公开(公告)号：US20090143544A1

公开(公告)日：2009-06-04

申请号：US12328868

申请日：2008-12-05

Applicant: Zenon Lysenko ,  Bob R. Maughon ,  Jozef Bicerano ,  Kenneth A. Burdett ,  Christopher P. Christenson ,  Clark H. Cummins ,  Marvin L. Dettloff ,  Alan K. Schrock ,  P. J. Thomas ,  Richard D. Varjian ,  Jerry E. White ,  John Michael Maher

Inventor： Zenon Lysenko ,  Bob R. Maughon ,  Jozef Bicerano ,  Kenneth A. Burdett ,  Christopher P. Christenson ,  Clark H. Cummins ,  Marvin L. Dettloff ,  Alan K. Schrock ,  P. J. Thomas ,  Richard D. Varjian ,  Jerry E. White ,  John Michael Maher

IPC: C08L63/08 ,  C07C51/43 ,  C07C59/42 ,  C07C31/18 ,  C07C215/00 ,  C08L79/02 ,  C08L67/04 ,  C07C229/00 ,  C07C69/732 ,  C07C1/00

CPC classification number: C07D303/42 ,  C07C67/31 ,  C07C67/333 ,  C07C67/347 ,  C07C67/56 ,  C07C69/533 ,  C07C227/08 ,  C07C227/18 ,  C07C229/08 ,  Y02P20/125 ,  C07C69/716 ,  C07C69/675

Abstract: Integrated processes of preparing industrial chemicals starting from seed oil feedstock compositions containing one or more unsaturated fatty acids or unsaturated fatty acid esters, which are essentially free of metathesis catalyst poisons, particularly hydroperoxides; metathesis of the feedstock composition with a lower olefin, such as ethylene, to form a reduced chain olefin, preferably, a reduced chain α-olefin, and a reduced chain unsaturated acid or ester, preferably, a reduced chain α,ω-unsaturated acid or ester. The reduced chain unsaturated acid or ester may be (trans)esterified to form a polyester polyolefin, which may be epoxidized to form a polyester polyepoxide. The reduced chain unsaturated acid or ester may be hydroformylated with reduction to produce an α,ω-hydroxy acid or α,ω-hydroxy ester, which may be (trans)esterified with a polyol to form an α,ωpolyester polyol. Alternatively, the reduced chain unsaturated acid or ester may be hydroformylated with reductive amination to produce an α,ω-amino acid or α,ω-amino ester, which may be (trans)esterified to form an α,ω-polyester polyamine.

Abstract translation: 从含有一种或多种不饱和脂肪酸或不饱和脂肪酸酯的种子油原料组合物制备工业化学品的综合方法，其基本上不含复分解催化剂毒物，特别是氢过氧化物; 原料组合物与低级烯烃如乙烯的复分解以形成还原链烯烃，优选还原链的α-烯烃和还原链不饱和酸或酯，优选还原链的α，ω-不饱和酸 或酯。 还原链不饱和酸或酯可以（反式）酯化以形成聚酯聚烯烃，其可以被环氧化以形成聚酯多环氧化物。 还原链不饱和酸或酯可以通过还原加氢甲酰化以产生α，ω-羟基酸或α，ω-羟基酯，其可以与多元醇反应形成α，ω-聚酯多元醇。 或者，还原链不饱和酸或酯可以通过还原胺化加氢甲酰化以产生α，ω-氨基酸或α，ω-氨基酯，其可以（反式）酯化形成α，ω-聚酯多胺。

公开(公告)号：US20090118527A1

公开(公告)日：2009-05-07

申请号：US12294002

申请日：2007-03-15

Applicant: Eiichi Nakamura ,  Yutaka Matsuo ,  Takahiro Nakae

Inventor： Eiichi Nakamura ,  Yutaka Matsuo ,  Takahiro Nakae

IPC: C07F15/00 ,  B82B1/00 ,  B82B3/00

CPC classification number: C07C67/347 ,  C07C2604/00 ,  C07F17/00 ,  C07F17/02 ,  Y10S977/734 ,  Y10S977/74 ,  C07C69/65 ,  C07C69/76 ,  C07C69/608

Abstract: The present invention provides a method for producing a fullerene derivative comprising reacting: a serene; an organometallic reagent (A) comprising B, Al, Zn, Sn, Pb, Te, Ti, Mn, Zr or Sm; and a copper compound (B).

Abstract translation: 本发明提供一种富勒烯衍生物的制造方法，其包括： 包含B，Al，Zn，Sn，Pb，Te，Ti，Mn，Zr或Sm的有机金属试剂（A） 和铜化合物（B）。

公开(公告)号：US20090111993A1

公开(公告)日：2009-04-30

申请号：US12093664

申请日：2006-11-13

Applicant: John Oldfield ,  Ian Patel ,  Andrew Williams

Inventor： John Oldfield ,  Ian Patel ,  Andrew Williams

IPC: C07D211/34

CPC classification number: C07D211/96 ,  C07C67/347 ,  C07D211/34 ,  C07C69/65 ,  C07C69/734

Abstract: A process for preparing a compound of formula (I) comprising reacting a compound of formula (II) with a fluorinated boron species of formula (III) in the presence of: an alcohol; a rhodium (I) pre-catalyst species; a suitable ligand that binds to the rhodium (I) pre-catalyst species to form a catalyst complex; a base; and, a suitable solvent; the process being carried out at a temperature in the range 40 to 110° C. The compounds of formula (I) are useful in the preparation of pharmaceutically active compounds.

Abstract translation: 一种制备式（I）化合物的方法，包括使式（II）化合物与式（III）的氟化硼物质在醇存在下反应： 铑（I）催化前物质; 与铑（I）预催化剂物质结合以形成催化剂络合物的合适的配体; 一个基地 和合适的溶剂; 该方法在40至110℃的温度下进行。式（I）化合物可用于制备药物活性化合物。

公开(公告)号：US07402693B2

公开(公告)日：2008-07-22

申请号：US11888703

申请日：2007-08-02

Applicant: Ming-Chih Lai ,  Chia-Wen Chang ,  Chi-Wi Ong

Inventor： Ming-Chih Lai ,  Chia-Wen Chang ,  Chi-Wi Ong

IPC: C07C69/74

CPC classification number: C07C69/74 ,  C07C67/347 ,  C07C2601/04

Abstract: The invention provides a cyclobutanetetracarboxylate compound of general formula (I) and a preparation method thereof: in which R and R1 are as defined in the specification.

公开(公告)号：US20070260033A1

公开(公告)日：2007-11-08

申请号：US11693314

申请日：2007-03-29

Applicant: Jan Kamps ,  Jan-Pleun Lens ,  James Mahood ,  Arakali Radhakrishna ,  T. Raj ,  Ravindra Singh

Inventor： Jan Kamps ,  Jan-Pleun Lens ,  James Mahood ,  Arakali Radhakrishna ,  T. Raj ,  Ravindra Singh

IPC: C08G64/04

CPC classification number: C07C69/757 ,  C07C45/69 ,  C07C45/74 ,  C07C67/343 ,  C07C67/347 ,  C07C2601/14 ,  C08G64/14 ,  C07C49/223

Abstract: Disclosed herein is a process for preparing a polymer comprising structural units derived from polycyclic dihydroxy compound having Formula (I), wherein R1 is selected from the group consisting of a cyano functionality, a nitro functionality, an aliphatic functionality having 1 to 10 carbons, an aliphatic ester functionality having 2 to 10 carbons, a cycloaliphatic ester functionality having 4 to 10 carbons and an aromatic ester functionality having 4 to 10 carbons; R2 is selected from the group consisting of a cyano functionality, a nitro functionality, an aliphatic ester functionality having 2 to 10 carbons, a cycloaliphatic ester functionality having 4 to 10 carbons and an aromatic ester functionality having 4 to 10 carbons; and each R3 and R4, at each occurrence, can be the same or different and are independently at each occurrence an aliphatic functionality having 1 to 10 carbons or a cycloaliphatic functionality having 3 to 10 carbons, “n” is an integer having a value 0 to 4 and “m” is an integer having a value 0 to 4. The process comprises subjecting a polycyclic dihydroxy compound of Formula (I) to polymerization.

Abstract translation: 本文公开了一种制备包含衍生自具有式（I）的多环二羟基化合物的结构单元的聚合物的方法，其中R 1选自氰基官能团，硝基官能团，脂族基团 具有1至10个碳的官能团，具有2至10个碳的脂族酯官能团，具有4至10个碳的脂环族酯官能团和具有4至10个碳的芳族酯官能团; R 2选自氰基官能团，硝基官能团，具有2至10个碳的脂族酯官能团，具有4至10个碳的脂环族酯官能团和具有4个碳原子的芳族酯官能团 至10个碳; 并且每次出现时，每个R 3和R 4可以相同或不同，并且在每次出现时独立地为具有1至10个碳的脂族官能团或脂环族官能团 具有3至10个碳，“n”是0至4的整数，“m”是0至4的整数。该方法包括使式（I）的多环二羟基化合物进行聚合。

公开(公告)号：US07288674B2

公开(公告)日：2007-10-30

申请号：US10544494

申请日：2004-02-04

Applicant: Makoto Itagaki ,  Katsuhisa Masumoto

Inventor： Makoto Itagaki ,  Katsuhisa Masumoto

IPC: C07C61/04 ,  C07D263/10

CPC classification number: C07D263/12 ,  C07B2200/07 ,  C07C67/347 ,  C07C215/28 ,  C07C233/18 ,  C07C2601/02 ,  C07C69/747

Abstract: Optically active bisoxazoline compounds represented by the general formula (1), a process for producing the compounds, and a process for producing cyclopropanecarboxylic esters by using the same: wherein R1 and R2 are the same and each represents C1-6 alkyl, substituted or unsubstituted aralkyl, or substituted or unsubstituted phenyl or R1 and R2 are bonded each other together with the carbon atom of oxazoline ring to which they are bonded to form a ring; R3 is substituted or unsubstituted naphthyl; R4 and R5 are the same and each represent hydrogen or C1-6 alkyl, or R4 and R5 are bonded each other together with the carbon atom to which they are bonded to form a cycloalkyl ring having 3 to 6 carbon atoms; and * represents an asymmetric center.

Abstract translation: 由通式（1）表示的光学活性的双恶唑啉化合物，该化合物的制备方法以及使用该化合物制备环丙烷羧酸酯的方法：其中R 1和R 2， SUP>相同，各自表示C 1-6烷基，取代或未取代的芳烷基或取代或未取代的苯基或R 1和R 2 O 2 >与它们所键合的恶唑啉环的碳原子一起形成环; R 3是取代或未取代的萘基; R 4和R 5是相同的，并且各自表示氢或C 1-6烷基，或R 4， R 5和它们所连接的碳原子一起形成具有3〜6个碳原子的环烷基环; *表示非对称中心。

公开(公告)号：US07087797B2

公开(公告)日：2006-08-08

申请号：US10474679

申请日：2002-04-11

Applicant: Otto Erik Sielcken ,  Hubertus Adrianus Smits ,  Imre Toth

Inventor： Otto Erik Sielcken ,  Hubertus Adrianus Smits ,  Imre Toth

IPC: C07C45/50

CPC classification number: C07C45/50 ,  C07C67/347 ,  Y02P20/584 ,  C07C69/716 ,  C07C47/02

Abstract: A continuous hydroformylation process for forming an aldehyde comprising 1) reacting an olefinically unsaturated compound containing from 2 to 30 carbon atoms with carbon monoxide and hydrogen in the presence of a rhodium-bisphosphite ligand complex catalyst and 2) distilling a mixture comprising at least a part of the catalyst of 1), wherein the distilling is performed in the substantial absence of molecular hydrogen.

Abstract translation: 用于形成醛的连续加氢甲酰化方法包括：1）在二 - 二亚磷酸酯配体配合物催化剂的存在下使包含2-30个碳原子的烯属不饱和化合物与一氧化碳和氢气反应，和2）蒸馏包含至少一部分 的催化剂1），其中蒸馏在基本上不存在分子氢的情况下进行。

公开(公告)号：US20060100453A1

公开(公告)日：2006-05-11

申请号：US10504247

申请日：2003-03-04

Applicant: Wei-Jun Peng ,  David Bryant

Inventor： Wei-Jun Peng ,  David Bryant

IPC: C07F9/02 ,  C07C45/49

CPC classification number: C07F15/008 ,  C07C45/49 ,  C07C45/50 ,  C07C67/293 ,  C07C67/347 ,  C07F9/65742 ,  C07F9/65744 ,  C07F9/65746 ,  C07C47/19 ,  C07C47/228 ,  C07C69/003 ,  C07C69/716 ,  C07C69/14

Abstract: A novel organophosphorus composition and synthesis thereof, the composition being characterized by one phosphite moiety, one phosoxophite moiety, and a plurality of sterically bulky substituents. The novel composition finds utility as a ligand in Group VIII transition metal phosoxophite complex catalysts and complex catalyst precursors that are used in carbonylation processes, preferably, hydroformylation processes. Additionally, there is disclosed a novel method of preparing a phosphoromonochloridite composition that finds utility as a precursor to the novel phosoxophite composition.

Abstract translation: 一种新颖的有机磷组合物及其合成，该组合物的特征在于一个亚磷酸酯部分，一个亚磷酸酯部分和多个空间庞大的取代基。 该新型组合物可用作第VIII族过渡金属磷酸盐络合物催化剂和复合催化剂前体中的配体，其用于羰基化方法，优选加氢甲酰化方法。 此外，公开了一种制备可用作新型磷酸盐组合物的前体的一氯代氯酸盐组合物的新方法。

公开(公告)号：US07002044B2

公开(公告)日：2006-02-21

申请号：US10641705

申请日：2003-08-15

Applicant: Can Erkey ,  Xing Dong

Inventor： Can Erkey ,  Xing Dong

IPC: C07C45/50

CPC classification number: C07C45/50 ,  C07C67/347 ,  C07C69/716 ,  C07C47/02

Abstract: A microemulsion containing water, a densified fluid, a surfactant, and an organometallic catalyst is used to catalyze chemical reactions. The organometallic catalyst preferably has substantial solubility in the water phase of the microemulsion. Separation of reaction products from the microemulsion is facilitated by removal of the densified fluid.

Abstract translation: 使用含有水，致密化流体，表面活性剂和有机金属催化剂的微乳液来催化化学反应。 有机金属催化剂优选在微乳液的水相中具有相当大的溶解度。 通过去除致密化流体来促进反应产物与微乳液的分离。

公开(公告)号：US20050065349A1

公开(公告)日：2005-03-24

申请号：US10935535

申请日：2004-09-07

Applicant: Stephen Buchwald ,  Daniel Appella ,  Yasunori Moritani ,  Ryo Shintani ,  Valdas Jurkauskas

Inventor： Stephen Buchwald ,  Daniel Appella ,  Yasunori Moritani ,  Ryo Shintani ,  Valdas Jurkauskas

IPC: C07B53/00 ,  C07B57/00 ,  C07B61/00 ,  C07C45/58 ,  C07C45/62 ,  C07C45/68 ,  C07C45/78 ,  C07C67/303 ,  C07C67/347 ,  C07C253/30 ,  C07C255/33 ,  C07F7/24 ,  C07D213/57

CPC classification number: C07C253/30 ,  C07B53/00 ,  C07B57/00 ,  C07C45/58 ,  C07C45/62 ,  C07C45/68 ,  C07C45/78 ,  C07C67/303 ,  C07C67/347 ,  C40B40/00 ,  C07C255/33

Abstract: One aspect of the present invention relates to methods for the transition-metal-catalyzed asymmetric 1,4-addition of a nucleophile, e.g., hydride, to cyclic and acyclic enoates and enones. In certain embodiments of the methods of the present invention, the transition metal catalyst consists essentially of copper and an asymmetric bidentate bisphosphine ligand.

Abstract translation: 本发明的一个方面涉及过渡金属催化的亲核试剂例如氢化物的不对称1,4-加成到环状和无环烯醇酯和烯酮的方法。 在本发明方法的某些实施方案中，过渡金属催化剂基本上由铜和不对称双齿二膦配体组成。