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    Expandable guide sheath with steerable backbone and methods for making and using them
    51.
    发明授权
    Expandable guide sheath with steerable backbone and methods for making and using them 有权
    具有可转向骨架的可扩展导向护套及其制造和使用方法

    公开(公告)号：US07875049B2

    公开(公告)日：2011-01-25

    申请号：US11347361

    申请日：2006-02-03

    申请人： Christian S. Eversull ,  Stephen A. Leeflang ,  Nicholas J. Mourlas ,  Christine P. Ventura

    发明人： Christian S. Eversull ,  Stephen A. Leeflang ,  Nicholas J. Mourlas ,  Christine P. Ventura

    IPC分类号： A61M29/00

    CPC分类号： A61M25/0662 ,  A61B17/3439 ,  A61M2025/0024

    摘要： Apparatus and methods are provided for providing access to a body lumen. The apparatus includes a tubular member including a proximal end, a distal end sized for insertion into a body lumen, and a lumen extending therebetween. A pushable stiffening member extends from the distal end of the tubular member. An expandable sheath extends along at least a portion of the stiffening member, the sheath being expandable from a contracted condition to facilitate insertion into a body lumen, and an enlarged condition wherein the sheath at least partially defines a lumen communicating with the tubular member lumen. A distal portion of the sheath is steerable, e.g., using a pull wire disposed within a lumen of the sheath or within the stiffening member. In addition or alternatively, the stiffening member may be biased to a predetermined shape to facilitate introduction.

    摘要翻译： 提供了用于提供对体腔的接近的装置和方法。 该装置包括管状构件，该管状构件包括近端，尺寸适于插入体腔的远端和在其间延伸的内腔。 推动加强构件从管状构件的远端延伸。 可扩张护套沿着加强构件的至少一部分延伸，护套可从收缩状态扩展以便于插入体腔，以及扩大状态，其中护套至少部分地限定与管状构件腔连通的内腔。 护套的远端部分是可操纵的，例如使用设置在鞘的内腔内或加强构件内的拉线。 另外或替代地，加强构件可被偏压到预定形状以便于引入。

    VALVES AND HUBS FOR TUBULAR DEVICES AND METHODS FOR MAKING AND USING THEM
    52.
    发明申请
    VALVES AND HUBS FOR TUBULAR DEVICES AND METHODS FOR MAKING AND USING THEM 有权
    用于制造和使用它们的管状装置的阀和阀和方法

    公开(公告)号：US20110004223A1

    公开(公告)日：2011-01-06

    申请号：US12581826

    申请日：2009-10-19

    申请人： Stephen A. Leeflang ,  Christian S. Eversull

    发明人： Stephen A. Leeflang ,  Christian S. Eversull

    IPC分类号： A61M39/02 ,  A61M39/00 ,  F16K1/32 ,  B23P11/00 ,  B21D51/16

    CPC分类号： A61M25/0014 ,  A61M39/0606 ,  A61M39/0693 ,  A61M2039/0633 ,  A61M2039/064 ,  A61M2207/00 ,  B21D28/32 ,  F16K51/00 ,  Y10T29/49405 ,  Y10T29/49826

    摘要： A hub for a sheath, catheter, or other tubular device includes a first hub portion including a first hub lumen sized for receiving a medical device therethrough, and a second hub portion including a second hub lumen, the second hub portion coupled to the first hub portion such that the first and second hub lumens are aligned with one another and the first and second hub portions are spaced apart from one another to define a gap. A valve is secured within the gap between the first and second hub portions that includes a valve passage therethrough, e.g., for accommodating receiving a medical device through the first and second hub lumens into the tubular device, while providing a substantially fluid tight seal. For example, the valve passage may include a bore extending partially from a first end of the valve towards a second end of the valve, and a slit that extends from the end of the bore to the second end of the valve.

    摘要翻译： 用于护套，导管或其它管状装置的轮毂包括第一毂部分，其包括尺寸适于接收穿过其中的医疗装置的第一轮毂腔和包括第二轮毂腔的第二轮毂部分，第二轮毂部分联接到第一轮毂 使得第一和第二毂腔彼此对准并且第一和第二毂部彼此间隔开以限定间隙。 阀被固定在第一和第二轮毂​​部分之间的间隙内，该第一和第二轮毂​​部分包括通过其的阀通道，例如用于通过第一和第二轮毂​​腔容纳医疗装置进入管状装置，同时提供基本上流体密封的密封。 例如，阀通道可以包括从阀的第一端向阀的第二端部分延伸的孔，以及从孔的端部延伸到阀的第二端的狭缝。

    APPARATUS AND METHODS FOR MAKING COATED LINERS AND TUBULAR DEVICES INCLUDING SUCH LINERS
    54.
    发明申请
    APPARATUS AND METHODS FOR MAKING COATED LINERS AND TUBULAR DEVICES INCLUDING SUCH LINERS 有权
    用于制造涂层衬套和包括这种衬里的管状装置的装置和方法

    公开(公告)号：US20100206453A1

    公开(公告)日：2010-08-19

    申请号：US12708526

    申请日：2010-02-18

    申请人： Stephen A. Leeflang ,  Christian S. Eversull

    发明人： Stephen A. Leeflang ,  Christian S. Eversull

    IPC分类号： B32B37/14 ,  B23P25/00 ,  B05D3/00

    CPC分类号： A61M25/0009 ,  A61M25/0012 ,  A61M25/0045 ,  A61M25/005 ,  A61M2207/00 ,  B29C53/42 ,  B29C53/50 ,  B29C53/60 ,  B29C61/006 ,  B29D23/001 ,  B29K2101/12 ,  B29L2031/7542 ,  Y10T29/49885 ,  Y10T156/10 ,  Y10T156/1013 ,  Y10T156/1036 ,  Y10T156/1038 ,  Y10T156/1067

    摘要： Apparatus and methods are provided for making coated liners and/or tubular devices including such coated liners. A sleeve may be provided that includes an outer first surface and an inner second surface extending between first and second ends thereof, and a hydrophilic or other coating may be applied to the first. The coated sleeve may be cut between the first and second ends to create opposing edges extending between the first and second ends, and the cut sleeve may be reversed such that the coated first surface defines an inner surface and the opposing edges are disposed adjacent one another, thereby providing a coated liner. Optionally, a tubular structure, e.g., one or more reinforcing layers and/or or outer layers may be attached around the coated liner, thereby providing a tubular device including an inner surface with a desired coating.

    摘要翻译： 提供了用于制造包括这种涂层衬垫的涂覆衬里和/或管状装置的装置和方法。 可以提供包括外部第一表面和在其第一和第二端之间延伸的内部第二表面的套筒，并且亲水或其它涂层可以施加到第一表面。 涂覆的套筒可以在第一和第二端之间切割以形成在第一和第二端之间延伸的相对边缘，并且切割套筒可以颠倒，使得涂覆的第一表面限定内表面，并且相对的边缘彼此相邻地设置 ，从而提供涂层衬垫。 任选地，管状结构，例如一个或多个加强层和/或外层可以附着在涂覆的衬里周围，从而提供包括具有期望涂层的内表面的管状装置。

    Expandable guide sheath and apparatus and methods for making them
    56.
    发明授权
    Expandable guide sheath and apparatus and methods for making them 有权
    可扩展导套及其制造方法

    公开(公告)号：US07713281B2

    公开(公告)日：2010-05-11

    申请号：US10958034

    申请日：2004-10-04

    申请人： Stephen A. Leeflang ,  Christine P. Ventura ,  Christian S. Eversull ,  Nicholas J. Mourlas ,  Christopher Loew

    发明人： Stephen A. Leeflang ,  Christine P. Ventura ,  Christian S. Eversull ,  Nicholas J. Mourlas ,  Christopher Loew

    IPC分类号： A61M29/00

    CPC分类号： A61M25/0662 ,  A61B17/3439 ,  A61M25/003 ,  A61M2025/0024 ,  A61M2025/0035 ,  A61N1/056

    摘要： Apparatus and methods are provided for providing access to a body lumen. The apparatus includes a tubular member including a proximal end, a distal end sized for insertion into a body lumen, and a lumen extending between the proximal and distal ends. A pushable stiffening member extends from the distal end of the tubular member, the elongate member terminating in a distal tip. An expandable sheath extends along at least a portion of the stiffening member, the sheath being expandable from a contracted condition to minimize a profile of the sheath to allow insertion along with the stiffening member into a body lumen, and an enlarged condition wherein the sheath at least partially defines a lumen communicating with the tubular member lumen. In one embodiment, the sheath includes an outer lumen and an inner lumen floating within the outer lumen, and the stiffening member is carried in the inner lumen.

    摘要翻译： 提供了用于提供对体腔的接近的装置和方法。 该装置包括管状构件，其包括近端，尺寸适于插入体腔的远端以及在近端和远端之间延伸的内腔。 可推动加强构件从管状构件的远端延伸，细长构件终止于远端。 可扩张护套沿着加强构件的至少一部分延伸，护套可以从收缩状态扩展，以最小化护套的轮廓，以允许将加强构件插入体腔内，并且扩大状态，其中护套 至少部分地限定与所述管状构件内腔连通的管腔。 在一个实施例中，护套包括外腔和漂浮在外腔内的内腔，并且加强构件承载在内腔中。

    SLITTABLE OR REMOVABLE VALVES AND APPARATUS AND METHODS FOR MAKING AND USING THEM
    58.
    发明申请
    SLITTABLE OR REMOVABLE VALVES AND APPARATUS AND METHODS FOR MAKING AND USING THEM 有权
    可变的或可拆卸的阀门，以及用于制造和使用它们的装置和方法

    公开(公告)号：US20100042049A1

    公开(公告)日：2010-02-18

    申请号：US12603602

    申请日：2009-10-22

    申请人： Stephen A. Leeflang ,  Christine P. Ventura ,  Christian S. Eversull ,  Nicholas J. Mourlas

    发明人： Stephen A. Leeflang ,  Christine P. Ventura ,  Christian S. Eversull ,  Nicholas J. Mourlas

    IPC分类号： A61M25/00 ,  A61B17/34

    CPC分类号： A61M39/22 ,  A61M25/0668 ,  A61M39/06 ,  A61M39/0606

    摘要： A system and/or apparatus for delivering a medical device into a body includes an elongate tubular member and a valve fitted within a proximal end thereof. The valve preferably includes a tubular body and a flap, wherein the tubular body is engaged within the proximal end of the tubular member and has an open end approximately aligned with a proximal termination of the proximal end of the tubular member. The flap of the valve preferably extends over a hole formed in an end wall of the tubular body opposite a side of the end wall that faces a passage of the tubular body, which passage extends between the open end and the end wall. The hole communicates with the passage and with the lumen of the tubular member, and the flap is movable away from the hole when the device is introduced through the passage and the hole.

    摘要翻译： 用于将医疗装置输送到体内的系统和/或装置包括细长的管状构件和安装在其近端内的阀。 阀优选地包括管状体和瓣，其中管状体接合在管状构件的近端内，并且具有大致与管状构件的近端的近端连接的开口端。 阀的翼片优选地延伸在形成在管状体的端壁中的孔上，该孔与端壁的面向管状体的通道的侧面相对，该通道在开口端和端壁之间延伸。 孔与通道和管状构件的内腔连通，并且当装置通过通道和孔引入时，翼片可移动离开孔。

    Mechanical pump for removal of fragmented matter and methods of manufacture and use
    59.
    发明授权
    Mechanical pump for removal of fragmented matter and methods of manufacture and use 有权
    用于去除碎片物质的机械泵及其制造和使用方法

    公开(公告)号：US06702830B1

    公开(公告)日：2004-03-09

    申请号：US09590915

    申请日：2000-06-09

    申请人： Denise M. Demarais ,  Stephen A. Leeflang ,  Michael A. Evans ,  Gwendolyn A. Watanabe ,  John C. Tanner, III ,  Christian S. Eversull

    发明人： Denise M. Demarais ,  Stephen A. Leeflang ,  Michael A. Evans ,  Gwendolyn A. Watanabe ,  John C. Tanner, III ,  Christian S. Eversull

    IPC分类号： A61B1722

    CPC分类号： A61B17/320725 ,  A61B2017/00685 ,  A61M25/0023 ,  A61M29/02

    摘要： Material transport catheters and methods for their use rely on rotation of an impeller within a catheter body. The impeller preferably comprises an inner tube or shaft having a helical rotor formed over an outer surface thereof. Optionally, in the case of a tubular shaft, a second helical rotor may be provided within the shaft lumen in order to induce flow in opposite or in the same direction as induced by the outer helical rotor. Catheters may further comprise structures near their distal ends for disrupting clot, and are preferably introduceable over guidewires where the helical rotors are rotated directly over the guidewire. The catheters may include two or more impellers or impellers having two or more rotors in order to provide for circulation of materials at a target site within a patient body lumen.

    摘要翻译： 材料输送导管及其使用方法依赖于导管主体内的叶轮的旋转。 叶轮优选地包括在其外表面上形成有螺旋转子的内管或轴。 可选地，在管状轴的情况下，第二螺旋转子可以设置在轴腔内，以便引起与由外螺旋转子引起的相反或相同方向的流动。 导管还可以包括在其远端附近的结构以破坏凝块，并且优选地可以通过导丝线引导，其中螺旋转子直接在导丝上旋转。 导管可以包括具有两个或更多个转子的两个或多个叶轮或叶轮，以便提供材料在患者体腔内的目标部位的循环。