公开(公告)号：US20170182799A1

公开(公告)日：2017-06-29

申请号：US15456191

申请日：2017-03-10

申请人： Junji Nakai ,  Hiroyoshi Matsumoto ,  Masakazu Yoshida ,  Souichi Nakazawa ,  Tatsuro Watanabe ,  Hiroyuki Hiratsuka ,  Koji Nagai

发明人： Junji Nakai ,  Hiroyoshi Matsumoto ,  Masakazu Yoshida ,  Souichi Nakazawa ,  Tatsuro Watanabe ,  Hiroyuki Hiratsuka ,  Koji Nagai

IPC分类号： B41J11/00 ,  B41J2/01

CPC分类号： B41J11/002 ,  B41J2/01 ,  B41J2/07 ,  B41J11/0015

摘要： A printing apparatus includes a plasma treatment unit that performs plasma treatment on a surface of a treatment object to acidify at least the surface of the treatment object; and a recording unit that performs inkjet recording on the surface of the plasma treatment subjected to the plasma treatment by the plasma treatment unit.

公开(公告)号：US09242482B2

公开(公告)日：2016-01-26

申请号：US14642587

申请日：2015-03-09

申请人： Haruki Saitoh ,  Koji Nagai ,  Hiroyuki Hiratsuka ,  Satoshi Katoh

发明人： Haruki Saitoh ,  Koji Nagai ,  Hiroyuki Hiratsuka ,  Satoshi Katoh

IPC分类号： B41J2/01 ,  B41J29/393 ,  B41J11/00 ,  B41J2/21

CPC分类号： B41J11/009 ,  B41J2/21 ,  B41J11/0015 ,  G01J3/46

摘要： A pH detecting device includes a supplying unit to supply a pH indicator, with an inkjet head, to a surface of a material to be processed on which acidification is performed; a color information detector to detect color information of the pH indicator supplied to the surface of the material; and a pH specifying unit to specify a pH value of the surface of the material based on the color information.

摘要翻译： pH检测装置包括供给单元，用于向进行酸化的待处理材料的表面供给具有喷墨头的pH指示剂; 颜色信息检测器，用于检测供应给所述材料表面的pH指示剂的颜色信息; 以及pH指定单元，其基于颜色信息指定材料的表面的pH值。

公开(公告)号：US09120334B2

公开(公告)日：2015-09-01

申请号：US14596370

申请日：2015-01-14

申请人： Koji Nagai ,  Yukitaka Watarai

发明人： Koji Nagai ,  Yukitaka Watarai

IPC分类号： G01D11/00 ,  B41J11/00 ,  C09D11/30 ,  C09D11/40 ,  C09D11/322

CPC分类号： B41J11/0015 ,  C09D11/102 ,  C09D11/30 ,  C09D11/322 ,  C09D11/38 ,  C09D11/40

摘要： Provided is an image forming apparatus, including: a pretreatment unit configured to bring a surface of a recording medium into contact with plasma; and an image forming unit configured to eject an ink onto the recording medium to thereby form an image; wherein the ink contains a pigment, water, a water-soluble organic solvent, and resin particles, wherein the water-soluble organic solvent is an amide compound having an inorganic/organic value (I/O value) of 1.1 to 2.0, and wherein the resin particles are ether-based polyurethane resin particles and have an acid group amount of 2.0 meq/g or more.

摘要翻译： 提供了一种图像形成装置，包括：预处理单元，被配置为使记录介质的表面与等离子体接触; 以及图像形成单元，被配置为将墨喷射到记录介质上，从而形成图像; 其中所述油墨含有颜料，水，水溶性有机溶剂和树脂颗粒，其中所述水溶性有机溶剂是无机/有机值（I / O值）为1.1至2.0的酰胺化合物，并且其中 树脂粒子是醚类聚氨酯树脂粒子，酸基量为2.0meq / g以上。

公开(公告)号：US20120001976A1

公开(公告)日：2012-01-05

申请号：US13164955

申请日：2011-06-21

申请人： Satoshi Katoh ,  Wataru Takahashi ,  Koji Nagai

发明人： Satoshi Katoh ,  Wataru Takahashi ,  Koji Nagai

IPC分类号： B41J29/38

CPC分类号： B41J2/16526 ,  B41J11/007

摘要： An image forming apparatus includes an endless belt having holes facing a head and to transfer a recording medium in a transferring direction perpendicular to an array direction of nozzles in the head, a driving unit to drive the endless belt, a driving speed control unit to control a driving speed of the endless belt, and a maintenance discharge amount acquisition unit to acquire an amount of a recording liquid to be discharged from the nozzles of the head to allow the amount of the recording liquid to be passed through the holes in the endless belt for performing maintenance during a non-image forming operation. The driving speed control unit sets the driving speed of the endless belt based on the amount of the recording liquid to be discharged from the nozzles acquired by the maintenance discharge amount acquisition unit.

摘要翻译： 图像形成装置包括：环形带，其具有面向头部的孔，并且沿着与头部中的喷嘴的排列方向垂直的传送方向传送记录介质;驱动单元，驱动环形带;驱动速度控制单元，用于控制 环形带的驱动速度和维护排出量获取单元，用于从头部的喷嘴获取要排出的记录液体的量，以允许记录液体的数量通过环形带中的孔 用于在非图像形成操作期间执行维护。 驱动速度控制单元基于从由维护排出量获取单元获取的喷嘴排出的记录液体的量来设定环形带的驱动速度。

公开(公告)号：US20110148982A1

公开(公告)日：2011-06-23

申请号：US12965253

申请日：2010-12-10

申请人： Satoshi Katoh ,  Koji Nagai

发明人： Satoshi Katoh ,  Koji Nagai

IPC分类号： B41J2/165

CPC分类号： B41J2/16585

摘要： An image forming apparatus includes a recording head having a nozzle and configured to discharge droplets of a recording fluid via the nozzle onto a recording sheet in an image forming operation; a sheet transport unit configured to transport the recording sheet in a sheet transport direction; and a maintenance unit configured to perform a maintenance operation for the recording head. The maintenance unit is configured to be moved in a forward direction corresponding to the sheet transport direction and a backward direction opposite the forward direction. The maintenance unit performs the maintenance operation when the maintenance unit is moved in the backward direction.

摘要翻译： 图像形成装置包括具有喷嘴并被配置为在成像操作中经由喷嘴将记录流体的液滴排出到记录纸上的记录头; 纸张传送单元，其构造成在片材传送方向上传送记录片材; 以及维护单元，被配置为对记录头执行维护操作。 维护单元被构造成沿与纸张输送方向对应的向前方向和与向前方向相反的向后方向移动。 当维护单元向后移动时，维护单元执行维护操作。

公开(公告)号：US20090013901A1

公开(公告)日：2009-01-15

申请号：US12169341

申请日：2008-07-08

申请人： Keisuke ASADA ,  Koji Nagai

发明人： Keisuke ASADA ,  Koji Nagai

IPC分类号： C09D11/02 ,  C08K3/36

CPC分类号： C09D11/101

摘要： Provided is an active energy beam-curable ink capable of preventing ink flow by enhancing the separation resistance of the ink components at high temperatures without impairing the stability against viscosity changes due to high temperatures. The active energy beam-curable ink contains hydrophilic silica with a primary particle diameter of 100 nm or less. It is preferable that a specific surface of the hydrophilic silica be 280 m2/g or less. It is more preferable that the primary particle diameter and the specific surface of the hydrophilic silica be 28 nm or less and 190 m2/g or less, respectively. Moreover, the ink preferably contains a monomer having ethylene oxide units. The number of ethylene oxide units is preferably 6 to 19. The monomer content is preferably 0.02% by mass to 20% by mass with respect to the total mass of the ink.

摘要翻译： 本发明提供一种能够通过在高温下提高油墨成分的耐分离性而不损害由于高温引起的粘度变化的稳定性而能够防止油墨流动的活性能量光束固化型油墨。 活性能量束固化油墨含有一次粒径为100nm以下的亲水性二氧化硅。 亲水性二氧化硅的比表面优选为280m 2 / g以下。 更优选一次粒径和亲水性二氧化硅的比表面积分别为28nm以下，190m 2 / g以下。 此外，油墨优选含有具有环氧乙烷单元的单体。 环氧乙烷单元的数量优选为6〜19。相对于油墨的总质量，单体含量优选为0.02质量％〜20质量％。

公开(公告)号：US07098186B2

公开(公告)日：2006-08-29

申请号：US10525717

申请日：2003-08-28

申请人： Koji Nagai ,  Masatoshi Taniguchi ,  Nobuaki Shindo ,  Yoh Terada ,  Masamichi Mori ,  Nobuaki Amino ,  Ken-ichi Suzumura ,  Isao Takahashi ,  Mitsuo Amase

发明人： Koji Nagai ,  Masatoshi Taniguchi ,  Nobuaki Shindo ,  Yoh Terada ,  Masamichi Mori ,  Nobuaki Amino ,  Ken-ichi Suzumura ,  Isao Takahashi ,  Mitsuo Amase

IPC分类号： A61K38/12 ,  C07K2/00

CPC分类号： C07K5/0205 ,  A61K38/00 ,  C07K11/00

摘要： The present invention relates to a novel compound which is useful as an agent for prevention and treatment of diseases associated with HDAC, in particular, tumor or cell proliferative diseases. The depsipeptide compound or its pharmaceutically acceptable salt of the present invention has a good HDAC inhibitory activity and an inhibitory activity of cell proliferation against human cancer cells and, therefore, is useful in treatment and improvement of diseases and pathogenic conditions associated with histone acetylation, in particular, tumor or cell proliferative diseases.

摘要翻译： 本发明涉及一种新型化合物，其可用作预防和治疗与HDAC相关疾病，特别是肿瘤或细胞增殖性疾病的药剂。 本发明的前肽化合物或其药学上可接受的盐具有良好的HDAC抑制活性和对人癌细胞的细胞增殖的抑制活性，因此可用于治疗和改善与组蛋白乙酰化有关的疾病和病原性病症 特别是肿瘤或细胞增殖性疾病。

公开(公告)号：US07098024B2

公开(公告)日：2006-08-29

申请号：US10684656

申请日：2003-10-15

申请人： Koji Nagai ,  Nakako Arao ,  Kinya Souda ,  Kazuma Kamigiri ,  Masamichi Mori ,  Nobuaki Shindo ,  Haruo Seto ,  Kazuo Shin-Ya

发明人： Koji Nagai ,  Nakako Arao ,  Kinya Souda ,  Kazuma Kamigiri ,  Masamichi Mori ,  Nobuaki Shindo ,  Haruo Seto ,  Kazuo Shin-Ya

IPC分类号： C12N1/20 ,  A61K38/12

CPC分类号： C07K5/0205 ,  A61K35/00 ,  A61K38/00

摘要： This invention relates to a novel compound which has a cytotoxic activity and TGF-β like activity for human cancer cells and is useful as an antitumor agent and to a pharmaceutical composition which contains the same.

公开(公告)号：US20050063927A1

公开(公告)日：2005-03-24

申请号：US10502949

申请日：2003-01-29

申请人： Akira Nakagawa ,  Senji Takahashi ,  Toshitsugu Miyazaki ,  Yuuko Osanai ,  Kunio Kosaka ,  Koji Nagai ,  Nakako Arao ,  Kouichi Tanaka

发明人： Akira Nakagawa ,  Senji Takahashi ,  Toshitsugu Miyazaki ,  Yuuko Osanai ,  Kunio Kosaka ,  Koji Nagai ,  Nakako Arao ,  Kouichi Tanaka

IPC分类号： A61K8/60 ,  A61K8/99 ,  A61Q19/02 ,  C12P19/02 ,  C12P19/46 ,  C12R1/01 ,  A61K7/135 ,  C07H5/06 ,  C12N1/20

CPC分类号： C12R1/01 ,  A61K8/60 ,  A61K8/602 ,  A61K8/99 ,  A61Q19/02 ,  C12P19/46

摘要： There are provided a novel microorganism Enterobacter sp. B20 strain which produces (E)-4-(2-isocyanovinyl)phenyl α-rhamnopyranoside having a favorable effect of inhibiting melanogenesis and α-L-rhamnopyranoside produced thereby. This novel microorganism is a gram-negative bacillus isolated from soil and shows motility owing to polar flagellum. The α-L-rhamnopyranoside, which is produced by culturing the microorganism under aerobic conditions at a culture temperature of 10 to 37° C. and at a medium pH of about 5 to 9 usually for about 1 to 7 days, is useful as a highly safe and stable whitening agent.

摘要翻译： 提供了一种新型微生物肠杆菌属 B20菌株，其产生具有抑制黑素生成的有利效果的由（E）-4-（2-异氰酸基乙烯基）苯基α-鼠李糖吡喃糖苷生成的α-L-鼠李糖吡喃糖苷。 这种新型微生物是从土壤中分离的革兰氏阴性芽孢杆菌，由极鞭毛引起的运动性。 通过在需氧条件下在10〜37℃的培养温度和约5〜9的中等pH下培养约1〜7天来制备的α-L-鼠李糖苷可用作 高度安全稳定的美白剂。

公开(公告)号：US4764606A

公开(公告)日：1988-08-16

申请号：US890906

申请日：1986-07-28

申请人： Harumitsu Imai ,  Ken-ichi Suzuki ,  Koji Nagai ,  Shigeru Miyazaki ,  Kenji Abe ,  Isao Takahashi ,  Shigenobu Kadota ,  Koichi Tanaka

发明人： Harumitsu Imai ,  Ken-ichi Suzuki ,  Koji Nagai ,  Shigeru Miyazaki ,  Kenji Abe ,  Isao Takahashi ,  Shigenobu Kadota ,  Koichi Tanaka

IPC分类号： A61K31/545 ,  A61K31/546 ,  A61P31/04 ,  C07D501/57 ,  C12P35/06 ,  C12P35/08 ,  C12R1/38 ,  C12R1/645 ,  C07D501/36

CPC分类号： C12R1/38 ,  C12P35/06 ,  C12P35/08

摘要： A 7-formylaminocephalosporin compound represented by general formula (I): ##STR1## wherein R.sup.1 represents a carboxy group or an aminocarboxymethyl group ##STR2## R.sup.2 represents a hydrogen atom or a protective group for a carboxy group, andR.sup.3 represents a 5- or 6-membered heterocyclic group which may be substituted;or a salt thereof, and a process for producing the compound; The compounds are useful intermediates for other cephalosporin compounds having antibacterial activity, and themselves show antibacterial activity, as well.

摘要翻译： 由通式（I）表示的7-甲酰氨基头孢菌素化合物：其中R 1表示羧基或氨基羧基甲基R 2表示氢原子或羧基的保护基，R 3表示5-或 可被取代的6元杂环基; 或其盐，以及该化合物的制造方法。 这些化合物是具有抗菌活性的其它头孢菌素化合物的有用的中间体，它们本身也显示出抗菌活性。