公开(公告)号：US20160228013A1

公开(公告)日：2016-08-11

申请号：US15022874

申请日：2014-10-07

申请人： CEDARS-SINAI MEDICAL CENTER

发明人： Hasanian Al-Jilaihawi ,  Rajendra Makkar

IPC分类号： A61B5/0215 ,  A61B5/0402 ,  A61B5/00

CPC分类号： A61B5/0215 ,  A61B5/0004 ,  A61B5/02156 ,  A61B5/02158 ,  A61B5/0402 ,  A61B5/6851 ,  A61B5/6852 ,  A61B5/6857 ,  A61B5/742 ,  A61B2560/0223

摘要： Described herein is a guide wire that includes one, two or multiple pressure transducers for use in TAVI. The guide wire may include an aortic pressure sensor spaced from a left ventricular pressure sensor with sufficient length to allow the aortic pressure sensor to be located in the aorta while the ventricular pressure sensor is simultaneously located in the left ventricle. The pressure readings between the left ventricle and aorta may be subtracted to determine an improved indication of the prognosis of a patient with intermediate post-TAVR aortic regurgitation after assessment with transesophageal echocardiography.

摘要翻译： 这里描述的是一种导丝，其包括用于TAVI的一个，两个或多个压力换能器。 引导线可以包括与左心室压力传感器间隔开的足够长度的主动脉压力传感器，以允许主动脉压力传感器位于主动脉中，同时心室压力传感器同时位于左心室中。 可以减去左心室和主动脉之间的压力读数，以确定经经食管超声心动图评估后TAVR中度后主动脉瓣反流的患者预后的改善指标。

公开(公告)号：US20160073884A1

公开(公告)日：2016-03-17

申请号：US14950847

申请日：2015-11-24

申请人： ST. JUDE MEDICAL COORDINATION CENTER BVBA

发明人： Magnus SAMUELSSON ,  Sauli TULKKI

IPC分类号： A61B5/00 ,  A61B6/00 ,  A61B5/026 ,  A61B5/0205 ,  A61B5/06 ,  A61B5/0215

CPC分类号： A61B5/00 ,  A61B5/0031 ,  A61B5/0084 ,  A61B5/02 ,  A61B5/02055 ,  A61B5/0215 ,  A61B5/02156 ,  A61B5/026 ,  A61B5/06 ,  A61B5/062 ,  A61B5/065 ,  A61B5/14503 ,  A61B5/1495 ,  A61B5/6851 ,  A61B5/6852 ,  A61B6/00 ,  A61B6/12 ,  A61B34/20 ,  A61B2034/2055 ,  A61B2562/085 ,  G08C17/02 ,  G08C19/16 ,  H04B1/713

摘要： A measurement system may comprise a sensor wire and a transceiver unit. The sensor wire may comprise an insertable portion configured to be inserted in a blood vessel of a patient's body and a sensor disposed within the insertable portion at a distal end of the sensor wire. The sensor is configured to measure a parameter when inserted inside the patient. The transceiver unit may comprise: a housing adapted to be connected to a proximal end of the sensor wire; and a first communication module within the housing adapted to wirelessly communicate by a communication signal with an external second communication module in order to transfer information to the external second communication module.

公开(公告)号：US20140187985A1

公开(公告)日：2014-07-03

申请号：US14140134

申请日：2013-12-24

申请人： Volcano Corporation

发明人： Paul Douglas Corl ,  David H. Burkett ,  Douglas E. Meyer

IPC分类号： A61B5/0215

CPC分类号： A61B5/02156 ,  A61B2560/0252 ,  A61B2562/226

摘要： Intravascular devices, systems, and methods are disclosed. In some embodiments, the intravascular devices include at least one pressure sensing component within a distal portion of the device. In that regard, one or more electrical, electronic, optical, and/or electro-optical pressure-sensing components is secured to an elongated member and the system includes components to process the output signals according to various calibration parameters.

摘要翻译： 公开了血管内装置，系统和方法。 在一些实施例中，血管内装置包括在装置的远端部分内的至少一个压力感测部件。 在这方面，一个或多个电气，电子，光学和/或电光学压力感测组件固定到细长构件，并且系统包括根据各种校准参数来处理输出信号的组件。

公开(公告)号：US20130229287A1

公开(公告)日：2013-09-05

申请号：US13847226

申请日：2013-03-19

申请人： ST. JUDE MEDICAL SYSTEMS AB

发明人： Magnus SAMUELSSON ,  Sauli TULKKI

IPC分类号： G08C19/16

CPC分类号： A61B5/00 ,  A61B5/0031 ,  A61B5/0084 ,  A61B5/02 ,  A61B5/02055 ,  A61B5/0215 ,  A61B5/02156 ,  A61B5/026 ,  A61B5/06 ,  A61B5/062 ,  A61B5/065 ,  A61B5/14503 ,  A61B5/1495 ,  A61B5/6851 ,  A61B5/6852 ,  A61B6/00 ,  A61B6/12 ,  A61B34/20 ,  A61B2034/2055 ,  A61B2562/085 ,  G08C17/02 ,  G08C19/16 ,  H04B1/713

摘要： A measurement system may comprise a sensor wire and a transceiver unit. The sensor wire may comprise an insertable portion configured to be inserted in a blood vessel of a patient's body and a sensor disposed within the insertable portion at a distal end of the sensor wire. The sensor is configured to measure a parameter when inserted inside the patient. The transceiver unit may comprise: a housing adapted to be connected to a proximal end of the sensor wire; and a first communication module within the housing adapted to wirelessly communicate by a communication signal with an external second communication module in order to transfer information to the external second communication module.

摘要翻译： 测量系统可以包括传感器线和收发器单元。 传感器线可以包括被配置为插入患者身体的血管中的可插入部分和设置在传感器线的远端处的可插入部分内的传感器。 传感器被配置为在插入患者体内时测量参数。 收发器单元可以包括：适于连接到传感器线的近端的壳体; 以及壳体内的第一通信模块，适于通过通信信号与外部第二通信模块进行无线通信，以将信息传送到外部第二通信模块。

公开(公告)号：US08504152B2

公开(公告)日：2013-08-06

申请号：US11779350

申请日：2007-07-18

申请人： Brian Jeffrey Wenzel ,  Dan E. Gutfinger ,  Mihir Naware ,  Xiaoyi Min ,  Jeffery Siou ,  Anders Bjorling ,  Dorin Panescu

发明人： Brian Jeffrey Wenzel ,  Dan E. Gutfinger ,  Mihir Naware ,  Xiaoyi Min ,  Jeffery Siou ,  Anders Bjorling ,  Dorin Panescu

IPC分类号： A61N1/365

CPC分类号： A61B5/02156 ,  A61B5/0215 ,  A61B5/72 ,  A61N1/365 ,  A61N1/36564 ,  A61N1/36578 ,  A61N1/3682 ,  A61N1/3684 ,  A61N1/37258

摘要： Techniques are provided for estimating left atrial pressure (LAP) or other cardiac performance parameters based on measured conduction delays. In particular, LAP is estimated based interventricular conduction delays. Predetermined conversion factors stored within the device are used to convert the various the conduction delays into LAP values or other appropriate cardiac performance parameters. The conversion factors may be, for example, slope and baseline values derived during an initial calibration procedure performed by an external system, such as an external programmer. In some examples, the slope and baseline values may be periodically re-calibrated by the implantable device itself. Techniques are also described for adaptively adjusting pacing parameters based on estimated LAP or other cardiac performance parameters. Still further, techniques are described for estimating conduction delays based on impedance or admittance values and for tracking heart failure therefrom.

公开(公告)号：US08068907B2

公开(公告)日：2011-11-29

申请号：US11842133

申请日：2007-08-20

申请人： Brian Mann ,  James S. Whiting ,  Neal L. Eigler

发明人： Brian Mann ,  James S. Whiting ,  Neal L. Eigler

IPC分类号： A61B5/05

CPC分类号： A61B5/02156 ,  A61B5/0215 ,  A61B5/042 ,  A61B5/0452 ,  A61B5/7267 ,  A61B8/04 ,  A61B2560/0223 ,  A61N1/36521 ,  A61N1/36564

摘要： A method of monitoring pressure within a medical patient, includes measuring an actual pressure in a medical patient in a first time period; measuring an indicator of the actual pressure in the first time period, wherein the indicator is derived from an electrical signal of the patient's heart; determining a correlative relationship between the actual pressure and the indicator, wherein both the actual pressure and the indicator are obtained in the first time period; measuring the indicator in a second time period; and determining the actual pressure in the second time period based on the correlative relationship obtained in the first time period and the indicator obtained in the second time period.

摘要翻译： 一种监测医疗患者内的压力的方法，包括在第一时间段内测量医疗患者的实际压力; 测量所述第一时间段中的实际压力的指示器，其中所述指示符是根据患者心脏的电信号导出的; 确定实际压力和指标之间的相关关系，其中在第一时间段中获得实际压力和指标; 在第二时间段内测量指标; 并且基于在第一时间段中获得的相关关系和在第二时间段中获得的指标来确定第二时间段中的实际压力。

公开(公告)号：US08038623B2

公开(公告)日：2011-10-18

申请号：US12661840

申请日：2010-03-25

申请人： Jonathan Williams ,  Shrenik Daftary ,  Boris Leschinsky

发明人： Jonathan Williams ,  Shrenik Daftary ,  Boris Leschinsky

IPC分类号： A61B5/02

CPC分类号： A61B5/02156 ,  A61M25/10185 ,  A61M2025/0002

摘要： A method for performing an in-vivo calibration of a blood pressure sensor that is associated with an in-vivo balloon system. The method involves monitoring a patient's blood pressure by observing the system gas pressure while at the same time monitoring the patient's blood pressure through the sensor. The blood pressure measurements obtained by monitoring the system gas pressure are used as reference, or “true,” blood pressure measurements, and an “offset” is determined between the reference blood pressure measurements and the blood pressure measurements obtained through the sensor. The offset can be stored in a memory, which may also store sensor sensitivity data. The offset and/or sensitivity data may be used to adjust future measurements obtained from the sensor, thereby generating calibrated sensor measurements.

摘要翻译： 一种用于进行与体内气球系统相关联的血压传感器的体内校准的方法。 该方法包括通过观察系统气体压力来监测患者的血压，同时通过传感器监测患者的血压。 通过监测系统气体压力获得的血压测量用作参考或“真实”血压测量，并且在参考血压测量值与通过传感器获得的血压测量值之间确定“偏移”。 偏移量可以存储在存储器中，这也可以存储传感器灵敏度数据。 偏移和/或灵敏度数据可用于调整从传感器获得的未来测量值，从而生成经校准的传感器测量值。

公开(公告)号：US07771362B2

公开(公告)日：2010-08-10

申请号：US11494973

申请日：2006-07-27

申请人： Jonathan Williams ,  Shrenik Daftary ,  Robert Hamilton

发明人： Jonathan Williams ,  Shrenik Daftary ,  Robert Hamilton

IPC分类号： A61B5/02

CPC分类号： A61B5/02156

摘要： A method for performing an in-vivo calibration of a blood pressure sensor that is associated with a balloon of an in-vivo balloon system, the sensor and balloon being associated such that the sensor is in-vivo when the balloon is in-vivo. The balloon is inflated so that a gas pressure in the balloon system is indicative of a patient's blood pressure. The patient's blood pressure is monitored through two channels, the gas pressure and the sensor. The blood pressure measurements obtained by monitoring the gas pressure are used as reference, or “true,” blood pressure measurements to determine a mathematical relationship between blood pressure measurements obtained through the sensor and the reference blood pressure measurements. In this manner, future blood pressure measurements obtained through the sensor can be modified according to the mathematical relationship to generate calibrated blood pressure measurements.

摘要翻译： 一种用于执行与体内气球系统的球囊相关联的血压传感器的体内校准的方法，所述传感器和球囊相关联，使得当所述气囊在体内时所述传感器处于体内。 气囊被充气，使得气囊系统中的气体压力表示患者的血压。 通过两个通道监测患者的血压，气压和传感器。 通过监测气体压力获得的血压测量用作参考或“真实”血压测量，以确定通过传感器获得的血压测量与参考血压测量之间的数学关系。 以这种方式，通过传感器获得的未来血压测量可以根据数学关系进行修改以产生校准的血压测量值。

公开(公告)号：US20090105598A1

公开(公告)日：2009-04-23

申请号：US11975055

申请日：2007-10-17

申请人： Jonathan Williams ,  Shrenik Daftary ,  Boris Leschinsky

发明人： Jonathan Williams ,  Shrenik Daftary ,  Boris Leschinsky

IPC分类号： A61B5/02

CPC分类号： A61B5/02156 ,  A61M25/10185 ,  A61M2025/0002

摘要： A method for performing an in-vivo calibration of a blood pressure sensor that is associated with an in-vivo balloon system. The method involves monitoring a patient's blood pressure by observing the system gas pressure while at the same time monitoring the patient's blood pressure through the sensor. The blood pressure measurements obtained by monitoring the system gas pressure are used as reference, or “true,” blood pressure measurements, and an “offset” is determined between the reference blood pressure measurements and the blood pressure measurements obtained through the sensor. The offset can be stored in a memory, which may also store sensor sensitivity data. The offset and/or sensitivity data may be used to adjust future measurements obtained from the sensor, thereby generating calibrated sensor measurements.

摘要翻译： 一种用于进行与体内气球系统相关联的血压传感器的体内校准的方法。 该方法包括通过观察系统气体压力来监测患者的血压，同时通过传感器监测患者的血压。 通过监测系统气体压力获得的血压测量用作参考或“真实”血压测量，并且在参考血压测量值与通过传感器获得的血压测量值之间确定“偏移”。 偏移量可以存储在存储器中，这也可以存储传感器灵敏度数据。 偏移和/或灵敏度数据可用于调整从传感器获得的未来测量值，从而生成经校准的传感器测量值。

公开(公告)号：US20080312553A1

公开(公告)日：2008-12-18

申请号：US12125700

申请日：2008-05-22

申请人： Michael J. Timmons

发明人： Michael J. Timmons

IPC分类号： A61B5/03

CPC分类号： A61N1/36564 ,  A61B5/02156 ,  A61B5/02158 ,  A61B2560/0242 ,  A61B2560/0257

摘要： The invention relates to devices, systems, and methods for the measurement of a pressure within a body that is adjusted to compensate for variations in local atmospheric pressure. A pressure measurement system can include an implantable target pressure sensor, an implantable internal reference pressure sensor located remotely from the target pressure sensor, an external reference pressure sensor configured to transmit a telemetric signal that is indicative of the local atmospheric pressure, and at least one condition indicator. The implantable medical device system further includes a controller configured to determine a correlation factor based on a signal from the implantable reference pressure sensor and the signal from the external reference pressure sensor.

摘要翻译： 本发明涉及用于测量体内压力的装置，系统和方法，其被调节以补偿局部大气压力的变化。 压力测量系统可以包括可植入的目标压力传感器，远离目标压力传感器的可植入的内部参考压力传感器，被配置为传送指示局部大气压力的遥测信号的外部参考压力传感器，以及至少一个 条件指示器 可植入医疗装置系统还包括控制器，其被配置为基于来自可植入参考压力传感器的信号和来自外部参考压力传感器的信号来确定相关系数。