Apparatus and method of reacting polymers by exposure to UV radiation to produce injectable medical devices
    44.
    发明授权
    Apparatus and method of reacting polymers by exposure to UV radiation to produce injectable medical devices 有权
    通过暴露于UV辐射使聚合物反应以产生可注射的医疗装置的装置和方法

    公开(公告)号:US09375699B2

    公开(公告)日:2016-06-28

    申请号:US13202345

    申请日:2010-02-22

    Inventor: Sébastien Ladet

    Abstract: Cross-linked compositions include a first precursor functionalized with a first reactive member and a second precursor functionalized with a second reactive member, the first and second reactive members covalently bonding with each other when exposed to UV radiation. The compositions are useful in a variety of surgical and wound treatment applications.

    Abstract translation: 交联组合物包括用第一反应性成员官能化的第一前体和用第二反应性成员官能化的第二前体,当暴露于UV辐射时,第一和第二反应性成员彼此共价键合。 该组合物可用于各种手术和伤口治疗应用。

    REVERSE-PHASE POLYMERISATION PROCESS
    45.
    发明申请

    公开(公告)号:US20160159939A1

    公开(公告)日:2016-06-09

    申请号:US14908872

    申请日:2014-07-29

    Applicant: BASF SE

    Abstract: A reverse-phase suspension polymerisation process for the manufacture of polymer beads comprising forming aqueous monomer beads comprising an aqueous solution of water-soluble ethylenically unsaturated monomer or monomer blend and polymerising the monomer or monomer blend, to form polymer beads while suspended in a non-aqueous liquid, and recovering polymer beads, in which the process comprises providing in a vessel (1) a volume (2) of non-aqueous liquid wherein the volume of non-aqueous liquid extends between at least one polymer bead discharge point (3) and at least one monomer feed point (4), feeding the aqueous monomer or monomer blend through orifices (5) into, or onto, the non-aqueous liquid to form aqueous monomer beads, allowing the aqueous monomer beads to flow towards the polymer bead discharge point initiating polymerisation of the aqueous monomer beads to form polymerising beads, wherein the polymerising beads form polymer beads when they reach the polymer bead discharge point, removing a suspension of the polymer beads in non-aqueous liquid from the vessel at the polymer bead discharge point and recovering, water soluble or water swellable polymer beads from the suspension, in which the aqueous monomer or monomer blend and/or the orifices is/are vibrated such that the frequency multiplied by the weight average droplet diameter is between 150 and 800 mm/s. The invention also relates to the apparatus suitable for carrying out a reverse-phase suspension polymerisation and polymer beads obtainable by the process or employing the apparatus. Furthermore, the invention also relates to polymer beads having a weight mean particle size in the range of 0.05 to 5 mm which are held in a container in an amount of at least 300 kg having a standard deviation of particle size less than 20%. In addition, the invention also provides polymer beads having a weight mean particle size in the range 0.05 to 5 mm having a standard deviation of particle size less than 20% and having an amount of residual acrylamide of less than 500 ppm.

    Polymers Carrying Hydroxyl Groups And Ester Groups And Method For The Production Thereof
    46.
    发明申请
    Polymers Carrying Hydroxyl Groups And Ester Groups And Method For The Production Thereof 有权
    聚合物携带羟基和酯基及其制备方法

    公开(公告)号:US20140200312A1

    公开(公告)日:2014-07-17

    申请号:US13977326

    申请日:2011-12-08

    Abstract: The invention relates to polymers carrying ester/hydroxyl groups, containing repetitive structural units of formulae (I) and (II) in a block-wise, alternating or statistical sequence, wherein D represents a direct bond between the polymer backbone and the hydroxyl group, a C1- to C6-alkene group, a C5- to C12-arylene group, an oxyalkene group of formula —O—R2—, an ester group of formula —C(O)—O—R2— or an amide group of formula —C(O)—N(R3)R2—, E represents a hydrocarbon group having 1 to 50 C-atoms, R2 represents a C2- to C10-alkene group, R3 represents hydrogen or a C1- to C10-alkyl group, which can carry substituents, k represents a number between 1 and 1000, n represents a number from 0 to 4999, m represents a number from 1 to 5000, and n+m represents a number between 10 to 5000, under the proviso that a) the molar portion of the structural units (I); on the polymer is between 0 and 99.9 mol-%, and b) the molar portion of the structural units (II) on the polymer is between 0.1 and 100 mol-% of the repetitive units. The invention also relates to a method for the production of said polymers using microwaves.

    Abstract translation: 本发明涉及含有分子式(I)和(II)的重复结构单元的酯/羟基的聚合物,其中D表示聚合物主链和羟基之间的直接键, C 1〜C 6烯基,C 5〜C 12亚芳基,式-O-R 2 - 的氧化烯基,式-C(O)-O-R 2 - 的酯基或式 -C(O)-N(R 3)R 2 - ,E表示1〜50个碳原子的烃基,R 2表示C 2〜C 10烯基,R 3表示氢或C 1至C 10烷基, 其可以携带取代基,k表示1至1000之间的数字,n表示0至4999的数,m表示1至5000的数,n + m表示10至5000之间的数字,条件是a) 结构单元(I)的摩尔部分; 在聚合物上的摩尔份数在0至99.9mol%之间,b)聚合物上的结构单元(II)的摩尔份数为重复单元的0.1至100mol%。 本发明还涉及使用微波生产所述聚合物的方法。

    Continuous Process For Esterifying Polymers Bearing Acid Groups
    47.
    发明申请
    Continuous Process For Esterifying Polymers Bearing Acid Groups 审中-公开
    用于酯化聚合物的酸性基团的连续方法

    公开(公告)号:US20130274368A1

    公开(公告)日:2013-10-17

    申请号:US13977346

    申请日:2011-12-08

    Abstract: The invention accordingly provides a continuous process for reacting synthetic poly(carboxylic acid)s (A) containing, per polymer chain, at least 10 structural repeat units of formula (I) where R1 is hydrogen, a C1- to C4-alkyl group or a group of formula —COOH, R2 is hydrogen or a C1- to C4-alkyl group, and R3 is hydrogen, a C1- to C4-alkyl group or —COOH, with alcohols (B) of general formula (II) R4—(OH)n  (II) where R4 is a hydrocarbyl radical of 1 to 100 carbon atoms which may be substituted or which may contain hetero atoms, and n is a number from 1 to 10 by a reaction mixture containing at least one synthetic poly(carboxylic acid) (A) and at least one alcohol of formula (II) in a solvent mixture containing water and, based on the weight of the solvent mixture, 0.1-75% by weight of at least one water-miscible organic solvent, and wherein the organic solvent has a dielectric constant of at least 10 when measured at 25° C., being introduced into a reaction sector and on flowing through the reaction sector being exposed to microwave radiation, and wherein the reaction mixture in the reaction sector is heated by the microwave irradiation to temperatures above 100° C.

    Abstract translation: 因此,本发明提供了使包含每个聚合物链的合成聚(羧酸)(A)至少10个结构式(I)重复单元的反应的连续方法,其中R 1是氢,C 1至C 4烷基或 式-COOH的基团,R 2是氢或C 1至C 4烷基,R 3是氢,C 1至C 4烷基或-COOH,与通式(II)的醇(B) (OH)n(II)其中R 4是可以被取代或可以含有杂原子的1至100个碳原子的烃基,n是通过含有至少一个合成聚( 羧酸)(A)和至少一种式(II)的醇在含水的溶剂混合物中,并且基于溶剂混合物的重量,0.1-75重量%的至少一种水混溶性有机溶剂,和 其中当在25℃下测量时,有机溶剂的介电常数至少为10,被引入反应部分和流动 反应部分暴露于微波辐射,并且其中将反应部分中的反应混合物通过微波照射加热至高于100℃的温度。

    Ultrasonic and microwave methods for enhancing the rate of a chemical reaction and apparatus for such methods
    50.
    发明授权
    Ultrasonic and microwave methods for enhancing the rate of a chemical reaction and apparatus for such methods 有权
    用于提高化学反应速率的超声波和微波方法以及用于这种方法的装置

    公开(公告)号:US08052848B2

    公开(公告)日:2011-11-08

    申请号:US12146932

    申请日:2008-06-26

    Inventor: Matthew M. Kropf

    Abstract: The invention relates generally to chemical reactions and processes, and in particular to a method for enhancing the rate of a chemical reaction and to apparatus for carrying out the method. The invention more particularly relates to methods and apparatus which utilize microwave and ultrasonic energy to enhance chemical reaction rates; and in specific instances, the invention relates to methods, processes and apparatus for the synthesis of biodiesel fuels. The methods, processes and apparatus of the invention are useful for the synthesis of biodiesel fuels; and also useful for production of reaction products of esterification and/or transesterification reactions including fatty acid alkyl esters.

    Abstract translation: 本发明一般涉及化学反应和方法,特别涉及提高化学反应速率的方法以及用于实施该方法的装置。 本发明更具体涉及利用微波和超声波能量来提高化学反应速率的方法和装置; 并且在具体情况下,本发明涉及用于合成生物柴油燃料的方法,方法和装置。 本发明的方法,方法和装置可用于合成生物柴油燃料; 并且还可用于生产包括脂肪酸烷基酯在内的酯化和/或酯交换反应的反应产物。

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