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    Flowable Carrier Matrix
    47.
    发明申请
    Flowable Carrier Matrix 有权
    流动载体矩阵

    公开(公告)号：US20100112069A1

    公开(公告)日：2010-05-06

    申请号：US12634323

    申请日：2009-12-09

    申请人： Neil Beals ,  Jeffrey L. Scifert ,  Scott D. Boden

    发明人： Neil Beals ,  Jeffrey L. Scifert ,  Scott D. Boden

    IPC分类号： A61K9/14 ,  A61P43/00

    CPC分类号： A61K9/0024 ,  A61K9/0085 ,  A61K38/177 ,  A61K38/1774 ,  A61K38/18 ,  A61K38/1825 ,  A61K38/1841 ,  A61K38/1858 ,  A61K38/1866 ,  A61K38/1875 ,  A61K38/19 ,  A61K38/30 ,  A61K47/42 ,  A61L27/24 ,  A61L27/54 ,  A61L27/56 ,  A61L2300/414

    摘要： A carrier matrix may be delivered to a target position within a patient in a minimally invasive manner by first cutting a collagen sponge sheet into a plurality of relatively small pieces. These pieces are sized so that, when wet, they are capable of flowing through a cannula and/or reduced-diameter syringe tip. The pieces are placed into a syringe and wetted, say with a morphogenic solution, and optionally mixed with a bulking material, which is similarly sized to fit through the cannula. The thoroughly mixed and wetted product forms a viscous aggregate which may then be injected into the patient at the target site.

    摘要翻译： 通过首先将胶原海绵片切割成多个相对小的片，可以以微创方式将载体基质递送到患者体内的目标位置。 这些件的尺寸使得在潮湿时它们能够流过套管和/或减小直径的针头。 将片放置在注射器中并用形态发生溶液润湿，并且可选地与填充材料混合，膨胀材料的尺寸类似于穿过套管。 充分混合和润湿的产品形成粘性聚集体，然后可以在目标部位将其注入患者体内。

    Instrumentation to Facilitate Access into the Intervertebral Disc Space and Introduction of Materials Therein
    49.
    发明申请
    Instrumentation to Facilitate Access into the Intervertebral Disc Space and Introduction of Materials Therein 审中-公开
    便于进入椎间盘空间的仪器和其中的材料引入

    公开(公告)号：US20090099660A1

    公开(公告)日：2009-04-16

    申请号：US11869991

    申请日：2007-10-10

    申请人： Jeffrey L. Scifert ,  Scott D. Boden

    发明人： Jeffrey L. Scifert ,  Scott D. Boden

    IPC分类号： A61F2/44 ,  A61B17/00 ,  A61F5/00 ,  A61B1/00 ,  A61B17/58 ,  A61B19/00

    CPC分类号： A61B17/025 ,  A61B6/505 ,  A61B17/1604 ,  A61B17/1671 ,  A61B2017/00539 ,  A61B2017/0256 ,  A61F2/4455 ,  A61F2/4611 ,  A61F2002/444

    摘要： Methods for facilitating access to the intervertebral disc to deliver materials for disc repair are disclosed. The methods may be used to replace or augment nucleus pulposus as well as to perform interbody fusion procedures. These methods include providing access to the intervertebral disc space by drilling a channel through a vertebral bone, optionally accessing the intervertebral disc space to at least partially remove the disc tissue through the channel in the vertebrae; delivering a disc repairing material to the intervertebral disc space and back-filling the channel in the vertebrae with a channel sealing material. The methods may further comprise distracting the intervertebral height and inserting a restrictor into the channel in the vertebrae. Kits for practicing these methods are also disclosed.

    摘要翻译： 公开了便于进入椎间盘以输送用于椎间盘修复的材料的方法。 该方法可用于替代或增加髓核以及进行体内融合程序。 这些方法包括：通过穿过椎骨钻通道，提供对椎间盘空间的通路，任选地进入椎间盘空间以至少部分地通过椎骨中的通道去除椎间盘组织; 将椎间盘修复材料递送到椎间盘间隙，并用通道密封材料对椎骨中的通道回填。 所述方法还可以包括使椎间高度分散并将节流器插入椎骨的通道中。 还披露了用于实施这些方法的套件。

    Flowable carrier matrix
    50.
    发明申请
    Flowable carrier matrix 有权
    可流动载体矩阵

    公开(公告)号：US20080038351A1

    公开(公告)日：2008-02-14

    申请号：US11504363

    申请日：2006-08-14

    申请人： Neal Beals ,  Jeffrey L. Scifert ,  Scott D. Boden

    发明人： Neal Beals ,  Jeffrey L. Scifert ,  Scott D. Boden

    IPC分类号： A61K38/18 ,  A61K9/14

    CPC分类号： A61K9/0024 ,  A61K9/0085 ,  A61K38/177 ,  A61K38/1774 ,  A61K38/18 ,  A61K38/1825 ,  A61K38/1841 ,  A61K38/1858 ,  A61K38/1866 ,  A61K38/1875 ,  A61K38/19 ,  A61K38/30 ,  A61K47/42 ,  A61L27/24 ,  A61L27/54 ,  A61L27/56 ,  A61L2300/414

    摘要： A carrier matrix may be delivered to a target position within a patient in a minimally invasive manner by first cutting a collagen sponge sheet into a plurality of relatively small pieces. These pieces are sized so that, when wet, they are capable of flowing through a cannula and/or reduced-diameter syringe tip. The pieces are placed into a syringe and wetted, say with a morphogenic solution, and optionally mixed with a bulking material, which is similarly sized to fit through the cannula. The thoroughly mixed and wetted product forms a viscous aggregate which may then be injected into the patient at the target site.

    摘要翻译： 通过首先将胶原海绵片切割成多个相对小的片，可以以微创方式将载体基质递送到患者体内的目标位置。 这些件的尺寸使得在潮湿时它们能够流过套管和/或减小直径的针头。 将片放置在注射器中并用形态发生溶液润湿，并且可选地与填充材料混合，膨胀材料的尺寸类似于穿过套管。 充分混合和润湿的产品形成粘性聚集体，然后可以在目标部位将其注入患者体内。