公开(公告)号：US20090107495A1

公开(公告)日：2009-04-30

申请号：US11996431

申请日：2006-07-21

申请人： Henmei Ni ,  Yoshiyuki Uchida ,  Wataru Kamimura ,  Junzo Tanaka

发明人： Henmei Ni ,  Yoshiyuki Uchida ,  Wataru Kamimura ,  Junzo Tanaka

IPC分类号： A61K9/51 ,  A61M16/06 ,  B29C47/04

CPC分类号： A61K9/70 ,  A61K9/0075 ,  A61K9/1688 ,  A61K9/51 ,  A61M15/08 ,  A61M16/06 ,  A61M2205/0244

摘要： An object of the present invention is to provide an inhalation device by which nano-sized particles of a medicine are able to be stably present without aggregation even in air or the like where no dispersing solvent is present. A device for inhalation of medicine according to the present invention for solving such a problem is that where medicine particles in a nano- to micron-size are adhered to a matrix comprising a nano fiber to such an extent that the particles are detached by inspiration permeating through the matrix.

摘要翻译： 本发明的目的是提供一种吸入装置，通过该吸入装置，即使在不存在分散溶剂的空气等中，药物的纳米尺寸粒子能够稳定地存在而不会聚集。 根据本发明的用于吸入药物的用于解决这个问题的装置是，其中将纳米至微米尺寸的药物颗粒粘附到包含纳米纤维的基质上，使得颗粒通过吸收渗透 通过矩阵。

公开(公告)号：US20070254013A1

公开(公告)日：2007-11-01

申请号：US10588309

申请日：2005-02-01

申请人： Tetsushi Taguchi ,  Hisatoshi Kobayashi ,  Junzo Tanaka ,  Kazuo Tsubota ,  Naoshi Shinozaki ,  Shigeto Shimmura ,  Hideyuki Miyashita

发明人： Tetsushi Taguchi ,  Hisatoshi Kobayashi ,  Junzo Tanaka ,  Kazuo Tsubota ,  Naoshi Shinozaki ,  Shigeto Shimmura ,  Hideyuki Miyashita

IPC分类号： A61F2/14

CPC分类号： A61L27/3804 ,  A61L27/3604 ,  A61L27/3641 ,  A61L27/3687 ,  A61L27/3839 ,  A61L2430/16

摘要： [Object] A medical material that improves therapeutic effects in epithelial cells such as keratoconjunctival epithelial cells with the use of an amnion, and a process for producing the same are provided. [Solving Means] A medical material includes an amnion, which is a placental tissue, a polymer film bonded to one surface of the amnion and crosslinked, and cells adhered to the other surface of the amnion. A process for producing the medical material includes the steps of preparing an amnion from which the spongy layer is removed, bonding a biocompatible polymer film to one surface of the amnion followed by crosslinking, adhering epithelial stem cells to the other surface of the amnion, and proliferating epithelial cells from the epithelial stem cells on the surface of the amnion.

摘要翻译： 提供了一种使用羊膜改善上皮细胞如角膜结膜上皮细胞治疗效果的医疗材料及其制造方法。 [解决方案]药物材料包括羊膜，羊膜组织，与羊膜的一个表面结合并交联的聚合物膜，以及附着在羊膜的另一表面的细胞。 制造医疗材料的方法包括以下步骤：制备从其中除去海绵层的羊膜，将生物相容性聚合物膜粘合到羊膜的一个表面，然后交联，将上皮干细胞粘附到羊膜的另一个表面，以及 从羊膜表面的上皮干细胞增殖上皮细胞。

公开(公告)号：US07153938B2

公开(公告)日：2006-12-26

申请号：US11123203

申请日：2005-05-06

申请人： Masanori Kikuchi ,  Junzo Tanaka ,  Hisatoshi Kobayashi ,  Daisuke Shoji

发明人： Masanori Kikuchi ,  Junzo Tanaka ,  Hisatoshi Kobayashi ,  Daisuke Shoji

IPC分类号： A61K38/17

CPC分类号： A61L27/56 ,  A61L27/46 ,  C08L89/06

摘要： A method for producing a cross-linked apatite/collagen porous body comprising the steps of gelling and then freeze-drying a dispersion containing an apatite/collagen composite and collagen to form a porous body, and further cross-linking collagen in the porous body, and a cross-linked apatite/collagen porous body produced by this method.

摘要翻译： 一种交联磷灰石/胶原多孔体的制​​造方法，其特征在于，包括以下步骤：将含有磷灰石/胶原复合物和胶原的分散体凝胶化，然后冷冻干燥，形成多孔体，进一步与多孔体交联胶原， 和通过该方法生产的交联磷灰石/胶原多孔体。

公开(公告)号：US07031131B2

公开(公告)日：2006-04-18

申请号：US10490035

申请日：2002-10-08

申请人： Takahiro Kudo ,  Junzo Tanaka ,  Kimitada Ishikawa

发明人： Takahiro Kudo ,  Junzo Tanaka ,  Kimitada Ishikawa

IPC分类号： H02H3/08 ,  H02H9/02

CPC分类号： H02H3/08 ,  G01R15/205 ,  H02H1/0007 ,  H02H1/06

摘要： A current sensor which constitutes an overload protection apparatus and senses a current supplied from a power source to a load is constituted by providing a magnetic sensor having the effect of magnetic impedance (MI), an AC supply means which impresses AC on this sensor, a bias current supply means which supplies a bias current to a bias coil, a peak sensing means which senses the peak or a change in impedance of the magnetic sensor as a change in voltage, and a switch which selects the output of the peak sensing means in accordance with each phase. A holding means which holds switch outputs one after another and an amplification means are provided in common to enable current sensing for each phase. Thus, a range of current sensing is enlarged to reduce power consumption and cost.

摘要翻译： 构成过载保护装置的电流传感器通过提供具有磁阻抗（MI）的影响的磁传感器，对该传感器施加AC的AC供给装置， 向偏置线圈提供偏置电流的偏置电流供给装置，检测作为电压变化的磁传感器的峰值或阻抗变化的峰值检测装置，以及选择峰值检测装置的输出的开关 按照每个阶段。 保持一个接一个地保持开关输出的保持装置和放大装置被共同设置，以使每个相位能够进行电流感测。 因此，电流检测的范围被扩大以降低功耗和成本。

公开(公告)号：US20060072272A1

公开(公告)日：2006-04-06

申请号：US11282716

申请日：2005-11-21

申请人： Takahiro Kudo ,  Junzo Tanaka ,  Kimitada Ishikawa

发明人： Takahiro Kudo ,  Junzo Tanaka ,  Kimitada Ishikawa

IPC分类号： H02H3/08

CPC分类号： H02H3/08 ,  G01R15/205 ,  H02H1/0007 ,  H02H1/06

摘要： An over-current protection device is constituted of a current detection unit for detecting a current from a power-supply source to a load having a magnetism detection element with a magnetic impedance (MI) effect, an AC-current supply device for supplying an AC current to the detection element, a bias-current supply device for supplying a bias current to a bias coil, a peak detection device for detecting a peak of impedance of the magnetism detection element as a variation of voltage, and a switch corresponding to a phase for selecting an output of the peak detection device. In the current detection unit, a holding device for holding a switch output and an amplifier are disposed in common for detecting the current in each phase, thereby expanding a current detectable range and reducing power consumption and cost.

摘要翻译： 过电流保护装置由电流检测单元构成，电流检测单元用于检测从电源到具有磁阻抗（MI）效应的磁检测元件的负载的电流; AC电流供给装置， 检测元件的电流，用于向偏置线圈供给偏置电流的偏置电流供给装置，用于检测磁检测元件的阻抗峰值作为电压变化的峰值检测装置，以及对应于相位的开关 用于选择峰值检测装置的输出。 在电流检测单元中，用于保持开关输出的保持装置和放大器被共同设置，用于检测每相中的电流，从而扩大电流可检测范围并降低功耗和成本。

公开(公告)号：US20050042252A1

公开(公告)日：2005-02-24

申请号：US10937732

申请日：2004-09-10

申请人： Junzo Tanaka ,  Masanori Kikuchi ,  Noriichi Ito ,  Yoshinobu Mandai ,  Hiroko Matsumoto ,  Yoshihisa Koyama ,  Kazuo Takakuda

发明人： Junzo Tanaka ,  Masanori Kikuchi ,  Noriichi Ito ,  Yoshinobu Mandai ,  Hiroko Matsumoto ,  Yoshihisa Koyama ,  Kazuo Takakuda

IPC分类号： A61K33/06 ,  A61K33/42 ,  A61K38/39 ,  A61L27/46 ,  A61L27/58

CPC分类号： A61K33/06 ,  A61K33/42 ,  A61K38/39 ,  A61L27/46 ,  A61L27/58 ,  A61K2300/00 ,  C08L89/06

摘要： This invention relates to a method for regulating the biodegradability of composite biomaterials comprising calcium salt (particularly hydroxyapatite) and collagen, improved composite biomaterials obtained via such method, and a method for increasing bone mass with the use of such composite biomaterials.

摘要翻译： 本发明涉及一种调节包含钙盐（特别是羟基磷灰石）和胶原的复合生物材料的生物降解性的方法，通过这种方法获得的改进的复合生物材料以及使用这种复合生物材料增加骨量的方法。

公开(公告)号：US20050031698A1

公开(公告)日：2005-02-10

申请号：US10487706

申请日：2002-08-14

申请人： Shinichi Sotome ,  Toshimasa Uemura ,  Masanori Kikuchi ,  Kenichi Shinomiya ,  Junzo Tanaka

发明人： Shinichi Sotome ,  Toshimasa Uemura ,  Masanori Kikuchi ,  Kenichi Shinomiya ,  Junzo Tanaka

IPC分类号： A61K9/48 ,  A61K38/18 ,  A61K38/39 ,  A61K45/00 ,  A61K47/04 ,  A61K47/36 ,  A61K47/42 ,  A61K47/46 ,  A61K47/48 ,  A61K9/14

CPC分类号： B82Y5/00 ,  A61K38/1825 ,  A61K38/39 ,  A61K47/548 ,  A61K47/6435 ,  A61K47/6921 ,  A61K47/6929

摘要： Disclosed is a material for sustained chemical-release in vivo, which comprises a hydroxyapatite/collagen (HAp/Col) nanocomposite formed as a coprecipitate, and a chemical consisting at least one of a drug and a bioactive substance including a growth factor and a DNA enzyme. The hydroxyapatite (HAp) has a specific surface area in the range of 50 to 300 m2/g. The hydroxyapatite (HAp) and the collagen (Col) are combined in such a manner that the crystals of the hydroxyapatite (HAp) are oriented in the C-axis direction around the fibers of the collagen (Col). The chemical is carried on the surface of the hydroxyapatite (HAp), the surface of the collagen (Col) and in a hydrated water of the hydroxyapatite (HAp) and the collagen (Col). The sustained chemical-release material can be prepared in the form of a bioabsorbable capsule, or in the form of allowing in vivo administration by injection and in-vivo gelation after said administration.

摘要翻译： 公开了一种用于体内持续化学释放的材料，其包含形成为共沉淀物的羟基磷灰石/胶原（HAp / Col）纳米复合物，以及包含生物因子和DNA的药物和生物活性物质中的至少一种的化学物质 酶。 羟基磷灰石（HAp）的比表面积为50〜300m 2 / g。 将羟基磷灰石（HAp）和胶原（Col）以使得羟基磷灰石（HAp）的晶体在胶原（Col）的纤维周围的C轴方向取向的方式组合。 该化学物质载于羟基磷灰石（HAp）的表面，胶原蛋白（Col）的表面和羟基磷灰石（HAp）和胶原（Col））的水合水中。 持续的化学释放材料可以以生物可吸收胶囊的形式制备，或以所述给药后允许通过注射和体内凝胶化的体内施用的形式。

公开(公告)号：US4875967A

公开(公告)日：1989-10-24

申请号：US164898

申请日：1988-03-07

申请人： Osamu Mishima ,  Shinobu Yamaoka ,  Osamu Fukunaga ,  Junzo Tanaka ,  Koh Era

发明人： Osamu Mishima ,  Shinobu Yamaoka ,  Osamu Fukunaga ,  Junzo Tanaka ,  Koh Era

IPC分类号： B01J3/06 ,  C30B9/00

CPC分类号： C30B9/00 ,  B01J3/065 ,  C30B29/403 ,  B01J2203/0645 ,  B01J2203/066 ,  B01J2203/068 ,  Y10S148/113

摘要： A method for growing a single crystal of cubic boron nitride semiconductor in a growing container sealed under high pressure and high temperature conditions, which comprises dissolving in a dopant-containing boron nitride solvent a boron nitride starting material placed at a high temperature zone in the growing container, and providing a temperature gradient to the solvent so that the temperature dependence of the solubility is utilized to let the single crystal form and grow at a low temperature zone in the growing container.

摘要翻译： 一种用于在高压和高温条件下密封的生长容器中生长立方氮化硼半导体单晶的方法，其包括在含掺杂剂的氮化硼溶剂中溶解置于生长中的高温区的氮化硼原料 容器，并且向溶剂提供温度梯度，使得溶解度的温度依赖性被用于使单晶形成并在生长的容器中的低温区域生长。

公开(公告)号：US4371769A

公开(公告)日：1983-02-01

申请号：US62243

申请日：1979-07-30

申请人： Hirofumi Yoshimura ,  Junzo Tanaka ,  Nobuo Ikeda

发明人： Hirofumi Yoshimura ,  Junzo Tanaka ,  Nobuo Ikeda

IPC分类号： H01P1/02 ,  H05B6/70 ,  H05B11/00

CPC分类号： H05B6/707 ,  H05B6/6482 ,  H05B6/725

摘要： A microwave heating apparatus has a heating chamber in which an object is to be heated both dielectrically by microwave and by radiant energy. A microwave generator for generating microwaves is disposed above the heating chamber, and a radiant energy heater is located within the heating chamber. A rectangular wave guide extends between the generator and an opening in the chamber for guiding the microwaves generated by the generator into the heating chamber from above, the wave guide being bent generally in the shape of the letter Z and the portion of the wave guide other than the portion adjacent the opening into said heating chamber being spaced from the walls of the heating chamber. Thermal insulation is provided between the chamber and the portion of the wave guide spaced from the walls of the chamber.

摘要翻译： 微波加热装置具有加热室，在该加热室中，物体将通过微波和辐射能在介质上进行加热。 用于产生微波的微波发生器设置在加热室的上方，辐射能加热器位于加热室内。 矩形波导在发电机和腔室中的开口之间延伸，用于将发电机产生的微波从上方引入加热室，波导通常以Z字形的形式弯曲，波导部分的其他部分弯曲 比与加热室的开口相邻的部分与加热室的壁间隔开。 在腔室和波导管的与腔室壁间隔开的部分之间提供隔热。

公开(公告)号：US4347420A

公开(公告)日：1982-08-31

申请号：US158229

申请日：1980-06-10

申请人： Nobuo Ikeda ,  Junzo Tanaka ,  Hirofumi Yoshimura

发明人： Nobuo Ikeda ,  Junzo Tanaka ,  Hirofumi Yoshimura

IPC分类号： H05B6/76

CPC分类号： H05B6/763

摘要： An improved choke seal arrangement, in a microwave oven, in which a slit structure is provided to prevent leakage of microwave energy around the periphery of the door. The slit structure, which has been provided in one of the walls defining the choke cavity in the prior art choke seal arrangement, is provided in a door wall portion spaced apart from the choke cavity so as to facilitate mechanical formation of the choke cavity and also to prevent deformation of the choke cavity wall during use. The choke seal arrangement permits the gap between the wall of the choke cavity and the confronting inner wall of the heating chamber to be smaller than hitherto, and the microwave seal performance further improved.

摘要翻译： 在微波炉中提供了​​一种改进的扼流圈密封装置，其中提供狭缝结构以防止微波能量围绕门的周边泄漏。 在现有技术的扼流圈密封装置中设置在限定扼流腔的一个壁中的狭缝结构设置在与扼流腔间隔开的门壁部分中，以便于扼流腔的机械形成，并且还 以防止在使用期间扼流腔壁的变形。 扼流圈密封装置允许扼流腔的壁与加热室的相对的内壁之间的间隙比迄今小，并且微波密封性能进一步提高。