公开(公告)号：US06356212B1

公开(公告)日：2002-03-12

申请号：US09506612

申请日：2000-02-18

申请人： Paul Wallace Lyons ,  Alfonse Anthony Acampora ,  John Prickett Beltz ,  Victor Vincent D'Alessandro ,  Clifford Arthur Pecota

发明人： Paul Wallace Lyons ,  Alfonse Anthony Acampora ,  John Prickett Beltz ,  Victor Vincent D'Alessandro ,  Clifford Arthur Pecota

IPC分类号： H03M700

CPC分类号： H04N21/4302 ,  H04N7/52 ,  H04N21/242 ,  H04N21/4305

摘要： A device and method for utilizing a single clock signal to generate a digital data stream signal for transmission in a compressed domain transmission system. The device includes a plurality of packetized elementary stream encoders electronically coupled to a transport stream encoder electronically coupled to an output interface adapted to generate the digital data stream signal. The method includes: operating each of the packetized elementary stream encoders responsively to the single clock sequence to generate a plurality of packetized elementary stream signals; operating the transport stream encoder responsively to the single clock signal to form a transport stream signal from the plurality of packetized elementary stream signals, wherein the transport stream signal includes a plurality of data packets each formed using the transport stream encoder and select ones of the plurality of data packets formed by the transport stream encoder include synchronization data; and, operating the output interface responsively to the single clock reference to output the digital data stream signal in compliance with an predefined manner.

摘要翻译： 一种用于利用单个时钟信号产生用于在压缩域传输系统中传输的数字数据流信号的装置和方法。 该设备包括电子耦合到传输流编码器的多个分组化的基本流编码器，电子耦合到适于生成数字数据流信号的输出接口。 该方法包括：响应于单个时钟序列操作每个分组化的基本流编码器以产生多个分组化的基本流信号; 响应于单个时钟信号操作传输流编码器以形成来自多个分组化的基本流信号的传输流信号，其中传输流信号包括多个数据分组，每个数据分组使用传输流编码器形成，并且选择多个 由传输流编码器形成的数据分组包括同步数据; 并且响应于单个时钟参考来操作输出接口以按照预定义的方式输出数字数据流信号。

公开(公告)号：US6081650A

公开(公告)日：2000-06-27

申请号：US750442

申请日：1996-12-06

申请人： Paul Wallace Lyons ,  Alfonse Anthony Acampora

发明人： Paul Wallace Lyons ,  Alfonse Anthony Acampora

IPC分类号： H04N7/32 ,  H04N7/54 ,  H04N21/236 ,  H04N21/434 ,  H04N5/76

CPC分类号： H04N21/434 ,  H04N19/152 ,  H04N21/236 ,  H04N7/54 ,  H04N19/50

摘要： A transmitted high definition television signal is represented by a packetized datastream configured as a sequence of data fields (FIG. 1) with a non-uniform data rate due to unequal inter-data overhead information intervals. Each data field is prefaced by a Field Sync overhead segment followed by 312 packetized data segments each with associated overhead information (FEC). At a transmitter (FIG. 33), a transport processor (14) forms data packets with associated headers and exhibits uninterrupted operation at a constant uniform data rate, while supplying a packetized datastream to a network (17) which constructs sequential data fields by inserting the non-data overhead information into the datastream. The transport processor is advantageously operated at a constant uniform data rate without having to modify the original data field structure to accommodate the needs of the data field construction network. This result is facilitated by transferring data from the transport processor to an associated interface/buffer network (46) in response to a 3/8 symbol clock, in combination with a predetermined buffer fullness level. Specifically, a video recorder/playback device (15) receives a constant uniform data rate packetized datastream from the transport processor, and outputs a constant uniform data rate datastream to the interface/buffer network. A counterpart transport processor/decoder (86) at a receiver (FIG. 34) coacts with a data field processor (75) and similarly exhibits uninterrupted operation at a constant uniform data rate. A video recorder/playback device (85) receives a constant uniform data rate datastream from an interface/buffer (84) after removal of overhead information, and outputs a constant uniform data rate datastream to the transport decoder.

公开(公告)号：US6025481A

公开(公告)日：2000-02-15

申请号：US80554

申请日：1998-05-18

申请人： T. Paul Wallace ,  William J. Harris ,  Frank J. Carr ,  Lloyd J. Old ,  Sydney Welt ,  Kunio Kitamura

发明人： T. Paul Wallace ,  William J. Harris ,  Frank J. Carr ,  Lloyd J. Old ,  Sydney Welt ,  Kunio Kitamura

IPC分类号： C07K16/30 ,  C07H21/02 ,  C12N1/20 ,  C12N5/00 ,  C12N15/00

CPC分类号： C07K16/30 ,  A61K2039/505 ,  C07K2317/24 ,  C07K2319/00

摘要： The invention provides for the production of several humanized murine antibodies specific for the Lewis b antigen, which is recognized by the murine antibody 58-1066. The antigen is expressed on cell lines from colon, lung, bladder, breast, renal, pancreatic and ovarian cancers. The expression of the antigen is greatly increased in cancer tissues as compared to its expression in the corresponding normal tissue. The invention also provides for numerous polynucleotide encoding humanized Lewis b antigen specific antibodies, expression vectors for producing humanized Lewis b antigen specific antibodies, and host cells for the recombinant production of the humanized antibodies. The invention also provides methods for detecting cancerous cells (in vitro and in vivo) using humanized Lewis b antigen specific antibodies. Additionally, the invention provides methods of treating cancer using Lewis b antigen specific antibodies.

摘要翻译： 本发明提供了生产针对Lewis b抗原特异性的几种人源化鼠抗体，其被鼠抗体58-1066识别。 抗原在结肠癌，肺癌，膀胱癌，乳腺癌，肾癌，胰腺癌和卵巢癌的细胞系中表达。 与其相应的正常组织中的表达相比，癌组织中抗原的表达大大增加。 本发明还提供编码人源化Lewis B抗原特异性抗体的许多多核苷酸，用于产生人源化Lewis B抗原特异性抗体的表达载体和用于重组产生人源化抗体的宿主细胞。 本发明还提供使用人源化Lewis B抗原特异性抗体检测癌细胞（体外和体内）的方法。 另外，本发明提供了使用Lewis b抗原特异性抗体治疗癌症的方法。

公开(公告)号：US5795961A

公开(公告)日：1998-08-18

申请号：US388672

申请日：1995-02-14

申请人： T. Paul Wallace ,  William J. Harris ,  Frank J. Carr ,  Lloyd J. Old ,  Sydney Welt ,  Kunio Kitamura

发明人： T. Paul Wallace ,  William J. Harris ,  Frank J. Carr ,  Lloyd J. Old ,  Sydney Welt ,  Kunio Kitamura

IPC分类号： C07K16/30 ,  C07K14/00 ,  A61K38/16 ,  C12P21/08

CPC分类号： C07K16/30 ,  A61K2039/505 ,  C07K2317/24 ,  C07K2319/00

摘要： The invention provides for the production of several humanized murine antibodies specific for the Lewis b antigen, which is recognized by the murine antibody 58-1066. The antigen is expressed on cell lines from colon, lung, bladder, breast, renal, pancreatic and ovarian cancers. The expression of the antigen is greatly increased in cancer tissues as compared to its expression in the corresponding normal tissue. The invention also provides for numerous polynucleotide encoding humanized Lewis b antigen specific antibodies, expression vectors for producing humanized Lewis b antigen specific antibodies, and host cells for the recombinant production of the humanized antibodies. The invention also provides methods for detecting cancerous cells (in vitro and in vivo) using humanized Lewis b antigen specific antibodies. Additionally, the invention provides methods of treating cancer using Lewis b antigen specific antibodies.

摘要翻译： 本发明提供了生产针对Lewis b抗原特异性的几种人源化鼠抗体，其被鼠抗体58-1066识别。 抗原在结肠癌，肺癌，膀胱癌，乳腺癌，肾癌，胰腺癌和卵巢癌的细胞系中表达。 与其相应的正常组织中的表达相比，癌组织中抗原的表达大大增加。 本发明还提供编码人源化Lewis B抗原特异性抗体的许多多核苷酸，用于产生人源化Lewis B抗原特异性抗体的表达载体和用于重组产生人源化抗体的宿主细胞。 本发明还提供使用人源化Lewis B抗原特异性抗体检测癌细胞（体外和体内）的方法。 另外，本发明提供了使用Lewis b抗原特异性抗体治疗癌症的方法。

公开(公告)号：US5646253A

公开(公告)日：1997-07-08

申请号：US207996

申请日：1994-03-08

申请人： Thomas Paul Wallace ,  William Joseph Harris ,  Francis Joseph Carr ,  Wolfgang J. Rettig ,  Pilar Garin-Chesa ,  Lloyd J. Old

发明人： Thomas Paul Wallace ,  William Joseph Harris ,  Francis Joseph Carr ,  Wolfgang J. Rettig ,  Pilar Garin-Chesa ,  Lloyd J. Old

IPC分类号： G01N33/574 ,  G01N33/68 ,  C07K16/46

CPC分类号： G01N33/6854 ,  G01N33/57484 ,  G01N33/6833

摘要： The invention provides for the production of several humanized murine antibodies specific for the antigen LK26, which is recognized by the murine antibody LK26. This antigen is expressed on all choriocarcinoma, teratocarcinoma and renal cancer cell lines whereas it is not expressed on cell lines of leukaemias, lymphomas, neuroectodermally-derived and epithelial tumour cell lines (excepting a small subset of epithelial cell lines). Furthermore, whereas renal cancer cell lines express the LK26 antigen, normal renal epithelial cells do not. Similarly, with the exception of the trophoblast, all normal adult and fetal tissues tested are negative for the LK26 phenotype. The invention also provides for numerous polynucleotide encoding humanized LK26 specific antibodies, expression vectors for producing humanized LK26 specific antibodies, and host cells for the recombinant production of the humanized antibodies. The invention also provides methods for detecting cancerous cells (in vitro and in vivo) using humanized LK26 specific antibodies. Additionally, the invention provides methods of treating cancer using LK26 specific antibodies.

摘要翻译： 本发明提供了针对抗原LK26特异的几种人源化鼠抗体的产生，其被鼠抗体LK26识别。 该抗原在所有绒毛膜癌，畸胎癌和肾癌细胞系中表达，而不在白血病，淋巴瘤，神经外胚层衍生的和上皮性肿瘤细胞系的细胞系（除了上皮细胞系的一小部分之外）上表达。 此外，肾癌细胞株表达LK26抗原时，肾上皮细胞不正常。 类似地，除了滋养层之外，所有正常的成年和胎儿组织检测对于LK26表型是阴性的。 本发明还提供编码人源化LK26特异性抗体的许多多核苷酸，用于产生人源化LK26特异性抗体的表达载体和用于重组产生人源化抗体的宿主细胞。 本发明还提供了使用人源化LK26特异性抗体检测癌细胞（体外和体内）的方法。 另外，本发明提供使用LK26特异性抗体治疗癌症的方法。

公开(公告)号：US4686859A

公开(公告)日：1987-08-18

申请号：US926309

申请日：1986-10-31

申请人： Paul Wallace

发明人： Paul Wallace

IPC分类号： B25B23/14 ,  B25B23/147 ,  F16B31/02 ,  G01L5/24 ,  G01L1/04

CPC分类号： B25B23/14 ,  B25B23/147 ,  F16B31/025 ,  G01L5/24

摘要： A method of measuring the load in a member subjected to longitudinal stress, a load measuring device and a fastener tightening device using the method of measuring, a load indicating member and a load indicating fastener for use in conjunction with the method of measuring, a method of making the load indicating fastener, and a method of tightening the load indicating fastener. A preselected end of a pin is secured to a shank of a load indicating member, such as a load indicating fastener, in a manner such that the pin is unaffected by the elastic deformation of the shank in response to longitudinal stress. Coplanar first and second flat surfaces are formed, respectively, adjacent to the longitudinal ends of the pin and the shank furthest from the preselected end of the pin such as to provide reference surfaces for the measurement of the elongation of the shank in response to longitudinal stress.

摘要翻译： 一种测量受到纵向应力的构件的负荷的方法，负荷测量装置和使用测量方法的紧固件紧固装置，与测量方法结合使用的负载指示构件和负载指示紧固件的方法 制造负载指示紧固件的方法，以及紧固负载指示紧固件的方法。 销的预选端被固定到诸如负载指示紧固件的负载指示构件的柄上，使得销不受轴的响应于纵向应力的弹性变形的影响。 分别形成共面的第一和第二平坦表面，邻近销的纵向端部和距离销的预选端部最远的柄部，以提供用于响应于纵向应力来测量柄部的伸长的参考表面 。

公开(公告)号：US08404159B2

公开(公告)日：2013-03-26

申请号：US12920319

申请日：2009-02-24

申请人： Simon James Goddard ,  Paul Wallace

发明人： Simon James Goddard ,  Paul Wallace

IPC分类号： H01B1/00 ,  H01L29/08 ,  H01L51/40

CPC分类号： H01L51/0007 ,  H01L51/0005 ,  H01L51/0038 ,  H01L51/0039 ,  H01L51/5012 ,  H01L51/5048 ,  H01L51/5088 ,  H01L51/56 ,  Y10T428/24802

摘要： A composition suitable for fabricating an electronic device such as an OLED using an ink-jet printing technique comprises a conducting or semi-conducting organic material and a solvent, the solvent having a boiling point of greater than 250° C. and a viscosity of less than 5 cPs. The composition preferably has a viscosity in the range between 0.1 and 20 cPs, and the solvent preferably has the formula: where R represents a C6 to C11 alkyl. The high boiling point of the solvent allows the “ink” to remain wet for a longer time after printing. This provides better process control during drying, resulting in more uniform films and greater control over the film profile. The low viscosity of the solvent enables jetting of the composition at high frequencies.

摘要翻译： 适用于使用喷墨打印技术制造诸如OLED的电子器件的组合物包括导电或半导电有机材料和溶剂，溶剂的沸点大于250℃，粘度较低 超过5个cPs。 该组合物优选具有在0.1至20cPs之间的粘度，并且溶剂优选具有下式：其中R表示C6至C11烷基。 溶剂的高沸点允许油墨在印刷后更长时间保持湿润。 这在干燥过程中提供了更好的工艺控制，导致更均匀的膜和对膜轮廓的更大的控制。 溶剂的低粘度使得能够以高频喷射组合物。

公开(公告)号：US08084767B2

公开(公告)日：2011-12-27

申请号：US12376111

申请日：2007-08-01

申请人： Paul Wallace ,  Simon Goddard

发明人： Paul Wallace ,  Simon Goddard

IPC分类号： H01L51/00

CPC分类号： H01L51/0005 ,  H01L27/3246 ,  H01L27/3283 ,  H01L51/0007 ,  H01L51/0037 ,  H01L51/5088

摘要： A composition for use in the manufacture of an opto-electrical device, the composition comprising: a conductive or semi-conductive organic material; a solvent; and a first additive, wherein the first additive is an alcohol ether having a boiling point lower than 170° C.

摘要翻译： 一种用于制造光电器件的组合物，所述组合物包含：导电或半导电有机材料; 溶剂; 和第一添加剂，其中第一添加剂是沸点低于170℃的醇醚。

公开(公告)号：US08043722B2

公开(公告)日：2011-10-25

申请号：US10582459

申请日：2004-12-13

申请人： Paul Wallace ,  Carl Towns

发明人： Paul Wallace ,  Carl Towns

IPC分类号： H01L51/54

CPC分类号： C08G73/026 ,  C08G61/122 ,  C08G61/123 ,  C08G61/126 ,  C08G73/00 ,  C08G79/02 ,  C09K11/06 ,  C09K2211/1014 ,  C09K2211/1433 ,  H01L51/0035 ,  H01L51/0036 ,  H01L51/0043 ,  H01L51/0059 ,  H05B33/14

摘要： An optionally substituted oligomer or polymer comprising a repeat unit of formula (I); wherein each Ar1 and Ar3 is the same or different and independently represents an optionally substituted aryl or heteroaryl; n is at least 1; Ar2 represents an optionally substituted aryl or heteroaryl comprising a linking ring to which the two nitrogen atoms are both directly linked; and at least one of Ar2 and either or both of Ar1 is substituted with at least one substituent.

摘要翻译： 包含式（I）的重复单元的任选取代的低聚物或聚合物; 其中每个Ar 1和Ar 3相同或不同并且独立地表示任选取代的芳基或杂芳基; n至少为1; Ar 2表示任选取代的芳基或杂芳基，其包含两个氮原子直接连接的连接环; 并且Ar 2中的至少一个和Ar 1中的任一个或两个被至少一个取代基取代。

公开(公告)号：US20110008590A1

公开(公告)日：2011-01-13

申请号：US12920319

申请日：2009-02-24

申请人： Simon Goddard ,  Paul Wallace

发明人： Simon Goddard ,  Paul Wallace

IPC分类号： H01B1/12 ,  B32B3/10 ,  H01L51/54

CPC分类号： H01L51/0007 ,  H01L51/0005 ,  H01L51/0038 ,  H01L51/0039 ,  H01L51/5012 ,  H01L51/5048 ,  H01L51/5088 ,  H01L51/56 ,  Y10T428/24802

摘要： A composition suitable for fabricating an electronic device such as an OLED using an ink-jet printing technique comprises a conducting or semi-conducting organic material and a solvent, the solvent having a boiling point of greater than 250° C. and a viscosity of less than 5 cPs. The composition preferably has a viscosity in the range between 0.1 and 20 cPs, and the solvent preferably has the formula: where R represents a C6 to C11 alkyl. The high boiling point of the solvent allows the “ink” to remain wet for a longer time after printing. This provides better process control during drying, resulting in more uniform films and greater control over the film profile. The low viscosity of the solvent enables jetting of the composition at high frequencies.

摘要翻译： 适用于使用喷墨打印技术制造诸如OLED的电子器件的组合物包括导电或半导电有机材料和溶剂，溶剂的沸点大于250℃，粘度较低 超过5个cPs。 该组合物优选具有在0.1至20cPs之间的粘度，并且溶剂优选具有下式：其中R表示C6至C11烷基。 溶剂的高沸点允许“油墨”在印刷后保持较长时间的湿润。 这在干燥过程中提供了更好的工艺控制，导致更均匀的膜和对膜轮廓的更大的控制。 溶剂的低粘度使得能够以高频喷射组合物。