公开(公告)号：US20240120817A1

公开(公告)日：2024-04-11

申请号：US18267103

申请日：2020-12-23

Applicant: Mitsubishi Electric Corporation ,  OSAKA UNIVERSITY

Inventor： Haruyuki KOMETANI ,  Ryoji MIYATAKE ,  Takuro YAMADA ,  Kenji TANAKA ,  Katsuhiro HIRATA ,  Noboru NIGUCHI ,  Kazuaki TAKAHARA ,  Hironori SUZUKI ,  Takuya ITO

IPC: H02K16/02 ,  H02K1/16 ,  H02K1/2706 ,  H02K3/28

CPC classification number: H02K16/02 ,  H02K1/16 ,  H02K1/2706 ,  H02K3/28 ,  H02K2213/03

Abstract: A permanent magnet-type rotary electric machine includes a stator, a first rotor, and a second rotor. The stator includes a stator core, a plurality of stator teeth, a plurality of stator slots, a plurality of stator magnets, and a stator coil. The first rotor is disposed inside the stator core relative to the plurality of stator magnets. The second rotor is disposed inside the stator core relative to a plurality of first pole pieces. The second rotor includes a plurality of second pole pieces. A proportion of the number of the plurality of stator slots to the number of poles of the plurality of second pole pieces of the second rotor is greater than 1.25 and less than 1.5, or greater than 1.5 and less than 3.0.

公开(公告)号：US11932696B2

公开(公告)日：2024-03-19

申请号：US17134775

申请日：2020-12-28

Applicant: Shionogi & Co., Ltd. ,  Osaka University

Inventor： Tetsuya Yoshida ,  Yujiro Kidani ,  Mitsunobu Matsumoto ,  Takayuki Kanazawa ,  Satomi Shinonome ,  Kanji Hojo ,  Naganari Ohkura ,  Shimon Sakaguchi ,  Atsushi Tanaka ,  Hisashi Wada ,  Atsunari Kawashima ,  Norio Nonomura

IPC: C07K16/28 ,  A61K9/00 ,  A61K35/17 ,  A61K39/00 ,  A61K47/60 ,  A61K47/64 ,  A61K47/68 ,  A61P35/00 ,  G01N33/50

CPC classification number: C07K16/2866 ,  A61K9/0019 ,  A61K35/17 ,  A61K47/60 ,  A61K47/6435 ,  A61K47/6883 ,  A61P35/00 ,  C07K16/2818 ,  C07K16/2827 ,  G01N33/5011 ,  A61K2039/505 ,  A61K2039/507 ,  A61K2039/572 ,  C07K2317/732 ,  C07K2317/76

Abstract: The present invention provides a pharmaceutical composition for cancer treatment comprising an antibody against CCR8.

公开(公告)号：US20240082637A1

公开(公告)日：2024-03-14

申请号：US18273767

申请日：2021-12-13

Applicant: OSAKA UNIVERSITY

Inventor： Ken NAKATA ,  Takashi KANAMOTO

IPC: A63B24/00

CPC classification number: A63B24/0006 ,  A63B24/0062 ,  A63B24/0075 ,  A63B2024/0065

Abstract: An exercise support apparatus includes an information processing unit that supports a setting of a next exercise menu for improvement to a targeted body, based on prior body motion information on a subject detected by a motion sensor. The information processing unit includes an image display processing unit that outputs distribution information on an amount of activity and a number of steps of at least one category obtained by classifying activity intensity that has been obtained from a target people group in advance, for each of the selected category, stored in a storage unit, and selected in advance, to a display unit, an activity amount processing unit that calculates the amount of activity and the number of steps for a same category as a selected category, based on body motion information on the subject, and that stores a calculation result in a measurement data storage unit, and an image display processing unit that outputs the amount of activity and the number of steps that have been calculated by the activity amount processing unit, to the display unit.

公开(公告)号：US20240081767A1

公开(公告)日：2024-03-14

申请号：US18271977

申请日：2022-02-18

Applicant: OSAKA UNIVERSITY

Inventor： Yoshie SUGIYAMA

IPC: A61B6/00

CPC classification number: A61B6/5217 ,  A61B6/504 ,  A61B5/055

Abstract: A wall thickness estimation method includes: obtaining behavioral information based on a video in which an organ wall or a blood vessel wall is captured using four-dimensional angiography, the behavioral information being numerical information about changes over time in a position of each of a plurality of predetermined points in the organ wall or the blood vessel wall; generating, based on the behavioral information obtained in the obtaining, estimation information that visualizes a strain of each of the plurality of predetermined points for estimating a thickness of the organ wall or a thickness of the blood vessel wall; and outputting the estimation information generated in the generating.

公开(公告)号：US20240060878A1

公开(公告)日：2024-02-22

申请号：US18287336

申请日：2022-03-24

Applicant: OSAKA UNIVERSITY

Inventor： Susumu UCHIYAMA ,  Takahiro MARUNO ,  Tetsuo TORISU

IPC: G01N21/33 ,  G16B40/10

CPC classification number: G01N21/33 ,  G16B40/10

Abstract: An objection is to provide a method for characterizing a molecule delivery particle, the method comprising determining a molar concentration thereof.
The method for characterizing a molecule delivery particle, the method comprising subjecting a molecule delivery particle comprising a first particle and a second particle to particle separation with optical measurement to determine an increment in refractive index of each of the first particle and the second particle; and determining a molar concentration of each of the first particle and the second particle based on the increment in refractive index, a molecular weight, and a specific refractive index increment of each of the first particle and the second particle.

公开(公告)号：US20240050460A1

公开(公告)日：2024-02-15

申请号：US18152249

申请日：2023-01-10

Applicant: StemRIM Inc. ,  Osaka University

Inventor： Katsuto TAMAI ,  Takehiko YAMAZAKI ,  Yasufumi KANEDA

IPC: A61K31/711 ,  G01N33/68 ,  C07K14/52 ,  G01N33/50

CPC classification number: A61K31/711 ,  G01N33/6863 ,  C07K14/52 ,  G01N33/5073 ,  A61K38/00

Abstract: The present inventors revealed the following for the first time in the world:



1) a large amount of bone marrow-derived cells are mobilized to grafted skin;
2) the mobilized bone marrow-derived cells are differentiated into any of dermal fibroblasts, adipocytes, muscle cells, vascular endothelial cells, and epidermal keratinocytes in the grafted skin, and the mobilized bone marrow-derived cells include bone marrow-derived mesenchymal stem cells;
3) the factors which mobilize bone marrow-derived mesenchymal stem cells from peripheral blood to the grafted skin are HMGB1, HMGB2, and HMGB3 released from the necrosed tissue of recipient skin;
4) purified HMGB1, HMGB2, and HMGB3 promote the migration of mesenchymal stem cells isolated and cultured from bone marrow;
5) activators containing HMGB1 which allows the migration of bone marrow mesenchymal stem cells can be conveniently purified from several organ extracts including skin, brain, and heart;
6) activators which allow the migration of bone marrow mesenchymal stem cells can be conveniently extracted from cultured cells; and
7) a heparin-column purified fraction of skin extract mobilizes a large amount of bone marrow-derived cells in case of brain injury.

公开(公告)号：US11865637B2

公开(公告)日：2024-01-09

申请号：US16089878

申请日：2017-03-30

Applicant: MURATANI MACHINE INC. ,  ISHIKAWA PREFECTURE ,  OSAKA UNIVERSITY

Inventor： Sotohiro Muratani ,  Masahiro Tsukamoto ,  Yoshinori Funada ,  Yorihiro Yamashita

IPC: B23K26/064 ,  B23K26/21 ,  B23K26/14 ,  B23K26/34 ,  B23K26/146 ,  B23K26/342

CPC classification number: B23K26/064 ,  B23K26/14 ,  B23K26/146 ,  B23K26/21 ,  B23K26/34 ,  B23K26/342

Abstract: A laser machining device includes a plurality of optical fibers and a collimator lens arranged in parallel along a supply nozzle for supplying a molten material, and a laser beam projected from the optical fiber is applied onto an axis between a tip of the supply nozzle and a build-up welding spot.

公开(公告)号：US11860484B2

公开(公告)日：2024-01-02

申请号：US17620349

申请日：2019-06-18

Applicant: OSAKA UNIVERSITY

Inventor： Sunri Lee ,  Giichi Shibuya ,  Hiroyuki Yoshida ,  Masanori Ozaki

IPC: G02F1/1339 ,  G02F1/1337 ,  G02F1/1343 ,  G02F1/29

CPC classification number: G02F1/13394 ,  G02F1/1337 ,  G02F1/13398 ,  G02F1/134381 ,  G02F1/294

Abstract: A liquid crystal element (100) includes a plurality of unit electrodes (10), a liquid crystal layer (LQ), and a plurality of wall members (WL). Each of the unit electrodes (10) includes a first electrode (1) and a second electrode (2). A voltage is applied to the liquid crystal layer (LQ) from each of the unit electrodes (10). The wall members (WL) are arranged in the liquid crystal layer (LQ). The liquid crystal layer (LQ) has a waveform retardation (RT). Two or more of a plurality of peaks (P1) in the retardation (RT) correspond to positions of respective wall members (WL).

公开(公告)号：US11839697B2

公开(公告)日：2023-12-12

申请号：US16621528

申请日：2018-06-19

Applicant: Osaka University

Inventor： Kohji Nishida ,  Motokazu Tsujikawa ,  Susumu Hara ,  Satoshi Kawasaki ,  Masahito Yoshihara ,  Masayoshi Itoh ,  Hideya Kawaji

IPC: A61L27/38 ,  C12Q1/06 ,  C12Q1/6869 ,  A61K35/545 ,  C12N5/079 ,  A61K35/30 ,  C12Q1/6883 ,  A61K35/28

CPC classification number: A61L27/3808 ,  A61K35/30 ,  A61K35/545 ,  A61L27/38 ,  C12N5/0621 ,  C12Q1/06 ,  C12Q1/6869 ,  A61K35/28 ,  C12Q1/6883 ,  C12Q2600/158

Abstract: Provided is a means for identifying cells suitable for transplantation into a cornea, or a means for producing a cell population suitable for transplantation into a cornea using the same. A method for producing a cell population suitable for transplantation into a cornea, the method comprising the steps of (1) preparing a cell population cultured under conditions suitable for inducing differentiation into corneal endothelial cells, and (2) measuring the expression of at least one gene selected from the group consisting of POU6F2, LMX1B, and TFAP2B in the cell population.

公开(公告)号：US11835548B2

公开(公告)日：2023-12-05

申请号：US17911572

申请日：2021-03-25

Applicant: OSAKA UNIVERSITY

Inventor： Yasuhiro Sugawara

IPC: G01Q60/30 ,  G01Q60/32 ,  G01Q30/20

CPC classification number: G01Q60/30 ,  G01Q30/20 ,  G01Q60/32

Abstract: In order to increase the order of a frequency of an AC signal to be applied between a vibration section and a sample to an order at substantially the same level as the order of a vibration frequency of the vibration section in measuring a vibration component of the vibration control section, a vibration component measuring device (2) includes: a vibration section (4); a first AC signal generator (20) configured to generate a first AC signal; a second AC signal generator (44) configured to generate a second AC signal having a frequency which is (a) more than one time and less than two times or (b) more than two times and less than three times as high as a frequency of the first AC signal; a signal applying section (14, 56) configured to apply the second AC signal between the vibration section and a sample (X); a vibration control section (10) configured to cause the vibration section to vibrate; and a measuring section (16, 18, 20, 22, 42, 44, 50) configured to measure a varying component of vibration of the vibration section, the varying component being varied by an interaction between the vibration section and the sample.