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公开(公告)号:US20210017546A1
公开(公告)日:2021-01-21
申请号:US17036601
申请日:2020-09-29
Applicant: NOVOZYMES A/S
Inventor: Randy Deinhammer , Suzanne Clark , Mauricio Quiros , John Matthews , Anne Glud Hjulmand , Chee Leong Soong , Tomoko Matsui , Shinobu Takagi
IPC: C12P7/06
Abstract: The present invention relates to processes for producing fermentation products from starch-containing material, wherein a thermostable alpha-amylase and optionally a thermostable protease are present and/or added during liquefaction. The invention also relates to a composition suitable for use in a process of the invention.
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公开(公告)号:US20190352629A1
公开(公告)日:2019-11-21
申请号:US16318496
申请日:2017-07-14
Applicant: NOVOZYMES A/S
Inventor: Keiichi Ayabe , Tomoko Matsui , Aki Tomiki , Yuma Kurakata , Esben Peter Friis , Jens Erik Nielsen , Roland Alexander Pache
Abstract: The present invention relates to protease variants, having improved properties compared to the parent protease, in particular variants of a serine protease belonging to family 53 derived from a strain of Meripilus giganteus. The variants according to the invention have in particular increased thermo-stability, e.g., increased residual activity after 30 min at a temperature in the range from 55 to 60° C. and/or increased thermal denaturation temperature, compared to the parent Meripilus giganteus protease. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.
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公开(公告)号:US20190271011A1
公开(公告)日:2019-09-05
申请号:US16407840
申请日:2019-05-09
Applicant: NOVOZYMES A/S
Inventor: Randy Deinhammer , Suzanne Clark , Mauricio Quiros , John Matthews , Anne Glud Hjulmand , Chee Leong Soong , Tomoko Matsui , Shinobu Takagi
IPC: C12P7/06
Abstract: The present invention relates to processes for producing fermentation products from starch-containing material, wherein a thermostable alpha-amylase and optionally a thermostable protease are present and/or added during liquefaction. The invention also relates to a composition suitable for use in a process of the invention.
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公开(公告)号:US10227613B2
公开(公告)日:2019-03-12
申请号:US14648477
申请日:2013-11-26
Applicant: NOVOZYMES A/S
Inventor: Randall Deinhammer , Joyce Craig , Tomoko Matsui , Shinobu Takagi , Suzanne Clark , John Matthews , Anne Glud Hjulmand , Chee-Leong Soong , Zhengfang Kang
IPC: C12P7/00 , C12P7/14 , C12N9/58 , C12P7/06 , C12P7/08 , C12N9/26 , C12P19/14 , C13K1/06 , C12N9/52 , C12N9/28 , C12N9/44 , C12N9/62
Abstract: The present invention relates to processes for producing fermentation products from starch-containing material, wherein an alpha-amylase and optionally a thermostable protease, pullulanase and/or glucoamylase are present and/or added during liquefaction, wherein a cellulolytic composition is present and/or added during fermentation or simultaneous saccharification and fermentation. The invention also relates to a composition suitable for use in a process of the invention.
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公开(公告)号:US10138473B2
公开(公告)日:2018-11-27
申请号:US14690937
申请日:2015-04-20
Applicant: NOVOZYMES A/S
Inventor: Tomoko Matsui , Allan Noergaard , Thomas Agersten Poulsen , John Matthews
Abstract: The present invention relates to proteases having at least 75% identity to a protease derived from Thermoascus aurantiacus and comprises at least one modification in the amino acid sequence thereof. These protease variants have improved thermostability. The invention also relates to DNA encoding these proteases, methods of their production, as well as the use thereof.
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公开(公告)号:US20180245105A1
公开(公告)日:2018-08-30
申请号:US15961269
申请日:2018-04-24
Applicant: NOVOZYMES A/S
Inventor: Randall Deinhammer , Joyce Craig , Tomoko Matsui , Shinobu Takagi , Suzanne Clark , John Matthews , Anne Glud Hjulmand , Chee-Leong Soong , Zhengfang Kang
IPC: C12P7/14 , C12N9/58 , C12P7/08 , C12N9/62 , C12N9/52 , C12P19/14 , C12N9/28 , C12N9/44 , C12P7/06 , C13K1/06 , C12N9/26
CPC classification number: C12P7/14 , C12N9/2414 , C12N9/2417 , C12N9/2457 , C12N9/52 , C12N9/58 , C12N9/62 , C12P7/06 , C12P7/08 , C12P19/14 , C12P2201/00 , C12P2203/00 , C13K1/06 , Y02E50/17
Abstract: The present invention relates to processes for producing fermentation products from starch-containing material, wherein an alpha-amylase and optionally a thermostable protease, pullulanase and/or glucoamylase are present and/or added during liquefaction, wherein a cellulolytic composition is present and/or added during fermentation or simultaneous saccharification and fermentation. The invention also relates to a composition suitable for use in a process of the invention.
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公开(公告)号:US09828595B2
公开(公告)日:2017-11-28
申请号:US14420399
申请日:2013-08-15
Applicant: Novozymes A/S
Inventor: Tomoko Matsui , Aki Tomiki , Allan Svendsen , Hanne Vang Hendriksen , Mary Ann Stringer , Keiichi Ayabe
CPC classification number: C12N9/82 , A23L5/25 , C12Y305/01001
Abstract: The present invention relates to asparaginase variants. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants. The invention further relates to a process of producing a fermentation product, comprising: liquefying a starch-containing material to dextrins with an alpha-amylase in the presence of an asparaginase of the invention; saccharifying the dextrins to a sugar with a glucoamylase; and fermenting the sugar using a fermenting organism.
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公开(公告)号:US20170240874A1
公开(公告)日:2017-08-24
申请号:US15590224
申请日:2017-05-09
Applicant: NOVOZYMES A/S
Inventor: Randall Deinhammer , Anne Glud Hjulmand , Joyce Craig , Guillermo Coward-Kelly , Tomoko Matsui , Shinobu Takagi , Suzanne Clark , John Matthews
CPC classification number: C12N9/242 , C12N9/2417 , C12N9/2428 , C12N9/58 , C12N9/62 , C12P7/06 , C12P7/14 , C12Y302/01001 , C12Y302/01003 , C12Y302/01041 , Y02E50/17
Abstract: The present invention relates to processes for producing fermentation products from starch-containing material, wherein a bacterial alpha-amylase, a raw starch hydrolyzing alpha-amylase and a carbohydrate-source generating enzyme are present and/or added during liquefaction. The invention also relates to compositions suitable for use in processes of the invention.
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公开(公告)号:US09677095B2
公开(公告)日:2017-06-13
申请号:US14351471
申请日:2012-10-09
Applicant: NOVOZYMES A/S
Inventor: Randall Deinhammer , Anne Glud Hjulmand , Joyce Craig , Guillermo Coward-Kelly , Tomoko Matsui , Shinobu Takagi , Suzanne Clark , John Matthews
CPC classification number: C12N9/242 , C12N9/2417 , C12N9/2428 , C12N9/58 , C12N9/62 , C12P7/06 , C12P7/14 , C12Y302/01001 , C12Y302/01003 , C12Y302/01041 , Y02E50/17
Abstract: The present invention relates to processes for producing fermentation products from starch-containing material, wherein a bacterial alpha-amylase, a raw starch hydrolyzing alpha-amylase and a carbohydrate-source generating enzyme are present and/or added during liquefaction. The invention also relates to compositions suitable for use in processes of the invention.
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公开(公告)号:US09611469B2
公开(公告)日:2017-04-04
申请号:US14627584
申请日:2015-02-20
Applicant: NOVOZYMES A/S
Inventor: Lars Kobberoee Skov , Leonardo De Maria , Tomoko Matsui
IPC: C12N9/96 , C12N9/16 , C12P7/00 , A61K38/46 , C12N15/82 , C12P7/14 , C12P21/00 , A23K10/16 , A23L33/195
CPC classification number: C12N9/96 , A23K10/16 , A23L33/195 , A61K38/46 , C12N9/16 , C12N15/8243 , C12P7/00 , C12P7/14 , C12P21/00 , C12Y301/03008 , C12Y301/03026 , C12Y301/03072
Abstract: The present invention relates to a method for producing phytase variants which has at least 74% identity to a phytase derived from Citrobacter braakii and comprises at least two additional disulfide bonds as compared to this phytase. These phytase variants have modified, preferably improved, properties, such as thermostability, temperature profile, pH profile, specific activity, performance in animal feed, reduced protease sensitiliby, and/or an modified glycosylation pattern. The invention also relates to the variants produced, DNA encoding these phytases, methods of their production, as well as the use thereof, e.g., in animal feed and animal feed additives.
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