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    Methods of polymer preparation using polycyclic dihydroxy compounds
    3.
    发明授权
    Methods of polymer preparation using polycyclic dihydroxy compounds 有权
    使用多环二羟基化合物制备聚合物的方法

    公开(公告)号：US07381786B2

    公开(公告)日：2008-06-03

    申请号：US11693314

    申请日：2007-03-29

    Applicant: Jan Henk Kamps ,  Jan-Pleun Lens ,  James A. Mahood ,  Arakali Srinivasarao Radhakrishna ,  T. Tilak Raj ,  Ravindra Vikram Singh

    Inventor： Jan Henk Kamps ,  Jan-Pleun Lens ,  James A. Mahood ,  Arakali Srinivasarao Radhakrishna ,  T. Tilak Raj ,  Ravindra Vikram Singh

    IPC: C08G63/02 ,  C07C69/76 ,  C07C67/00

    CPC classification number: C07C69/757 ,  C07C45/69 ,  C07C45/74 ,  C07C67/343 ,  C07C67/347 ,  C07C2601/14 ,  C08G64/14 ,  C07C49/223

    Abstract: Disclosed herein is a process for preparing a polymer comprising structural units derived from polycyclic dihydroxy compound having Formula (I), wherein R1 is selected from the group consisting of a cyano functionality, a nitro functionality, an aliphatic functionality having 1 to 10 carbons, an aliphatic ester functionality having 2 to 10 carbons, a cycloaliphatic ester functionality having 4 to 10 carbons and an aromatic ester functionality having 4 to 10 carbons; R2 is selected from the group consisting of a cyano functionality, a nitro functionality, an aliphatic ester functionality having 2 to 10 carbons, a cycloaliphatic ester functionality having 4 to 10 carbons and an aromatic ester functionality having 4 to 10 carbons; and each R3 and R4, at each occurrence, can be the same or different and are independently at each occurrence an aliphatic functionality having 1 to 10 carbons or a cycloaliphatic functionality having 3 to 10 carbons, “n” is an integer having a value 0 to 4 and “m” is an integer having a value 0 to 4. The process comprises subjecting a polycyclic dihydroxy compound of Formula (I) to polymerization.

    Abstract translation: 本文公开了一种制备包含衍生自具有式（I）的多环二羟基化合物的结构单元的聚合物的方法，其中R 1选自氰基官能团，硝基官能团，脂族基团 具有1至10个碳的官能团，具有2至10个碳的脂族酯官能团，具有4至10个碳的脂环族酯官能团和具有4至10个碳的芳族酯官能团; R 2选自氰基官能团，硝基官能团，具有2至10个碳的脂族酯官能团，具有4至10个碳的脂环族酯官能团和具有4个碳原子的芳族酯官能团 至10个碳; 并且每次出现时，每个R 3和R 4可以相同或不同，并且在每次出现时独立地为具有1至10个碳的脂族官能团或脂环族官能团 具有3至10个碳，“n”是0至4的整数，“m”是0至4的整数。该方法包括使式（I）的多环二羟基化合物进行聚合。

    4-Biphenylyl-4-hydroxyalkan-2-ones
    10.
    发明授权
    4-Biphenylyl-4-hydroxyalkan-2-ones 失效
    4-联苯基-4-羟基烷基-2-酮

    公开(公告)号：US4228105A

    公开(公告)日：1980-10-14

    申请号：US964046

    申请日：1978-11-27

    Applicant: Rudiger Jeck

    Inventor： Rudiger Jeck

    IPC: C07D295/10 ,  C07C45/00 ,  C07C45/51 ,  C07C45/66 ,  C07C49/20 ,  C07C49/223 ,  C07C49/225 ,  C07C49/235 ,  C07C49/24 ,  C07C49/252 ,  C07C67/00 ,  C07C213/00 ,  C07C225/22 ,  C07C241/00 ,  C07C251/16 ,  C07D295/112 ,  C07C49/82

    CPC classification number: C07D295/112 ,  C07C45/516 ,  C07C45/66 ,  C07C49/223 ,  C07C49/225 ,  C07C49/235 ,  C07C49/252

    Abstract: A process for the production of compounds of formula I, ##STR1## wherein R.sub.1 is alkyl of 1 to 3 carbon atoms,R.sub.2 is hydrogen, fluorine, chlorine or bromine, andR.sub.3 is bromine, iodine, isobutyl, tert. butyl, cyclohexyl, cyclohexenyl; or phenyl, optionally substituted by fluorine, chlorine, bromine or alkoxy of 1 to 4 carbon atoms; or a radical of formula II, ##STR2## in which either R.sub.4 and R.sub.5 are the same or different and each signifies alkyl of 1 to 3 carbon atoms, orR.sub.4 and R.sub.5 together signify the radical --(CH.sub.2).sub.n --, in which n is 4 or 5, the radical --CH.sub.2 --CH.sub.2 --0--CH.sub.2 --CH.sub.2 --, the radical --CH.sub.2 --CH.dbd.CH--CH.sub.2 --, or the radical --CH.sub.2 --CH.sub.2 --N(R.sub.6)--CH.sub.2 --CH.sub.2 --, in which R.sub.6 is hydrogen or alkyl of 1 to 3 carbon atoms. Hydroxyketone and hydroxy imine intermediates are also disclosed.The compounds of formula I are known to exhibit anti-inflammatory activity.

    Abstract translation: 制备式I化合物的方法，其中R 1为1至3个碳原子的烷基，R 2为氢，氟，氯或溴，R 3为溴，碘，异丁基，叔丁基。 丁基，环己基，环己烯基; 或苯基，任选被氟，氯，溴或具有1至4个碳原子的烷氧基取代; 或式II的基团，其中R 4和R 5相同或不同，并且各自表示1至3个碳原子的烷基，或者R 4和R 5一起表示基团 - （CH 2）n - ，其中 基团-CH 2 -CH 2 -O-CH 2 -CH 2 - ，基团-CH 2 -CH = CH-CH 2 - 或基团-CH 2 -CH 2 -N（R 6）-CH 2 -CH 2 - 其中R 6是氢或1至3个碳原子的烷基。 还公开了羟基酮和羟基亚胺中间体。 已知式I化合物具有抗炎活性。

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