公开(公告)号：US08592625B2

公开(公告)日：2013-11-26

申请号：US12811418

申请日：2008-01-02

申请人： Jiankang Xu ,  Da Zhang ,  Meiqi Ye ,  Jie Chen ,  Yongbing Guo ,  Yongjiang Hu

发明人： Jiankang Xu ,  Da Zhang ,  Meiqi Ye ,  Jie Chen ,  Yongbing Guo ,  Yongjiang Hu

IPC分类号： C07C227/36

CPC分类号： C07C227/34 ,  C07C229/08

摘要： The present invention relates to a process for resolving S-3-(Aminomethyl)-5-methylhexanoic acid, which adopts benzoyl-L-glutamic acid, 4-methyl benzoyl-L-glutamic acid, benzene sulfonyl-L-glutamic acid or 4-methyl benzene sulfonyl-L-glutamic acid as a resolution agent to make a first resolution to racemic 3-aminomethyl-5-methylhexanoic acid, and adopts the resolution agent same to that of the first resolution to make a second resolution to the first resolution product to obtain the second resolution product, thus the resolution salt product is obtained, and further hydrolyzed by an acid, the resolution agent is extracted to be separated, the pH is adjusted to be neutral, the product S-3-(Aminomethyl)-5-methylhexanoic acid, i.e. the pregabalin, is then precipitated by distillation, therefore the present invention has the characteristics of polluting the environment slightly, high efficiency and stability, simpleness and practicality, producing product with high purity and a low production cost, and is suitable for large-scale production.

摘要翻译： 本发明涉及一种分离S-3-（氨基甲基）-5-甲基己酸的方法，该方法采用苯甲酰基-L-谷氨酸，4-甲基苯甲酰基-L-谷氨酸，苯磺酰基-L-谷氨酸或4 甲基苯磺酰基-L-谷氨酸作为拆分剂，首先拆分为外消旋的3-氨基甲基-5-甲基己酸，并采用与第一分辨率相同的分解剂，以第一分辨率作第二分辨率 得到第二分解产物，得到分解盐产物，并进一步用酸水解，提取分离剂分离，将pH调节为中性，产物S-3-（氨基甲基） - 5-甲基己酸，即普瑞巴林，然后通过蒸馏沉淀，因此本发明具有污染环境的特点，效率高，稳定性，简便性和实用性，生产高纯度，低产品的产品 离子成本，适合大规模生产。

公开(公告)号：US20130241683A1

公开(公告)日：2013-09-19

申请号：US13419272

申请日：2012-03-13

申请人： Hao-Yi Tsai ,  Hsien-Wei Chen ,  Hung-Yi Kuo ,  Jie Chen ,  Ying-Ju Chen ,  Tsung-Yuan Yu

发明人： Hao-Yi Tsai ,  Hsien-Wei Chen ,  Hung-Yi Kuo ,  Jie Chen ,  Ying-Ju Chen ,  Tsung-Yuan Yu

IPC分类号： H01F5/00 ,  H01F41/02

CPC分类号： H01L23/5227 ,  H01L21/768 ,  H01L23/5225 ,  H01L23/552 ,  H01L23/585 ,  H01L24/03 ,  H01L24/11 ,  H01L28/10 ,  H01L2224/02351 ,  H01L2224/0401 ,  H01L2224/06515 ,  Y10T29/4902

摘要： An inductor device and method of forming the inductor device are provided. In some embodiments the inductor device includes a post passivation interconnect (PPI) layer disposed and an under bump metallization (UBM) layer, each disposed over a substrate. The PPI layer forms a coil and dummy pads. The dummy pads are disposed around a substantial portion of the coil to shield the coil from electromagnetic interference. A first portion of the UBM layer is electrically coupled to the coil and configured to interface with an electrical coupling member.

摘要翻译： 提供一种形成电感器件的电感器件和方法。 在一些实施例中，电感器件包括设置在衬底上的后钝化互连（PPI）层和凸块下金属化（UBM）层。 PPI层形成线圈和虚拟垫。 虚拟焊盘围绕线圈的大部分设置，以屏蔽线圈免受电磁干扰。 UBM层的第一部分电耦合到线圈并且被配置为与电耦合构件相接合。

公开(公告)号：US08396789B1

公开(公告)日：2013-03-12

申请号：US12651666

申请日：2010-01-04

申请人： Agus Sudjianto ,  Peter B. Vechnak ,  Michelle Warholic ,  Meghan Alita Steach ,  Jie Chen

发明人： Agus Sudjianto ,  Peter B. Vechnak ,  Michelle Warholic ,  Meghan Alita Steach ,  Jie Chen

IPC分类号： G06Q40/00

CPC分类号： G06Q40/025

摘要： Embodiments of the present invention evaluate consumer spending and borrowing patterns and, based thereon, forecast changes in consumer failure to repay rates. Embodiments of the present invention then develop macroeconomic variables that reflect the forecasted changes in consumer failure to repay rates and implement those macroeconomic variables into credit-approval decision models. The implemented macroeconomic variables adjust the decision models' credit-approval thresholds to account for the forecasted changes in consumer failure to repay rates. For example, if forecasts indicate decreasing credit failure to repay rates, then macroeconomic variables are developed and implemented in decision models to reduce credit-approval thresholds, thereby reducing qualifying creditworthiness scores and making it easier to get credit. On the other hand, for example, if forecasts indicate increasing credit failure to repay rates, then macroeconomic variables are developed and implemented in decision models to increase credit-approval thresholds, thereby restricting access to credit and reducing future losses from consumer failures to repay.

摘要翻译： 本发明的实施例评估消费者支出和借款模式，并据此预测消费者未能偿还差价的变化。 然后，本发明的实施例开发出反映消费者未能偿还利率的预测变化的宏观经济变量，并将这些宏观经济变量实施为信用审批决策模型。 实施的宏观经济变量调整决策模型的信用审批阈值，以解决消费者未能偿还利率的预测变化。 例如，如果预测表明信贷未能偿还利率下降，则在决策模型中制定和实施宏观经济变量，以减少信贷审批门槛，从而降低合格信用评分，并使其更容易获得信贷。 另一方面，例如，如果预测表明贷款利率不断下降，那么在决策模型中制定和实施宏观经济变量，以增加信贷审批阈值，从而限制信贷获取和减少未来消费者未偿还的损失。

公开(公告)号：US20130011007A1

公开(公告)日：2013-01-10

申请号：US13617504

申请日：2012-09-14

申请人： Daniel Gregory Muriello ,  Stephen Charles Heise ,  Jie Chen

发明人： Daniel Gregory Muriello ,  Stephen Charles Heise ,  Jie Chen

IPC分类号： G06K9/00

CPC分类号： G06F21/44

摘要： Users of an online system are authenticated based on signatures of cameras that were used to capture images uploaded to the online system. Users of an online system upload photos taken from their cameras. The online system extracts characteristic information about the camera that captured the photos. This information includes a mapping of faulty pixels, metadata included with the photos, a naming convention, and the like. The online system stores an association between the user and the camera. This association is used for authentication of the user. For authentication, the user is asked to upload new photos taken from the camera that the user used previously. The information extracted from the newly uploaded photos is matched against stored information of cameras used previously by the user. The user is successfully authenticated if the camera used for the newly uploaded photos matches a previously stored camera.

摘要翻译： 在线系统的用户基于用于捕获上传到在线系统的图像的相机的签名进行身份验证。 在线系统的用户上传从相机拍摄的照片。 在线系统提取拍摄照片的相机的特征信息。 该信息包括错误像素的映射，照片附带的元数据，命名约定等。 在线系统存储用户和相机之间的关联。 该关联用于用户的认证。 对于认证，用户被要求上传用户以前使用的相机拍摄的新照片。 从新上传的照片提取的信息与用户先前使用的相机的存储信息相匹配。 如果用于新上传的照片的相机与先前存储的相机匹配，则用户已成功验证。

公开(公告)号：US08306256B2

公开(公告)日：2012-11-06

申请号：US12884137

申请日：2010-09-16

申请人： Daniel Gregory Muriello ,  Stephen Charles Heise ,  Jie Chen

发明人： Daniel Gregory Muriello ,  Stephen Charles Heise ,  Jie Chen

IPC分类号： G06K9/00

CPC分类号： G06F21/44

摘要： Users of an online system are authenticated based on signatures of cameras that were used to capture images uploaded to the online system. Users of an online system upload photos taken from their cameras. The online system extracts characteristic information about the camera that captured the photos. This information includes a mapping of faulty pixels, metadata included with the photos, a naming convention, and the like. The online system stores an association between the user and the camera. This association is used for authentication of the user. For authentication, the user is asked to upload new photos taken from the camera that the user used previously. The information extracted from the newly uploaded photos is matched against stored information of cameras used previously by the user. The user is successfully authenticated if the camera used for the newly uploaded photos matches a previously stored camera.

摘要翻译： 在线系统的用户基于用于捕获上传到在线系统的图像的相机的签名进行身份验证。 在线系统的用户上传从相机拍摄的照片。 在线系统提取拍摄照片的相机的特征信息。 该信息包括错误像素的映射，照片附带的元数据，命名约定等。 在线系统存储用户和相机之间的关联。 该关联用于用户的认证。 对于认证，用户被要求上传用户以前使用的相机拍摄的新照片。 从新上传的照片提取的信息与用户先前使用的相机的存储信息相匹配。 如果用于新上传的照片的相机与先前存储的相机匹配，则用户已成功验证。

公开(公告)号：US08292834B2

公开(公告)日：2012-10-23

申请号：US13293907

申请日：2011-11-10

申请人： Tarek Hessin Ahmed El-Bialy ,  Jie Chen ,  Ying Yin Tsui

发明人： Tarek Hessin Ahmed El-Bialy ,  Jie Chen ,  Ying Yin Tsui

IPC分类号： A61N7/00 ,  A61B8/00

CPC分类号： A61N7/00 ,  A61B2017/00106 ,  A61B2017/00734 ,  A61B2090/378 ,  A61C8/0006 ,  A61C19/06 ,  C12M35/04 ,  C12N13/00

摘要： Ultrasound stimulation devices and related techniques are disclosed. An ultrasound transducer for generating ultrasound energy is carried by a transducer housing that seals the transducer and may also include a positioning element for positioning the transducer proximate an application area to which generated ultrasound energy is to be applied. The transducer housing may also carry such components as a battery, a wireless receiver, and a controller. The same housing or a separate sensor housing may include an ultrasound sensor that provides feedback to the ultrasound transducer or its controller, illustratively through a wireless transmitter.

摘要翻译： 公开了超声刺激装置和相关技术。 用于产生超声能量的超声波换能器由传感器外壳承载，该换能器壳体密封换能器，并且还可以包括定位元件，用于将换能器定位在靠近生成的超声能量的应用区域。 传感器外壳还可以承载诸如电池，无线接收器和控制器的组件。 相同的壳体或单独的传感器壳体可以包括超声传感器，其通过无线发射器示意性地向超声换能器或其控制器提供反馈。

公开(公告)号：US20120227417A1

公开(公告)日：2012-09-13

申请号：US13498092

申请日：2010-09-30

申请人： Wei Chao ,  Jie Chen ,  Kunroing Zhuang ,  Jinlin Gao

发明人： Wei Chao ,  Jie Chen ,  Kunroing Zhuang ,  Jinlin Gao

IPC分类号： F25B9/14

CPC分类号： F25B9/14 ,  F25B9/10

摘要： A G-M refrigerator comprises a compressor (1), a gas inlet valve (2), an exhaust valve (3), a regenerator (4), a cylinder (5), a piston (6), a hot cavity (7), a cold cavity (8), a seal ring (9), a driving mechanism (10-12), an annular gap (13), a heat exchanger (14), an orifice valve (18) and a gas reservoir (19). By introducing a phase modulation mechanism, such as the orifice valve (18), the gas reservoir (19) and the like, the working way of gas in the annular gap (13) is changed to be the same with that of a pulse tube refrigerator with the phase modulation mechanism, expansion of the part of the gas is fully utilized for doing work so as to generate the cold effect, loss caused by gas leakage through the seal ring (9) is further eliminated and the performances of the G-M refrigerator are further improved.

摘要翻译： GM冰箱包括压缩机（1），进气阀（2），排气阀（3），再生器（4），气缸（5），活塞（6），热腔（7） 冷空腔（8），密封环（9），驱动机构（10-12），环形间隙（13），热交换器（14），节流阀（18）和气体储存器（19） 。 通过引入诸如节流阀（18），气体储存器（19）等的相位调制机构，将环形间隙（13）中的气体的工作方式改变为与脉冲管 具有相位调制机构的冰箱，部分气体的膨胀被充分利用于进行工作以产生冷效应，进一步消除了通过密封环（9）的气体泄漏造成的损失，并且GM冰箱的性能 进一步改善。

公开(公告)号：US08230730B2

公开(公告)日：2012-07-31

申请号：US13171309

申请日：2011-06-28

申请人： Fei Ma ,  Jie Chen ,  Yuanfeng Pang

发明人： Fei Ma ,  Jie Chen ,  Yuanfeng Pang

IPC分类号： G01M17/00

CPC分类号： G01M17/08

摘要： The present invention relates to a comprehensive test bed for vehicle body, which comprises an vehicle body static strength testing apparatus, an vehicle body air tightness testing apparatus, an vehicle coupler strength testing apparatus and an vehicle body mode testing apparatus, wherein the tested vehicle body is provided with a strain foil and a displacement sensor; and the strain foil and the displacement sensor are connected with a data acquisition system. The comprehensive test bed for the vehicle body can perform an vehicle body static strength test on various rail passenger vehicles, an vehicle body steel structure vibration mode test, an vehicle body partial assembly vibration mode test and an vehicle body air tightness test, and can realize strength tests on partial key components of the vehicle body (a transition vehicle coupler, a return vehicle coupler, an vehicle body chassis cross beam, a hoisting structure, an end structure, and the like). The application range of the test bed includes high speed railway train units, urban rail vehicles, railway ordinary vehicles, maglev trains and straddle type single-rail vehicles. The comprehensive test bed for the vehicle body has a wide application range and can automatically carry out various tests on the same test bed, so that the test bed realizes simple and convenient testing process and convenient operation, and saves labor force and labor time.

摘要翻译： 本发明涉及一种车身综合试验台，其包括车体静强度试验装置，车体气密性试验装置，车辆联接器强度试验装置以及车体模式试验装置，其特征在于， 设置有应变箔和位移传感器; 应变片和位移传感器与数据采集系统连接。 车身综合试验台可对各轨道客车进行车身静强试验，车身钢结构振动试验，车身部分组装振动试验及车身密封性试验，可实现 对车体的部分关键部件（过渡车辆联动器，返回车辆联接器，车身机架横梁，起重结构，端部结构等）进行强度试验。 试验台的应用范围包括高速铁路车辆，城市轨道车辆，铁路普通车辆，磁悬浮列车和跨骑式单轨车辆。 车体综合试验台具有广泛的应用范围，可以在同一试验台上自动进行各种试验，使试验台实现了简单方便的试验过程，操作方便，节省了劳动力和劳动时间。

公开(公告)号：US20120169005A1

公开(公告)日：2012-07-05

申请号：US12982987

申请日：2010-12-31

申请人： John Edward Borsuk ,  Jie Chen

发明人： John Edward Borsuk ,  Jie Chen

IPC分类号： B41F13/66 ,  B65H9/00 ,  B65H7/20

CPC分类号： B65H31/3081 ,  B42B4/00 ,  B42C1/125 ,  B65H31/34 ,  B65H37/04 ,  B65H2402/10 ,  B65H2408/12 ,  B65H2511/152 ,  B65H2801/27 ,  G03G15/6538 ,  B65H2220/01

摘要： A stapler system for an image forming apparatus according to one example embodiment includes a housing and a mounting device for mounting the housing to the image forming apparatus. A staple head is positioned within the housing for stapling media. A media sheet path is disposed within the housing for directing media received from the image forming apparatus to the staple head for stapling. When the housing is mounted on the image forming apparatus, a portion of the housing extends above an output bin of the image forming apparatus to permit delivery of stapled media from the housing to the output bin of the image forming apparatus.

摘要翻译： 根据一个示例性实施例的用于图像形成装置的订书机系统包括用于将外壳安装到图像形成装置的壳体和安装装置。 钉头定位在外壳内用于装订介质。 介质片路径设置在壳体内，用于将从图像形成装置接收的介质引导到钉头以进行装订。 当壳体安装在图像形成装置上时，壳体的一部分在图像形成装置的输出箱的上方延伸，以允许装订的介质从壳体传送到成像设备的出纸槽。

公开(公告)号：US20120142707A1

公开(公告)日：2012-06-07

申请号：US13151706

申请日：2011-06-02

申请人： Alicia Regueiro-Ren ,  Jacob Swidorski ,  Zheng Liu ,  Nicholas A. Meanwell ,  Sing-Yuen Sit ,  Jie Chen

发明人： Alicia Regueiro-Ren ,  Jacob Swidorski ,  Zheng Liu ,  Nicholas A. Meanwell ,  Sing-Yuen Sit ,  Jie Chen

IPC分类号： A61K31/235 ,  C07C63/66 ,  C07D257/04 ,  C07D215/50 ,  C07D333/40 ,  C07D213/64 ,  C07D239/28 ,  A61K31/194 ,  A61K31/196 ,  A61K31/41 ,  A61K31/47 ,  A61K31/381 ,  A61K31/4418 ,  A61K31/505 ,  A61P31/12 ,  A61P31/18 ,  A61P37/02 ,  C07C309/65 ,  C07C69/753

CPC分类号： C07J63/008

摘要： Compounds having drug and bio-affecting properties, their pharmaceutical compositions and methods of use are set forth. In particular, modified C-3 betulinic acid and other structurally related natural products derivatives that possess unique antiviral activity are provided as HIV maturation inhibitors. These compounds are useful for the treatment of HIV and AIDS.

摘要翻译： 阐述了具有药物和生物影响特性的化合物，其药物组合物和使用方法。 特别地，具有独特抗病毒活性的改良的C-3桦木酸和其他与结构相关的天然产物衍生物作为HIV成熟抑制剂提供。 这些化合物可用于治疗艾滋病毒和艾滋病。