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公开(公告)号：US20120281729A1
公开(公告)日：2012-11-08
申请号：US13387075
申请日：2010-01-29
Applicant: Fung Suong Ou , Zhiyong Li , Huei Pei Kuo , Min Hu
Inventor： Fung Suong Ou , Zhiyong Li , Huei Pei Kuo , Min Hu
CPC classification number: B82Y15/00 , G01N21/658 , H01L29/0665
Abstract: An environment sensitive device is disclosed. The device includes a substrate, a three-dimensional structure established on the substrate, a first coating established on a first portion of the three-dimensional structure, and a second coating established on a second portion of the three-dimensional structure. The first and second coatings contain different materials that are configured to respond differently when exposed to a predetermined external stimulus.
Abstract translation: 公开了一种环境敏感设备。 该装置包括衬底，在衬底上建立的三维结构，在三维结构的第一部分上建立的第一涂层和建立在三维结构的第二部分上的第二涂层。 第一和第二涂层包含不同的材料，其被配置成当暴露于预定的外部刺激时不同地响应。
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42.发明申请NANOROD SURFACE ENHANCED RAMAN SPECTROSCOPY APPARATUS, SYSTEM AND METHOD 审中-公开NANOROD表面增强拉曼光谱仪器，系统和方法公开(公告)号：US20120188539A1
公开(公告)日：2012-07-26
申请号：US13014683
申请日：2011-01-26
Applicant: Michael J. Stuke , Shih-Yuan (SY) Wang , Zhiyong Li , Min Hu , Fung Suong Ou , Huei Pei Kuo
Inventor： Michael J. Stuke , Shih-Yuan (SY) Wang , Zhiyong Li , Min Hu , Fung Suong Ou , Huei Pei Kuo
CPC classification number: B82Y20/00 , G01N21/658
Abstract: A nanorod surface enhanced Raman spectroscopy (SERS) apparatus, system and method of SERS using nanorods that are activated with a key. The nanorod SERS apparatus includes a plurality of nanorods, an activator to move the nanorods from an inactive to an active configuration and the key to trigger the activator. The nanorod SERS system further includes a Raman signal detector and an illumination source. The method of SERS using nanorods includes activating a plurality of nanorods with the key, illuminating the activated plurality of nanorods, and detecting a Raman scattering signal when the nanorods are in the active configuration.
Abstract translation: 纳米棒表面增强拉曼光谱（SERS）装置，使用由键激活的纳米棒的SERS的系统和方法。 纳米棒SERS装置包括多个纳米棒，激活剂将纳米棒从非活性构型移动到活性构型，以及触发激活剂的键。 纳米棒SERS系统还包括拉曼信号检测器和照明源。 使用纳米棒的SERS的方法包括用键激活多个纳米棒，照亮激活的多个纳米棒，以及当纳米棒处于活动配置时检测拉曼散射信号。
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公开(公告)号：US20120119315A1
公开(公告)日：2012-05-17
申请号：US13384950
申请日：2010-01-29
Applicant: Fung Suong Ou , Huei Pei Kuo , Zhiyong Li , Min Hu
Inventor： Fung Suong Ou , Huei Pei Kuo , Zhiyong Li , Min Hu
IPC: H01L23/48 , H01L21/28 , H01L31/0224
CPC classification number: G01N21/658 , B82Y15/00 , G01J3/44 , G01N27/12
Abstract: A sensing device (10, 10′) includes a substrate (14), and first and second electrodes (EIC, EICS, EO) established on the substrate (14). The first electrode (EIC, EICS) has a three-dimensional shape, and the second electrode (EO) is electrically isolated from and surrounds a perimeter of the first electrode (EIC, EICS).
Abstract translation: 感测装置（10,10'）包括衬底（14）以及在衬底（14）上建立的第一和第二电极（EIC，EICS，EO）。 第一电极（EIC，EICS）具有三维形状，并且第二电极（EO）与第一电极（EIC，EICS）的周边电隔离并围绕第一电极的周边。
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公开(公告)号：US20120113420A1
公开(公告)日：2012-05-10
申请号：US13384456
申请日：2009-09-17
Applicant: Huei Pei Kuo , Shih-Yuan Wang , Min Hu , Zhiyong Li , Alexander M. Bratkovski
Inventor： Huei Pei Kuo , Shih-Yuan Wang , Min Hu , Zhiyong Li , Alexander M. Bratkovski
IPC: G01J3/44
CPC classification number: G01N21/658 , B82Y15/00 , B82Y30/00
Abstract: An electrically driven device (10) for surface enhanced Raman spectroscopy includes a first electrode (16), a substrate (12) positioned proximate to the first electrode (16), a plurality of cone shaped protrusions (12′) formed integrally with or on a substrate surface (S), a Raman signal-enhancing material (14) coated on each protrusion (12′), and a second electrode (18) positioned relative to the first electrode (16) at a predetermined distance, D. Each of the protrusions (12′) has a tip (22) with a radius of curvature, r, ranging from about 0.1 nm to about 100 nm. The second electrode (18) is positioned relative to the first electrode (16) such that the electrodes (16, 18) together produce an electric field (EF) when a voltage bias is applied therebetween. The electric field (EF) has a field distribution that creates a stronger field gradient at a region proximate to the tips (22) than at other portions of the substrate (12).
Abstract translation: 用于表面增强拉曼光谱的电驱动装置（10）包括第一电极（16），靠近第一电极（16）定位的基板（12），与该第一电极（16）一体形成的多个锥形突起 涂覆在每个突起（12'）上的衬底表面（S），拉曼信号增强材料（14）和相对于第一电极（16）以预定距离D定位的第二电极（D）。 突起（12'）具有从约0.1nm至约100nm范围内的具有曲率半径r的尖端（22）。 第二电极（18）相对于第一电极（16）定位，使得当施加电压时，电极（16,18）一起产生电场（EF）。 电场（EF）具有在靠近尖端（22）的区域处比在衬底（12）的其它部分处产生更强的场梯度的场分布。
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公开(公告)号：US20120107569A1
公开(公告)日：2012-05-03
申请号：US12916239
申请日：2010-10-29
Applicant: Michael Josef Stuke , Zhiyong Li , Shih-Yuan Wang , Fung Suong Ou , Min Hu , Wei Wu , Lars Helge Thylen
Inventor： Michael Josef Stuke , Zhiyong Li , Shih-Yuan Wang , Fung Suong Ou , Min Hu , Wei Wu , Lars Helge Thylen
CPC classification number: G01N21/658 , B81B3/0005 , Y10T428/24355 , Y10T428/24612
Abstract: A device for Surface Enhanced Raman Scattering (SERS). The device includes a plurality of nanostructures protruding from a surface of a substrate, a SERS active metal disposed on a portion of said plurality of nanostructures, and a low friction film disposed over the plurality of nanostructures and the SERS active metal. The low friction film is to prevent adhesion between the plurality of nanostructures.
Abstract translation: 用于表面增强拉曼散射（SERS）的器件。 该装置包括从衬底表面突出的多个纳米结构，设置在所述多个纳米结构的一部分上的SERS活性金属，以及设置在多个纳米结构和SERS活性金属上的低摩擦膜。 低摩擦膜是为了防止多个纳米结构之间的粘附。
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Patent Agency Ranking
46.发明申请SURFACE-ENHANCED RAMAN SPECTROSCOPY DEVICE AND A MOLD FOR CREATING AND A METHOD FOR MAKING THE SAME 有权表面增强的拉曼光谱装置和用于制造的模具及其制造方法公开(公告)号：US20110267606A1
公开(公告)日：2011-11-03
申请号：US12771440
申请日：2010-04-30
Applicant: Fung Suong Ou , Zhiyong Li , Min Hu , Wei Wu
Inventor： Fung Suong Ou , Zhiyong Li , Min Hu , Wei Wu
CPC classification number: G02B1/12 , G01N21/658
Abstract: A surface-enhanced Raman spectroscopy device includes a substrate, and an ultraviolet cured resist disposed on the substrate. The ultraviolet cured resist has a pattern of cone-shaped protrusions, where each cone-shaped protrusion has a tip with a radius of curvature equal to or less than 10 nm. The ultraviolet cured resist is formed of a predetermined ratio of a photoinitiator, a cross-linking agent, and a siloxane based backbone chain. A Raman signal-enhancing material is disposed on each of the cone-shaped protrusions.
Abstract translation: 表面增强拉曼光谱装置包括基板和设置在基板上的紫外线固化抗蚀剂。 紫外线固化抗蚀剂具有锥形突起的图案，其中每个锥形突起具有等于或小于10nm的曲率半径的尖端。 紫外线固化的抗蚀剂由光引发剂，交联剂和基于硅氧烷的主链以预定比例形成。 拉曼信号增强材料设置在每个锥形突起上。
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公开(公告)号：US09548620B2
公开(公告)日：2017-01-17
申请号：US13976605
申请日：2011-12-07
Applicant: Min Hu , Yunfeng Liu , Hai Yang
Inventor： Min Hu , Yunfeng Liu , Hai Yang
CPC classification number: H02J7/0068 , C02F1/4604 , C02F1/4691 , C02F2201/46135 , C02F2201/4616 , C02F2303/10 , H02M3/1584 , H02M2001/007 , Y02W10/30
Abstract: A system comprising a plurality of stacks and a plurality of converters, each of the plurality of converters is operable to charge a corresponding stack for adsorbing ions in a liquid, wherein when one of the plurality of stacks is charged or discharged at a first state, one of the plurality of converters associating with the stack operates in a first mode, and is configured to indirectly convert a first voltage to a second voltage at least by an intermediate stage, one of the plurality of stacks is charged or discharged at a second state, one of the plurality of converters associating with the stack operates in a second mode, and is configured to directly convert the first voltage to the second voltage.
Abstract translation: 一种包括多个堆叠和多个转换器的系统，所述多个转换器中的每一个可操作用于对相应的堆叠进行充电以吸附液体中的离子，其中当所述多个堆叠中的一个在第一状态下被充电或排出时， 与堆叠相关联的多个转换器中的一个转换器以第一模式运行，并且被配置为至少在中间级间隔地将第一电压间接地转换为第二电压，多个堆叠中的一个在第二状态下被充电或放电 与堆叠相关联的多个转换器中的一个在第二模式下工作，并被配置为将第一电压直接转换为第二电压。
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公开(公告)号：US09063126B2
公开(公告)日：2015-06-23
申请号：US12568085
申请日：2009-09-28
Applicant: Michael R. Schrimpf , Chih-Hung Lee , Tao Li , Gregory A. Gfesser , Kathleen H. Mortell , Ramin Faghih , Diana L. Nersesian , Kevin B. Sippy , William H. Bunnelle , Marc Scanio , Lei Shi , Murali Gopalakrishnan , Diana L. Donnelly-Roberts , Min Hu
Inventor： Michael R. Schrimpf , Chih-Hung Lee , Tao Li , Gregory A. Gfesser , Kathleen H. Mortell , Ramin Faghih , Diana L. Nersesian , Kevin B. Sippy , William H. Bunnelle , Marc Scanio , Lei Shi , Murali Gopalakrishnan , Diana L. Donnelly-Roberts , Min Hu
IPC: A61K31/439 , C07D471/08 , G01N33/50 , C07D471/18 , C07D487/10 , C07D487/18 , G01N33/68
CPC classification number: G01N33/5058 , C07D471/18 , C07D487/10 , C07D487/18 , G01N33/6896 , G01N2800/28 , G01N2800/30
Abstract: The present application relates to indole and indoline derivatives of formula (I), (II), (III), (IV), (V), or (VI) wherein a, R1, R2, R3, R4, R5, U, V, W, X, Y, and Z are as defined in the specification. The present application also relates to compositions comprising such compounds, and methods of treating disease conditions using such compounds and compositions, and methods for identifying such compounds.
Abstract translation: 本申请涉及式（I），（II），（III），（IV），（V）或（VI）的吲哚和二氢吲哚衍生物，其中a，R1，R2，R3，R4，R5， V，W，X，Y和Z如说明书中所定义。 本申请还涉及包含这些化合物的组合物，以及使用这些化合物和组合物治疗疾病状况的方法，以及鉴定这些化合物的方法。
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公开(公告)号：US20130270116A1
公开(公告)日：2013-10-17
申请号：US13976605
申请日：2011-12-07
Applicant: Min Hu , Yunfeng Liu , Hai Yang
Inventor： Min Hu , Yunfeng Liu , Hai Yang
CPC classification number: H02J7/0068 , C02F1/4604 , C02F1/4691 , C02F2201/46135 , C02F2201/4616 , C02F2303/10 , H02M3/1584 , H02M2001/007 , Y02W10/30
Abstract: A system comprising a plurality of stacks and a plurality of converters, each of the plurality of converters is operable to charge a corresponding stack for adsorbing ions in a liquid, wherein when one of the plurality of stacks is charged or discharged at a first state, one of the plurality of converters associating with the stack operates in a first mode, and is configured to indirectly convert a first voltage to a second voltage at least by an intermediate stage, one of the plurality of stacks is charged or discharged at a second state, one of the plurality of converters associating with the stack operates in a second mode, and is configured to directly convert the first voltage to the second voltage.
Abstract translation: 一种包括多个堆叠和多个转换器的系统，所述多个转换器中的每一个可操作用于对相应的堆叠进行充电以吸附液体中的离子，其中当所述多个堆叠中的一个在第一状态下被充电或排出时， 与堆叠相关联的多个转换器中的一个转换器以第一模式运行，并且被配置为至少在中间级间隔地将第一电压间接地转换为第二电压，多个堆叠中的一个在第二状态下被充电或放电 与堆叠相关联的多个转换器中的一个在第二模式下工作，并被配置为将第一电压直接转换为第二电压。
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公开(公告)号：US20090280478A1
公开(公告)日：2009-11-12
申请号：US11915645
申请日：2006-05-30
Applicant: Kornelia Polyak , Min Hu , Noga Qimron , Jun Yao
Inventor： Kornelia Polyak , Min Hu , Noga Qimron , Jun Yao
CPC classification number: C12N15/1093 , C12Q1/6855 , C12Q1/6881 , C12Q2600/154 , C12Q2600/158 , C12Q2521/331
Abstract: The invention provides a method of analyzing the methylation status of all or part of an entire genome. Moreover, the invention features methods of and reagents for characterizing biological cells containing DNA that is susceptible to methylation. Such methods include methods of diagnosing cancer, e.g., breast cancer.
Abstract translation: 本发明提供了分析全部或部分整个基因组的甲基化状态的方法。 此外，本发明的特征在于含有易于甲基化的DNA的生物细胞的表征方法和试剂。 这些方法包括诊断癌症的方法，例如乳腺癌。
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