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公开(公告)号：US20210069654A1
公开(公告)日：2021-03-11
申请号：US16953066
申请日：2020-11-19
Applicant: LIFE TECHNOLOGIES CORPORATION
Inventor： Michael E. Goodwin , Nephi D. Jones , Derik R. West
Abstract: A container assembly includes a flexible bag having an interior surface bounding a chamber and an opposing exterior surface. The bag has a bottom end wall that includes a first sparger and a second sparger. The first sparger and the second sparger each have a flexible first sheet overlying a flexible second sheet, the first sheet and the second sheet being secured together so as to form a sparging area bounded between the first sheet and the second sheet, at least a portion of the first sheet overlying the sparging area being gas permeable so that gas can pass from the sparging area, through the first sheet, and into the chamber.
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公开(公告)号：US20200248125A1
公开(公告)日：2020-08-06
申请号：US16853865
申请日：2020-04-21
Applicant: Life Technologies Corporation
Inventor： Nephi D. Jones , Christopher D. Brau
Abstract: A method for mixing a biological suspension includes disposing a biological suspension within a compartment of a container, the biological suspension comprising cells or microorganisms suspended within a nutrient growth medium; and rotating a first drive line and laterally spaced apart second drive line within the compartment of the container so as to cause the drive lines to twist into a helical configuration and mix the biological suspension.
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公开(公告)号：US20200231922A1
公开(公告)日：2020-07-23
申请号：US16715087
申请日：2019-12-16
Applicant: Life Technologies Corporation
Inventor： Christopher D. Brau , Nephi D. Jones , Benjamin R. Madsen , Michael E. Goodwin
Abstract: A system for performing a gas-liquid mass transfer includes a container bounding a compartment and having a top wall, a bottom wall, and an encircling sidewall extending therebetween. A tube has a first end and an opposing second end, the first end of the tube being disposed within the compartment of the container. A nozzle is disposed within the compartment of the container and has at least one outlet, the nozzle being coupled with the tube so that a gas can be passed through the tube and out the at least one outlet of the nozzle. The nozzle is sufficiently buoyant so that when a fluid is disposed within the compartment of the container, the nozzle floats on the fluid.
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公开(公告)号：US10711233B2
公开(公告)日：2020-07-14
申请号：US15374689
申请日：2016-12-09
Applicant: LIFE TECHNOLOGIES CORPORATION
Inventor： Clinton C. Staheli , Nephi D. Jones , Michael E. Goodwin
IPC: C12M3/00 , C12N1/00 , C12M1/00 , B01D5/00 , B01F3/04 , B01F7/00 , B01F7/16 , B01F7/18 , B01F15/00 , C12M1/06 , C12M1/12 , F28F21/06 , B01D47/05 , C12N1/10 , C12N1/12 , C12N1/14 , C12N1/20 , C12N5/00 , C12N5/04 , B01F7/22 , B01F15/06 , C12M1/02 , F28B1/02 , F28F3/12 , C12N5/10 , F28D21/00
Abstract: A bag assembly for use with a heat exchanger includes a flexible bag having of one or more sheets of polymeric material, the bag having a first end that bounds a first compartment and an opposing second end that bounds a second compartment, a support structure being disposed between the first compartment and the second compartment so that the first compartment is separated and isolated from the second compartment. A first inlet port, a first outlet port, and a first drain port are coupled with the flexible bag so as to communicate with the first compartment. A second inlet port, a second outlet port, and a second drain port are coupled with the flexible bag so as to communicate with the second compartment.
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公开(公告)号：US20190010435A1
公开(公告)日：2019-01-10
申请号：US16067495
申请日：2016-12-21
Applicant: LIFE TECHNOLOGIES CORPORATION , LIFE TECHNOLOGICES AG
Inventor： Lars Norderhaugh , Angel Varela-Rohena , Nephi D. Jones
Abstract: Methods of separating magnetic particles from a fluid include introducing a fluid mixture that includes a liquid media, a biological component, and magnetic particles into an internal compartment of a container through an inlet, allowing at least a portion of the mixture to travel around a partition formed within the internal compartment and then exit the internal compartment through an outlet on the opposite side of the partition, and applying a magnetic field to the mixture in the internal compartment so that the magnetic particles are retained within the container or internal compartment thereof by the magnetic field. The partition is formed by permanently or reversibly securing upper and lower container walls together, such as by welding or pressing, between the inlet and the outlet such that the media and biological component must flow around the partition and through the magnetic field to exit the internal compartment through the outlet.
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Patent Agency Ranking
46.发明申请公开(公告)号：US20180334648A1
公开(公告)日：2018-11-22
申请号：US16046426
申请日：2018-07-26
Applicant: LIFE TECHNOLOGIES CORPORATION
Inventor： Nephi D. Jones , Christopher D. Brau
Abstract: A method for filtering a gas includes delivering a gas into a compartment of a gas filter assembly; applying a partial vacuum to the gas filter assembly so that the partial vacuum assists in drawing the gas through a porous filter body of the gas filter assembly that is at least partially disposed within the compartment of the gas filter assembly; and regulating the application of the partial vacuum based on a pressure reading of the gas upstream of the gas filter assembly.
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公开(公告)号：US20170088806A1
公开(公告)日：2017-03-30
申请号：US15376362
申请日：2016-12-12
Applicant: LIFE TECHNOLOGIES CORPORATION , Baxalta Incorporated , Baxalta GmbH
Inventor： Kurt T. Kunas , Robert V. Oakley , Fauad F. Hasan , Michael E. Goodwin , Jeremy K. Larsen , Nephi D. Jones
CPC classification number: C12M23/14 , B01F7/001 , B01F7/1695 , B01F7/22 , B01F15/00006 , B01F15/00831 , B01F15/0085 , B01F2215/0073 , C12M23/00 , C12M23/06 , C12M23/26 , C12M23/28 , C12M27/02 , C12M29/06 , Y10T29/49826
Abstract: A reactor system includes a support housing having an interior surface bounding a chamber, the chamber having a vertically extending central longitudinal axis. A flexible bag is disposed within the chamber of the support housing and has an interior surface bounding a compartment. A mixing element is disposed within the compartment of the flexible bag. A drive element, such as a drive shaft, is secured the mixing element, wherein the mixing element is laterally offset from and/or is angled relative to the vertically extending central longitudinal axis of the support housing.
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48.发明授权Regulated vacuum off-gassing of gas filter for fluid processing system and related methods 有权用于流体处理系统的气体过滤器的调节真空脱气及相关方法公开(公告)号：US09457306B2
公开(公告)日：2016-10-04
申请号：US14508824
申请日：2014-10-07
Applicant: LIFE TECHNOLOGIES CORPORATION
Inventor： Nephi D. Jones , Christopher D. Brau
CPC classification number: C12M29/20 , B01D5/00 , B01D19/0005 , B01D19/0031 , B01D19/0036 , B01D46/0002 , B01D46/002 , B01D46/446 , B01D53/265 , C12M23/14 , C12M23/26 , C12M29/04 , C12M29/06 , C12M41/14 , C12M41/40 , C12M41/48
Abstract: A method for filtering a gas includes sparging a gas through a liquid within a compartment of a container. In one embodiment the container can comprise a flexible bag. The sparged gas is passed from the container through a gas filter of a filter assembly. A partial vacuum is applied to the gas filter so that the partial vacuum assists in drawing the gas through the gas filter.
Abstract translation: 用于过滤气体的方法包括通过容器的隔室内的液体喷射气体。 在一个实施例中，容器可以包括柔性袋。 喷射的气体从容器通过过滤器组件的气体过滤器。 部分真空被施加到气体过滤器，使得部分真空有助于通过气体过滤器抽吸气体。
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公开(公告)号：US20160158394A1
公开(公告)日：2016-06-09
申请号：US15042974
申请日：2016-02-12
Applicant: LIFE TECHNOLOGIES CORPORATION
Inventor： Michael E. Goodwin , Nephi D. Jones , Bradley H. Buchanan
Abstract: A system for sterilizing a fluid includes a sterilization container bounding a fluid flow path that can be coupled with a fluid source. The sterilization container is comprised of one or more polymeric walls. A beam generator is configured to direct a beam of electromagnetic radiation through at least a portion of the fluid flow path of the sterilization container, the beam of electromagnetic radiation being sufficient to sterilize a fluid within the fluid flow path.
Abstract translation: 用于对流体灭菌的系统包括限定可与流体源耦合的流体流动路径的灭菌容器。 灭菌容器由一个或多个聚合物壁组成。 束发生器被配置为引导电磁辐射束穿过消毒容器的流体流动路径的至少一部分，电磁辐射束足以对流体流动路径内的流体进行消毒。
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公开(公告)号：US09289522B2
公开(公告)日：2016-03-22
申请号：US14381551
申请日：2013-02-27
Applicant: LIFE TECHNOLOGIES CORPORATION
Inventor： Michael E. Goodwin , Nephi D. Jones , Bradley H. Buchanan
Abstract: A system for sterilizing a fluid includes a fluid source and a sterilization container bounding a fluid flow path that is in fluid communication with the fluid source. The sterilization container is comprised of one or more polymeric walls. An electron beam generator is configured to direct an electron beam through at least a portion of the fluid flow path of the sterilization container, the electron beam being sufficient to sterilize a fluid within the fluid flow path.
Abstract translation: 用于对流体灭菌的系统包括流体源和限定与流体源流体连通的流体流动路径的灭菌容器。 灭菌容器由一个或多个聚合物壁组成。 电子束发生器被配置为引导电子束通过灭菌容器的流体流动路径的至少一部分，电子束足以对流体流动路径内的流体进行消毒。
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