摘要:
Substituted bicyclic heteroaryls and compositions containing them, for the treatment of general inflammation, arthritis, rheumatic diseases, osteoarthritis, inflammatory bowel disorders, inflammatory eye disorders, inflammatory or unstable bladder disorders, psoriasis, skin complaints with inflammatory components, chronic inflammatory conditions, including but not restricted to autoimmune diseases such as systemic lupus erythematosis (SLE), myestenia gravis, rheumatoid arthritis, acute disseminated encephalomyelitis, idiopathic thrombocytopenic purpura, multiples sclerosis, Sjoegren's syndrome and autoimmune hemolytic anemia, allergic conditions including all forms of hypersensitivity, The present invention also enables methods for treating cancers that are mediated, dependent on or associated with p110δ activity, including but not restricted to leukemias, such as Acute Myeloid leukemia (AML) Myelodysplastic syndrome (MDS) myelo-proliferative diseases (MPD) Chronic Myeloid Leukemia (CML) T-cell Acute Lymphoblastic leukaemia (T-ALL) B-cell Acute Lymphoblastic leukaemia (B-ALL) Non Hodgkins Lymphoma (NHL) B-cell lymphoma and solid tumors, such as breast cancer.
摘要:
A control procedure operates an expansion valve of an air conditioning system. The control procedure utilizes a first control procedure to bring a calculated superheat value within a range of a target superheat value, and a second control procedure to cause the calculated superheat value to match the target superheat value. Both the first and second control procedures preferably use Proportional, Integral, Derivative control algorithms.
摘要:
Computer-readable media, systems, and methods for intelligent information display are described. In embodiments, a display environment is monitored for one or more audience data and, upon receiving the one or more audience data, display information is processed in accordance with the one or more audience data and the processed display information is presented. In various embodiments, the audience data includes user gestures that indicate a communication with the intelligent information display, such as gestures indicating a mouse motion or a mouse click. In various other embodiments, the audience data includes demographic indicia such as the typical gender and/or typical age of an audience in a display environment.
摘要:
The present invention provides macrocyclic compounds useful as therapeutic agents. More particularly, these compounds are useful as anti-infective, anti-proliferative, anti-inflammatory, and prokinetic agents.
摘要:
A method, a system and recording medium for maintaining the order of nodes in a hierarchical document. The method may select the maximum and the minimum number of children for each node, build an auxiliary ordered tree having at least as many leaves as atoms within the hierarchical document based upon the selected maximum and minimum number of children for each node, attach the atoms to the leaves of the auxiliary ordered tree, and label each of the nodes in the auxiliary ordered tree.
摘要:
A system of protecting data in write-back cache between storage systems and the method thereof are employed to protect data in the write-back cache between a first storage system and a second storage system. The system adds, updates, or deletes the data in the second storage system backed up from the write-back cache of the first storage system by monitoring operations on the write-back cache of the first storage system and sending a corresponding command to the second storage system in accord with the monitored operation. Therefore, the method ensures the consistency between the backup data and the data stored in the write-back cache of the first storage system, thereby increasing the security of the data.
摘要:
Organic semiconductor-based devices such as thin film transistors, organic light emitting devices and solar cells have potential in low cost electronic and optoelectronic applications. The performance of these organic semiconductor-based devices is often limited by the large resistance between the organic semiconductors and counter electrodes. This invention provides device structures and methods to reduce the unwanted resistance.
摘要:
A method of programming a phase change device includes selecting a desired threshold voltage (Vth) and applying a programming pulse to a phase change material in the phase change device. The applying of the programming pulse includes applying a quantity of energy to the phase change material to drive at least a portion of this material above a melting energy level. A portion of the energy applied to the phase change material is allowed to dissipate below the melting energy level. The shape of the energy dissipation from the phase change material is controlled until the energy applied to the phase change material is less than a quenched energy level, to cause the phase change device to have the desired Vth. A remaining portion of the energy applied to the phase change material is allowed to dissipate to an environmental level.
摘要:
The present invention discloses an external optical storage device having a dustproof cover comprising an internal optical storage device and an external enclosure. The optical storage device has at least one slot on its panel, and the external enclosure comprises a box body, a front cover, and a dustproof cover. The box body is a structure in the shape of a box and has an interior space for containing and installing the internal optical storage device. The front cover is hollow and disposed at the front panel of the box body, and the dustproof cover is disposed on the front cover at the position in front of the slot. If the internal optical storage device is not in use, the dustproof cover seals the slot and if the internal optical storage device is in use, the dustproof cover can be lifted to expose the slot.
摘要:
The present invention relates generally to the field of anti-infective, anti-proliferative, anti-inflammatory, and prokinetic agents. More particularly, the invention relates to a family of compounds having both a biaryl moiety and at least one heterocylic moiety that are useful as such agents.