公开(公告)号：US11806688B2

公开(公告)日：2023-11-07

申请号：US17449061

申请日：2021-09-27

Applicant: CSBio Instrumentation Co.

Inventor： Dario Slavazza ,  Yoheng Chang ,  David Lippoth

IPC: B01J4/02 ,  G01F11/28 ,  G01F11/42 ,  B01J19/24 ,  C07K1/04 ,  B01D29/03 ,  B01D29/56 ,  B01J19/00

CPC classification number: B01J19/242 ,  B01D29/03 ,  B01D29/56 ,  B01J4/02 ,  B01J19/0046 ,  C07K1/045 ,  G01F11/28 ,  G01F11/42 ,  B01J2219/0004 ,  B01J2219/00286 ,  B01J2219/00346 ,  B01J2219/00389 ,  B01J2219/00418 ,  B01J2219/00423 ,  B01J2219/00495 ,  B01J2219/00725

Abstract: A peptide synthesis instrument can be used for small scale peptide synthesis. The instrument can include several unique features, including a compression style reaction vessel permitting quick setup of the reaction vessel, a double reaction vessel system permitting efficient mixing without loss of solvent or solvent-to-resin contact, gravity-fed heated reservoirs establishing a fixed volume for delivery to the reaction vessel, fume-free solvent addition permitting solvent addition to fixed bottles, and an improved amino acid manifold assembly which reduces the number of components and increases the ease of use of the instrument. Each of these features improve upon the current state of the art in solid phase automated peptide synthesizers.

公开(公告)号：US20230233479A1

公开(公告)日：2023-07-27

申请号：US18152394

申请日：2023-01-10

Applicant: Purdue Research Foundation

Inventor： Arun V. GIRIDHAR ,  Michael HARRIS ,  Gintaras V. REKLAITIS ,  Lynne S. TAYLOR ,  Zoltan K. NAGY ,  Elcin ICTEN ,  Frederick FIESSER ,  Laura HIRSHFIELD

IPC: A61K9/70 ,  A61K47/10 ,  A61K31/415 ,  A61K31/167 ,  A61K31/192 ,  A61K31/196 ,  A61K31/635 ,  A61K47/14 ,  A61K47/34 ,  A61K47/38 ,  B01J4/00 ,  B01J4/02

CPC classification number: A61K9/7007 ,  A61K31/167 ,  A61K31/192 ,  A61K31/196 ,  A61K31/415 ,  A61K31/635 ,  A61K47/10 ,  A61K47/14 ,  A61K47/34 ,  A61K47/38 ,  B01J4/002 ,  B01J4/02 ,  B01J4/008 ,  B01J2204/005 ,  B01J2204/007

Abstract: Systems and methods for delivering active ingredients, such as pharmaceutically active ingredients, to substrates are described herein. The active ingredients are delivered as fluids to a fluiddispensing device for the creation of one or more drops for deposition onto substrates such as for the creation of microdoses. The invention further includes microdoses made by such processes.

公开(公告)号：US11667515B2

公开(公告)日：2023-06-06

申请号：US16618813

申请日：2017-08-17

Applicant: KURITA WATER INDUSTRIES LTD.

Inventor： Yuuya Sasaki

IPC: B67D7/74 ,  B01J4/00 ,  B67D7/36 ,  B67D7/70 ,  C11D7/04 ,  C11D7/50 ,  B67D7/02 ,  B01J4/02 ,  H01L21/02

CPC classification number: B67D7/743 ,  B01J4/00 ,  B01J4/001 ,  B67D7/0227 ,  B67D7/36 ,  B67D7/70 ,  C11D7/04 ,  C11D7/50 ,  B01J4/008 ,  B01J4/02 ,  H01L21/02041

Abstract: A chemical solution supply part for supplementing the chemical solution to the chemical solution storage tank and a purge gas supply part for supplying N2 gas as a purge gas to the chemical solution storage tank are in communication with the chemical solution storage tank, and a first manometer serving as a pressure measurement part is arranged on the chemical solution storage tank. In addition, a drain piping is connected to a head portion of the plunger pump, and an automatically controlled air-bleed valve, which is an air-bleed mechanism, is arranged on the drain piping. On the other hand, a second manometer is arranged in the middle of the chemical solution supply pipe, and a front end of the solution supply pipe on the downstream side serves as an injection point for the chemical solution S.

公开(公告)号：US20180353634A1

公开(公告)日：2018-12-13

申请号：US16061733

申请日：2016-12-08

Applicant: SHINVA MEDICAL INSTRUMENT CO., LTD.

Inventor： Haijun ZHANG ,  Qinghai ZHAO ,  Jianglong YU ,  Tomomasa ITARASHIKI ,  Daiki ANRAKU

IPC: A61L2/26 ,  A61L2/18

CPC classification number: A61L2/26 ,  A61L2/18 ,  A61L2/20 ,  B01J4/001 ,  B01J4/002 ,  B01J4/007 ,  B01J4/02

Abstract: Provided is a system for supplying a liquid (such as an irritant chemical solution) safely. This liquid supplying system comprises: a base on which a container containing liquid is placed; a hollow needle having a spired part; a first movement mechanism that moves the needle between a first needle position at which the spired part is separated from the container and a second needle position at which the spired part is passed through a wall of the container; a hollow tube having a smaller outer diameter than the inner diameter of the lumen of the needle; and a second movement mechanism that moves the tube between a first tube position separated from the container and a second tube position at which the tube is passed through the lumen of the needle located at the second needle position and is inserted inside the container.

公开(公告)号：US20180244512A1

公开(公告)日：2018-08-30

申请号：US15903530

申请日：2018-02-23

Applicant: Joseph Maynard Capra

Inventor： Joseph Maynard Capra

IPC: B67D7/22 ,  B67D7/36 ,  B67D7/08

CPC classification number: B67D7/222 ,  B01J4/008 ,  B01J4/02 ,  B67D7/085 ,  B67D7/362 ,  B67D7/46 ,  F16K11/0873 ,  F16K21/06 ,  F16K31/535 ,  F16K31/602

Abstract: A mechanical system for calibration during a chemical feed process includes a ball valve that includes three openings. The ball valve is in communication with a lever, which when turned to a fill position, allows the filling of a drawdown cylinder for calibration. The ball valve automatically returns to its original default position within about a minute with a spring force automatically pushing it back to its start position.

公开(公告)号：US09950317B2

公开(公告)日：2018-04-24

申请号：US14726892

申请日：2015-06-01

Applicant: KOREA INSTITUTE OF ENERGY RESEARCH

Inventor： Hee-Yeon Kim ,  Guk-Hyeon Kwon

IPC: B01J12/02 ,  B01J19/06 ,  B01J37/02 ,  B01J19/24 ,  B01J19/02 ,  B01J4/02

CPC classification number: B01J37/0225 ,  B01J4/02 ,  B01J12/02 ,  B01J19/02 ,  B01J19/06 ,  B01J19/24 ,  B01J2204/002 ,  B01J2204/007 ,  B01J2219/00105 ,  B01J2219/0254 ,  B01J2219/0277 ,  B01J2219/0286 ,  B01J2219/1946

Abstract: Disclosed are a large-scale composite synthesis system, a reactor therefor, and a synthesis method using the same, wherein two or more different samples are vaporized in respective vaporizers, and are then fed into a reactor that has a relatively large transverse cross-sectional diameter compared to the connector for transporting the samples in a gas phase and is maintained at a temperature lower than that of the connector, thus producing a powder composite, the composite being synthesized while being electrostatically attached to an adherend surface.

公开(公告)号：US09938247B2

公开(公告)日：2018-04-10

申请号：US15118394

申请日：2015-01-30

Applicant: Casale SA

Inventor： Enrico Rizzi

IPC: C07D251/62 ,  C07D251/60 ,  B01J19/24 ,  B01J4/02 ,  B01J3/04 ,  B01J10/00

CPC classification number: C07D251/60 ,  B01J3/04 ,  B01J4/02 ,  B01J10/00 ,  B01J10/005 ,  B01J19/246 ,  B01J2219/00078 ,  B01J2219/00081 ,  B01J2219/24 ,  C07D251/62

Abstract: A reactor and associated process for the high-pressure synthesis of melamine from urea, comprising a primary step of conversion of the urea into crude melamine inside a first chamber delimited by a shell inside a reactor body and a secondary step of stripping said crude melamine melt inside a second reaction chamber, which is coaxial with and situated outside said first chamber, inside the same reactor body.

公开(公告)号：US20170355584A1

公开(公告)日：2017-12-14

申请号：US15177458

申请日：2016-06-09

Applicant: Space Pharma SA

Inventor： Ira NAOT ,  Yair FEUCHTWANGER ,  Molly K. MULLIGAN ,  Alexander PEKIN

IPC: B67C3/18 ,  B67C3/28

CPC classification number: B67C3/18 ,  B01J4/008 ,  B01J4/02 ,  B64G1/22 ,  B67C3/28

Abstract: A system includes rigid reservoirs, each divided by a flexible diaphragm into a hydraulic chamber and a delivery chamber. The hydraulic chamber is connected to a hydraulic liquid conduit via a valve and the delivery chamber is connected to a delivery conduit. A hydraulic actuator is operable to apply pressure to the hydraulic liquid so as to force the hydraulic liquid into a hydraulic chamber whose valve is open, pushing the diaphragm distally to force the delivery liquid from the delivery chamber into the connected delivery conduit. The actuator is also operable to apply suction to the hydraulic liquid in the hydraulic liquid conduit so as to draw hydraulic liquid from the hydraulic chamber, proximally pulling the flexible diaphragm to draw the delivery liquid from the delivery conduit into the delivery chamber.

公开(公告)号：US09802749B2

公开(公告)日：2017-10-31

申请号：US14688778

申请日：2015-04-16

Applicant: ENTEGRIS, INC

Inventor： Minna Hovinen ,  John R. Kingery ,  Glenn M. Tom ,  Kevin T. O'Dougherty ,  Kirk Mikkelsen ,  Donald D. Ware ,  Peter C. Van Buskirk

IPC: B65D83/00 ,  B01J4/02 ,  G01F23/18

CPC classification number: B65D83/0061 ,  B01J4/02 ,  B01J2219/00065 ,  B01J2219/00067 ,  B01J2219/00069 ,  B01J2219/00164 ,  G01F23/18

Abstract: Fluid supply systems for storage and dispensing of chemical reagents and compositions, e.g., high purity liquid reagents and chemical mechanical polishing compositions used to manufacture microelectronic device products, having capability for detection of an empty or near-empty condition when the contained liquid is at or approaching depletion during dispensing operation. Fluid delivery systems employing empty detect arrangements are described, including pressure transducer monitoring of dispensed material intermediate the supply package and a servo-hydraulic dispense pump, or monitoring of dispenser chamber replenishment times in a dispenser being replenished on a cyclic schedule to flow material from the dispenser to a downstream tool utilizing the dispensed material.

公开(公告)号：US09688952B2

公开(公告)日：2017-06-27

申请号：US14325892

申请日：2014-07-08

Applicant: Buerkert Werke GmbH

Inventor： Peggy Schaefer

IPC: C12M1/34 ,  C12M1/26 ,  B01J4/02 ,  B01J19/00 ,  B01L3/00 ,  C12M1/32 ,  C12M1/00

CPC classification number: C12M33/12 ,  B01J4/02 ,  B01J19/0093 ,  B01J2219/00894 ,  B01L3/502746 ,  C12M23/12 ,  C12M23/40 ,  C12M29/00

Abstract: A micro fluid dosing unit includes a test container containing biomaterial needing oxygen. The test container has at least one first container which contains water and at least one second container which contains a pharmacological substance, wherein the first and the second containers have a container outlet leading to the test container and are mounted on a common valve carrier plate containing control channels, which includes control channel ports for control valves to be coupled thereto. In the valve carrier plate a separate valve control chamber is formed for each container, which is sealed by a membrane, wherein associated container outlets are opened and closed by the membrane movement.