）n -CH 3; R 2，R 3，R 4和R 6各自独立地为-SO 3 H，氢，未取代或取代的烷酰基，芳烷基或芳基羰基，其中所述取代基选自卤素，C 1-4烷基，三氟甲基，羟基和C 1-4烷氧基; 或R4和R6一起为异丙叉; 提供R 2，R 3，R 4和R 6中的至少两个是-SO 3 H; R5是氢，未取代或取代的烷酰基，芳基烷基或芳基羰基，其中所述取代基选自卤素，C 1-4烷基，三氟甲基，羟基和C 1-4烷氧基; m为0或1的整数; n为5〜14的整数，包括端值; 或其选择素介导的细胞粘附的抑制剂的无毒的药学上可接受的盐，溶剂化物或水合物，并且可用于治疗或预防哺乳动物的炎性疾病和其它病理状况。