公开(公告)号：US20170105386A1

公开(公告)日：2017-04-20

申请号：US14918044

申请日：2015-10-20

申请人： Ying Wu

发明人： Ying Wu

IPC分类号： A01K5/01

CPC分类号： A01K5/0114

摘要： Disclosed is the pet feeder table for feeding pets in one or more bowls and in at least one of the ingredient container separately. The pet feeder table includes a top frame, a first sidewall, a second sidewall, a first bottom frame and a third sidewall. The top frame is having one or more bowl openings for receiving one or more bowls. The top frame is further having a left edge and a right edge and is inclined towards the surface. The first sidewall and the second sidewall are extending downwards from the left edge and the right edge respectively of the top frame. Further, the first sidewall is having a first front edge and a first rear edge greater in height than the first front edge. The second sidewall is having a second front edge and a second rear edge greater in height than the second front edge. The first bottom frame is placed on the surface configured for receiving the ingredient container and is adjacently extending outwards from the first sidewall. Further, the first bottom frame is having a first bottom edge. The third sidewall is having a third front edge and third rear edge greater in height than the third front edge. Further, the third sidewall is extending upwards from the first bottom edge for providing housing to the ingredient container.

公开(公告)号：US09293353B2

公开(公告)日：2016-03-22

申请号：US13658652

申请日：2012-10-23

申请人： Maolin Long ,  Alex Paterson ,  Ricky Marsh ,  Ying Wu ,  John Drewery

发明人： Maolin Long ,  Alex Paterson ,  Ricky Marsh ,  Ying Wu ,  John Drewery

IPC分类号： C23C16/00 ,  H01L21/306 ,  H01L21/67 ,  H05K9/00 ,  H01J37/32

CPC分类号： H01L21/67069 ,  H01J37/32651 ,  H05K9/00

摘要： A Faraday shield and a plasma processing chamber incorporating the Faraday shield is are provided. The plasma chamber includes an electrostatic chuck for receiving a substrate, a dielectric window connected to a top portion of the chamber, the dielectric window disposed over the electrostatic chuck, and a Faraday shield. The Faraday shield is disposed inside of the chamber and defined between the electrostatic chuck and the dielectric window. The Faraday shield includes an inner zone having an inner radius range that includes a first and second plurality of slots and an outer zone having an outer radius range that includes a third plurality of slots. The inner zone is adjacent to the outer zone. The Faraday shield also includes a band ring separating the inner zone and the outer zone, such that the first and second plurality of slots do not connect with the third plurality of slots.

摘要翻译： 提供了法拉第屏蔽和包含法拉第屏蔽的等离子体处理室。 等离子体室包括用于接收基板的静电卡盘，连接到腔室的顶部的介电窗口，设置在静电卡盘上的电介质窗口和法拉第屏蔽件。 法拉第屏蔽设置在室内并限定在静电卡盘和电介质窗口之间。 法拉第屏蔽包括具有包括第一和第二多个狭槽的内半径范围的内区和具有包括第三多个槽的外半径范围的外区。 内部区域与外部区域相邻。 法拉第屏蔽还包括分隔内区和外区的带环，使得第一和第二多个槽不与第三多个槽连接。

公开(公告)号：US09074206B2

公开(公告)日：2015-07-07

申请号：US13129289

申请日：2009-11-13

申请人： Ying Wu ,  Hongguang Zhu ,  Jian Li ,  Liang Xu ,  Wilhelmus F. J. Verhaegh ,  Yiping Ren ,  Angel Janevski ,  Vinay Varadan ,  Zhaoyong Li ,  Nevenka Dimitrova

发明人： Ying Wu ,  Hongguang Zhu ,  Jian Li ,  Liang Xu ,  Wilhelmus F. J. Verhaegh ,  Yiping Ren ,  Angel Janevski ,  Vinay Varadan ,  Zhaoyong Li ,  Nevenka Dimitrova

IPC分类号： C12Q1/68 ,  C12N15/11

CPC分类号： C12N15/111 ,  C12N2310/141 ,  C12N2320/10 ,  C12N2330/10 ,  C12N2330/31 ,  C12Q1/6816 ,  C12Q1/6886 ,  C12Q2600/158 ,  C12Q2600/178

摘要： The present invention relates compositions and methods for microRNA (miRNA) expression profiling of colorectal cancer. In particular, the invention relates to a diagnostic kit of molecular markers for identifying one or more mammalian target cells exhibiting or having a predisposition to develop colorectal cancer, the kit comprising a plurality of nucleic acid molecules, each nucleic acid molecule encoding a miRNA sequence, wherein one or more of the plurality of nucleic acid molecules are differentially expressed in the target cells and in one or more control cells, and wherein the one or more differentially expressed nucleic acid molecules together represent a nucleic acid expression signature that is indicative for the presence of or the predisposition to develop colorectal cancer. The invention further relates to corresponding methods using such nucleic acid expression signatures for identifying one or more mammalian target cells exhibiting or having a predisposition to develop colorectal cancer as well as for preventing or treating such a condition. Finally, the invention is directed to a pharmaceutical composition for the prevention and/or treatment of colorectal cancer.

摘要翻译： 本发明涉及用于结肠直肠癌的微小RNA（miRNA）表达谱的组合物和方法。 特别地，本发明涉及用于鉴定表现出或具有发生结肠直肠癌倾向的一种或多种哺乳动物靶细胞的分子标记用诊断试剂盒，所述试剂盒包含多个核酸分子，编码miRNA序列的每个核酸分子， 其中所述多个核酸分子中的一个或多个在靶细胞和一个或多个对照细胞中差异表达，并且其中所述一个或多个差异表达的核酸分子一起表示指示存在的核酸表达特征 或发生结肠直肠癌的倾向。 本发明还涉及使用这种核酸表达特征鉴定一种或多种表现出或具有发生结肠直肠癌倾向的哺乳动物靶细胞以及预防或治疗这种病症的相应方法。 最后，本发明涉及用于预防和/或治疗结肠直肠癌的药物组合物。

公开(公告)号：US20130005878A1

公开(公告)日：2013-01-03

申请号：US13538618

申请日：2012-06-29

申请人： Shaw Ling Hsu ,  Ying Wu ,  Christian C. Honeker ,  David J. Bravet ,  Darryl William

发明人： Shaw Ling Hsu ,  Ying Wu ,  Christian C. Honeker ,  David J. Bravet ,  Darryl William

IPC分类号： C08L27/24 ,  C08K5/3415

CPC分类号： C08K5/3415 ,  C08K5/0083 ,  C08L27/16 ,  C08L67/04

摘要： A composition includes a) a melt processable polymer including at least one chemical moiety having a partial charge; and b) a nucleating agent having a surface charge that is opposite the partial charge of the chemical moiety of the polymer, wherein the nucleating agent accelerates the rate of crystallization of the melt processable polymer; wherein the nucleating agent has a melting point greater than the melting point of the melt processable polymer. In an embodiment, a method of making the composition is also provided.

摘要翻译： 组合物包括a）包含至少一个具有部分电荷的化学部分的可熔融加工的聚合物; 和b）具有与聚合物的化学部分的部分电荷相反的表面电荷的成核剂，其中成核剂加速可熔融加工的聚合物的结晶速率; 其中成核剂的熔点大于可熔融加工的聚合物的熔点。 在一个实施方案中，还提供了制备该组合物的方法。

公开(公告)号：US08306184B2

公开(公告)日：2012-11-06

申请号：US11921294

申请日：2006-05-31

申请人： Sha X. Chang ,  Ying Wu

发明人： Sha X. Chang ,  Ying Wu

IPC分类号： G01N23/04 ,  H05G1/70 ,  A61N5/10

CPC分类号： A61N5/103 ,  A61N2005/1061

摘要： X-ray pixel beam array systems and methods for electronically shaping radiation fields and modulating radiation field intensity patterns for radiotherapy are disclosed. One exemplary pre-clinical system may include addressable electron field emitters (102, 104) that are operable to emit a plurality of electron pixel beams (106, 108, 110). Each electron pixel beam may correspond to an x-ray target (124) and x-ray pixel beam collimation aperture (136, 138) to convert a portion of energy associated with the electron pixel beam to a corresponding x-ray pixel beam (140, 142). Further, the x-ray pixel beam array collimator (130) forms a one-to-one correspondence between individual electron pixel beam and its corresponding x-ray pixel beam. One exemplary clinical system may include a high-energy electron source (1203), an n-stage scanning system (1210), x-ray pixel beam targets (1212), and an x-ray pixel beam array collimator (1214). A controller (1206) may sequentially direct electron beam pulses to predetermined x-ray pixel targets and produce an electronically controlled radiation field direction, pattern; and intensity pattern.

摘要翻译： 公开了X射线像素束阵列系统和用于电子地整形辐射场和调节辐射场强度模式用于放射治疗的方法。 一个示例性的临床前系统可以包括可操作以发射多个电子像素束（106,108,110）的可寻址电子场发射器（102,104）。 每个电子像素束可以对应于x射线靶（124）和x射线像素束准直孔（136,138），以将与电子像素束相关联的能量的一部分转换成对应的x射线像素束（140 ，142）。 此外，x射线像素束阵列准直器（130）在各个电子像素束与其对应的x射线像素束之间形成一一对应关系。 一个示例性的临床系统可以包括高能电子源（1203），n级扫描系统（1210），x射线像素束靶（1212）和x射线像素束阵列准直器（1214）。 控制器（1206）可以顺序地将电子束脉冲引导到预定的x射线像素目标并产生电子控制的辐射场方向图案; 和强度模式。

公开(公告)号：US20110119794A1

公开(公告)日：2011-05-19

申请号：US12741226

申请日：2008-11-19

申请人： Jianbo Yang ,  Yuping Lu ,  Ying Wu ,  Meimei Wang ,  Xuzhong Li ,  Fengshun Song ,  Yi Zhang ,  Xiufeng Wang ,  Ni Dahu

发明人： Jianbo Yang ,  Yuping Lu ,  Ying Wu ,  Meimei Wang ,  Xuzhong Li ,  Fengshun Song ,  Yi Zhang ,  Xiufeng Wang ,  Ni Dahu

IPC分类号： A01H5/10 ,  C07H21/04 ,  C12N15/63 ,  A01H5/00 ,  C12N5/10

CPC分类号： C12N15/8223

摘要： An isolated rice non-endosperm tissue expression promoter, OsTSP I, and the use thereof. The promoter comprises the defined sequence of 1785 by (SEQ ID NO: 1), given in the specification, or its fragment or variant, or a nucleotide sequence If which hybridizes to SEQ ID NO: 1, or its fragment or variant, under stringent conditions. The activity of OsTSP I is comfirmed by transgenic methods. As determined histochemically, OsTSP I reglulates GUS expression in a tissue-specific manner and is not active in endosperm tissues. The OsTSP I can be used as a powerful tool for the investigation and control of gene expression in rice and other crops. It is particularly advantageous for development of safe transgenic foods such as rice.

摘要翻译： 分离的水稻非胚乳组织表达启动子OsTSP I及其用途。 启动子包括在说明书中给出的（SEQ ID NO：1）所定义的序列1785或其片段或变体，或在严格条件下与SEQ ID NO：1或其片段或变体杂交的核苷酸序列 条件。 OsTSP I的活性由转基因方法证实。 按组织学方法测定，OsTSP I以组织特异性方式调节GUS表达，并且在胚乳组织中不起作用。 OsTSP可作为水稻和其他作物基因表达调查和控制的有力工具。 特别有利于开发安全的转基因食品如水稻。

公开(公告)号：US20100311641A1

公开(公告)日：2010-12-09

申请号：US12837525

申请日：2010-07-16

申请人： JOHN P. O'BRIEN ,  Hong Wang ,  Ying Wu

发明人： JOHN P. O'BRIEN ,  Hong Wang ,  Ying Wu

IPC分类号： A61K38/02 ,  C07K2/00 ,  C07K7/00 ,  C07K14/00 ,  A61Q11/00 ,  A61P31/00

CPC分类号： A61K8/64 ,  A61K2800/43 ,  A61K2800/57 ,  A61K2800/94 ,  A61Q3/00 ,  A61Q5/065 ,  A61Q11/00 ,  A61Q19/04

摘要： Peptides have been identified that bind with high affinity to body surfaces, such as, hair, skin, nails, teeth, gums, and oral cavity surfaces. Peptide-based body surface coloring reagents, preferably tooth coloring reagents, are formed by coupling a tooth binding peptide to a pigment binding peptide, either directly or through a spacer. The peptide-based body coloring reagents may be used in conjunction with pigments to color body surfaces.

摘要翻译： 已经鉴定出已经以高亲和力结合到身体表面，例如头发，皮肤，指甲，牙齿和口腔表面的肽。 通过将牙结合肽直接或通过间隔物偶联到颜料结合肽而形成基于肽的体表着色剂，优选牙齿着色剂。 基于肽的身体着色剂可以与颜料结合使用以使身体表面着色。

公开(公告)号：US20100260317A1

公开(公告)日：2010-10-14

申请号：US11921294

申请日：2006-05-31

申请人： Sha X. Chang ,  Ying Wu

发明人： Sha X. Chang ,  Ying Wu

IPC分类号： G01N23/04 ,  G21K1/02 ,  H01J35/00 ,  H05G2/00 ,  A61N5/10

CPC分类号： A61N5/103 ,  A61N2005/1061

摘要： X-ray pixel beam array systems and methods for electronically shaping radiation fields and modulating radiation field intensity patterns for radiotherapy are disclosed. One exemplary pre-clinical system may include addressable electron field emitters (102, 104) that are operable to emit a plurality of electron pixel beams (106, 108, 110). Each electron pixel beam may correspond to an x-ray target (124) and x-ray pixel beam collimation aperture (136, 138) to convert a portion of energy associated with the electron pixel beam to a corresponding x-ray pixel beam (140, 142). Further, the x-ray pixel beam array collimator (130) forms a one-to-one correspondence between individual electron pixel beam and its corresponding x-ray pixel beam. One exemplary clinical system may include a high-energy electron source (1203), an n-stage scanning system (1210), x-ray pixel beam targets (1212), and an x-ray pixel beam array collimator (1214). A controller (1206) may sequentially direct electron beam pulses to predetermined x-ray pixel targets and produce an electronically controlled radiation field direction, pattern; and intensity pattern.

摘要翻译： 公开了X射线像素束阵列系统和用于电子地整形辐射场和调节辐射场强度模式用于放射治疗的方法。 一个示例性的临床前系统可以包括可操作以发射多个电子像素束（106,108,110）的可寻址电子场发射器（102,104）。 每个电子像素束可以对应于x射线靶（124）和x射线像素束准直孔（136,138），以将与电子像素束相关联的能量的一部分转换成对应的x射线像素束（140 ，142）。 此外，x射线像素束阵列准直器（130）在各个电子像素束与其对应的x射线像素束之间形成一一对应关系。 一个示例性的临床系统可以包括高能电子源（1203），n级扫描系统（1210），x射线像素束靶（1212）和x射线像素束阵列准直器（1214）。 控制器（1206）可以顺序地将电子束脉冲引导到预定的x射线像素目标并产生电子控制的辐射场方向图案; 和强度模式。

公开(公告)号：US07790147B2

公开(公告)日：2010-09-07

申请号：US12174694

申请日：2008-07-17

申请人： Xueying Huang ,  Hong Wang ,  Ying Wu

发明人： Xueying Huang ,  Hong Wang ,  Ying Wu

IPC分类号： A61K8/64 ,  A61Q3/02

CPC分类号： C07K7/08 ,  A61K8/64 ,  A61K2800/57 ,  A61K2800/94 ,  A61Q3/00 ,  A61Q5/065 ,  A61Q5/12 ,  A61Q11/00 ,  A61Q19/00 ,  A61Q19/04 ,  C07K7/06

摘要： Peptides have been identified that bind with high affinity to hair, skin, and nails. Peptide-based hair conditioners, hair colorants, skin conditioners, skin colorants, and nail colorants are described. The peptide-based hair conditioners and hair colorants consist of a hair-binding peptide coupled to a hair conditioning agent or a coloring agent, respectively. The peptide-based skin conditioners and skin colorants consist of a skin-binding peptide coupled to a skin conditioning agent or a colorant, respectively. The peptide-based nail colorants consist of a nail-binding peptide coupled to a coloring agent. In all these compositions, the peptide may be directly coupled to the active agent or the coupling may be via a spacer. Personal care compositions containing these peptide-based conditioners and colorants are also described.

摘要翻译： 已经鉴定出以高亲和力结合头发，皮肤和指甲的肽。 描述了基于肽的护发素，头发着色剂，皮肤调理剂，皮肤着色剂和指甲着色剂。 基于肽的头发调理剂和毛发着色剂分别由与头发调理剂或着色剂偶联的毛发结合肽组成。 基于肽的皮肤调理剂和皮肤着色剂分别由与皮肤调理剂或着色剂偶联的皮肤结合肽组成。 基于肽的指甲着色剂由与着色剂偶联的指甲结合肽组成。 在所有这些组合物中，肽可以直接与活性剂偶联，或者偶联可以经由间隔物。 还描述了含有这些基于肽的调理剂和着色剂的个人护理组合物。

公开(公告)号：US20080317691A1

公开(公告)日：2008-12-25

申请号：US12174694

申请日：2008-07-17

申请人： XUEYING HUANG ,  Ying Wu ,  Hong Wang

发明人： XUEYING HUANG ,  Ying Wu ,  Hong Wang

IPC分类号： A61K8/64 ,  C40B30/00 ,  A61Q3/02 ,  C07K2/00

CPC分类号： C07K7/08 ,  A61K8/64 ,  A61K2800/57 ,  A61K2800/94 ,  A61Q3/00 ,  A61Q5/065 ,  A61Q5/12 ,  A61Q11/00 ,  A61Q19/00 ,  A61Q19/04 ,  C07K7/06

摘要： Peptides have been identified that bind with high affinity to hair, skin, and nails. Peptide-based hair conditioners, hair colorants, skin conditioners, skin colorants, and nail colorants based are described. The peptide-based hair conditioners and hair colorants consist of a hair-binding peptide coupled to a hair conditioning agent or a coloring agent, respectively. The peptide-based skin conditioners and skin colorants consist of a skin-binding peptide coupled to a skin conditioning agent or a colorant, respectively. The peptide-based nail colorants consist of a nail-binding peptide coupled to a coloring agent. In all these compositions, the peptide may be directly coupled to the active agent or the coupling may be via a spacer. Personal care compositions containing these peptide-based conditioners and colorants are also described.

摘要翻译： 已经鉴定出以高亲和力结合头发，皮肤和指甲的肽。 描述了基于肽的护发素，头发着色剂，皮肤调理剂，皮肤着色剂和指甲着色剂。 基于肽的头发调理剂和毛发着色剂分别由与头发调理剂或着色剂偶联的毛发结合肽组成。 基于肽的皮肤调理剂和皮肤着色剂分别由与皮肤调理剂或着色剂偶联的皮肤结合肽组成。 基于肽的指甲着色剂由与着色剂偶联的指甲结合肽组成。 在所有这些组合物中，肽可以直接偶联到活性剂上，或者偶联可以通过间隔物。 还描述了含有这些基于肽的调理剂和着色剂的个人护理组合物。