摘要:
Compounds that regulate quorum sensing in Staphylococcal bacteria and in particular in Staphylococcus aureus are provided. Compounds are described in formulas I, II, III, IV, V and VI herein. One or more compounds herein can be employed to inhibit QS and to thus inhibit virulence in Staphylococcus bacteria and in particular in Staphylococcus aureus. Compounds herein and pharmaceutical compositions containing one or more of these compounds are useful, for example, in treating infections of Staphylococcus bacteria and in particular of Staphylococcus aureus. Methods for treating such bacterial infections are provided.
摘要:
Provided are compounds and pharmaceutically acceptable salts thereof, their pharmaceutical compositions, their methods of preparation, and methods for their use in the prevention and/or treatment of HIV; including the prevention of the progression of AIDS and general immunosuppression.
摘要:
A polyester film including a cyclic carbodiimide compound represented by the following Formula (O-1) has good film thickness uniformity without increase in viscosity. R1 and R5 represent an alkyl group, an aryl group, or an alkoxy group; R2 to R4 and R6 to R8 represent a hydrogen atom, an alkyl group, an aryl group, or an alkoxy group; X1 and X2 represent a single bond, —O—, —CO—, —S—, —SO2—, —NH—, or —CH2—; and L1 represents a divalent linking group.
摘要:
A polyester film including a cyclic carbodiimide compound represented by the following Formula (O-1) has good film thickness uniformity without increase in viscosity. R1 and R5 represent an alkyl group, an aryl group, or an alkoxy group; R2 to R4 and R6 to R8 represent a hydrogen atom, an alkyl group, an aryl group, or an alkoxy group; X1 and X2 represent a single bond, —O—, —CO—, —S—, —SO2—, —NH—, or —CH2—; and L1 represents a divalent linking group.
摘要翻译:包含由下式(O-1)表示的环状碳二亚胺化合物的聚酯膜具有良好的膜厚均匀性,而不增加粘度。 R1和R5表示烷基,芳基或烷氧基; R2至R4和R6至R8表示氢原子,烷基,芳基或烷氧基; X 1和X 2表示单键,-O - , - CO - , - S - , - SO 2 - , - NH-或-CH 2 - ; 并且L 1表示二价连接基团。
摘要:
Compounds and compositions are provided for treatment, prevention, or amelioration of a variety of medical disorders associated with viral infections, cell proliferation and bone metabolism. The compounds provided herein are alkyl esters of phosphonates.
摘要:
The present invention provides an HCV polymerase inhibiting compound having the formula (I) and a composition comprising a therapeutically effective amount of said compound. The present invention also provides a method for inhibiting hepatitis C virus (HCV) polymerase, a method for inhibiting HCV viral replication, and a method for treating or preventing HCV infection. Processes for making said compounds, and synthetic intermediates employed in said processes, are also provided.