公开(公告)号：US5906590A

公开(公告)日：1999-05-25

申请号：US873483

申请日：1997-06-12

申请人： Kulbir Singh Hunjan ,  Josef V. Koblish ,  Thomas P. Coen

发明人： Kulbir Singh Hunjan ,  Josef V. Koblish ,  Thomas P. Coen

IPC分类号： A61M25/01 ,  A61M25/092 ,  A61M37/00

CPC分类号： A61M25/0147 ,  A61M25/0136

摘要： A bidirectional catheter with a deflectable tip at a distal end includes a handle at a proximal end and a tubular member extending between the tip and the handle. The handle includes a first piston member slidably mounted in a handle base with proximal ends of steering wires secured in the handle. The steering wires extend through the tubular member with respective distal ends thereof secured to circumferentially spaced portions of the distal end tip. Axial displacement of the piston member in a second direction conversely urges deflection of the distal end tip in a second direction by tensioning the other wire relative to the first wire. The piston member can include another piston member slidable in the first piston member with the proximal ends of the steering wires secured in the first mentioned piston member and the handle member, respectively, and with the other piston member supporting a proximal end of the tubular member.

摘要翻译： 在远端具有可偏转尖端的双向导管包括在近端处的手柄和在尖端和手柄之间延伸的管状构件。 手柄包括可滑动地安装在手柄底座中的第一活塞构件，其中固定在手柄中的操纵线的近端。 操纵线延伸穿过管状构件，其相应的远端固定到远端尖端的周向间隔开的部分。 活塞构件在第二方向上的轴向位移相反地通过相对于第一线张紧另一条线来促使远端尖端在第二方向上的偏转。 活塞构件可以包括可在第一活塞构件中滑动的另一活塞构件，其中操纵线的近端分别固定在第一提及的活塞构件和手柄构件中，并且另一个活塞构件支撑管状构件的近端 。

公开(公告)号：US5715832A

公开(公告)日：1998-02-10

申请号：US395968

申请日：1995-02-28

申请人： Josef V. Koblish ,  Thomas P. Coen ,  George J. Klein

发明人： Josef V. Koblish ,  Thomas P. Coen ,  George J. Klein

IPC分类号： A61B10/00 ,  A61B10/06 ,  A61B17/00 ,  A61B17/28 ,  A61B18/14 ,  A61F2/00 ,  A61M25/01 ,  A61M25/092

CPC分类号： A61B10/06 ,  A61B18/1445 ,  A61B18/1492 ,  A61B10/02 ,  A61B2017/00044 ,  A61B2017/00243 ,  A61B2017/003 ,  A61B2017/2905 ,  A61B2017/2946 ,  A61B2018/00577 ,  A61B2018/00839 ,  A61B2018/126 ,  A61B2018/162 ,  A61F2210/0014 ,  A61M25/0147

摘要： A deflectable biopsy catheter for obtaining a tissue sample from a body cavity of a patient comprising: an axially elongated catheter shaft having proximal and distal portions respectively terminating at proximal and distal ends, the catheter shaft being sized and constructed to be advanced into a body cavity of a patient; a deflection wire coupled to the distal portion of the catheter shaft and extending within the catheter to the proximal end thereof; and a pair of biopsy jaws coupled to the distal end of the catheter shaft and having first and second opposed free cutting surfaces exposable for contact with a selected area of tissue within the patient's body cavity and movable with respect to each other to cut a tissue sample from the selected area of tissue. Schemes for obtaining samples from body cavities (e.g., the gastrointestinal tract, the heart, the intestines, the uterus, the muscles, the bile duct, and the esophagus) are disclosed. Schemes for treating tissue by ablation or by electro-coagulation are also disclosed.

公开(公告)号：US5562619A

公开(公告)日：1996-10-08

申请号：US138863

申请日：1993-10-19

申请人： Thomas F. Mirarchi ,  Josef V. Koblish ,  Kulbir S. Hunjan ,  Craig R. Kline ,  Thomas H. Peterson

发明人： Thomas F. Mirarchi ,  Josef V. Koblish ,  Kulbir S. Hunjan ,  Craig R. Kline ,  Thomas H. Peterson

IPC分类号： A61B5/0408 ,  A61B5/0478 ,  A61B5/0492 ,  A61B17/00 ,  A61B17/22 ,  A61B17/221 ,  A61B17/28 ,  A61B17/30 ,  A61B17/32 ,  A61B18/14 ,  A61B18/24 ,  A61F2/958 ,  A61M5/14 ,  A61M25/01 ,  A61M25/092 ,  A61M25/00 ,  A61B17/36

CPC分类号： A61M25/0136 ,  A61B17/221 ,  A61B17/2909 ,  A61B17/32056 ,  A61M25/0133 ,  A61M25/0147 ,  A61B18/24 ,  A61B2017/00849 ,  A61B2017/00853 ,  A61B2017/22038 ,  A61B2017/22051 ,  A61B2017/2212 ,  A61B2017/2215 ,  A61B2017/2912 ,  A61B2017/292 ,  A61B2017/301 ,  A61B2018/1407 ,  A61M2025/015 ,  A61M25/10

摘要： For achieving, e.g., an improved electrophysiology catheter for examination of the heart, or a catheter accessing the brain, the invention, in one aspect, features an elongated wound wire coil extending through the hollow catheter body of a steerable catheter, the coil constructed and arranged to enable the catheter body to withstand reactive compressive load without distortion during application of tension on the pull wire and to transmit torque from the proximal to the distal tip portion of the catheter to enhance fidelity of rotational positioning of the distal tip in response to rotational orientation of the proximal portion of the catheter. The coil is shown in frictional torque-transmitting relationship with the interior of the hollow shaft substantially along the common length of the catheter body when the catheter is bent. Steerable catheters with augmented throw for one-handed operation and important improvements in construction features are also shown.

摘要翻译： 为了实现例如用于检查心脏的改进的电生理学导管或进入大脑的导管，在一个方面，本发明的特征在于延伸穿过可导向导管的中空导管体的细长缠绕线圈，线圈构造和 布置成使得导管体能够在拉线处施加张力的同时承受反作用的压缩载荷而不会变形，并且从导管的近端到远端部分传递扭矩，以提高响应于旋转的远侧末端的旋转定位的保真度 导管的近端部分的取向。 当导管弯曲时，线圈以与导管主体的公共长度基本上沿着空心轴的内部的摩擦转矩传递关系示出。 还显示了具有单手操作的增大的导向导管和构造特征的重要改进。

公开(公告)号：US08945015B2

公开(公告)日：2015-02-03

申请号：US13735358

申请日：2013-01-07

申请人： Darrell L. Rankin ,  Josef V. Koblish ,  Szabolcs Deladi

发明人： Darrell L. Rankin ,  Josef V. Koblish ,  Szabolcs Deladi

IPC分类号： A61B8/00 ,  A61B18/14 ,  A61B8/08 ,  A61B18/12 ,  A61M5/00 ,  A61B8/12 ,  A61N7/00 ,  A61B17/32 ,  A61B5/00 ,  A61B17/00 ,  A61H23/02 ,  A61B19/00 ,  A61B17/02 ,  A61B18/00

CPC分类号： A61B18/1492 ,  A61B5/0044 ,  A61B5/0084 ,  A61B5/6852 ,  A61B5/6869 ,  A61B8/0883 ,  A61B8/12 ,  A61B8/4254 ,  A61B8/4281 ,  A61B8/445 ,  A61B8/4477 ,  A61B8/5207 ,  A61B8/54 ,  A61B17/320068 ,  A61B18/1206 ,  A61B2017/00243 ,  A61B2017/0237 ,  A61B2018/00029 ,  A61B2090/378 ,  A61B2090/3782 ,  A61H23/0245 ,  A61M5/00 ,  A61N7/00 ,  A61N2007/0004 ,  A61N2007/0043 ,  A61N2007/0078 ,  A61N2007/0082

摘要： Devices and systems for ultrasonically imaging tissue and performing ablation therapy are disclosed. An ablation probe for treating and imaging body tissue includes an ablation electrode tip with a number of acoustic openings and a plurality of ultrasonic imaging sensors disposed within an interior lumen of the tip. The ultrasonic imaging sensors are supported within the interior lumen via an insert equipped with a number of recesses that receive the ultrasonic imaging sensors. An acoustically transparent shell disposed between the ultrasonic imaging sensors and the acoustic openings forms a fluid channel in the acoustic pathway of the sensors. During an ablation procedure, cooling fluid from an external fluid source is delivered through the fluid channel, providing an acoustic coupling effect between the ultrasonic imaging sensors and the surrounding body tissue.

摘要翻译： 公开了用于组织超声成像和进行消融治疗的装置和系统。 用于治疗和成像身体组织的消融探针包括具有多个声学开口的消融电极末端和设置在尖端的内腔内的多个超声成像传感器。 超声波成像传感器经由插入件配备有多个容纳超声波成像传感器的凹部的内腔内支撑。 设置在超声波成像传感器和声学开口之间的声透明壳体在传感器的声学通路中形成流体通道。 在消融过程中，来自外部流体源的冷却流体通过流体通道输送，从而在超声波成像传感器和周围的身体组织之间提供声学耦合效应。

公开(公告)号：US08423115B2

公开(公告)日：2013-04-16

申请号：US13557038

申请日：2012-07-24

申请人： Josef V. Koblish

发明人： Josef V. Koblish

IPC分类号： A61B5/04

CPC分类号： A61M25/0147 ,  A61B5/042 ,  A61B5/0422 ,  A61B5/6852

摘要： An electrophysiology catheter introduced through the groin and inferior vena cava into the right side of the heart comprises an elongate flexible shaft having a steerable distal section and a prolapsing section located proximally of the distal section. The distal section is inserted into the coronary sinus and a back-steering force is applied to the catheter to anchor the distal section therein, after which the catheter is further advanced to prolapse the prolapsing section against the high right atrium. Electrical pathways in both the coronary sinus and the high right atrium are mapped using respective electrode pairs carried on the distal and prolapsing sections of the catheter.

摘要翻译： 通过腹股沟和下腔静脉导入心脏的右侧的电生理学导管包括细长的柔性轴，其具有可操纵的远侧部分和位于远端部分的近侧的脱垂部分。 将远端部分插入冠状窦中，并将后向转向力施加到导管上以将远端部分固定在其中，之后导管进一步前进以使脱垂部分抵靠高右心房脱垂。 使用在导管的远端和脱垂部分上承载的各自的电极对来映射冠状窦和高右心房两者中的电通路。

公开(公告)号：US08229538B2

公开(公告)日：2012-07-24

申请号：US12838285

申请日：2010-07-16

申请人： Josef V. Koblish

发明人： Josef V. Koblish

IPC分类号： A61B5/04

CPC分类号： A61M25/0147 ,  A61B5/042 ,  A61B5/0422 ,  A61B5/6852

摘要： An electrophysiology catheter introduced through the groin and inferior vena cava into the right side of the heart comprises an elongate flexible shaft having a steerable distal section and a prolapsing section located proximally of the distal section. The distal section is inserted into the coronary sinus and a back-steering force is applied to the catheter to anchor the distal section therein, after which the catheter is further advanced to prolapse the prolapsing section against the high right atrium. Electrical pathways in both the coronary sinus and the high right atrium are mapped using respective electrode pairs carried on the distal and prolapsing sections of the catheter.

摘要翻译： 通过腹股沟和下腔静脉导入心脏的右侧的电生理学导管包括细长的柔性轴，其具有可操纵的远侧部分和位于远端部分的近侧的脱垂部分。 将远端部分插入冠状窦中，并将后向转向力施加到导管上以将远端部分固定在其中，之后导管进一步前进以使脱垂部分抵靠高右心房脱垂。 使用在导管的远端和脱垂部分上承载的各自的电极对来映射冠状窦和高右心房两者中的电通路。

公开(公告)号：US20090099564A1

公开(公告)日：2009-04-16

申请号：US12175433

申请日：2008-07-17

申请人： Josef V. Koblish ,  Anant V. Hegde ,  David K. Swanson

发明人： Josef V. Koblish ,  Anant V. Hegde ,  David K. Swanson

IPC分类号： A61B18/18 ,  A61M25/10

CPC分类号： A61B18/1492 ,  A61B5/0422 ,  A61B2018/00065 ,  A61B2018/00083 ,  A61B2018/00095 ,  A61B2018/00214 ,  A61B2018/0022 ,  A61B2018/00238 ,  A61B2018/00577 ,  A61B2018/00839 ,  A61B2090/065 ,  A61B2218/002

摘要： A probe that facilitates the creation of lesions in bodily tissue. The probe includes a relatively short shaft and an inflatable therapeutic element.

摘要翻译： 有助于在身体组织中产生损伤的探针。 探针包括相对短的轴和可膨胀的治疗元件。

公开(公告)号：US07474909B2

公开(公告)日：2009-01-06

申请号：US11625311

申请日：2007-01-20

申请人： Huy D. Phan ,  David K. Swanson ,  Josef V. Koblish ,  Russell B. Thompson ,  Thomas R. Jenkins

发明人： Huy D. Phan ,  David K. Swanson ,  Josef V. Koblish ,  Russell B. Thompson ,  Thomas R. Jenkins

IPC分类号： A61B5/02 ,  A61B18/14

CPC分类号： A61B18/1492 ,  A61B18/08 ,  A61B2018/00065 ,  A61B2018/00083 ,  A61B2018/00095 ,  A61B2018/0016 ,  A61B2018/00214 ,  A61B2018/00238 ,  A61B2018/00267 ,  A61B2018/00273 ,  A61B2018/00351 ,  A61B2018/00577 ,  A61B2018/1467 ,  A61M2025/105 ,  A61M2025/1086

摘要： A probe that may be used to create circumferential lesions in body tissue and, in some implementations, may also be used to perform mapping functions. The probe includes a collapsible/expandable structure that supports electrodes or other operative elements against the body tissue.

摘要翻译： 可用于在身体组织中产生周向损伤的探针，并且在一些实施方式中也可以用于执行映射功能。 探针包括支撑电极或抵抗身体组织的其它手术元件的可折叠/可扩展结构。

公开(公告)号：US07184811B2

公开(公告)日：2007-02-27

申请号：US11098189

申请日：2005-04-04

申请人： Huy D. Phan ,  David K. Swanson ,  Josef V. Koblish ,  Russell B. Thompson ,  Thomas R. Jenkins

发明人： Huy D. Phan ,  David K. Swanson ,  Josef V. Koblish ,  Russell B. Thompson ,  Thomas R. Jenkins

IPC分类号： A61B5/042 ,  A61B18/14

CPC分类号： A61B18/1492 ,  A61B18/08 ,  A61B2018/00065 ,  A61B2018/00083 ,  A61B2018/00095 ,  A61B2018/0016 ,  A61B2018/00214 ,  A61B2018/00238 ,  A61B2018/00267 ,  A61B2018/00273 ,  A61B2018/00351 ,  A61B2018/00577 ,  A61B2018/1467 ,  A61M2025/105 ,  A61M2025/1086

摘要： A probe that may be used to create circumferential lesions in body tissue and, in some implementations, may also be used to perform mapping functions. The probe includes a collapsible/expandable structure that supports electrodes or other operative elements against the body tissue.

摘要翻译： 可用于在身体组织中产生周向损伤的探针，并且在一些实施方式中也可以用于执行映射功能。 探针包括支撑电极或抵抗身体组织的其它手术元件的可折叠/可扩展结构。

公开(公告)号：US06542781B1

公开(公告)日：2003-04-01

申请号：US09447186

申请日：1999-11-22

申请人： Josef V. Koblish ,  Russell B. Thompson ,  Thomas R. Jenkins ,  Anant V. Hegde

发明人： Josef V. Koblish ,  Russell B. Thompson ,  Thomas R. Jenkins ,  Anant V. Hegde

IPC分类号： A61N100

CPC分类号： A61B18/1492 ,  A61B2018/00065 ,  A61B2018/00077 ,  A61B2018/00113 ,  A61B2018/00148 ,  A61B2018/00214 ,  A61B2018/00375 ,  A61B2018/00797 ,  A61B2018/00821 ,  A61B2018/1407 ,  A61B2018/1435 ,  A61B2018/1467

摘要： A probe that facilitates the creation of circumferential lesions in body tissue. The probe includes a elongate body and a loop structure, in the form of a helical structure or other loop structure, that supports electrodes or other operative elements against the body tissue.